Clinical Effectiveness of Tislelizumab With Gemcitabine/Cisplatin Versus Gemcitabine/Cisplatin Alone as Adjuvant Therapy for High‐Risk Muscle‐Invasive Urothelial Carcinoma: A Real‐... by Yanjun Wang, Kaihua Zhong, Xingliang Tan, Qianghua Zhou, Lijuan Jiang, Kai Yao, Zhiming Wu

“…Both groups experienced manageable grade 1–2 immune‐related AEs, with pruritus being the most common, followed by liver function abnormalities and thyroid disturbances. Nonhematologic toxicities in the Tisle+GC group included elevated aspartate aminotransferase and hyponatremia, while the GC group mainly reported vomiting. …”
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Targeted Dual‐Responsive Liposomes Co‐Deliver Jolkinolide B and Ce6 to Synergistically Enhance the Photodynamic/Immunotherapy Efficacy in Gastric Cancer through the PANoptosis Path... by Chenhui Ma, Lei Gao, Kewei Song, Baohong Gu, Bofang Wang, Yang Yu, Xueyan Wang, Xuemei Li, Jike Hu, Weigao Pu, Yunpeng Wang, Na Wang, Dedai Lu, Zhijian Han, Hao Chen

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Ovarian Reserve: A Critical Indicator of Female Reproductive Health by Julia Ufnal, Anna Wolff, Maria Morawska, Dominika Lewandowska, Dominika Rosińska-Lewandoska, Marcelina Szewczyk, Klaudia Kożuchowska, Dawid Pilarz, Kinga Jarosz, Szymon Gruszka

“…Factors such as obesity, thyroid dysfunction and endometriosis significantly impact ovarian reserve. …”
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Association of vitamin D deficiency and insufficiency with uncontrolled type 1 diabetes Mellitus among Saudi pediatric patients; a hospital-based retrospective study by Salman Almansour, Abdullrahman Alsalamah, Mohammad Almutlaq, Ahmed Sheikh, Hamdan Z. Hamdan, Abdullah Al-Nafeesah, Ashwaq AlEed, Ishag Adam, Osama Al-Wutayd

“…Their 25(OH)D levels and thyroid function were measured using standard methods.ResultsOf the 218 children in this study, 182 (83.5%) had uncontrolled T1DM, while only 36 (16.5%) had controlled T1DM. …”
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Acute neuroendocrine changes after traumatic brain injury by Zsofia Dina Magyar-Sumegi, Levente Stankovics, Dominika Lendvai-Emmert, Andras Czigler, Emoke Hegedus, Mark Csendes, Luca Toth, Zoltan Ungvari, Andras Buki, Peter Toth

“…Adrenal insufficiency (AI) was present in 10% of TBI patients (prevalence can be as high as 50% after severe TBI), and hypocortisolemia is a predictor of mortality and long-term hypopituitarism. Suppression of the thyroid axis in 2–33% of TBI patients may be an independent predictor of adverse neurological outcome, as well. 9–36% of patients with severe TBI exhibit decreased function of the somatotrophic axis with a divergent effect on the central nervous system. …”
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Change in Pattern of Head and Neck Lesions Diagnosed by FNAC in the Post-COVID-19 Period: Are Lymphoproliferative Disorders on the Rise? by Shiv Kumar, Shilpi Saxena, Anubhav Singh, Kamal Deep Joshi, Mirza Saleem Amjad, Vidushi Joshi, Abhinav Bhardwaj

“…Introduction: Coronavirus disease 2019 (COVID-19) infection is associated with a variety of immune dysregulations. Aberrant immune function can lead to a plethora of lymphoproliferative and autoimmune dysfunctions. …”
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Immunological testing for female infertility: a modern view on the problem by A. V. Konkina, L. A. Blikyan, D. E. Aleynikova, I. R. Abubakarov, A. S.-M. Dzhumanyazova, A. V. Abramian, L. G. Gafurova, D. A. Lobko, A. A. Pozoyan, K. M. Thagapsova, M. S. Golubeva, E. E. Shvanova, E. O. Ryzhov

“…It has been suggested that antinuclear antibodies (ANA) may affect reproductive function by disrupting trophoblast cell development and interfering with RNA transcription, which may lead to lowered reproductive success. …”
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The Association Between Uterine Artery Pulsatility Index at Mid-Gestation and the Method of Conception: A Cohort Study by Antonios Siargkas, Ioannis Tsakiridis, Dimitra Kappou, Apostolos Mamopoulos, Ioannis Papastefanou, Themistoklis Dagklis

“…Uterine artery Doppler pulsatility index (UtA-PI) reflects placental function. This study aimed to examine whether second-trimester UtA-PI differs according to the conception method after adjusting for potential confounding factors. …”
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INTERACTION BETWEEN DENTO-MAXILLOFACIAL ANOMALIES AND GENERAL-SOMATIC HUMAN CONDITION (LITERATURE REVIEW) by L.V. Smaglyuk, H.V. Voronkova, A.Ye. Karasiunok, A.V. Liakhovska, V.I. Smaglyuk

“…The skeletal pathology of the Angle I class, as well as impaired functional state of the TMJ were diagnosed. Thyroid hormone and thyroxin stimulates growth in the sphenoid-occipital synchondrosis, nasal cartilage and the growth of the upper jaw in the area of bone sutures, thereby determining of the size and position of the upper jaw. …”
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Polymorphic loci of the <i>ESR1<i/> gene are associated with the risk of developing preeclampsia with fetal growth retardation by O. V. Golovchenko, M. Yu. Abramova, I. V. Ponomarenko, M. I. Churnosov

“…Polymorphic locirs2234693, rs9340799 ESR1 gene and rs3798577 have an important functional significance in human body being located in the evolutionarily conserved DNA region, affect affinity of regulatory DNA motifs to the eight transcription factors as well as ESR1 gene expression in the thyroid gland, which are positioned in the promoter and enhancer region, DNAse 1 hypersensitivity motif within diverse organs and tissues, and display an important pathogenetic effect for development of PE and FGR. …”
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<i>MTRR</i> gene rs1801394 polymorphism is associated with neonatal birth weight in pregnant women with fetal growth retardation by Yu. N. Reshetnikova, I. V. Ponomarenko, V. М. Churnosov, M. S. Ponomarenko, M. I. Churnosov, E. A. Reshetnikov

“…Aim: to assess associations between folate cycle gene polymorphism and neonatal birth weight in pregnant women with fetal growth retardation (FGR) and related functional effects in population of the Central Black Earth Region.Materials and Methods. 98 cases of women with FGR were enrolled to a retrospective molecular and genetic screening to assess prevalence 5 SNPs (single nucleotide polymorphisms) in genes involved in folic acid cycle and methionine metabolism (rs699517 TYMS, rs2790 TYMS, rs1979277 SHMT1, rs1805087 MTR, rs1801394 MTRR).Results. …”
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Monitoring the effectiveness of the natural anticoagulant sulodexide in pregnant women with autoimmune hyperthyroidism on the background of hyperhomocysteinemia by A.Yu. Scherbakov, Т. А. Mіelikova

“…Among the factors that affect hemostasis, thyroid hormones occupy a special place, they are able to influence not only the functional activity of platelets, but also adjust the intensity of the plasma and tissue fibrinolysis. …”
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Characteristics of Bone System Condition in Children from Clean and Polluted Regions by Indexes of Ultrasound Densitometry by Kech N.

“…In the opinion of scientists, the thyroid gland occupies the first place by the degree of sensitivity to the action of the negative influence of xenobiotics in a child’s organism then – the liver, lungs, kidneys and bone system. …”
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Clinical and diagnostic manifestations in women of reproductive age having both hyperthyroidism and hyperandrogenism by N. E. Akhundova

“…Aim: to study the clinical and diagnostic manifestations of hyperandrogenism (HA) in women with subclinical thyrotoxicosis.Materials and methods. Sixty three hyperthyroid women with clinical manifestations of HA were examined. …”
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EXTRAOSSEOUS ABNORMALITIES AND ARTIFACTS IN SKELETAL SCINTIGRAPHY by S. P. Mironov, A. A. Ansheles, D. N. Shulgin, V. B. Sergienko

“…First category included anatomical and functional changes in the urinary system (kidney location anomalies and nonobstructive uropathies). …”
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Clinical-pathagenetic, Age, Gender, Genetic Aspects of Non-alcoholic Fatty Liver Disease and Nonviral Chronic Hepatitis Without, and also with Comorbid Hypothyroidism; Improving of... by Prysyazhnyuk V., Voloshyn O.

“…Caro index was determined, and in patients with manifested hypothyroidism the growth of HOMA IR index comparable to respective indicators in NAFLD patients with normal thyroid function was found. On the basis of the obtained data, the treatment process was improved by L-carnitine added to basic therapy in NAFLD and CH patients, resulting in more effective decrease in the activity of cytolytic and cholestatic syndromes markers, decrease of tumor necrosis factor-a content, as manifestations of reducing inflammation processes intensity. …”
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The Modulation of Fibrosis in Vocal Fold Repair: A Study on c-Met Agonistic Antibodies and Hepatocyte Growth in Animal Studies by Hyun-Il Shin, Hyunsu Choi, Jae-Kyun Jung, Choung-Soo Kim

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Decoding the role of serum cholinesterase among type 2 diabetes mellitus patients at RIMS, Ranchi – A hospital-based study by Avijit Saha, Abha Kumari, Santosh Kumar, Abhay Kumar, Chandrakanta Munni

“…Blood samples are collected from all participants to measure serum cholinesterase levels; FBS, PPBS, HbA1c, serum urea, creatinine, lipid profile, thyroid profile, liver function tests (total bilirubin, direct bilirubin, AST, ALT, alkaline phosphatase), and urine protein creatinine ratio are assessed. …”
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Altered static and dynamic spontaneous brain activity in patients with dysthyroid optic neuropathy: a resting-state fMRI study by Jinling Lu, Hao Hu, Jiang Zhou, Wenhao Jiang, Xiongying Pu, Huanhuan Chen, Xiaoquan Xu, Feiyun Wu

“…PurposeTo investigate static and dynamic brain functional alterations in dysthyroid optic neuropathy (DON) using resting-state functional MRI (rs-fMRI) with the amplitude of low-frequency fluctuation (ALFF) and regional homogeneity (ReHo).Materials and methodsFifty-seven thyroid-associated ophthalmopathy (TAO) patients (23 DON and 34 non-DON) and 27 healthy controls (HCs) underwent rs-fMRI scans. …”
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Impact of Hyperbaric Oxygenation on Ammonia Kinetics in Hepatic Failure (an Experimental Study) by P. N. Savilov, D.V. Molchanov, A. A. Alabovsky

“…At the same time HBO induces short-term activation of ammoniogenesis in thyroid and cardiac tissues, which should be considered as a sign of their enhanced functional activity. …”
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