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Two chemosensory proteins in Aleurocanthus spiniferus are involved in the recognition of host VOCs
Published 2024-12-01“…Abstract Background CSPs are known for their complex and arguably obscure function(s), particularly in chemical olfaction. …”
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242
Real-Time Fluorescence Measurements of ROS and [Ca2+] in Ischemic / Reperfused Rat Hearts: Detectable Increases Occur only after Mitochondrial Pore Opening and Are Attenuated by Is...
Published 2016-01-01“…This argues against superoxide production from reduced Complex 1 being a critical mediator of initial mPTP opening during early reperfusion. …”
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243
Discussion Points of the Remote Sensing Study and Integrated Analysis of the Archaeological Landscape of Rujm el-Hiri
Published 2024-11-01“…Although tumuli share similar forms and likely construction techniques, their spatial distribution, connections to other archaeological features, and the statistical distribution in their sizes suggest that they might serve diverse functions. The objects and patterns identified may be used for further training neural networks to analyze their spatial properties and interrelationships. …”
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244
Astrocytes phenomics as new druggable targets in healthy aging and Alzheimer’s disease progression
Published 2025-01-01“…The morphological and functional heterogeneity of astrocytes in different brain regions may be related to their different housekeeping functions. …”
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245
Interaction between glutathione S‐transferase M1‐null/present polymorphism and adjuvant chemotherapy influences the survival of breast cancer
Published 2018-09-01“…It is suggested that the GSTM1‐present genotype might prevent progression in breast cancer patients. …”
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246
Regulation of L-Lactate in Glutamate Excitotoxicity Under Cerebral Ischemia: Pathophysiology and Preventive Strategy
Published 2025-06-01“…In addition, L-lactate promotes the function of mitochondrial calcium uniporter complex (MCUC), which quickly depletes intracellular Ca<sup>2+</sup> in postsynaptic neurons. …”
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247
Identification of biomarkers related to propionate metabolism in schizophrenia
Published 2025-04-01“…PurposeSchizophrenia (SCZ) is a severe mental disorder with complex etiology. Research shows propionate metabolism is crucial for neurological function and health. …”
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248
SF3B4 is decreased in pancreatic cancer and inhibits the growth and migration of cancer cells
Published 2017-03-01“…Taken together, these findings demonstrated that splicing factor 3b subunit 4 acted as a suppressive role in pancreatic cancer and indicated that restoring the function of splicing factor 3b subunit 4 might be a strategy for cancer therapy.…”
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249
A non-dominated sorting based multi-objective neural network algorithm of ethylene glycol hydrogenation reactor in energy reduction
Published 2024-12-01“…The intermediate points in the Pareto Front PF for various three-objective situations provide lower energy costs than the bi-objective function. While bi-objective optimization might seem more straightforward, the intermediate points on the Pareto Front in three-objective optimization can provide lower energy costs due to more effective balancing of trade-offs, richer exploration of the solution space, capturing complex interdependencies, and offering more robust and flexible solutions. …”
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250
Discipline-based Teaching and Identity Expansion – Teacher Education and the Tertiary Vocational Educator in New Zealand
Published 2013-10-01“…With diverse work-based backgrounds, vocational educators undertake their work within the teaching workforce often without a strong sense of their educational position or function and there is little guidance in the complexities and realities of the role. …”
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251
An updated insight into the Sialotranscriptome of Triatoma infestans: developmental stage and geographic variations.
Published 2014-12-01“…As in all hematophagous arthropods, its saliva contains a complex cocktail that assists blood feeding by preventing platelet aggregation and blood clotting and promoting vasodilation. …”
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252
Integrated Information Theory and the Phenomenal Binding Problem: Challenges and Solutions in a Dynamic Framework
Published 2025-03-01“…The solution—that particular entities aggregable from multiple units (‘complexes’) define existence—might work in a static picture, but introduces issues in a dynamic system. …”
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253
The role of molecular biomarkers in the diagnosis, prognosis, and treatment stratification of oral squamous cell carcinoma: A comprehensive review
Published 2025-03-01“…Complex genetic mutations, epigenetic changes, and dysregulated signalling pathways are all part of the aetiology of OSCC. …”
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254
3D echocardiography derived reference values and determinants of left ventricular twist and torsion from the population-based STAAB cohort study
Published 2025-02-01“…LV rotation is determined by a complex interplay of sub-endocardial and sub-epicardial fibers which might be affected differentially by potential risk factors. …”
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255
Overexpression of the microtubule-binding protein CLIP-170 induces a +TIP network superstructure consistent with a biomolecular condensate.
Published 2021-01-01“…Moreover, bioinformatic studies demonstrate that the presence of intrinsically disordered regions is conserved in key +TIPs, implying that these regions are functionally significant. Together, these results indicate that the CLIP-170 induced patches in cells are phase-separated liquid condensates and raise the possibility that the endogenous +TIP network might form a liquid droplet at MT ends or other +TIP locations.…”
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256
Clinical manifestations of dual-gene variants involving ABCA4 in retinal dystrophies
Published 2025-04-01“…Conclusions This study underscores the importance of advanced diagnostic tools and careful genotype evaluation to accurately identify and understand potential complex genetic interactions in IRDs. The observed phenotypes enhance our understanding of how these genes contribute to human retinal function and dysfunction. …”
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257
Dendritic overgrowth and elevated ERK signaling during neonatal development in a mouse model of autism.
Published 2017-01-01“…Since dendritic structure is critical for information integration and relay, our data suggest that altered development of dendrites could potentially contribute to impaired hippocampal function and behavior observed in the BTBR model, and that this might be related to increased activation of the ERK pathway.…”
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258
Bureaucratic Rationalism and The Quiet (R)evolution
Published 1996-01-01“…We can of course pump students full of facts or even brainwash them — but pumping facts is a waste of everybody’s time and washing brains in public is, as Justice Holmes might have told us, dirty business. Learning is what students are there for and all we know about learning is that, on any level of complexity, it is every man for himself and by himself, imposing a perhaps delusive formal pattern on the swirling chaos by a prodigious effort of the individual will. …”
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259
The orchestrated feature of Cornus kousa fruit and gut microbiota against obesity via integrated pharmacology
Published 2024-09-01“…Abstract Cornus kousa fruit (CKF) has been utilized as anti‐obesity supplementation in East Asia, including Korea, and gut microbiota (GM) might have synergistic effects on obesity (OB) via its interplay. …”
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260
A Vehicular Cyber-Physical Framework for Studying the Effects of Multiple Disturbances with Application to Connected Autonomous Vehicles
Published 2025-04-01“…These systems underpin critical infrastructures (CIs), which require coordination to achieve societal functions. However, the exponential growth of CPSs brings about a new challenge as it relates to the security of such systems and by extension any disturbances which might affect their operation. …”
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