A multi-view CNN model to predict resolving of new lung nodules on follow-up low-dose chest CT by Jingxuan Wang, Xiaowen Zhang, Wei Tang, Marcel van Tuinen, Rozemarijn Vliegenthart, Peter van Ooijen

“…We evaluated the performance of a multi-view convolutional neural network (CNN) in distinguishing resolving and non-resolving new, intermediate-sized lung nodules. Materials and methods This retrospective study utilized data on 344 intermediate-sized nodules (50–500 mm3) in 250 participants from the NELSON (Dutch-Belgian Randomized Lung Cancer Screening) trial. …”
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Clinical evaluation of the implementation of the first pilot Russian integrated program for an integrated approach to the management of diabetes mellitus “NORMA” by G. R. Galstyan, A. Y. Mayorov, O. G. Melnikova, N. I. Holmskaya, Z. A. Hamradjanov, V. I. Milyutin, M. V. Shestakova

“…In this regard, the search for new integrated solutions that could strengthen disease control and improve clinical outcomes becomes relevant.AIM: To assess the impact of the developed integrated approach to disease management on the clinical and metabolic outcomes of patients with type 1 (T1DM) and type 2 diabetes mellitus (T2DM) participating in the “NORMA” pilot program for 3 and 6 months.MATERIALS AND METHODS: “NORMA” is the first Russian program designed to implement an integrated approach to DM management combines structured online education, blood glucose monitoring, supervision by endocrinologist, and administrative support. …”
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The use of biological disease-modifying antirheumatic drugs and Janus kinase inhibitors in rheumatoid arthritis during the COVID-19 coronavirus disease pandemic: data from a teleph... by A. E. Karateev, E. Yu. Polishchuk, A. S. Potapova, E. V. Matyanova, A. S. Semashko, А. O. Bobkova, E. S. Filatova, V. N. Amirjanova, S. I. Glukhova, E. G. Zotkin, A. M. Lila

“…The prescribing of biological disease-modifying antirheumatic drugs (bDMARDs) and Janus kinase inhibitors (iJAK) during the COVID-19 pandemic requires a balanced approach and tight monitoring of the patients.The aim of the study was to study the effect of bDMARDs and iJAK inhibitors on the condition of patients with rheumatoid arthritis (RA), taking the patients reported outcomes, as well as the incidence of COVID-19 in these patients.Materials and methods. A telephone survey was conducted of 254 patients with RA (average age – 49.8±13.7 years; 64.4% of patients are positive for rheumatoid factor; women – 83.5%; DAS28 score – 5.4±1.6 points), who in the period from January 2020 to June 2021 were prescribed bDMARDs or iJAK for the first time: 148 (58.3%) – rituximab; 57 (22.4%) – tumor necrosis factor α inhibitors; 20 (7.9%) – iJAK; 17 (6.7%) – interleukin 6 inhibitors; 12 (4.7%) – abatacept.Results. …”
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Efficacy of Levobupivacaine versus Ropivacaine for Tonsillar Pillar Block in Patients Undergoing Tonsillectomy: A Randomised Clinical Trial by Vishnu Sadanandan, Antony John Charles, Srinivasan Parthasarathy

“…Aim: To compare levobupivacaine and ropivacaine for posttonsillectomy analgesia. Materials and Methods: This hospital-based randomised double-blinded clinical trial was conducted at Mahatma Gandhi Medical College and Research Institute, Puducherry, India, between March 2023 and February 2024 on 60 American Society of Anaesthesiologists (ASA) physical status Class I and II patients aged between 7 and 25 years undergoing elective tonsillectomy under general anaesthesia. …”
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Differentiated approach in the treatment of diffuse large B-cell lymphoma according to c-MYC and BCL2 status by R. K. Karakulov, D. R. Kaydarova, Z. D. Dushimova, S. T. Gabbasova, G. A. Sagindykov, B. A. Nasipov, A. S. Dzhazyltaeva, N. A. Kemelbekov

“…Nevertheless, the clinical features of this subgroup of DLBCL remain poorly understood.The objective of the study was to analyze the incidence of c-MYC gene aberrations, BCL2 expression in DLBCL patients and to evaluate the effectiveness of intensive R + Hyper-CVAD chemotherapy regimen in this group of patients.Materials and methods. We analyzed the data of 80 patients aged 18–65 years with a newly diagnosed DLBCL for the period from 2018 to 2020. …”
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Time factors of clinical effectiveness of mechanical thrombectomy in acute ischemic stroke by A.M. Netliukh, A.A. Sukhanov

“…Objective ‒ to analyze the relationship between the severity of the patient’s condition at admission, delays before the start of thrombectomy and the influence of the time factor on the functional outcome at discharge. Materials and methods. Informed consent was obtained from each patient (parent or guardian) enrolled in the study and the study protocol conforms to the ethical guidelines of the Declaration of Helsinki as reflected in a priori approval by the Institutional Ethical Review Board (Institution's Human Research Committee). …”
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Provenance-Finding of Dust Storms Using AVHRR Sensor Images of NOAA Satellite (Case Study: Southwest of Iran) by Mohammad Hossein Rezaei Moghaddam, Mojtaba Mahdian Boruojeni

“…The present study aims at identifying the origin and dust removal centers located in the southwest of Iran's borders. 2- Materials and Methods In this study, investigating the dust of the southwest of Iran, AVHRR sensor of NOAA satellite have been used to identify the origins of dust storms. …”
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The role of visceral hypersensitivity and cortisol levels in the development of intestinal dysfunction in coexisting hypothyroidism by V. H. Mishchuk, H. V. Kozinchuk, O. Z. Venhrovych, U. P. Shalamai

“…The aim is to study the role of visceral hypersensitivity and cortisol levels in patients with intestinal dysfunction in coexisting hypothyroidism and in those with constipation or diarrhea without thyroid dysfunction. Materials and methods. A total of 41 patients with hypothyroidism were examined, of whom 24 were diagnosed with persistent constipation and 17 with diarrhea, along with 36 patients with irritable bowel syndrome (IBS) (control group), of whom 22 had constipation and 14 had diarrhea. …”
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Intravital Position Study of the Clinical Anatomy of the Middle Lobe and Superior Poles of the Thyroid Gland by Vladislav V. Tatarkin, Andrey I. Shchegolev, Aleksandr M. Bakunov, Yuriy L. Vasil’ev, Mikhail D. Chernyshev, Evgeniy A. Serebryakov, Ksenia L. Kaplieva, Egor O. Stetsik, Tahmina Pulotova, Ellina V. Velichko, Evgeniy M. Trunin

“…The purpose was to provide an intravital position study of the clinical anatomy of the middle and superior poles of the thyroid gland (TG). <i>Materials and Methods</i>: We used data on anthropometry obtained during the study and data from MRI of the neck organs and anatomical formations of 100 healthy individuals, comprising 55 (55%) female and 45 (45%) male participants. …”
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DETERMINATION OF THE QUALITY OF LIFE OF PATIENTS WITH CONGENITAL CLEFT OF THE UPPER LIP AND PALATE BEFORE AND AFTER THEIR ORTHOPEDIC REHABILITATION by M. Y. Oliinyk

“…The aim of the study was to assess the life quality of patients with congenital malformations of the upper lip and palate before and after the final stage of orthopedic treatment with different types of aesthetic designs of dentures. Material and methods. An investigation of the life quality related to the oral health was proposed using data of 37 patients aged 17 to 36 years, including 26 men and 11 women with congenital malformations of the upper lip and palate, using the OHIP-14 (Oral health impact profile) questionnaire. …”
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RESULTS OF COMPREHENSIVE STUDIES OF THE UNDERGROUND HYDROSPHERE WITHIN THE WESTERN SHOULDER OF THE BAIKAL RIFT (AS EXEMPLIFIED BY THE BAYANDAI – KRESTOVSKY CAPE SITE) by Konstantin Zh. Seminsky, Marina A. Tugarina

“…The relationship between dislocations and watercut allows determining specific features of the zoneblock structure by regions by applying methods of hydrogeological surveys for studies of shallow horizons and geophysical methods, which are more sensitive to fluid contents, for studies of deeper layers. …”
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Comparative legal analysis of the labor law status of a higher school lecturer by T. F. Vysheslavova, S. A. Lukinova

“…At the same time, scientists pay very little attention to the issues of the social and labor status of a lecturer. Materials and Methods. The authors analyze the points of view expressed in science regarding problems related to the legal regulation of the work of a lecturer (the content and term of the employment contract, the structure of the labor function, remuneration, etc.), in the context of the peculiarities of the modern Russian state and law. …”
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ROLE OF SYNTAX SCORE SCALE IN THE STRATIFICATION OF THE NOSOCOMIAL RISK OF CARDIOVASCULAR COMPLICATIONS AND LETHALITY IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION by D. B. Nemik, G. V. Matyushin, S. A. Ustyugov

“…To study the impact of the assessment by angiographic SYNTAX Score scale on in-hospital complications and lethality in patients with STEMI.Material and methods. The single-center observational retrospective study was performed. …”
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Conservative or surgical treatment? Optimizing management strategies in medial hypertensive intracerebral hemorrhages by M.Ye. Polishchuk, A.A. Kaminskyi, A.A. Oblyvach, D.V. Shchehlov, O.M. Honcharuk, A.V. Muravskyi

“…Objective ‒ to determine the optimal treatment strategy for patients with medial hypertensive intracerebral hemorrhages (ICH) by comparing the effectiveness of conservative and surgical approaches. Materials and methods. A clinical study was conducted at the Kyiv Emergency City Clinical Hospital. …”
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Parameters of leukopoiesis and thrombocytopenia in early urosepsis as potential predictors of a lethal outcome in hospitalized patients by S. V. Fedosenko, Yu. O. Rodionova, A. I. Ivanova, M. B. Arzhanik, O. L. Semenova, S. V. Nesterovich, E. A. Starovoitova, A. P. Zima, D. A. Vinokurova, E. М. Kamaltynova, V. V. Kalyuzhin

“…To perform a comparative analysis of leukopoiesis parameters and platelet count in peripheral blood with evaluation of their changes in the first 48 hours from urosepsis (US) verification in hospitalized patients depending on the outcome of the disease.Materials and methods. A retrospective comparative study included 40 patients with US divided into a group of deceased (n = 10) and a group of recovered (n = 30) individuals. …”
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Comparatively analyzed quality of life in patients with atypical endometrial hyperplasia and endometrial cancer during various rehabilitation activities by L. N. Sandzhieva, A. G. Solopova, D. V. Blinov, V. N. Galkin, E. E. Achkasov

“…However, after ovariohysterectomy, young women develop postovariectomy syndrome (POES) and psychosexual disorders profoundly decreasing quality of life (QoL) that requires rehabilitation measures.Aim: to conduct a comparative analysis of QoL in patients with recurrent AEH after hysterectomy with bilateral salpingooophorectomy based on the management tactics in the rehabilitation period.Materials and Methods. In the second part of the prospective randomized comparative study, 58 women diagnosed with recurrent AEH (mean patient age 44.25 ± 3.40 years) underwent a one-year-follow-up, divided into 2 groups according to the management tactics in the rehabilitation period: group 1 – 27 patients with "active" rehabilitation according to the complex rehabilitation and therapeutic protocol proposed by our research group; group 2 – 31 patients with "passive" rehabilitation. …”
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Granulomatosis with polyangiitis under the guise of pulmonary tuberculosis: difficulties in diagnosis by E. I. Shmidt, M. R. Mazra, A. P. Raksha, A. N. Novikova, M. E. Dmitrieva, V. V. Azarovskaya

“…To present a clinical case of late diagnosis of granulomatosis with polyangiitis (GPA), which for a long time was interpreted as a pulmonary form of tuberculosis with the passage of anti-tuberculosis therapy without effect, which led to severe structural changes and resection of the lungs and deformation of the bones of the facial skeleton.Materials and methods. Patient S., 31 y. o., was hospitalized in the rheumatology department with complaints of bloody discharge from the nose with the formation of crusts, hearing loss on both sides, weakness, nose deformity. …”
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MANAGEMENT OF MAGNESIUM DEFICIENCY IN PREGNANT WOMEN: PHARMACOEPIDEMIOLOGIC STUDY by D. V. Blinov, U. V. Zimovina, E. M. Dzhobava

“…Objectives: to evaluate Mg deficiency incidence and management in a pregnant population monitored in Russian polyclinics. Materials and Methods: pregnant women (at any trimester) aged over 18 years were included. …”
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Analysis of the influence of renal replacement therapy on the development of carbohydrate metabolism disorders and glycemia variability in patients with chronic kidney disease by T. N. Markova, V. O. Yavorskaya, A. I. Ushakova, V. A. Berdinsky, T. V. Ibragimova, L. A. Kumakhova, A. D. Orlova, S. S. Usatiuk

“…BACKGROUND: Dialysis treatment is a risk factor for the development of carbohydrate metabolism disorders (CMD) and glycemia variability (VG) in patients with chronic kidney disease (CKD).AIM: To analyse the impact of renal replacement therapy (RRT) on the development of CMD in patients with CKD without a history of diabetes mellitus (DM).MATERIALS AND METHODS: 90 patients were examined with CKD without DM in the history (60 patients with CKD on RRT using program hemodialysis (pHD) and continuous ambulatory peritoneal dialysis (CAPD) and 30 patients with CKD 3–5 (without RRT)). …”
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Analysing the Effects of Longwave Diathermy on Quality of Life among Patients with Knee Osteoarthritis: A Pilot Study by Bhavna Anand, Pragya Kumar, Chitra Kataria

“…Aim: To evaluate and compare the effects of Pulsed Longwave Diathermy (PLWD) and Continuous Longwave Diathermy (CLWD) on QoL in individuals with knee OA, assessed across all domains of the World Health Organisation Quality of Life Brief version (WHOQoL-BREF): physical health, psychological health, social relationships and environmental health. Materials and Methods: A comparative pilot study was conducted in the Outpatient Department, Department of Physiotherapy, Amity Institute of Health Allied Sciences, Amity University, Noida, Uttar Pradesh, India, from January 2023 to May 2023. …”
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