Resolving structural variability in network models and the brain. by Florian Klimm, Danielle S Bassett, Jean M Carlson, Peter J Mucha

“…Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. …”
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ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics. by Jamie S Lin, Jin Seok Jeon, Qingfeng Fan, Hetty N Wong, Matthew B Palmer, Lawrence B Holzman

“…In the nephrotoxic serum nephritis model, which induced immune-complex mediated injury, ARF6_PodKO mice exhibited aggravated proteinuria. …”
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Military experience predicts military multitasking better than laboratory measures in officer cadets by Yannik Hilla, Maximilian Stefani, Elisabeth V. C. Friedrich, Wolfgang Mack

“…We discuss the role of learned task representations in this regard and conclude that it might be more reasonable to investigate cognitive functions as co-variates of associations between military characteristics (e.g., military service duration) and military performance in future research than to focus on laboratory measures as predictors of military performance.…”
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Proteolysis of the human DNA polymerase delta smallest subunit p12 by μ-calpain in calcium-triggered apoptotic HeLa cells. by Xiaoting Fan, Qian Zhang, Chao You, Yuanxia Qian, Jing Gao, Peng Liu, Huiqing Chen, Huifang Song, Yan Chen, Keping Chen, Yajing Zhou

“…In vitro pull down and co-immunoprecipitation assays show that the μ-calpain binds to p12 through the interaction of μ-calpain with Pol δ other three subunits, not p12 itself, and PCNA, implying that the proteolysis of p12 by μ-calpain might be through a Pol δ4/PCNA complex. The p12 cleavage sites by μ-calpain are further determined as the location within a 16-amino acids peptide 28-43 by in vitro cleavage assays. …”
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Research progress of chondroitin sulfate and chondroitin sulfate proteoglycan in diabetic kidney disease by ZHANG Min, HU Chun, WU Xiao-yan

“…Chondroitin sulfate/chondroitin sulfate proteoglycan(CS/CSPG) is an essential component of ECM, including a large family of biological active molecules with complex structures and various functions. They play important functional and regulatory roles in physiology and pathology. …”
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Integrating proteomic and phosphoproteomic profiles provide new insights into ABA-dependent signal regulation network in maize response to heat stress by Yanpei Liu, Yulong Zhao, Haiying Zhan, Shanshan Lv, Yanmin Luo, Wei Wang, Xiuli Hu

“…Among them, heat shock proteins (17 DEPs and 3 DEPPs), transcription factors (9 DEPs and 27 DEPPs), ubiquitin-proteasome system components (1 DEP and 6 DEPPs), translation-related to proteins (23 DEPs and 22 DEPPs) and defensive proteins (12 DEP and 24 DEPPs) were identified, indicating that chaperon protein function, protein turnover, and defense system might be the key ABA-mediated processes in maize HS response. …”
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C5aR2 Deficiency Lessens C5aR1 Distribution and Expression in Neutrophils and Macrophages by Ting Zhang, Ning Ma, Jiaxing Wang, Xiaoyun Min, Linlin Wei, Ke Li

“…Our article found C5aR2 deficiency lessened C5aR1 distribution and expression in neutrophils and macrophages with different functions, indicating C5aR2 might function differently in different cells.…”
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Neural Networks vs. Regression: A Comparative Analysis in Medical Data Processing by Minodora ANDOR, Gheorghe Ioan MIHALAŞ

“…Regression provided robust results with minimal computational effort, while FFNN required complex tuning without a clear performance advantage. …”
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Public and patient involvement (PPI) in the design, execution and dissemination of a trial: the BISTRO trial by David Coyle, Paula Ormandy, Nancy Fernandes da Silva, Simon Davies

“…Background For people receiving haemodialysis, a balance has to be struck between removing sufficient but not too much fluid during a treatment session and maintaining any remaining kidney function they might have. In the BISTRO trial, this study sought to establish if getting the balance right might be improved by the additional use of bioimpedance, a device that measures body fluid composition to help decide how much fluid to remove during dialysis. …”
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Bacterial wilt resistance gene Slmlo1/6 mutants in tomato created by CRISPR/Cas9 technology by SHI Jianlei1, 2, XIONG Zili1, SU Shiwen1, FU Cunnian1, ZAI Wenshan1*

“…The pathogenic species are complex and tend to have a variation, while mlo caused by the recessive mutation of MLO genes has a broad-spectrum resistance. …”
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High‐order combination effects and biological robustness by Joseph Lehár, Andrew Krueger, Grant Zimmermann, Alexis Borisy

“…Biological systems are also complex, being organized into many functional modules that communicate through interlocking pathways and feedback mechanisms. …”
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Metal oxides on the frontlines: Antimicrobial activity in plant-derived biometallic nanoparticles by Krishnan Anbarasu, Sathishkumar Kuppusamy, Devi Okram Ricky, Agrawal Smita, Debnath Abhijit, Arasu Mariadhas Valan, Sundaram Thanigaivel, Subramanian Kumaran, Karunakaran Rohini

“…The work carefully evaluates the processes behind this dual function, providing insight into the complex interactions between metal oxides and chemicals originating from plants. …”
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Resilience of striatal synaptic plasticity over early structural adaptations in premotor parkinsonism by Leyre Merino-Galán, Marta Zamarbide, Arantzazu Belloso-Iguerategui, Marta C. Alonso-Moreno, Belén Gago, Alejandro Reinares-Sebastián, Javier Blesa, Dani Dumitriu, Ana Quiroga-Varela, María Cruz Rodríguez-Oroz

“…In conclusion, impaired striatal dopaminergic neurotransmisson diminishes striatal synaptic plasticity, which can be partially restored through complex structural changes in striatal spines. These adaptations might represent fundamental homeostatic mechanisms regulating synaptic function during the premotor stage of Parkinson’s disease.…”
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Renal Artery Blood Flow and Surface Parenchymal Perfusion During Renal Artery Endoshunting in a Porcine Model by Johan Millinger, Marcus Langenskiöld, Andreas Nygren, Klas Österberg, Joakim Nordanstig

“…This suggests that endoshunting to the kidney using an endoshunt system might be a promising strategy to preserve renal function when temporary interruption of native renal artery blood flow is needed during complex vascular surgical repairs involving the renal arteries.…”
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A fungal ubiquitin ligase and arrestin binding partner contribute to pathogenesis and survival during cellular stress by Lukas M. du Plooy, Calla L. Telzrow, Connie B. Nichols, Corinna Probst, Natalia Castro-Lopez, Floyd L. Wormley, J. Andrew Alspaugh

“…We identified a complex of proteins responsible for adding ubiquitin groups to fungal proteins, and this complex is required for virulence. …”
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Evaluating the Potential Use of Wearable Fitness Devices as a Measure of Outcomes in Orthopaedics by Jordan Henderson BS, Santiago Logan-Baca BS, Sara Kisiel BS, Fadi Muheidat PhD, David Jaffe MD

“…Despite objective measurements of activity consistency, patient-reported scores on factors like daily living and sport were nuanced, underscoring the complex interplay between physical functioning and subjective experience of pain. …”
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Diagnosis and management of a giant retroperitoneal hematoma compressing the femoral nerve, following an ultrasound-guided lumbar sympathetic block: a case report by Yan Bai, Xinqiao Zhou, Lingqing Zeng, Xiaokai Zhou, Zhuqing Rao, Cunming Liu, Yinbing Pan, Xiaodi Sun

“…Abstract Background The lumbar sympathetic nerve block stands as a pivotal approach in managing complex regional pain syndrome (CRPS) in the lower limbs. …”
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Chronic active Epstein–Barr Virus infection in a teenage girl with suspect autoimmune Hepatitis by Wen-Yu Tseng, Shiu-Feng Huang, Chao-Yi Wu, Shih-Hsiang Chen, Chien-Chang Chen

“…Abstract Background The pathogenesis of chronic active Epstein–Barr virus (EBV) disease (CAEBV) is complex, involving infection, inflammation, and in some cases malignancy. …”
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Optimizing dsRNA sequences for RNAi in pest control and research with the dsRIP web platform by Doga Cedden, Gözde Güney, Michael Rostás, Gregor Bucher

“…Abstract Background RNA interference (RNAi) is a tool for studying gene function and has emerged as a promising eco-friendly alternative to chemical pesticides. …”
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Sex-specific and opposite modulatory aspects revealed by PPI network and pathway analysis of ischemic stroke in humans. by Yan Lv, X Y He, Dongguo Li, Tao Liu, G Q Wen, Junfa Li

“…Gene Ontology (GO) functional annotation, Protein-Protein Interaction (PPI) network, "Molecular Complex Detection" (MCODE) modules, CytoNCA (cytoscape network centrality analysis) essential genes and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway interrelation analysis were performed.…”
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