-
461
Unravelling the Enigma of Highly Superior Autobiographical Memory: Signs, Symptoms and Treatment Perspectives: A Narrative Review
Published 2025-01-01“…Currently listed on the global diagnosis list up to 2024, with only 62 documented cases, HSAM presents a fascinating cognitive and neurological complexity, including increased functional connectivity within some brain regions, particularly the left temporoparietal junction. …”
Get full text
Article -
462
Transcriptome-derived networks reconstruct distinct immune strategies to counteract fungal infection under different iron availability between Arabidopsis and rice
Published 2025-03-01“…Here, we report antagonistic immune phenotypes in Arabidopsis thaliana and Oryza sativa infected by Colletotrichum higginsianum and Magnaporthe oryzae under different Fe nutritional status. Functional and topological analysis of transcriptional networks unveiled differences in complexity and hierarchy for similar biological functions, as well as in Fe usage and distribution, between the two pathosystems, with a focus on the plant side. …”
Get full text
Article -
463
-
464
Improved Binary Grey Wolf Optimization Approaches for Feature Selection Optimization
Published 2025-01-01“…Both S-shaped and V-shaped binary transfer functions were used to convert the continuous solutions obtained from each proposed approach to their corresponding binary versions. …”
Get full text
Article -
465
Phase-lags in large scale brain synchronization: Methodological considerations and in-silico analysis.
Published 2018-07-01“…Architecture of phase relationships among neural oscillations is central for their functional significance but has remained theoretically poorly understood. …”
Get full text
Article -
466
Sustainability Through Directed Change in the Visionary University: From Predicting to Producing the Future
Published 2020-08-01“…The sustainability of a university can be questioned from the perspective of three functional goals, henceforth setting the analytical framework: (i) the development of suited knowledge (dynamic and evolving, mirroring the complexity of the socioeconomic environment, definitely internationalised and future-oriented), (ii) the development of students’ skills, as future workforce (valuing the knowledge) and (iii) the development of institutional capacities, in agile constructions (adequate to face the first two challenges). …”
Get full text
Article -
467
Divergent impact of long-term anthropogenic nitrogen inputs on global particulate and mineral-associated organic carbon
Published 2025-06-01“…Anthropogenic nitrogen inputs increase the levels of reactive nitrogen, significantly influencing SOC dynamics. Given the complexity of SOC, it remains unclear how its key components—particulate organic carbon (POC) and mineral-associated organic carbon (MAOC)—respond to nitrogen addition over time, due to their fundamental differences in formation, persistence, and functions. …”
Get full text
Article -
468
Adsorption Properties of Fishbone and Fishbone-Derived Biochar for Cadmium in Aqueous Solution
Published 2024-11-01“…Moreover, the potential adsorption mechanisms of Cd<sup>2+</sup> on FBM and fishbone-derived biochar might be related to pore filling, ion exchange, complexation with oxygen functional groups, and precipitation with the minerals on the biochar surface. …”
Get full text
Article -
469
Chloroquine induces eryptosis in P. falciparum-infected red blood cells and the release of extracellular vesicles with a unique protein profile
Published 2025-05-01“…Notably, the outward budding and blebbing of the iRBC plasma membrane led to the formation of EVs, which are complex structures with unique functional properties. …”
Get full text
Article -
470
Cancer-associated foam cells hamper protective T cell immunity and favor tumor progression in human colon carcinogenesis
Published 2024-10-01“…Background Colorectal cancer (CRC) remains a significant healthcare burden worldwide, characterized by a complex interplay between obesity and chronic inflammation. …”
Get full text
Article -
471
PO48 | Thrombotic risk evaluation and thrombophilia testing in beta-thalassemia patients: a retrospective cohort analysis from a reference regional center
Published 2025-08-01“…Nineteen had complete screening (including both functional and genetic testing), while 18/65 and 28/65 patients had partial genetic and functional screening, respectively (Table 1). …”
Get full text
Article -
472
DYSFUNCTION OF COMPLEMENT SYSTEM IN FAMILIAL MEDITERRANEAN FEVER
Published 2014-07-01“…From the data obtained, following conclusions have been made: 1) pathogenesis of FMF is characterized by a complement dysfunction, including hyperactivation of classical complement pathway and hypoactivation state of alternative pathway; 2) alterations in functional activities of classical and alternative complement activation pathways in FMF are interdependent; 3) the alternative pathway is suppressed on the initial stage of its activation; 4) high blood levels of C-reactive protein, serum amyloid P component, and circulating immune complexes, associated with FMF, might be responsible for hyperactivation of classical complement pathway in this disease.…”
Get full text
Article -
473
DATA MINING IN RELATIONAL SYSTEMS
Published 2020-09-01“…The search for association rules is far from a trivial task, as it might seem at first glance. One of the problems is the algorithmic complexity of finding frequently occurring itemsets, since as the number of items grows, the number of potential itemsets grows exponentially.…”
Get full text
Article -
474
A Conserved Interaction between a C-Terminal Motif in Norovirus VPg and the HEAT-1 Domain of eIF4G Is Essential for Translation Initiation.
Published 2016-01-01“…These observations define important structural details of a functional interaction between norovirus VPg and eIF4G and reveal a binding interface that might be exploited as a target for antiviral therapy.…”
Get full text
Article -
475
Streamlining cVEP Paradigms: Effects of a Minimized Electrode Montage on Brain–Computer Interface Performance
Published 2025-05-01“…Three experimental conditions were tested: a baseline 16-electrode configuration, a reduced 6-electrode setup without retraining, and a reduced 6-electrode setup with retraining. (3) Results: Our results indicate that, on average, performance declines with fewer electrodes; nonetheless, retraining restored near-baseline mean Information Transfer Rate (ITR) and accuracy for those participants for whom the system remained functional. The results reveal that for a substantial number of participants, the classification pipeline fails after electrode removal, highlighting individual differences in the cVEP response characteristics or inherent limitations of the classification approach. (4) Conclusions: Ultimately, this suggests that minimal cVEP-BCI electrode setups capable of reliably functioning across all users might only be feasible through other, more flexible classification methods that can account for individual differences. …”
Get full text
Article -
476
LGBT Actors, Ritual and Martial Arts Groups, and State-Building in Post-Conflict Timor-Leste
Published 2025-02-01“…Taking these common assumptions for granted, one would seriously underestimate the complexity of ritual/martial arts groups (RAGs and MAGs) in Timor-Leste. …”
Get full text
Article -
477
The meaning of “total pain” in the context of living and dying with dementia
Published 2025-04-01“…Using a palliative care framework and existing literature, we critically consider the bio-psycho-socio-spiritual impact of dementia, to explore how total pain might manifest and be experienced in this context.Findings and interpretationWe highlight the complexity, nuance and socially contingent nature of the impact of living and dying with dementia. …”
Get full text
Article -
478
miR-210 loss leads to widespread phenotypic and gene expression changes in human 293T cells
Published 2024-12-01“…Surprisingly, the mRNA levels of most previously reported miR-210 target genes were not induced upon miR-210 KO, suggesting a need to reexamining and studying human miR-210 functions directly and comprehensively. Thus, our work established a human cellular system and opportunity to unravel the complexity of the regulatory networks by miR-210.…”
Get full text
Article -
479
Computational insights in CD58 binding to ASFV CD2v and in silico optimization of nanobody designs against the interface
Published 2025-01-01“…Results: Simulations report poor affinity of CD2v to CD58 in the "canonical" pose and present a novel pose backed by docking, simulation data, and recent observations. The new site might have developed due to immunological considerations and may reproduce observed lymphocyte non-proliferation by hijacking CD58-CD2 ruler functions in immunological synapse formation. …”
Get full text
Article -
480
Rumen DNA virome and its relationship with feed efficiency in dairy cows
Published 2025-01-01“…Conclusions This study constructed a comprehensive rumen DNA virome profile for Holstein dairy cows, elucidating the structural and functional complexity of rumen viruses, the roles of AMGs, and vOTU-hMAG linkages. …”
Get full text
Article