Unveiling complex brain dynamics during movie viewing via deep recurrent autoencoder model by Kexin Wang, Limei Song, Zhaowei Li, Liting Wang, Xiaowei He, Yudan Ren, Jinglei Lv

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Perspective: How complex in vitro models are addressing the challenges of predicting drug-induced liver injury by K. Taylor, R. Ram, R. Ram, L. Ewart, C. Goldring, G. Russomanno, G. P. Aithal, T. Kostrzewski, C. Bauch, J. M. Wilkinson, J. M. Wilkinson, S. Modi, J. G. Kenna, J. G. Kenna, J. Bailey, J. Bailey

“…Predicting which drugs might have the potential to cause drug-induced liver injury (DILI) is highly complex and the current methods, 2D cell-based models and animal tests, are not sensitive enough to prevent some costly failures in clinical trials or to avoid all patient safety concerns for DILI post-market. …”
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Mutations in human prion-like domains: pathogenic but not always amyloidogenic by Andrea Bartolomé-Nafría, Javier García-Pardo, Salvador Ventura

“…These proteins typically contain prion-like domains of low complexity (PrLDs or LCDs) that govern their assembly into either functional or pathological amyloid fibrils. …”
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Two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins. by Alistair Bailey, Andy van Hateren, Tim Elliott, Jörn M Werner

“…Major histocompatibility complex class I molecules (MHC I) present peptides to cytotoxic T-cells at the surface of almost all nucleated cells. …”
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How (and why) languages became more complex as we evolved more prosocial: the human self-domestication view by Antonio Benítez-Burraco

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Increased maternal genome dosage bypasses the requirement of the FIS polycomb repressive complex 2 in Arabidopsis seed development. by David Kradolfer, Lars Hennig, Claudia Köhler

“…The fertilization independent seed (FIS) Polycomb Repressive Complex 2 (PRC2) is essential for endosperm development; however, the underlying forces that led to the evolution of the FIS-PRC2 remained unknown. …”
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Target organs in patients with post-infarction chronic heart failure: dynamics during complex therapy including beta-adrenoblockers by I. P. Rubesh, L. A. Nekrutenko, A. V. Tuev, Yu. V. Larina, A. V. Agafonov

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Regarder au-delà des élections : l’historicité complexe de la participation politique dans la Libye contemporaine by Chiara Loschi, Chiara Pagano

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Daily Mobility in Metropolitan Areas by Marcela Soto Caro

“…Such day-to-day activities are further shaped by more dynamic and perhaps more subtle influences such as the changing functions of the urban space, increasing socioeconomic fragmentation and segmentation and the inequitable provision of public transport across what is a topographically complex area. …”
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Therapeutic potential of a choline-zinc-vitamin E nutraceutical complex in ameliorating thioacetamide-induced nonalcoholic fatty liver pathology in zebrafish. by Bingbing Cao, Jiali Zhou, Bo Xia, Xiaoqing Li, Rui Wang, Yiqiao Xu, Chunqi Li

“…The results of transcriptomics and quantitative real-time PCR showed that the potential mechanisms underlying the effects of the nutraceutical complex might involve the upregulation of acacia, acsl1a, fbp2 gene expression, and the downregulation of tbc1d1 gene expression. …”
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Age- and Post-Based Complex Analyses of Heart Rate Variability in Young Male Handball Players for Potential Prevention of Overload-induced Injuries by Zita Petrovszki, Olivér Czimbalmos, Vera Gal, Gabor Korosi, Edit Nagy, Rita Mikulan, Gyongyi Horvath

“…The proposed systemic analyses explored age- and post-based differences in autonomic function suggesting that individual alterations from the mean values in different subgroups might indicate changes in performance.…”
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Orai–vascular endothelial-cadherin signaling complex regulates high-glucose exposure-induced increased permeability of mouse aortic endothelial cells by Wei He, Juan Du, Suwen Bai, Yuan Wei, Wenxuan Hou, YanHeng Yao, Junwei Zhu, Yinan Du, Bing Shen, Haoshu Fang

“…Introduction Diabetes-associated endothelial barrier function impairment might be linked to disturbances in Ca2+ homeostasis. …”
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Education and Music Intervention to Reduce Anxiety (EMIRA) in cardiac catheterization: intervention development by Letícia de Carvalho Batista, Marina de Góes Salvetti, Rita de Cassia Gengo e Silva Butcher

“…ARCC is associated with increased myocardial oxygen consumption, blood pressure variability, and increased risk of arrhythmias, leading to higher rates of intraoperative complications and worse physical, emotional, and cognitive functioning. Objective To describe a nurse-led complex intervention (CI) designed to reduce ARCC in adults before a cardiac catheterization (CC). …”
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Characterization of phytoplankton size-structure based productivity, pigment complexes (HPLC/CHEMTAX) and species composition in the Cochin estuary (southwest coast of India): spec... by Meenu Paul, Madhu Nikathithara Velappan, Ullas Nanappan, Vineetha Gopinath, Rehitha Thekkendavida Velloth, Ashwini Rajendran, Maheswari Nair, Anil Peariya

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Vitamin K Epoxide Reductase Complex (VKORC1) Electrochemical Genosensors: Towards the Identification of <i>1639 G>A</i> Genetic Polymorphism by Tiago Barbosa, Stephanie L. Morais, Renato Carvalho, Júlia M. C. S. Magalhães, Valentina F. Domingues, Cristina Delerue-Matos, Hygor Ferreira-Fernandes, Giovanny R. Pinto, Marlene Santos, Maria Fátima Barroso

“…Warfarin inhibits the vitamin K epoxide reductase complex subunit 1 (VKORC1), an enzyme essential for activating vitamin K, in the coagulation cascade. …”
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Abnormal α-synuclein binds to synaptotagmin 13, impairing extracellular vesicle release in synucleinopathies by Yasuo Miki, Shuji Shimoyama, Makoto T. Tanaka, Hanae Kushibiki, Asa Nakahara, Xiaopeng Wen, Masanori Hijioka, Tomoya Kon, Megha Murthy, Tomonori Furukawa, Conceição Bettencourt, Fumiaki Mori, Hiroki Mizukami, Shirushi Takahashi, Mari Tada, Yoshihisa Kitamura, Akiyoshi Kakita, Thomas T. Warner, Koichi Wakabayashi

“…SYT13 was observed to regulate extracellular vesicle release in association with SYT1 and the SNARE complexes in SH-SY5Y cells. SYT13 overexpression in SH-SY5Y cells impaired extracellular vesicle release. …”
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Safety and feasibility evaluation of planning and execution of surgical revascularisation solely based on coronary CTA and FFRCT in patients with complex coronary artery disease: s... by Daniele Andreini, Kaoru Tanaka, Hideyuki Kawashima, Ronny R Buechel, William Wijns, Torsten Doenst, Jonathon Leipsic, Gregg W Stone, Giulio Pompilio, Antonio L Bartorelli, Saima Mushtaq, Enrico Ferrari, Francesco Maisano, Mark La Meir, Johan De Mey, Ulrich Schneider, Ulf Teichgräber, Faisal Sharif, Robbert de Winter, Brian Thomsen, Charles Taylor, Campbell Rogers, Yoshinobu Onuma, Patrick W Serruys

“…Automatic non-invasive assessment of functional coronary anatomy complexity is also evaluated with FFRCT for functional Synergy Between percutaneous coronary intervention With Taxus and Cardiac Surgery Score assessment on CCTA. …”
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Multi-directional deformation for coordinating isotropy and strength-ductility synergy in a CoCrNi alloy by Na Lin, Zhicheng Miao, Mingcan Li, Rumeng Huang, Kaiyuan Zheng, Zhaowen Huang, Donghui Wen, Cong Zhang, Anding Wang

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"My brain freezes and I am blocked again": The subjective experience of post-migration living difficulties influenced by complex posttraumatic stress disorder of Afghan asylum seek... by Jennifer Schiess-Jokanovic, Christine Gösling-Steirer, Viktoria Kantor, Matthias Knefel, Dina Weindl, Brigitte Lueger-Schuster

“…<h4>Background</h4>Potentially traumatic experiences and post-migration living difficulties (PMLDs) undoubtedly leave marks on mental health and psychosocial functioning. While PMLDs are recognised as a risk factor for posttraumatic stress disorder and complex posttraumatic stress disorder (described together here as C/PTSD), recent investigations have found that C/PTSD symptoms might also influence the experience of PMLDs. …”
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More than just a broken limb: Unmasking CRPS in Pakistan by Zahra Aamir Khan

“… Madam, Complex Regional Pain Syndrome (CRPS) is a debilitating pain disorder, usually affecting one limb, and occurring after a trauma. …”
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