Exploring Molecular Pathways in Refractive Errors Associated with Inherited Retinal Dystrophies by Fabiana D’Esposito, Caterina Gagliano, Alessandro Avitabile, Giuseppe Gagliano, Mutali Musa, Matteo Capobianco, Federico Visalli, Edoardo Dammino, Marco Zeppieri, Maria Francesca Cordeiro

“…However, the prevalence statistics might differ significantly depending on the exact type of dystrophy and the demographic being examined. …”
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A double-edged sword in antiviral defence: ATG7 binding dicer to promote virus replication by Yaotang Wu, Yang Wu, Chenlu Wang, Ningna Xiong, Wenxin Ji, Mei Fu, Junpeng Zhu, Zhixin Li, Jian Lin, Qian Yang

“…Our findings suggested that virus infection might trigger the upregulation of autophagy and downregulation of the RNAi pathway, revealing a complex interaction between these two biological processes in the defence against viral replication.…”
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Human Development XIII: The Connection Between the Structure of the Overtone System and the Tone Language of Music. Some Implications for Our Understanding of the Human Brain by Søren Ventegodt, Tyge Dahl Hermansen, Isack Kandel, Joav Merrick

“…The functioning brain behaves like one highly-structured, coherent, informational field. …”
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Kinesthetic illusions induced by muscle tendon vibration: The orientation of the vibration motor as a new methodological factor? by Lydiane Lauzier, Jacques Abboud, François Nougarou, Louis-David Beaulieu

“…Distoproximal rotation was more effective to elicit the expected illusions of wrist extension, compared to the lateromedial orientation that more often caused complex and variable perceptions of movement. Distoproximal rotation should thus be preferred if clear and reproducible perceptions are required and lateromedial might serve as a way of creating illusions more akin to everyday functional movements. …”
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The dual role of microglia in Alzheimer’s disease: from immune regulation to pathological progression by Cong He, Baojiang Chen, Hecai Yang, Xiaoqing Zhou

“…Despite extensive research, the role of microglia in AD remains complex and dual. The aim of this review is to summarize the most recent advances in research regarding the dual role of microglia in AD concerning both immunomodulation and pathological progression by considering mechanisms of activation of microglia, effects on Aβ clearance, tau pathology, and impacts due to genetic variations on microglial functions. …”
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Alteration of phycobilisome excitation energy transfer properties in response to attenuations in peripheral electron flow by Zhanjun Guo, Sharon L. Smolinski, Paul W. King, Carolyn E. Lubner

“…PCC 6803 (S. 6803), two types of phycobilisome (PBS) complexes, CpcG-PBS and CpcL-PBS, function to harvest light energy for photosynthetic reaction centers (RCs), photosystem I (PSI) and photosystem II (PSII). …”
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Immunoglobulin Free Light Chain Dimers in Human Diseases by Batia Kaplan, Avi Livneh, Ben-Ami Sela

“…The presence of tetra- and trimolecular complexes formed due to dimer-dimer and dimer-monomer interactions was detected in the myeloma serum. …”
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Solar Biota. Co-Living with Solar Ecologies by Suzanna Törnroth

“…The central question to this study is thus – How might a relational adoption of solar PVs increase multispecies flourishing? …”
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Assessment of Classical Force-Fields for Graphene Mechanics by Zhiwei Ma, Yongkang Tan, Xintian Cai, Xue Chen, Tan Shi, Jianfeng Jin, Yifang Ouyang, Qing Peng

“…Molecular dynamics simulation is a well-established and useful tool for investigating graphene’s atomic structure and dynamic behavior at the nanoscale without requiring expensive and complex experiments. The accuracy of the molecular dynamics simulation depends on the potential functions. …”
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A high throughput method for isolation of plasmatocytes from hemolymph of adult Drosophila. by Mansi Yadav, Jassika Gupta, Debalina Chatterjee, Parul Mittal, Anju Shrivastava, Namita Agrawal

“…Macrophages are essential innate immune system components, exhibiting diverse functions crucial for disease prevention. While much is known about their role in innate immunity, studying their functional versatility remains a challenge. …”
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Case report: Clinical and genetic characteristics of heterozygous CaSR variants in three Chinese females with familial hypocalciuric hypercalcemia type 1: a report of three cases by Ruxuan Zhang, Ruxuan Zhang, Tingting Hu, Shuai Wang, Yiping Cheng, Dandan Luo, Dongmei Zheng, Xinli Zhou, Xinli Zhou, Xinli Zhou

“…The analysis of the conservation of homologous species and the prediction of protein structure for all variant sites demonstrated that due to the heterozygous variants in CaSR, relatively conserved amino acids were altered, affecting the interaction forces between adjacent amino acids, resulting in changes in the protein structure, which might affect the function of the protein.ConclusionIn conclusion, we report three cases of FHH1 with different heterozygous variant sites in the CaSR gene. …”
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Amantadine modulates novel macrophage phenotypes to enhance neural repair following spinal cord injury by Shijie Yang, Beibei Yu, Qing Zhang, Yongfeng Zhang, Longhui Fu, Bisheng Zhou, Haining Wu, Jianzhong Li, Shouping Gong

“…Abstract Background Spinal cord injury (SCI) triggers a complex inflammatory response that impedes neural repair and functional recovery. …”
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Comparative Transcriptomic Analysis Between High- and Low-Growth-Rate Meat-Type Rabbits Reveals Key Pathways Associated with Muscle Development by Chao Yang, Lingxi Zhu, Li Tang, Xiangyu Zhang, Min Lei, Xiaohong Xie, Cuixia Zhang, Dingsheng Yuan, Congyan Li, Ming Zhang

“…GO (Gene Ontology) analysis of DEGs indicated DEGs in the thigh muscle were enriched in these terms related to biological processes of muscle cell migration and smooth muscle cell migration, cellular components of sarcomere, myofibril, and actin filament bundle, while DEGs in <i>longissimus dorsi</i> muscle were enriched in these terms associated with biological processes of muscle cell migration, smooth muscle cell migration and muscle structure development, cellular component of actin cytoskeleton, contractile fiber, myofibril, myosin complex and molecular function of actin filament binding. …”
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SOX7: Autism associated gene identified by analysis of multi-Omics data. by Samantha Gonzales, Jane Zizhen Zhao, Na Young Choi, Prabha Acharya, Sehoon Jeong, Xuexia Wang, Moo-Yeal Lee

“…Thus, it is unclear which of these mutations might be functional and thus potentially causal variants. …”
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Screening and Analysis of Proteins Interacting with TaPDK from Physiological Male Sterility Induced by CHA in Wheat by Long-yu ZHANG, Gai-sheng ZHANG, Xin-liang ZHAO, Shu-ling YANG

“…Collectively, these datas indicated that the majority of candidate proteins might be related to pollen abortion in PHYMS lines, which further suggested that TaPDK plays multiple roles in pollen development, besides participating in regulating pyruvate dehydrogenase complex activity.…”
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Antagonist actions of CMK-1/CaMKI and TAX-6/calcineurin along the C. elegans thermal avoidance circuit orchestrate adaptation of nociceptive response to repeated stimuli by Martina Rudgalvyte, Zehan Hu, Dieter Kressler, Jörn Dengjel, Dominique A Glauser

“…These findings highlight a complex interplay of signaling modules that modulate thermal nociception and adaptation, offering new insights into potentially conserved mechanisms that shape nociceptive plasticity and pain (de)sensitization in more complex nervous systems.…”
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Different Stability and Proteasome-Mediated Degradation Rate of SMN Protein Isoforms. by Denise Locatelli, Mineko Terao, Mami Kurosaki, Maria Clara Zanellati, Daniela Rita Pletto, Adele Finardi, Francesca Colciaghi, Enrico Garattini, Giorgio Stefano Battaglia

“…However, to what extent the impairment of these two SMN functions contributes to SMA pathogenesis remains unknown. …”
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Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7. by Leonie Unterholzner, Rebecca P Sumner, Marcin Baran, Hongwei Ren, Daniel S Mansur, Nollaig M Bourke, Felix Randow, Geoffrey L Smith, Andrew G Bowie

“…Thus C6 contributes to VACV virulence and might do so via the inhibition of PRR-induced activation of IRF3 and IRF7.…”
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Urotensin-II: More Than a Mediator for Kidney by Ayşe Balat, Mithat Büyükçelik

“…Recent studies suggest that U-II may have a possible autocrine/paracrine functions in kidney and may be an important target molecule in studying renal pathophysiology. …”
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Alimentation et gestion de l’eau sur la colline de Fourvière à Lyon : les aménagements hydrauliques, la ville et ses monuments by Aldo Borlenghi, Éric Leroy

“…As far as we know, no aqueduct had yet come into operation at that time. Conversely, it might have received its water supply from the Yzeron aqueduct at the time when the complex was transformed during the reigns of Tiberius and Claudius. …”
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