Reprogramming of H3K27me3 is critical for acquisition of pluripotency from cultured Arabidopsis tissues. by Chongsheng He, Xiaofan Chen, Hai Huang, Lin Xu

“…The Polycomb Repressive Complex 2 (PRC2) is known to function in establishing H3K27me3. …”
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A Lightweight YOLOv8s Algorithm for Ceiling Fan Blade Defect Detection With Optimized Pruning and Knowledge Distillation by Qinyuan Huang, Chen Fan, Yuqi Sun, Jiaxiong Huang, Wengziyang Jiang

“…The proposed hybrid loss function promotes sufficient knowledge transfer of intermediate and output features from the teacher to the student network, thus preserving defect identification capabilities that might otherwise degrade through knowledge distillation. …”
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Two chemosensory proteins in Aleurocanthus spiniferus are involved in the recognition of host VOCs by Zhifei Jia, Zhenxiang Li, Dandan Li, Zhiwei Kang, Yongyu Xu, Zhenzhen Chen

“…Abstract Background CSPs are known for their complex and arguably obscure function(s), particularly in chemical olfaction. …”
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Real-Time Fluorescence Measurements of ROS and [Ca2+] in Ischemic / Reperfused Rat Hearts: Detectable Increases Occur only after Mitochondrial Pore Opening and Are Attenuated by Is... by Tatyana Andrienko, Philippe Pasdois, Andreas Rossbach, Andrew P Halestrap

“…This argues against superoxide production from reduced Complex 1 being a critical mediator of initial mPTP opening during early reperfusion. …”
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Discussion Points of the Remote Sensing Study and Integrated Analysis of the Archaeological Landscape of Rujm el-Hiri by Olga Khabarova, Michal Birkenfeld, Lev V. Eppelbaum

“…Although tumuli share similar forms and likely construction techniques, their spatial distribution, connections to other archaeological features, and the statistical distribution in their sizes suggest that they might serve diverse functions. The objects and patterns identified may be used for further training neural networks to analyze their spatial properties and interrelationships. …”
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Astrocytes phenomics as new druggable targets in healthy aging and Alzheimer’s disease progression by Daniele Lana, Filippo Ugolini, Ludovica Iovino, Selene Attorre, Maria Grazia Giovannini

“…The morphological and functional heterogeneity of astrocytes in different brain regions may be related to their different housekeeping functions. …”
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Identification of biomarkers related to propionate metabolism in schizophrenia by Weiqi Xie, Zhihong Luo, Jiang Xiao, Xuehua Zhang, Chanjuan Zhang, Ping Yang, Liang Li

“…PurposeSchizophrenia (SCZ) is a severe mental disorder with complex etiology. Research shows propionate metabolism is crucial for neurological function and health. …”
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A non-dominated sorting based multi-objective neural network algorithm of ethylene glycol hydrogenation reactor in energy reduction by Fakhrony Sholahudin Rohman, Sharifah Rafidah Wan Alwi, Dinie Muhammad, Muhamad Nazri Murat, Ashraf Azmi

“…The intermediate points in the Pareto Front PF for various three-objective situations provide lower energy costs than the bi-objective function. While bi-objective optimization might seem more straightforward, the intermediate points on the Pareto Front in three-objective optimization can provide lower energy costs due to more effective balancing of trade-offs, richer exploration of the solution space, capturing complex interdependencies, and offering more robust and flexible solutions. …”
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Repurposing of Some Nucleoside Analogs Targeting Some Key Proteins of the Avian H5N1 Clade 2.3.4.4b to Combat the Circulating HPAI in Birds: An In Silico Approach by Mohd Yasir Khan, Abid Ullah Shah, Nithyadevi Duraisamy, Mohammed Cherkaoui, Maged Gomaa Hemida

“…Additionally, 50 ns molecular dynamics simulations highlighted the structural stability and compactness of the GS441524-PB2/CBD complex, further supporting its potential as a promising antiviral candidate. …”
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An updated insight into the Sialotranscriptome of Triatoma infestans: developmental stage and geographic variations. by Alexandra Schwarz, Nora Medrano-Mercado, Günter A Schaub, Claudio J Struchiner, M Dolores Bargues, Michael Z Levy, José M C Ribeiro

“…As in all hematophagous arthropods, its saliva contains a complex cocktail that assists blood feeding by preventing platelet aggregation and blood clotting and promoting vasodilation. …”
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A Vehicular Cyber-Physical Framework for Studying the Effects of Multiple Disturbances with Application to Connected Autonomous Vehicles by Mohammed Amir, Marine Lincoln, Ramlal Craig, Muddeen Fasil

“…These systems underpin critical infrastructures (CIs), which require coordination to achieve societal functions. However, the exponential growth of CPSs brings about a new challenge as it relates to the security of such systems and by extension any disturbances which might affect their operation. …”
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Clinical manifestations of dual-gene variants involving ABCA4 in retinal dystrophies by Lasse Wolfram, David A. Merle, Laura Kühlewein, Milda Reith, Melanie Kempf, Krunoslav Stingl, Tobias Haack, Pascale Mazzola, Karin Poths, Nicole Weisschuh, Bernd Wissinger, Susanne Kohl, Katarina Stingl

“…Conclusions This study underscores the importance of advanced diagnostic tools and careful genotype evaluation to accurately identify and understand potential complex genetic interactions in IRDs. The observed phenotypes enhance our understanding of how these genes contribute to human retinal function and dysfunction. …”
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Bureaucratic Rationalism and The Quiet (R)evolution by William Twining

“…We can of course pump students full of facts or even brainwash them — but pumping facts is a waste of everybody’s time and washing brains in public is, as Justice Holmes might have told us, dirty business. Learning is what students are there for and all we know about learning is that, on any level of complexity, it is every man for himself and by himself, imposing a perhaps delusive formal pattern on the swirling chaos by a prodigious effort of the individual will. …”
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The orchestrated feature of Cornus kousa fruit and gut microbiota against obesity via integrated pharmacology by Ki‐Kwang Oh, Sang‐Jun Yoon, Sang Youn Lee, Satya Priya Sharma, Sung‐Min Won, Jin‐Ju Jeong, Dong Joon Kim, Ki‐Tae Suk

“…As the most stable conformers, IL6‐equol complex was attributed to GM, and PPAR alpha‐linoleic acid, PPAR delta‐stearic acid, and fatty acid–binding protein 4‐dimethyl 2,3‐bis(1,3‐dimethylindol‐2‐yl) fumarate complex were attributed to CKF. …”
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Overexpression of the microtubule-binding protein CLIP-170 induces a +TIP network superstructure consistent with a biomolecular condensate. by Yueh-Fu O Wu, Annamarie T Bryant, Nora T Nelson, Alexander G Madey, Gail F Fernandes, Holly V Goodson

“…Moreover, bioinformatic studies demonstrate that the presence of intrinsically disordered regions is conserved in key +TIPs, implying that these regions are functionally significant. Together, these results indicate that the CLIP-170 induced patches in cells are phase-separated liquid condensates and raise the possibility that the endogenous +TIP network might form a liquid droplet at MT ends or other +TIP locations.…”
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3D echocardiography derived reference values and determinants of left ventricular twist and torsion from the population-based STAAB cohort study by Julia Napp, Götz Gelbrich, Floran Sahiti, Vladimir Cejka, Dora Pelin, Lena Schmidbauer, Mengmeng Chen, Niklas Hitschrich, Marcus Schreckenberg, Stefan Frantz, Peter U. Heuschmann, Stefan Störk, Caroline Morbach

“…LV rotation is determined by a complex interplay of sub-endocardial and sub-epicardial fibers which might be affected differentially by potential risk factors. …”
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Dendritic overgrowth and elevated ERK signaling during neonatal development in a mouse model of autism. by Ning Cheng, Fawaz Alshammari, Elizabeth Hughes, Maryam Khanbabaei, Jong M Rho

“…Since dendritic structure is critical for information integration and relay, our data suggest that altered development of dendrites could potentially contribute to impaired hippocampal function and behavior observed in the BTBR model, and that this might be related to increased activation of the ERK pathway.…”
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Feedback driven autonomous cycles of assembly and disassembly from minimal building blocks by Antara Reja, Sangam Jha, Ashley Sreejan, Sumit Pal, Subhajit Bal, Chetan Gadgil, Dibyendu Das

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The role of molecular biomarkers in the diagnosis, prognosis, and treatment stratification of oral squamous cell carcinoma: A comprehensive review by Saravanan Ravindran, Srinivasan Ranganathan, Karthikeyan R, Nandini J, Shanmugarathinam A, Senthil Kumar Kannan, Durga Prasad K, Jalaiah Marri, Rajaganapathi K

“…Complex genetic mutations, epigenetic changes, and dysregulated signalling pathways are all part of the aetiology of OSCC. …”
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Modulation of Cardiac Contractility – a New Method in the Treatment of Heart Failure by A. A. Petrukhina, S. N. Tereshchenko, I. V. Zhirov

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