Tumor budding as a prognostic criterion of colorectal cancer by I. I. Yakovtsova, V. M. Cheverda, O. V. Dolhaia, A. S. Yakymenko, I. V. Ivakhno

“…There was a statistically significant relationship between TB and metastatic spreading of CRC to regional lymph nodes (Р < 0.001). Metastasis was associated with 3 stage of TB, absence of metastasis was typical for CRC without TB. …”
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Tumores neuroendocrinos gastroenteropancreáticos: un estudio retrospectivo en el suroccidente colombiano by J.C. Bravo-Ocaña, N. López-Moreno, E.D. Salazar-Cardona, A.F. Mejía-Hurtado, V. Gutiérrez-Aragón, M. Gonzáles-Hurtado, L.A. Satizabal-Mayor, J.F. Lbasseauny-Morales, N. Rojas-Rojas, C.A. Rojas-Rodríguez

“…Early tumors are mainly located in the stomach and advanced tumors in the small intestine, with metastases in the liver and regional lymph nodes. The present study suggests the importance of disease awareness in the early detection of GEP-NETs; said factor, combined with timely interdisciplinary management, could significantly impact patient outcomes.…”
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Improving the Anti-Tumor Effect of Indoleamine 2,3-Dioxygenase Inhibitor CY1-4 by CY1-4 Nano-Skeleton Drug Delivery System by Hui Li, Junwei Liu, Jingru Wang, Zhuoyue Li, Jianming Yu, Xu Huang, Bingchuan Wan, Xiangbao Meng, Xuan Zhang

“…In B16F10 tumor-bearing mice, MSNM@CY1-4 significantly inhibited tumor growth, prolonged survival time, significantly inhibited IDO activity in blood and tumor tissues, and reduced Tregs in tumor tissues and tumor-draining lymph nodes to improve anti-tumor efficacy. <b>Conclusions</b>: The nano-skeleton drug delivery system (MSNM@CY1-4) constructed in this study is a potential drug delivery platform for improving the anti-tumor effect of oral poorly water-soluble CY1-4.…”
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Ultrasound-enhanced fine-needle biopsy improves tissue yield in head and neck tumors ex vivo by Minna Rehell, Yohann Le Bourlout, Jetta Kelppe, Jaana Rautava, Emanuele Perra, Jouni Rantanen, Gösta Ehnholm, Nick Hayward, Kristofer Nyman, Kenneth P. H. Pritzker, Jussi Tarkkanen, Timo Atula, Heikki J. Nieminen, Katri L S Aro

“…Parotid gland tumors (PGT; N = 10) and neck lymph nodes of patients with head and neck cancer (HNC; N = 10) were resected and biopsied using three techniques: USeFNAB, FNAB, and CNB which served as a comparative method. …”
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Diagnostic potential of plasma CD30(+) small extracellular vesicles in Hodgkin lymphoma by K. E. Katsuba, L. A. Kramynin, M. A. Slyusarenko, A. V. Shalaev, V. V. Sharoyko, A. A. Valitova, A. S. Artem’eva, P. I. Krzhivitskiy, L. V. Filatova, A. V. Malek

“…The plasma concentration of CD30(+)SEV in patients with Hodgkin lymphoma correlates with the quantity of CD30(+) cells in tissues of biopsied lymph nodes (r = 0.8) and the total lesion glycolysis estimated by PET/CT (r = 0.9). …”
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OSTEOPROTEGERIN AS A PREDICTIVE MARKER OF THE COURSE OF BREAST CANCER by S. I. Zabroda, E. A. Maslyukova, L. I. Korytova, K. M. Pozharisskiy, G. A. Raskin, O. V. Korytov

“…When analyzing clinical and pathological characteristics of BC patients, taking into consideration OPG expression, there were noticed no reliable differences with respect to availability  or absence of affected regional lymph nodes, category T and Ki-67 indice. The group with positive estogen-progesteron receptors showed reliably more often the high values of OPG than the group with negative receptors (p &lt; 0,05). …”
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Whole-Body Diffusion-Weighted Magnetic Resonance Imaging and Positron Emission Tomography Combined with Computed Tomography in the Staging of Lymphomas by S. A. Kharuzhyk, E. A. Zhavrid, A. V. Dzyuban, K. V. Poddubnyy, E. V. Sukolinskaya, O. A. Kalenik

“…The techniques were compared for their efficiency in diagnosing damage to lymph nodes (LNs) and organs and in determining the stage of lymphoma.Results. …”
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Modern options of endoscopic retrograde stenting of bile ducts in treatment of obstructive jaundice at malignant pancreatobiliary tumors by S. A. Budzinsky, S. G. Shapovalyants, Ye. D. Fedorov, A. G. Mylnikov, D. V. Bakhtiozina

“…With the help of the comprehensive diagnostic program providing ultrasound investigation, computer tomography, endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography, it was possible to determine in 207 (72,1%) cases the distal block of biliary tract due to tumors of MDP, terminal CBD portion, distal part of common bile duct and pancreatic head, and the proximal block in 80 (27,9%) cases at lesions of gallbladder, hepatico-choledochal duct, lobar hepatic ducts or compression of proximal biliary tree by lymph nodes of hepatoduodenal ligament.Results. Bilioduodenal stents at 272 (94,8%) patients were installed after preliminarily endoscopic papillosphincterotomy (EPST). …”
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STRUCTURAL FEATURES OF PURULENT INFLAMMATORY DISEASES OF THE MAXILLOFACIAL REGION IN RESIDENTS OF THE POLTAVA REGION by D.V. Steblovskyi, M.G. Skikevich, V.V. Bondarenko

“…As etiological factors for purulent inflammatory diseases of the maxillofacial area can be diseases of the skin of the face and neck, lymph nodes, ENT diseases. The leading role in purulent inflammatory diseases of the maxillofacial area is occupied by odontogenic cause. …”
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Utility of [18F]FDG PET/CT in sarcoidosis management: A retrospective case series by Mourad Zekri, Majdouline Bel Lakhdar, Dounia Alami, Soumia Kriouile, Leila Achachi, Abdellah Achir, Hicham Harmouche, Ayat Mouaden, Hasnae Guerrouj, Imad Ghfir

“…Additionally, 60% of patients displayed associated extrathoracic activity, mainly in peripheral lymph nodes, spleen, and bone. Cardiac activity was reported in two patients. [18F]FDG PET/CT prompted a diagnostic biopsy in 32% of patients. [18F]FDG PET/CT had an impact on therapeutic decision-making in 60% of patients. …”
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Risk factors for rectal bleeding in prostate cancer after radiotherapy with a validation of current rectal dose constraints by Ellen Lund Schaldemose, Christine Vestergaard Madsen, Ahmed Hussein Zedan, Martin Berg, Henrik Dahl Nissen, Terje Andersen, Bjarke Mortensen, Lars Ulrik Fokdal

“…EBRT consisted of 56 Gy/39 fractions to the prostate, elective lymph nodes, and seminal vesicles with an integrated boost of 78 Gy to the prostate alone (≤T3a) or to the prostate and seminal vesicles (T3b). …”
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3D-modeling Capabilities in Assessing Resectability of Pancreatic Head Tumors by A. S. Kudashkina, I. G. Kamyshanskaya, K. V. Pavelets, D. S. Rusanov, S. А. Kalyuzhnyy

“…This method allows to objectively determine the localization and prevalence of the tumor process on adjacent anatomical structures, as well as visually demonstrate the metastatic lesion of regional lymph nodes. By the parameters of diagnostic efficiency, 3D models are maximally close to the intraoperative picture, which allows planning both the volume and the course of surgical intervention.…”
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Analysis of survival rates and evaluation of prognostic factors in patients with lung metastases from renal cell carcinoma by D. V. Semyonov, R. V. Orlova, V. I. Shirokorad, S. V. Kostritsky, N. A. Karlova

“…The 3- and 5-year OS rates in patients with lung metastases from RCC (N=655) were 48 % [95 % ci 45–53 %] and 27 % [95 % ci 23–31 %], respectively, with a median OS of 34.9 months [95 % ci 30.4–37.4]. in univariate analysis, ECOG status (p&lt;0.001), histological subtype (p&lt;0.001), Fuhrman grade of tumor differentiation (p&lt;0.001), type and number of metastases (p&lt;0.001), metastases to the bones and liver (p&lt;0.001), lymph nodes (p=0.001), prognosis according to IMDC(p&lt;0.001), nephrectomy and metastasectomy (p&lt;0.001) had a negative impact on OS in patients with lung metastases from RCC. …”
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Development of in vitro laboratory models of the tumor immune microenvironment to evaluate quality parameters and specific efficacy of the dendritic cell vaccine by T. L. Nekhaeva, A. B. Danilova, E. I. Fedoros, N. A. Efremova, N. V. Emelyanova, M. L. Blokhina, M. N. Yurova, M. L. Tyndyk, I. A. Baldueva

“…We revealed that mature DCs (CD83+CD1a-) had a high expression of antigen presenting molecules (HLA-DR) and those providing migration of DCs into lymph nodes (CCR7) as well as costimulatory molecules CD80 and CD86 as compared to immature DCs (CD83-CD1a+). …”
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High-Frequency Ultrasonography As An Innovative Diagnostic Method in Dermatology by Aneta Rasińska, Piotr Rzyczniok, Anna Rzyczniok, Weronika Rasińska, Justyna Jachimczak, Filip Grydź, Joanna Filipow, Anna Rebizak, Paulina Bala, Aneta Rostkowska, Sebastian Kupisiak, Natalia Pasierb, Justyna Matusik, Mateusz Kopczyński

“…Frequencies of 20–30 MHz visualise full dermis, 50 MHz epidermis/upper dermis, while lower (7–12 MHz) probes image deeper lesions and lymph nodes. …”
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PREMORBIDITY IN ACUTE INFLAMMATION OF THE MAXILLOFACIAL AREA IN CHILDREN by P.І. Tkachenko, S.О. Bilokon, Yu.V. Popelo, N.M. Korotych, N.M. Lokhmatova, О.B. Dolenko

“…The analysis of premorbid state of 240 patients with acute purulent lymphadenitis has shown that the onset of the diseases was triggered by the experienced ARVI in 89 patients (37%) and in 37 cases (15%) inflammation of the lymph nodes coincided with manifestations of acute pathology of the ENT organs; in 34 (14%) cases it was combined with acute inflammation of the bronchopulmonary system, in 23 (10%) cases with disorder of the gastrointestinal tract (GIT), in 13 (6%) cases it was provoked by acute periodontitis and exacerbation of chronic periodontitis in temporary and permanent molars of the mandible. …”
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Acral Melanoma in the Caucasian Population: A Comprehensive Cohort Study on Epidemiological, Clinicopathological, and Prognostic Features by J. Angel-Baldo, S. Podlipnik, A. Azón, A. Boada, A. Arrieta, J. Marcoval, C. López-Sánchez, M. Sàbat, S. Segura, D. Bodet, N. Curcó, D. Lopez-Castillo, J. Solà, M. Quintana-Codina, C. Baliu-Piqué, M. Just-Sarobé, S. Martín-Sala, J. Malvehy, S. Puig, C. Carrera, R.M. Marti, Clara Matas-Nadal, Xavier Soria, Sonia Gatius, Felip Vilardell, Inma Gil, Cristina Grau, Fani Martínez, Nelson Lobos, Oriol Yélamos, Joan Dalmau, Carlos González-Cruz, Helena Hilari, Paola Pasquali, Marc Sagristà, María Rosa Olivella-Garcés, Montserrat Bonfill-Ortí, Josep Ramón Ferreres, Ane Jaka, Ariadna Quer, Nina Richarz, Inés Zarzoso Muñoz, Emili Masferrer, Pedro Zaballos, Manel Formigon, Loida Galvany, Marta Alegre, Anna Sánchez-Puigdollers, Nerea Mohino-Farré

“…Foot melanomas had a higher proportion of invasive cases (80.8% vs 69.8%; p = 0.003), stages III and IV at diagnosis (24.8% vs 11.7%; p < 0.001), thicker Breslow depth (2.8 mm vs 2.0 mm; p = 0.021) and a higher rate of positive sentinel lymph node biopsy (SLNB) (30.7% vs 15.7%; p = 0.012). …”
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