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401
Empirical Analysis of Vulnerabilities in Blockchain-based Smart Contracts
Published 2022-06-01“…Conversely, due to the complex semantics of fundamental domain-specific languages and their testability, constructing reliable and secure SC can be extremely difficult. …”
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402
Ion homeostasis in the regulation of intracellular pH and volume of human erythrocytes
Published 2024-08-01“…Background: Cell volume maintenance by regulating the water and ion content is crucial for the survival and functional fullness of human erythrocytes. However, cells are incredibly complex systems with numerous, often competing, reactions occurring simultaneously. …”
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403
Suppressed DNA repair capacity in flight attendants after air travel
Published 2025-05-01“…During air travel, FA are constantly exposed to complex mixtures of mutagens in the flight cabin that may contribute to genomic instability by inducing DNA damage and interfering with DNA repair. …”
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404
Advanced smart assistance with enhancing social interaction and daily activities for visually impaired individuals using deep learning with modified seagull optimization
Published 2025-05-01“…Next, the features are extracted using the Dilated Convolution Block Attention Module with EfficientNet (DCBAM-EfficientNet) module, which derives the intrinsic and complex features. Moreover, the MSGO model is employed to choose the optimal parameter for the DCBAM-EfficientNet module. …”
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405
Monitoring of Biodiversity in the Erbil Governorate -Iraq Using Remote Sensing Data
Published 2025-02-01“…Biologists don't even fully understand the basic organ-level functions of this system, so knowing how a system as complex as this one work and understanding its dynamics are crucial for effective conservation and management of its constituent ecosystems. …”
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406
Biological Characteristics Analysis of Limosilactobacillus reuteri JBR3 and the Effect of Protective Agents on Its Viability
Published 2025-02-01“…JBR3 was freeze-dried under a protective agent complex of skimmed milk powder (9.3 g/100 mL), maltodextrin (2.3 g/100 mL), monosodium glutamate (6.8 g/100 mL), and trehalose (10.0 g/100 mL). …”
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407
Diagnostic tools in maxillofacial fractures: Is there really a need of three-dimensional computed tomography?
Published 2016-05-01“…Introduction: Because of its functional and cosmetic importance, facial injuries, especially bony fractures are clinically very significant. …”
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408
A novel spine tester TO GO
Published 2024-12-01“…While biomechanics are essential for informed decisions on the functionality of the therapy being studied, scientists often choose histological analysis alone. …”
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409
Concerns of older patients and their caregivers in the emergency department.
Published 2020-01-01“…<h4>Background</h4>Older emergency department (ED) patients often have complex problems and severe illnesses with a high risk of adverse outcomes. …”
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410
Exploring the Association Between Human Blood Metabolites and Autism Spectrum Disorder Risk: A Bidirectional Mendelian Randomization Study
Published 2025-03-01“…ABSTRACT Background and Aims Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with a poorly understood etiology. …”
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411
An efficient strategy to promote food waste composting by adding black soldier fly (Hermetia illucens) larvae during the compost maturation phase
Published 2024-12-01“…Furthermore, BSFL introduction might enhance metabolic functions such as glycolysis, inosine monophosphate biosynthesis, gluconeogenesis, and lysine biosynthesis. …”
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412
Bioinformatics Analysis Reveals Diagnostic Markers and Vital Pathways Involved in Acute Coronary Syndrome
Published 2020-01-01“…Protein-protein interaction (PPI) network was mapped in Cytoscape, followed by screening of hub genes based on the Molecular Complex Detection (MCODE) plug-in. Functional Enrichment analysis tool (FunRich) and Database for Annotation, Visualization and Integrated Discovery (DAVID) were used to predict miRNAs and TFs, respectively. …”
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413
Exploring the therapeutic potential of different sources of mesenchymal stem cells: a novel approach to combat burn wound infections
Published 2024-11-01“…On the other hand, a burn wound infection creates an environment that is conducive to the growth of bacteria and might put the patient at risk for sepsis. In addition, scarring is unavoidable, and this results in patients having functional and cosmetic issues. …”
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414
Therapy-induced senescence of glioblastoma cells is determined by the p21CIP1-CDK1/2 axis and does not require activation of DREAM
Published 2025-05-01“…Abstract Therapy-induced senescence (TIS) is a major challenge in cancer therapy as senescent cancer cells provoke local and systemic inflammation and might be the cause of recurrences. Elucidation of pathways leading to TIS is of utmost importance for establishing strategies to counteract this. …”
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415
The biological roles and molecular mechanisms of m6A reader IGF2BP1 in the hallmarks of cancer
Published 2025-09-01“…N6-methyladenosine (m6A) is the most abundant and well-investigated internal RNA modification in eukaryotic RNAs, affecting its target gene expression by controlling RNA localization, splicing, stability, and translation. m6A modifications are regulated by m6A methyltransferase complex, demethylase, and reading proteins. Insulin-like growth factor-2 mRNA-binding protein 1 (IGF2BP1), a member of a conserved family of single-stranded RNA-binding proteins, has recently been identified as a vital m6A reading protein. …”
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416
Identification of palmitoylated biomarkers in non-alcoholic fatty liver disease via integrated bioinformatics analysis and machine learning
Published 2025-08-01“…Abstract Non-alcoholic fatty liver disease (NAFLD) is a global health challenge with complex pathogenesis and limited diagnostic biomarkers. …”
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417
Phenomenology of repetitive and restrictive behaviors and sensory phenomena in neurodevelopmental disorders: an exploratory study
Published 2025-02-01“…Abstract Background Repetitive and restrictive behaviors (RRB) include simple motor stereotypes, tics and complex ritualized and rigid behaviors that are core symptoms in neurodevelopmental disorders such as obsessive–compulsive disorder (OCD), Tourette syndrome (TS) or autism spectrum disorder (ASD). …”
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418
Approaches used to prevent and reduce the use of restrictive practices on adults with learning disabilities: a realist review
Published 2025-05-01“…Conclusion This review highlights that settings providing care for people with a LD are complex care environments, and thus reducing the use of RP is likely to require complex interventions, involving different stakeholders and approaches as our programme theory suggests. …”
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419
Usutu virus NS4A induces autophagy and is targeted by the selective autophagy receptor p62/SQSTM1 for degradation
Published 2025-04-01“…P62 thus plays an antiviral role during USUV infection, although this antiviral effect might also be related to its functions outside the autophagy pathway, such as modulation of the immune response. …”
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420
Identification and validation of oxidative stress-related genes for the diagnosis of sepsis-induced acute lung injury.
Published 2025-01-01“…Sepsis-induced acute lung injury (ALI) is an inflammatory pulmonary condition characterized by a complex pathophysiological mechanism. The development and progression of sepsis-induced ALI are accompanied by significant oxidative damage. …”
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