Diagnostic and prognostic significance of detecting mutations in the <i>BRAF, TERT, RAS, RET/PTC, PAX8/PPARG</i> in the material of fine needle aspiration biopsy thyroid nodules in... by A. A. Musaelyan, S. V. Lapin, V. D. Nazarov, E. S. Kozorezova, S. L. Vorobyev, S. V. Orlov

“…The prevalence of mutations in benign formations was 4.7 %. mutations in RAS genes were also found in them in group 1, mutation BRAF V600E was associated with the presence of extrathyroid invasion (p = 0.024), vascular invasion (p = 0.018), and lymph node metastases (p = 0.018). In group 2, using the genetic panel sensitivity and specificity were equal: 36.4 and 93.9 %, respectively. positive and negative predictive values were 66.7 and 81.6 %, respectively. …”
Get full text

Exploring the Efficacy of Artificial Intelligence-Based Computer-Aided Detection for Breast Cancer Detection on Digital Mammograms by Sunhee Bien, Ga Eun Park, Bong Joo Kang, Sung Hun Kim

“…Mammographically occult cases were defined as those with negative mammographic findings by two radiologists. Results AI-CAD detected 81.4% (219/269) of cancers, with higher detection rates occurring for larger lesion sizes, high histologic grades, lymph node involvement, and advanced stages. …”
Get full text

The Clinical Application of Raman Spectroscopy for Breast Cancer Detection by Pin Gao, Bing Han, Ye Du, Gang Zhao, Zhigang Yu, Weiqing Xu, Chao Zheng, Zhimin Fan

Get full text

NUCLEAR MEDICINE IMAGING IN THE DETECTION OF LOCALLY ADVANCED LARYNGEAL AND HYPOPHARYNGEAL CANCER by A. A. Medvedeva, V. I. Chernov, R. V. Zeltchan, I. G. Sinilkin, I. G. Frolova, S. V. Chizevskaya, E. L. Choynzonov, O. V. Cheremisina, A. V. Goldberg

“…The 99mTc-MIBI uptake in metastatic lymph nodes was visualized in 2 (17 %) of the 12 patients. 28 SLNs were detected by SPECT and 31 SLNs were identifed using the intraoperative gamma probe. …”
Get full text

Relapse detection in the Danish surveillance program of patients with clinical stage I seminoma: a nationwide study by Niklas B. Lindahl, Jakob Lauritsen, Thomas Wagner, Gedske Daugaard, Mikkel Bandak

“…In total, 134 (92%) relapses were localized to retroperitoneal lymph nodes, primarily without additional spread. …”
Get full text

A Rare Case of Uterine Serous Carcinoma: Importance of Early Detection and Comprehensive Treatment in Postmenopausal Women by Amjad Hijazi, Gieth Alahdab, Aland Oso, Ahmad Abboud, Safa K. Salman

Get full text

Evaluation of Long-Term Lymphedema Rate in Patients With Subclinical Lymphedema Diagnosed in the Preoperative Period via Bioimpedance by Zeynep Erdoğan İyigün, Tolga Ozmen, Serkan İlgün, Cansu Nakipoğlu, Enver Özkurt, Filiz Çelebi, Çağlar Ünal, Alper Öztürk, Gül Alço, Çetin Ordu, Gürsel Soybir

“…In multivariable analysis, the positive lymph node count was identified as an independent variable in these patients. …”
Get full text

PET/CT WITH 68GA-FAPI46 FOR THE DETECTION OF PRIMARY AND METASTATIC LESIONS IN PATIENTS WITH DIFFERENT TYPES OF CANCER. INITIAL EXPERIENCE by Lilian Yuri Itaya Yamaga, Gustavo Borges da Silva Teles, Durval Santos, Oren Smaletz, Roberto Pestana, Poliana Biasi, Mauricio Fernandes, Solange Amorim Nogueira, Marycel Figols Barboza, Taise Vitor, Jairo Wagner

“…The diagnostic performance was high due to a favorable physiological organ distribution and low background signal leading to the detection of most metastatic lesions especially in lymph nodes, pleura, peritoneum, skeleton, liver and central nervous system. …”
Get full text

Development and validation of highly sensitive multiplex real-time RT-PCR assay for detection of classical swine fever virus genome by A. S. Sadchikova, A. S. Igolkin, R. S. Chernyshev, A. A. Kozlov, I. S. Kolbin, A. V. Sprygin, D. A. Biryuchenkov, I. A. Chvala, A. Mazloum

“…For comparative analysis of the developed as say sensitivity, swabs, samples of organs and tissues collected from pigs experimentally infected with an epizootic strain of the classical swine fever virus (spleen, kidney, liver, blood, lymph nodes, rectal and oral smears), animal-contaminated feed and virus-containing material with known virus titres were also tested in parallel with coded test systems No. x1 andx2. …”
Get full text

Conformal radiotherapy in combination with cetuximab for stage Т1–2 tongue cancer with N1–2b regional metastases detected after preventive lymphadenectomy by D. V. Sikorsky, N. V. Kanishcheva, S. O. Podvyaznikov, D. V. Skamnitsky, S. V. Smetanina, A. M. Ermolaeva, K. V. Bazanov, S. R. Pakhomov

“…The study objective is to analyze the experience of conformal radiotherapy in combination with cetuximab for cervical lymph node (LN) metastasis in patients with early-stage tongue cancer who had undergone multicomponent surgeries.Materials and methods. …”
Get full text

Assessing the value of artificial intelligence-based image analysis for pre-operative surgical planning of neck dissections and iENE detection in head and neck cancer patients by Benedikt Schmidl, Cosima C. Hoch, Robert Walter, Markus Wirth, Barbara Wollenberg, Timon Hussain

“…Abstract Objectives Accurate preoperative detection and analysis of lymph node metastasis (LNM) in head and neck squamous cell carcinoma (HNSCC) is essential for the surgical planning and execution of a neck dissection and may directly affect the morbidity and prognosis of patients. …”
Get full text

Thirty years of population-based breast cancer screening in Iceland: a comparison of quality indicators and tumour characteristics between women aged 40–49 and 50–69 years by Alfheidur Haraldsdottir, Helgi Birgisson, Agust I. Agustsson, Laufey Tryggvadottir

“…Among screen-detected cases, women aged 40–49 years exhibited a higher proportion of tumours larger than 20 mm (29.7% vs. 21.7%), more lymph node positivity (41.2% vs. 28.2%) and higher human epidermal growth factor receptor 2 (HER2) positivity (18.6% vs. 11.8%), compared to those aged 50–69 years. …”
Get full text

Magnetic Nanoparticles: Advances in Synthesis, Sensing, and Theragnostic Applications by Adeyemi O. Adeeyo, Mercy A. Alabi, Joshua A. Oyetade, Thabo T. I. Nkambule, Bhekie B. Mamba, Adewale O. Oladipo, Rachel Makungo, Titus A. M. Msagati

Get full text

Tumour budding in invasive ductal breast carcinomas: correlation with clinicopathological prognostic parameters and hormone receptor status by Sachin Sebastian Francis, Swati Sharma

“…Univariate and multivariate logistic regression analyses were also done to demonstrate the significance of association.ResultsHigh-grade PTB showed significant associations with LVI (p = 0.046), PNI (p = 0.017), and axillary lymph node involvement (p = 0.021). In contrast, high-grade ITB was only significantly correlated with axillary lymph node involvement (p = 0.044). …”
Get full text

CAUSE OF RELAPSE GASTRIC CANCER PATIENTS AFTER RADICAL TREATMENT by A. G. Baryshev, V. A. Porhanov, A. Y. Popov, A. N. Lishenko, N. V. Hachaturyan, D. A. Valyakis, M. V. Bodnya

“…Material and methods. Using the Kaplan-Meier method and analysis of variance, long-term treatment outcomes were analyzed in 662 patients with gastric cancer, who underwent either limited/standard lymph node dissection (D1) or extended lymph node dissection (D2). …”
Get full text

Role of diffusion weighted imaging and contrast-enhanced MRI in the evaluation of intrapelvic recurrence of gynecological malignant tumor. by Kazuhiro Kitajima, Utaru Tanaka, Yoshiko Ueno, Tetsuo Maeda, Yuko Suenaga, Satoru Takahashi, Masashi Deguchi, Yoshiya Miyahara, Yasuhiko Ebina, Hideto Yamada, Masakatsu Tsurusaki, Yukihisa Tamaki, Kazuro Sugimura

“…Diagnostic performance for detection of local recurrence, pelvic lymph node and bone metastases, and peritoneal lesions was evaluated by consensus reading of two experienced radiologists using a 5-point scoring system, and compared among T2WI with unenhanced T1-weighted imaging (T1WI) (protocol A), a combination of protocol A and DWI (protocol B), and a combination of protocol B and contrast-enhanced imaging (protocol C). …”
Get full text

Expression of CXCR-4 and CD 133 and it’s Correlation with Prognostic Pathologic Factors in Resectable Oral Squamous Cell Carcinoma: A Research Protocol by Nirlipta Swain, Arvind Shridhar Bhake

“…Aim: This study aims to evaluate the immunohistochemical expression of CXCR-4 and CD133 in resectable OSCC and analyse their correlation with key prognostic pathological factors, including tumour grade, tumour size (T-stage), Depth of Invasion (DOI), Lymphovascular Invasion (LVI), Perineural Invasion (PNI), lymph node metastasis (N-stage), and Lymph node metastasis and surgical margin status. …”
Get full text

LEVELS I–VII FOLLOWING THYROIDECTOMY FOR PAPILLARY THYROID CANCER by V. S. Parshin, A. A. Veselova, V. S. Medvedev, S. A. Ivanov, A. D. Kaprin

“…The aim of this study was to assess the potential utility of neck ultrasound in diagnosing cervical lymph node metastases (levels I–VII) in patients who underwent surgical treatment for papillary thyroid cancer.Material and Methods. …”
Get full text

The Role of C11-Choline-PET/CT-Guided Secondary Lymphadenectomy in Patients with PSA Failure after Radical Prostatectomy: Lessons Learned from Eight Cases by Thomas Martini, Roman Mayr, Emanuela Trenti, Salvatore Palermo, Evi Comploj, Armin Pycha, Maria Zywica, Michele Lodde

“…The aim of this paper was to evaluate the PSA response in patients with BF after radical prostatectomy (RP) who underwent secondary lymphadenectomy (LAD) due to 11C-choline-PET/CT findings. Material and Methods. Eight patients with BF and positive lymph nodes in 11C-choline-PET/CT after RP were retrospectively included in the study. …”
Get full text

Evaluation of C-X-C chemokine receptor type 4 (CXCR4) and Peroxisome proliferator-activated receptor gamma (PPAR-γ) expression in colorectal carcinoma: Relation to the available cl... by Asmaa E. Bedeer, Nehal Abd El-Ghaffar Heabah

“…Results: CXCR4 expression was detected in 76% of studied cases. High CXCR4 expression showed significant associations with the depth of tumor invasion (P = 0.024), lymph node metastasis (P = 0.009), advanced tumor stage (P = 0.001) and the presence of vascular invasion (P = 0.035). …”
Get full text