Possibilities of Surgical Treatment of Vulva Cancer in the Context of the COVID-19 Pandemic by Sh. Kh. Gantsev, O. N. Lipatov, K. V. Menshikov

“…One of the approaches to reducing the volume of surgical treatment in such patients is the selective biopsy of the sentinel lymph node (SLN).Aim. …”
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Angiogenesis in endometrial cancer: clinical and biological significance by I. V. Maiborodin, M. A. Goncharov, A. I. Shevela, S. E. Krasilnikov, A. O. Shumeikina, V. I. Maiborodina

“…In addition, significant expression of the vascular network in an enlarged lymph node biopsied for diagnosis may be a symptom of the development of a malignant tumor in the lymph collection region, even in the absence of metastases.…”
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Feasibility of elective neck irradiation in treating node-negative nasopharyngeal carcinoma patients: a meta-analysis by Jianfeng Zhou, Hongyong Wang

“…The recognized target area for cervical prophylaxis in nasopharyngeal carcinoma is whole neck irradiation (WNI), Currently, some studies have confirmed that upper neck irradiation (UNI) may be feasible as a preventive measure for NPC patients with negative neck lymph nodes. This meta-analysis aimed to comprehensively investigate and compare the efficacy of selective UNI and WNI in improving survival outcomes and regional control in patients with lymph node-negative NPC.Materials and methodsA systematic search was conducted in PubMed, EMBASE, The Cochrane Library, and CNKI from inception to October 27, 2023, using a combination of Medical Subject Headings (MeSH) terms and free-text keywords related to “nasopharyngeal carcinoma,” “lymph node negative,” and “neck irradiation.” …”
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Non-typhoidal Salmonella among slaughterhouse workers and in the pork value chain in selected districts of Uganda by Velma Kivali, Velma Kivali, Velma Kivali, Kristina Roesel, Kristina Roesel, Ian Dohoo, Lordrick Alinaitwe, Lordrick Alinaitwe, Lordrick Alinaitwe, Lordrick Alinaitwe, James Katamba Bugeza, James Katamba Bugeza, Jolly Justine Hoona, Denis Rwabiita Mugizi, Denis Rwabiita Mugizi, Clovice Kankya, Sinh Dang-Xuan, Sinh Dang-Xuan, Istvan Szabo, Uwe Rösler, Anika Friese, Elizabeth A. J. Cook, Elizabeth A. J. Cook

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A Machine Learning Model for Predicting Breast Cancer Recurrence and Supporting Personalized Treatment Decisions Through Comprehensive Feature Selection and Explainable Ensemble Le... by Lee TF, Shiau JP, Chen CH, Yun WP, Wuu CS, Huang YJ, Yeh SA, Chen HC, Chao PJ

“…However, traditional risk prediction models often lack accuracy and do not fully capture the complexity of patient data.This study developed an ensemble learning model to predict breast cancer recurrence more accurately by integrating LASSO feature selection and multiple machine learning models. Using data from 1,131 breast cancer patients, the model identified six key predictors of recurrence, including lymph node positivity, ER status, Ki-67, lymphovascular invasion, tumor size, and age at diagnosis. …”
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Utility of [18F]FDG PET/CT in sarcoidosis management: A retrospective case series by Mourad Zekri, Majdouline Bel Lakhdar, Dounia Alami, Soumia Kriouile, Leila Achachi, Abdellah Achir, Hicham Harmouche, Ayat Mouaden, Hasnae Guerrouj, Imad Ghfir

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CLASSIFICATION OF PULMONARY METASTASES: POTENTIAL APPLICATION IN CLINICAL PRACTICE by E. I. Smolenov, Yu. A. Ragulin, O. V. Pikin

“…In patients having no lymph node involvement, better results were observed in patients with a solitary site of metastasis (Ms ), with a median survival of 58 months. …”
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Relevance of Platelet-lymphocyte Ratio in Tumor Characteristics and Survival in Clear Cell-renal Cell Carcinoma by Santhosh Srinivasan, Poulose Chally, Abdul Azeez, Pankaj Bhirud

“…PLR shown a strong link with both renal vein invasion (P = 0.029) and lymph node metastasis (P < 0.001) in our study, after being compared to tumor size, Fuhrman’s grading, metastasis-free survival, and lymph node metastasis. …”
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Expression of p53 protein in Barrett’s adenocarcinoma and adenocarcinoma of the gastric cardia and antrum by Jovanović Ivan, Todorović Vera N., Milosavljević Tomica, Micev Marijan, Peško Predrag, Bjelović Miloš, Mouzas Yoannis, Tzardi Maria

“…Patients with more advanced Barrett’s adenocarcinoma and in the cases of lymph node invasion revealed tendency for the greater p53 positivity compared with the early forms and lymph node-negative cases; however, this difference was not significant according to the statistical analysis. …”
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Evaluation of capability of ultrasound with elastometry and elastography for diagnosis of subclinical regional metastases of cancer of the oral mucosa by Yu. V. Alymov

“…Therefore, evaluation of the pathways of regional lymphatic outflow in oral mucosa cancer is of prime importance for disease prognosis and treatment selection. Ultrasound investigation (USI) is one of the main instrumental methods of regional lymph node investigation in oral mucosa cancer patients. …”
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Papillary thyroid cancer with translocation in the TPM3‑NTRK1 gene by M. R. Savchuk, N. V. Shved, N. A. Savelov, I. L. Plaksa

“…The morphological selection criteria for the immunohistochemical study were: metastatic lesions of the lymph nodes, microcalcifications, extrathyroid spread of the tumor, the presence of a capsule / intratumorous areas of connective tissue, invasion (into the tumor capsule, blood vessels, lymphatic vessels), the presence of intranuclear pseudo-inclusions, the follicle quantity &lt;5 %. …”
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DIFFUSION-WEIGHTED IMAGING FOR DIFFERENTIATING MALIGNANT FROM BENIGN MEDIASTINAL LYMPHADENOPATHY by A. V. Sudarkina, A. P. Dergilev, N. A. Gorbunov, V. V. Kozlov, Yu. A. Fokina, I. P. Klimova, P. A. Yagubkin

“…In all patients one of the biggest solid lymph nodes was selected for ADC measurements and mean ADCs of each node were recorded. …”
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Androgen receptor positive triple negative breast cancer: Clinicopathologic, prognostic, and predictive features. by Kristine Astvatsaturyan, Yong Yue, Ann E Walts, Shikha Bose

“…Patients' age, tumor size, tumor grade, lymph node status, proliferation rate, immunopositivity for EGFR, CK5/6, Ki-67, and disease free survival (DFS) were evaluated statistically.…”
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Role of the anatomic site in the association of HLA class I antigen expression level in metastases with clinical response to ipilimumab therapy in patients with melanoma by Timea Balatoni, Soldano Ferrone, Judit Olah, Andrea Ladányi, Eszter Papp, Anita Mohos, Anita Varga, Zsuzsanna Lengyel, Gabriella Emri

“…The aim of our study was to test human leukocyte antigen (HLA) class I and II expression in melanoma metastases as potential biomarkers of response to ipilimumab and survival in patients with metastatic melanoma, since these molecules play a crucial role in the interactions of malignant cells with host’s immune system.Materials and methods HLA class I and II antigen expression level in pretreatment surgical tissue samples (50 lymph node and 35 cutaneous or subcutaneous metastases) from 30 patients was analyzed by immunohistochemical staining with monoclonal antibodies. …”
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The Role of C11-Choline-PET/CT-Guided Secondary Lymphadenectomy in Patients with PSA Failure after Radical Prostatectomy: Lessons Learned from Eight Cases by Thomas Martini, Roman Mayr, Emanuela Trenti, Salvatore Palermo, Evi Comploj, Armin Pycha, Maria Zywica, Michele Lodde

“…Two of the latter had no histological lymph node metastases. Conclusions. Because 50% of our patients showed an initial PSA response, our data suggest that positive 11C-choline-PET/CT after RP and BF could help to select patients that could benefit from secondary LAD.…”
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Correlation of P53 expression and epithelial-mesenchymal transition in non-small cell lung cancer by Xiangmei Wu, Lijiang Duan

“…Results: The positive expression rate of P53 and the incidence of EMT in NSCLC were closely linked to TNM stages, differentiation degree, and lymph node metastasis (P < 0.05). A positive association was found between P53 and EMT (r = 0.380, P < 0.05). …”
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Metastases of Merkel cell carcinoma in terms of diagnosing carcinomas with unknown primary localization. by О V. Poslavska

“…The problem of MCC, which determines the relevance of its research, is often a high frequency of local recurrence, regional lymph node metastasis and further hematogenous and/or distant lymphogenous dissemination. …”
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Assessing the value of artificial intelligence-based image analysis for pre-operative surgical planning of neck dissections and iENE detection in head and neck cancer patients by Benedikt Schmidl, Cosima C. Hoch, Robert Walter, Markus Wirth, Barbara Wollenberg, Timon Hussain

“…Abstract Objectives Accurate preoperative detection and analysis of lymph node metastasis (LNM) in head and neck squamous cell carcinoma (HNSCC) is essential for the surgical planning and execution of a neck dissection and may directly affect the morbidity and prognosis of patients. …”
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Distinguishing atypical parotid carcinomas and pleomorphic adenomas based on multiphasic computed tomography radiomics nomogram: a multicenter study by Lin-Wen Huang, Jian-Chao Liang, Pei-Kun Cai, Zhi-Ping Cai, Mei-Lin Chen, Jia-Wei Pan, Yong-Feng Wen, Yun-Jun Yang, Zhen-Yu Xu, Ya-Bin Jin, Zhi-Feng Xu

“…ObjectiveThis study aimed to develop, validate, and test a comprehensive radiomics prediction model using clinical data and contrast-enhanced multiphasic computed tomography (CT) scans for differentiating between atypical parotid carcinomas (PCAs) and pleomorphic adenomas (PAs) within a multicenter cohort.Materials and methodsThe study involved 218 patients diagnosed with either PAs (n=162) or atypical PCAs (n=56) (no invasion of adjacent tissues or lymph node metastases) across three anonymized hospitals, divided into a training set (n=175) and a validation set (n=43). …”
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Predicting the hypoxic volume of head and neck tumors from fluorodeoxyglucose positron emission tomography images using artificial intelligence by Wei Zhao, Milan Grkovski, Heiko Schoder, Aditya P. Apte, John Humm, Nancy Y. Lee, Joseph O. Deasy, Harini Veeraraghavan

“…Hence, we tested the hypothesis that an artificial intelligence (AI) model could synthesize 18F-FMISO-like images from routinely acquired 18F-fluorodeoxyglucose (18F-FDG) PET images in order to predict primary tumor or metastatic lymph node hypoxic volumes. Materials and methods: One hundred and thirty-four (training = 84, validation = 13, testing = 21, additional testing = 16) HN carcinoma patients, treated with chemoradiotherapy between 2011 and 2018 and scanned at treatment baseline with 18F-FDG PET/computed tomography (CT) and 18F-FMISO dynamic PET/CT, were analyzed. …”
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