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4901
Role of mass spectrometry-based serum proteomics signatures in predicting clinical outcomes and toxicity in patients with cancer treated with immunotherapy
Published 2022-03-01“…We discuss how these tests may inform patient prognosis as well as guide treatment decisions and predict irAE of immunotherapy. …”
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4902
Machine learning identifies PYGM as a macrophage polarization–linked metabolic biomarker in rectal cancer prognosis
Published 2025-08-01“…However, the metabolic and prognostic regulators governing this process remain largely undefined.MethodsWe constructed a macrophage polarization gene signature (MPGS) by integrating weighted gene co-expression network analysis (WGCNA) with multiple machine learning algorithms across two independent cohorts: 363 rectal cancer samples from GSE87211 and 177 samples from The Cancer Genome Atlas (TCGA). …”
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4903
Challenges, Difficulties, and Delayed Diagnosis of Multiple Myeloma
Published 2025-07-01“…Educational campaigns to raise awareness of the disease, algorithms dedicated to routine care and novel technologies, including AI and big data analytics, and new biomarkers may serve this purpose, as well as genomic approaches to the premalignant MGUS stage.…”
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4904
Prognostic significance of calcium-related genes in lung adenocarcinoma and the role of TNNC1 in macrophage polarization and erlotinib resistance
Published 2025-05-01“…Differences in immune infiltration and potential mechanisms in LUAD were explored using seven algorithms. The relationship between signature genes, chemotherapy sensitivity, and potential targeted therapies was evaluated. …”
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4905
Enhancing drinking water safety: Real-time prediction of trihalomethanes in a water distribution system using machine learning and multisensory technology
Published 2025-06-01“…Prolonged exposure to high concentrations of trihalomethanes (THMs) may generate human health risks due to their carcinogenic and mutagenic properties. …”
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4906
Among Artificial Intelligence/Machine Learning Methods, Automated Gradient-Boosting Models Accurately Score Intraoral Plaque in Non-Standardized Images
Published 2024-12-01“…Average and dominant hue, saturation, and brightness values were features for training plaque-scoring algorithms.Results Best performing models were: Support Vector Machine-Gaussian for image selection, 5-CV AUC-ROC of 0.99 and 0.76s of training time; Gradient-Boosting classification and regression models for individual teeth (5-CV AUC-ROC of 0.99 with 105s training); and mean plaque-scoring algorithms (5-CV R2 of 0.72 with 1415s training).Conclusions Accurate automated plaque-scoring is attainable without the high computational and financial costs of deep learning (DL) models. …”
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4907
Screening of endoplasmic reticulum stress characteristic genes and immune infiltration manifestations in chronic obstructive pulmonary disease
Published 2024-07-01“…Three machine learning algorithms, LASSO, SVM-RFE, and RF, were used to screen the characteristic genes, and their diagnostic performance was verified and evaluated in the GSE10006. …”
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4908
Machine learning to predict virological failure among HIV patients on antiretroviral therapy in the University of Gondar Comprehensive and Specialized Hospital, in Amhara Region, E...
Published 2023-04-01“…This study used different machine learning classification algorithms to predict the features that cause virological failure in HIV-positive patients. …”
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4909
Development and validation of an interpretable machine learning model for predicting left atrial thrombus or spontaneous echo contrast in non-valvular atrial fibrillation patients.
Published 2025-01-01“…The constructed logistic regression model, along with SHAP interpretation, may serve as a clinically useful tool for identifying high-risk NVAF patients. …”
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4910
Costs of testing sick children in primary care with pulse oximetry: Evidence from four countries, both with and without electronic clinical decision support.
Published 2025-01-01“…Adding clinical decision support algorithms (CDSA) can improve adherence to Integrated Management of Childhood Illness guidelines. …”
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4911
Exploration of shared pathogenic factors and causative genes in early-stage endometrial cancer and osteoarthritis
Published 2025-07-01“…Genes with diagnostic value were identified using multiple machine learning algorithms to construct EC prediction models and evaluate their performance. …”
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4912
The Application and Ethical Implication of Generative AI in Mental Health: Systematic Review
Published 2025-06-01“…However, to ensure ethical and effective implementation, comprehensive safeguards—particularly around privacy, algorithmic bias, and responsible user engagement—must be established.…”
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4913
Improving TMJ Diagnosis: A Deep Learning Approach for Detecting Mandibular Condyle Bone Changes
Published 2025-04-01“…The study utilizes a range of advanced deep learning algorithms, including Dense Networks, Residual Networks, VGG Networks, and Google Networks, which are pre-trained with transfer learning techniques. …”
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4914
Nutritional markers of undiagnosed type 2 diabetes in adults: Findings of a machine learning analysis with external validation and benchmarking.
Published 2021-01-01“…We tested three machine learning algorithms on original and resampled training datasets built using three resampling methods. …”
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4915
Assessing the effects of therapeutic combinations on SARS-CoV-2 infected patient outcomes: A big data approach.
Published 2023-01-01“…A big data approach to analyzing real-world impacts of therapies may confirm or supplement RCT evidence to further assess effectiveness of therapeutic options for rapidly evolving diseases such as COVID-19.…”
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4916
PREDICTION INTERVALS IN MACHINE LEARNING: RESIDUAL BOOTSTRAP AND QUANTILE REGRESSION FOR CASH FLOW ANALYSIS
Published 2025-07-01“…While point predictions are commonly used, they may not adequately capture this uncertainty, especially in financial systems where forecasting accuracy directly impacts decision-making. …”
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4917
Assessment of structural changes in the left atrium myocardium according to cardiac magnetic resonance with contrast before and after balloon cryoablation in patients with persiste...
Published 2023-05-01“…Magnetic resonance imaging of the heart with contrast allows to assess fibrotic lesion of the myocardium of left atrial, which may be one of the factors of the effectiveness of interventional treatment of persistent AF.…”
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4918
Evaluation of the performance of ERA5, ERA5-Land and MERRA-2 reanalysis to estimate snow depth over a mountainous semi-arid region in Iran
Published 2025-04-01“…Future research could benefit from integrating additional datasets and employing machine learning algorithms to improve snow depth assessments, as these approaches may reduce estimation uncertainties and enhance the understanding of snow dynamics across various regions, ultimately contributing to more reliable hydrological assessments.…”
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4919
Advancing mmWave Altimetry for Unmanned Aerial Systems: A Signal Processing Framework for Optimized Waveform Design
Published 2024-08-01“…Aptly, it is proposed that a mm-level accurate RA may be exploited as a software redundancy for the critical weight-on-wheels (WoW) system in fixed-wing commercial UASs. …”
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4920
Integrated Analysis of Ferroptosis- and Cellular Senescence-Related Biomarkers in Atherosclerosis Based on Machine Learning and Single-Cell Sequencing Data
Published 2025-07-01“…Eight machine learning algorithms were applied to identify hub genes and construct a diagnostic model. …”
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