Cost-effectiveness of different tuberculosis diagnostic approaches in Nigeria based on decision analytical modelling by Muktar H Aliyu, Hafsat U Ibrahim, Rayyan M Garba, Jameel I Ahmad, Kabiru Abdulsalam, Yasir N Jibril, Faisal S Dankishiya, Abdullahi Ibrahim, Ibrahim U Garzali, Aisha A Galadanci, Abdullahi K Suleiman, Abdulgafar L Olawumi, Umar F Abdullahi, Fatima M Mahmud, Amina A Umar, Olive Asafu- Adjaye, Lukman F Owolabi, Baba M Musa

“…However, the Xpert MTB/RIF Ultra may provide additional value in settings with sufficient infrastructure and funding. …”
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Massive Acquisition of Ultraviolet Color Excess Information from GALEX and UVOT Bands by Dongliang Yang, Mingxu Sun, Biwei Jiang, Wenyuan Cui, Ruoyi Zhang, Luyao Shi, Jiachen Wei

“…This suggests that a single-parameter R _V extinction law may not be sufficient to simultaneously characterize the extinction behavior across infrared, optical, and ultraviolet bands.…”
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Prognostic genes in colon cancer and their correlation with immune cells: an analysis based on bioinformatics by Gu Zhiwen, Wu Yinteng, Liao Cun, Ma Hui, Zhang Sen, Zhang Xiaolong

“…The prognosis-related genes were screened and their expression was verified by qPCR. Cibersort algorithm was used to analyze the correlation between prognostic genes and immune cells. …”
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Multiomics profiles of genome-wide alterations in H3K27ac in different lung lobes after acute graft-versus-host disease with MSCs treatment by Zixuan Lu, Yuming Zhou, Yuming Zhou, Chengyu Li, A. M. Abd El-Aty, A. M. Abd El-Aty, Chengxia Liu, Xiying Luan, Bin Wang, Guoyan Wang, Guoyan Wang

“…The subset with high expression levels of these genes tended to present anti-inflammatory effects and reduced cytotoxic activity. Our study may provide new insights into the development of potential therapeutic drugs that target H3K27ac to assist in MSC treatment.…”
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Evaluating the expected effects of disclosure of patient safety incidents using hypothetical cases in Korea. by Minsu Ock, Eun Young Choi, Min-Woo Jo, Sang-Il Lee

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Blocking the interaction between S100A9 protein and RAGE V domain using S100A12 protein. by Revansiddha Katte, Chin Yu

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The value of habitat analysis based on 18F-PSMA-1007 PET/CT images for prostate cancer risk grading by Yang Wang, Hongyue Zhao, Zhehao Lyu, Linhan Zhang, Wei Han, Zeyu Wang, Jiafu Wang, Xinyue Zhang, Shibo Guo, Peng Fu, Changjiu Zhao

“…The whole prostate was manually contoured on PET and CT images as the volume of interest (VOI). Using the Otsu algorithm, the VOI was divided into four habitat subregions. …”
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Integrative bioinformatics analysis of pyroptosis-related genes and immune infiltration patterns in childhood asthma by Di Lian, Chenye Lin, Meiling Xie, JianXing Wei, Xueling Huang, Ke Lian, Qiuyu Tang

“…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses showed that PRDEGs were primarily enriched in biological processes related to the immune response, cell disassembly, and inflammatory pathways.ResultsImmune cell infiltration analysis using the CIBERSORT algorithm revealed significant differences between the CA and control groups, with increased macrophages M0, activated mast cells, and γδ T cells and decreased resting natural killer cells in the CA group. …”
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Assessing tafenoquine implementation in Brazil: a qualitative evaluation of perceptions of healthcare providers and Plasmodium vivax patients (QualiTRuST Study) by Alicia P. C. Santos, Marcelo A. M. Brito, Ana P. S. Oliveira, Rafaela N. Dávila, Hiran S. S. Gama, Evellyn A. R. T. Silva, Hélio A. Amazonas Jr., Patrícia C. S. Balieiro, Rosilene Rufatto, Penny Grewal Daumerie, Cássio R. L. Peterka, Dhélio Batista Pereira, Marcus V. G. Lacerda, Felipe L. G. Murta

“…Positive perceptions of the medication may aid in improving patient adherence to malaria treatment, thereby reducing malaria recurrences. …”
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Allosteric binding sites in Rab11 for potential drug candidates. by Ammu Prasanna Kumar, Suryani Lukman

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The use of informal care by people with vision impairment. by Ana Patricia Marques, Antonio Filipe Macedo, Laura Hernandez-Moreno, Pedro Lima Ramos, Thomas Butt, Gary Rubin, Rui Santana, Portuguese visual impairment study group (PORVIS-group)

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Calcium and cAMP directly modulate the speed of the Drosophila circadian clock. by Angelina Palacios-Muñoz, John Ewer

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Modelling the effect of bednet coverage on malaria transmission in South Sudan. by Abdulaziz Y A Mukhtar, Justin B Munyakazi, Rachid Ouifki, Allan E Clark

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Modeling circadian variability of core-clock and clock-controlled genes in four tissues of the rat. by Panteleimon D Mavroudis, Debra C DuBois, Richard R Almon, William J Jusko

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Analysis of factors influencing clinical pregnancy rates in frozen-thawed embryo transfer cycles by Junqiang Wang, Zexing Yang, Ying Chen, Ying Chen, Fengchen Gao, Wenxiu Zhao, Shuxuan Cao, Yixi Li, Limei He, Limei He

“…Baseline characteristics were compared between groups. A random forest algorithm was applied to rank the importance of variables, followed by dimensionality reduction using a sliding window sequential forward selection (SWSFS) method. …”
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The Fetal Region-specific Optimized Growth Standard (FROGS)-A fetal and birthweight centile calculator validated in a national population. by Natasha L Pritchard, Stephen Tong, Teresa MacDonald, Elizabeth McCarthy, Lisa Hui, Michael Bethune, Hannah G Gordon, Roxanne Hastie, Emerson Keenan, Michael Permezel, Susan P Walker, Anthea C Lindquist

“…This study is limited in that it retrospectively assesses birthweight, which may have different implications to a prospective evaluation of estimated fetal weight.…”
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Age and sex specific thresholds for risk stratification of cardiovascular disease and clinical decision making: prospective open cohort study by Matthew Sperrin, Angela M Wood, Lois Kim, Zhe Xu, Emanuele Di Angelantonio, Stephen Kaptoge, Juliet Usher-Smith, Matthew Arnold, Lisa Pennells, Ryan Chung

“…Objective To quantify the potential advantages of using 10 year risk prediction models for cardiovascular disease, in combination with risk thresholds specific to both age and sex, to identify individuals at high risk of cardiovascular disease for allocation of statin treatment.Design Prospective open cohort study.Setting Primary care data from the UK Clinical Practice Research Datalink GOLD, linked with hospital admissions from Hospital Episode Statistics and national mortality records from the Office for National Statistics in England, 1 January 2006 to 31 May 2019.Participants 1 046 736 individuals (aged 40-85 years) with no cardiovascular disease, diabetes, or a history of statin treatment at baseline using data from electronic health records.Main outcome measures 10 year risk of cardiovascular disease, calculated with version 2 of the QRISK cardiovascular disease risk algorithm (QRISK2), with two main strategies to identify individuals at high risk: in strategy A, estimated risk was a fixed cut-off value of ≥10% (ie, as per the UK National Institute for Health and Care Excellence guidelines); in strategy B, estimated risk was ≥10% or ≥90th centile of age and sex specific risk distributions.Results Compared with strategy A, strategy B stratified 20 241 (149.8%) more women aged ≤53 years and 9832 (150.2%) more men aged ≤47 years as having a high risk of cardiovascular disease; for all other ages the strategies were the same. …”
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Application of Intravoxel Incoherent Motion in the Prediction of Intra-Tumoral Tertiary Lymphoid Structures in Hepatocellular Carcinoma by Ma L, Liao S, Zhang X, Zhou F, Geng Z, Hu J, Zhang Y, Zhang C, Meng T, Wang S, Xie C

“…The logistic regression algorithm was used to construct the prediction model based on the combination of these features. …”
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Prediction of lung overdistension during mechanical ventilation using micro-RNA and gene expression by Cecilia López-Martínez, Paula Martín-Vicente, Laura Amado-Rodríguez, Inés López-Alonso, Margarita Fernández-Rodríguez, Adrián González-López, Pablo Martínez-Camblor, Juan Gómez, Andrew J. Boyle, Cecilia M. O’Kane, Daniel F. McAuley, James N. Tsoporis, Claudia dos Santos, Guillermo M. Albaiceta

“…Abstract Background Overstretching of lung parenchyma may lead to injury, especially during mechanical ventilation. …”
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Notch signaling and taxis mechanisms regulate early stage angiogenesis: A mathematical and computational model. by Rocío Vega, Manuel Carretero, Rui D M Travasso, Luis L Bonilla

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