Oral Sulforaphane Intervention Protects Against Diabetic Cardiomyopathy in db/db Mice: Focus on Cardiac Lipotoxicity and Substrate Metabolism by Pan Wang, Ziling Wang, Xinyuan Jin, Mengdi Zhang, Mengfan Shen, Dan Li

“…These results suggest that chronic oral SFN-I protects against DCM by mitigating overall metabolic dysregulation and inhibiting cardiolipotoxicity. The latter might involve controlling cardiac fatty acid metabolism and improving mitochondrial function, rather than promoting glucose metabolism.…”
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Dissecting the endothelial cell landscape in meningioma: single-cell insights into PLVAP+ subpopulations and their role in tumor angiogenesis by Liang Zhao, Hongling Jia, Zhikai Xiahou, Li Ren, Yanbing Song, Hao Xu, Zhihan Wang, Jin Xing

“…Although the majority of cases are benign, tumors located in complex anatomical regions or classified as atypical or malignant have a high recurrence rate, underscoring the need to optimize therapeutic strategies to improve patient outcomes. …”
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The difficult discussion on the deactivation of implantable cardioverter devices at the end of life: a systematic review by Siobhan C. Murray, Claire McNamara, Anna V. Chatzi

“…As clinicians' ethical considerations and fears emerged from the literature, nurses' special role has not been sufficiently supported. Complex care requires facilitation by multidisciplinary teams and education around the device's function regarding EOL issues. …”
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On the Analysis of the Contact Conditions in Temporomandibular Joint Prostheses by B. Gonzalez-Perez-Somarriba, G. Centeno, C. Vallellano, L. M. Gonzalez-Perez

“…Although temporomandibular joint replacements (TMJRs) are expected to accomplish their function during a number of years, they might actually fail and need to be replaced. …”
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Expression and distribution of activin-follistatin-inhibin axis in the urinary bladder by Weipu Mao, Tracy Zhang, Huan Chen, Sagar Barge, Zongwei Wang, Aria Olumi, Seth Alper, Weiqun Yu

“…The urothelial-localized ACVR2B/ACVR1B receptor complex suggests a role of activin signaling in urothelial function. …”
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Exercise in atherosclerosis: its beneficial effects and underlying mechanism by Meng-ting Yin, Meng-ting Yin, Meng-ting Yin, Meng-ting Yin, Liang Guo, Liang Guo, Liang Guo, Liang Guo

“…Atherosclerosis represents a complex interplay of inflammatory and metabolic processes, in which oxidative stress, endothelial inflammation, the phenotypic transition of smooth muscle cells (SMCs), and the conversion of macrophages into foam cells are involved. …”
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The double role of GABAergic system in systemic tumors: an updated review by Xueyang Yang, Qianhe Zu, Luxuan Wang, Chunhui Li, Lijian Zhang, Lijian Zhang

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Hybrid virtual screening and molecular dynamics approach for identification of allosteric modulator of EAAT2 by Chennu Manisha, Nagarjuna Palathoti, Jagdish Chand, Akey Krishna Swaroop, Jubie Selvaraj, B.R. Prashantha Kumar, Prisil Naveentha X, Brindha Durairaj, Antony Justin

“…Therefore, compounds that enhance EAAT2 function by reducing oxidative stress and excitotoxicity might be neuroprotective. …”
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A cell cycle timer for asymmetric spindle positioning. by Erin K McCarthy Campbell, Adam D Werts, Bob Goldstein

“…This mechanism involves the anaphase-promoting complex (APC), its activator Cdc20/Fizzy, its degradation target cyclin, and cyclin-dependent kinase (CDK). …”
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Combination of the ranking method and time reversal asymmetry for evaluating the quality of translations: a case study on passages from works by Edgar Allan Poe and Kenzaburo Oe by Kazuya Hayata

“…The complex systems approach to natural language has become a fascinating topic that is closely related to physics and linguistics. …”
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Inteligência biológica versus inteligência artificial: uma abordagem crítica Biologic intelligence versus artificial intelligence: a critical approach by Wilson Luiz Sanvito

“…In the present paper it is stressed that brain/mind complex constitutes a monolithic system that functions with emergent properties at several levels of hierarchical organization. …”
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QUALITY OF LIFE EVALUATION IN RECIPIENTS AFTER KIDNEY TRANSPLANTATION by E. P. Volynchik, M. M. Kaabak, I. I. Stenina, E. M. Balakirev, V. A. Goryainov

“…Obviously, quality of life of recipients with functioning transplanted kidney is undoubtedly of scientific interest and needs further extended studies that might contribute to better interpretation of long-term results after kidney transplantation.…”
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Single Nucleotide Polymorphisms in MicroRNA Binding Sites: Implications in Colorectal Cancer by Panchalee Bhaumik, Chandrasekhar Gopalakrishnan, Balu Kamaraj, Rituraj Purohit

“…Further we performed expression analysis to shed light on the potential tissues that might be affected by mutation, enrichment analysis to find the metabolic functions of the gene, and network analysis to highlight the important interactions of cancer causing genes with other genes to provide insight that complex network will be disturbed upon mutation. …”
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Membranoproliferative Glomerulonephritis and X-Linked Agammaglobulinemia: An Uncommon Association by Vasco Lavrador, Filipa Correia, Rita Sampaio, Cristina Cândido, Maria Sameiro-Faria, Laura Marques, Conceição Mota

“…He presented with pneumonia, macroscopic hematuria, nephrotic proteinuria, hypoalbuminemia, and hypercholesterolemia with normal renal function and serum complement levels. Renal histology showed immune complex mediated MPGN. …”
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Kanamycin and G-Quadruplexes: An Exploration of Binding Interactions by Gianmarco Gualtieri, Emanuele Liborio Citriniti, Roberta Rocca, Valentina Arciuolo, Jussara Amato, Antonio Randazzo, Stefano Alcaro

“…Modulating their stability and function holds promise for treating diseases like cancer. …”
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Exploring Basic Psychological Need Satisfaction and Relationship Quality as Protective Factors of Mental Well-Being During the COVID-19 Pandemic by Barbara Horvát, Tamás Martos, Claudia Chiarolanza, Viola Sallay, Ashley K. Randall

“…While better relationship experiences might even heighten perceived stress during a global crisis, they simultaneously function as protective factors for overall mental health.…”
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The Interaction among Microbiota, Immunity, and Genetic and Dietary Factors Is the Condicio Sine Qua Non Celiac Disease Can Develop by D. Pagliari, R. Urgesi, S. Frosali, M. E. Riccioni, E. E. Newton, R. Landolfi, F. Pandolfi, R. Cianci

“…Celiac disease (CD) is an immune-mediated enteropathy, triggered by dietary wheat gluten and similar proteins of barley and rye in genetically susceptible individuals. This is a complex disorder involving both environmental and immune-genetic factors. …”
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Comparative analyses of the gut microbiome of two sympatric rodent species, Myodes rufocanus and Apodemus peninsulae, in northeast China based on metagenome sequencing by Jing Cao, Shengze Wang, Ruobing Ding, Yijia Liu, Baodong Yuan

“…The gut microbiota of A. peninsulae and M. rufocanus differed marginally in functional profiles, specifically in the breakdown of complex carbohydrates, which might reflect their distinct food preferences albeit both being herbivores with a substantial dietary overlap. …”
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A neural circuit covarying with social hierarchy in macaques. by MaryAnn P Noonan, Jerome Sallet, Rogier B Mars, Franz X Neubert, Jill X O'Reilly, Jesper L Andersson, Anna S Mitchell, Andrew H Bell, Karla L Miller, Matthew F S Rushworth

“…To examine this possibility we used magnetic resonance imaging (MRI), which affords the taking of quantitative measurements noninvasively, both of brain structure and of brain function, across many regions simultaneously. We carried out a series of tests of structural and functional MRI (fMRI) data in 25 group-living macaques. …”
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Genome alteration of Leishmania orientalis under Amphotericin B inhibiting conditions. by Pornchai Anuntasomboon, Suradej Siripattanapipong, Sasimanas Unajak, Kiattawee Choowongkomon, Richard Burchmore, Saovanee Leelayoova, Mathirut Mungthin, Teerasak E-Kobon

“…The intricate interplay between SNPs and gene expression alterations might underscore the complex regulatory networks underlying the AmB resistance of L. orientalis strain PCM2.…”
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