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261
3D echocardiography derived reference values and determinants of left ventricular twist and torsion from the population-based STAAB cohort study
Published 2025-02-01“…LV rotation is determined by a complex interplay of sub-endocardial and sub-epicardial fibers which might be affected differentially by potential risk factors. …”
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262
The role of molecular biomarkers in the diagnosis, prognosis, and treatment stratification of oral squamous cell carcinoma: A comprehensive review
Published 2025-03-01“…An extensive summary of the function of molecular biomarkers in OSCC diagnosis, prognosis, and medical care stratification is given in this article. …”
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263
SF3B4 is decreased in pancreatic cancer and inhibits the growth and migration of cancer cells
Published 2017-03-01“…Taken together, these findings demonstrated that splicing factor 3b subunit 4 acted as a suppressive role in pancreatic cancer and indicated that restoring the function of splicing factor 3b subunit 4 might be a strategy for cancer therapy.…”
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264
Regulation of L-Lactate in Glutamate Excitotoxicity Under Cerebral Ischemia: Pathophysiology and Preventive Strategy
Published 2025-06-01“…In addition, L-lactate promotes the function of mitochondrial calcium uniporter complex (MCUC), which quickly depletes intracellular Ca<sup>2+</sup> in postsynaptic neurons. …”
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265
Interaction between glutathione S‐transferase M1‐null/present polymorphism and adjuvant chemotherapy influences the survival of breast cancer
Published 2018-09-01“…It is suggested that the GSTM1‐present genotype might prevent progression in breast cancer patients. …”
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266
Reprogramming of H3K27me3 is critical for acquisition of pluripotency from cultured Arabidopsis tissues.
Published 2012-08-01“…The Polycomb Repressive Complex 2 (PRC2) is known to function in establishing H3K27me3. …”
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267
A Lightweight YOLOv8s Algorithm for Ceiling Fan Blade Defect Detection With Optimized Pruning and Knowledge Distillation
Published 2025-01-01“…The proposed hybrid loss function promotes sufficient knowledge transfer of intermediate and output features from the teacher to the student network, thus preserving defect identification capabilities that might otherwise degrade through knowledge distillation. …”
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268
Two chemosensory proteins in Aleurocanthus spiniferus are involved in the recognition of host VOCs
Published 2024-12-01“…Abstract Background CSPs are known for their complex and arguably obscure function(s), particularly in chemical olfaction. …”
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269
Real-Time Fluorescence Measurements of ROS and [Ca2+] in Ischemic / Reperfused Rat Hearts: Detectable Increases Occur only after Mitochondrial Pore Opening and Are Attenuated by Is...
Published 2016-01-01“…If earlier IP-sensitive changes occur that might trigger initial mPTP opening they are below our limit of detection. …”
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270
Discussion Points of the Remote Sensing Study and Integrated Analysis of the Archaeological Landscape of Rujm el-Hiri
Published 2024-11-01“…Although tumuli share similar forms and likely construction techniques, their spatial distribution, connections to other archaeological features, and the statistical distribution in their sizes suggest that they might serve diverse functions. The objects and patterns identified may be used for further training neural networks to analyze their spatial properties and interrelationships. …”
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271
Astrocytes phenomics as new druggable targets in healthy aging and Alzheimer’s disease progression
Published 2025-01-01“…The morphological and functional heterogeneity of astrocytes in different brain regions may be related to their different housekeeping functions. …”
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272
Identification of biomarkers related to propionate metabolism in schizophrenia
Published 2025-04-01“…PurposeSchizophrenia (SCZ) is a severe mental disorder with complex etiology. Research shows propionate metabolism is crucial for neurological function and health. …”
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273
A non-dominated sorting based multi-objective neural network algorithm of ethylene glycol hydrogenation reactor in energy reduction
Published 2024-12-01“…The intermediate points in the Pareto Front PF for various three-objective situations provide lower energy costs than the bi-objective function. While bi-objective optimization might seem more straightforward, the intermediate points on the Pareto Front in three-objective optimization can provide lower energy costs due to more effective balancing of trade-offs, richer exploration of the solution space, capturing complex interdependencies, and offering more robust and flexible solutions. …”
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274
Neural Networks vs. Regression: A Comparative Analysis in Medical Data Processing
Published 2025-05-01“…The risk of post-COVID-19 type 2 diabetes (glycaemia at 4 and at 12 months post-COVID as function of metabolic parameters) was predicted using both linear regression and FFNN. …”
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275
The commonly used antibiotic streptomycin reduces protein synthesis and differentiation in cultured C2C12 myotubes
Published 2025-06-01“…Because streptomycin inhibits bacterial protein synthesis, streptomycin might also have off‐target effects on muscle cell function. …”
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276
Infection with novel duck reovirus induces stress granule and methylation-mediated host translational shutoff in Muscovy ducklings
Published 2024-11-01“…We found that both in vivo and in vitro, the translation efficiency of RNA modified with m6A could be significantly reduced by σB, a structural protein component of NDRV HN10. Furthermore, σB might simultaneously interact with the stress granule complex CAPRIN1 and G3BP1 and the m6A reader protein YTHDF1/3. …”
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277
Insights on Natural Membrane Characterization for the Rational Design of Biomimetic Drug Delivery Systems
Published 2025-06-01“…They are composed of a complex lipid bilayer embedded with proteins, allowing them to perform multiple functions like maintaining the cell structure, regulating which substances enter or leave the cell, and intercellular communication. …”
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278
Quantitative Assessment of the Uncertainty in Aerosol Optical Property Inversion due to Different Surface Reflection Models
Published 2025-01-01“…Improving the accuracy of AAOD inversion might reduce the uncertainty in AAE.…”
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279
Photometric Determination of Unresolved Main-sequence Binaries in the Pleiades: Binary Fraction and Mass-ratio Distribution
Published 2025-01-01“…The variations of f _b and q with ${{ \mathcal M }}_{1}$ reveal a complex binary distribution within the Pleiades, which might be attributed to a combination of primordial binary formation mechanisms, dynamical interactions, and the observational limit of photometric binaries imposed by ${q}_{{\rm{lim}}}({{ \mathcal M }}_{1})$ .…”
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280
Expression of LTR and LINE1 transposable elements defines atypical teratoid/rhabdoid tumor subtypes
Published 2025-07-01“…The sole recurrent biallelic loss-of-function mutation in SMARCB1 in ATRTs, a core component of the SWI/SNF chromatin remodeling complex, raises the question of how TE transcription contributes to ATRT development. …”
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