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641
A Comprehensive Review of Sarcoidosis: From Clinical Manifestations to Management Strategies
Published 2024-12-01“… Introduction and purpose: Sarcoidosis is a complex, multi – system disease characterized by the formation of non – caseating granulomas that can affect nearly every organ in the body, though lungs and lymph nodes are the most commonly involved. The disease's clinical presentation is highly variable, ranging from asymptomatic cases to severe, organ-threatening manifestations, with significant implications for diagnosis and treatment. …”
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642
Prognostic Value of PRAME Activity in Tumor Cells of Follicular Lymphoma
Published 2019-03-01“…To set survival parameters for follicular lymphoma (FL) patients with different PRAME expression levels in tumor cells. Materials & Methods. The study was conducted on samples of lymph nodes, blood, and bone marrow of 34 patients with newly diagnosed FL. …”
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643
Prognostic Impact of Klintrup–Mäkinen (KM) Score in Gastric Cancer and Its Association with Pathological Parameters
Published 2025-04-01“…Patients with low KM grades demonstrated significantly more aggressive tumor features, including a higher prevalence of Borrmann classification types III-IV (75.8% vs. 54.9%, <i>p</i> = 0.01), poorly differentiated histology (74.1% vs. 33.8%, <i>p</i> < 0.0001), advanced T stage (93.5% vs. 80.2%, <i>p</i> = 0.04), and lymph node involvement (87% vs. 60.5%, <i>p</i> = 0.0008). …”
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644
NUCLEAR MEDICINE IMAGING IN THE DETECTION OF LOCALLY ADVANCED LARYNGEAL AND HYPOPHARYNGEAL CANCER
Published 2017-12-01“…The 99mTc-MIBI uptake in metastatic lymph nodes was visualized in 2 (17 %) of the 12 patients. 28 SLNs were detected by SPECT and 31 SLNs were identifed using the intraoperative gamma probe. …”
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645
Predictive factors associated with acute radiation dermatitis in patients with breast cancer: a retrospective cohort study
Published 2025-03-01“…However, radiation to both the primary site and regional lymph nodes (AOR = 0.81; 95% CI [0.41–1.59]; p-value = 0.538) and targeted therapy (AOR = 0.72; 95% CI [0.43–1.20]; p-value = 0.210) did not significantly affect the risk of moderate to severe ARD. …”
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646
Assessment of the allergenic and immunotoxic properties of the recombinant non-immunogenic staphylokinase in preclinical and clinical trials
Published 2025-07-01“…Suvorov) in guinea pigs, did not affect the cellular capacity of popliteal lymph nodes (reaction index 0.91), did not affect the number of nucleated and antibody-forming cells in the spleen of mice. …”
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647
Prediction of one-year recurrence among breast cancer patients undergone surgery using artificial intelligence-based algorithms: a retrospective study on prognostic factors
Published 2025-05-01“…As the analysis of SHapley Additive exPlanations indicated, the tumor grade, HER-2, and the number of lymph nodes involved were more significant predictors. …”
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648
Transcervical approach for oropharyngeal cancer
Published 2018-07-01“…Among them 28 (60 %) were diagnosed with T3–T4 primary tumors; 37 (79 %) patients hadmetastases in lymph nodes. Perioperative tracheostomy was performed in all cases. …”
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649
Distribution of chronic wasting disease (CWD) prions in tissues from experimentally exposed coyotes (Canis latrans).
Published 2025-01-01“…Moreover, prion seeding activity was identified in other tissues, including lymph nodes and lungs. These results provide additional information about the dynamics of CWD prions in the environment and show the initial fate of prions after ingestion by a canid species that is a carnivorous predator and scavenger.…”
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650
The Role of Adjuvant Hormonal Treatment after Surgery for Localized High-Risk Prostate Cancer: Results of a Matched Multiinstitutional Analysis
Published 2012-01-01“…To assess the role of adjuvant androgen deprivation therapy (ADT) in high-risk prostate cancer patients (PCa) after surgery. Materials and Methods. The analysis case matched 172 high-risk PCa patients with positive section margins or non-organ confined disease and negative lymph nodes to receive adjuvant ADT (group 1, n=86) or no adjuvant ADT (group 2, n=86). …”
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651
Clinical profile, surgical management, and outcome of inferior vena cava tumors- A single-team experience
Published 2025-08-01“…Two patients diagnosed with leiomyosarcoma and metastatic para-caval lymph nodes were referred for adjuvant radiotherapy. …”
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652
A Bionic “Trojan Horse”-like Nanovesicle Delivery System Hybridized with BCG Cytoplasmic Membrane and Melanoma Cell Membrane for Cancer Immunotherapy
Published 2025-04-01“…In order to further confirm the material’s capacity to activate the immune system and its ability to inhibit tumor growth, the activation of DC and T cells in mouse draining lymph nodes and the concentration of anti-tumor cytokines were measured. …”
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653
Evolution of treatment for children with esthesioneuroblastoma (1969–2019)
Published 2021-11-01“…The affected cervical lymph nodes were irradiated in 10 (35 %) patients (total focal dose 40 Gy). …”
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654
Lung cancer in patients with COPD and factors associated with reduced survival
Published 2022-10-01“…The presence of certain types of metastases, such as metastatic lesions of the pleura, adrenal glands, distant non-regional lymph nodes, and bones should also be noted as negative factors for survival. …”
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655
Expression of the cytoskeletal proteins – cytokeratins and beta-III tubulin in human melanoma cell lines from the collection of N. N. Blokhin National Medical Research Center of On...
Published 2023-10-01“…Blokhin National Medical Research Center of Oncology, and 18 of which were isolated from tumor metastases in the lymph nodes, soft tissues or subcutaneously. The level of TUBB3 expression and de novo expression of CKs in vimentin-expressing cells (CK + Vim) were assessed by an immunofluorescent method and flow cytometry.Results. …”
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656
Immediate 2-Stage breast reconstruction outcomes after proton or photon postmastectomy radiotherapy
Published 2025-09-01“…The small number of events (n = 16) precluded multivariable analysis of reconstruction failure; on univariate analysis, receipt of a chest wall boost [HR: 4.98 (95 % CI: 1.12–22.10), p = 0.035] and/or lymph node boost [HR: 3.66 (95 % CI: 1.25–10.73), p = 0.018] were associated with reconstruction failure. …”
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657
Prognostic Value of the PRAME Gene Expression in T-Cell Lymphoproliferative Disorders
Published 2018-12-01“…To assess the clinical significance of the PRAME gene expression in T-CL. Materials & Methods. PRAME gene expression level was measured in samples of lymph nodes, blood, and bone marrow from 35 T-CL patients. …”
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658
Local-free recurrence survival after breast-conserving surgery and the breast cancer complex treatment
Published 2021-04-01“…The incidence of cancer in situ was higher in the OBS group: 14.7% vs. 3.3% in the RBR group (p < 0.001), metastases in regional lymph nodes were more frequent in the RBR group: 34.3% against 20.3% in OBS (p < 0.001). …”
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659
Association of pSTAT3, pSyk with c-Myc, p53, BCL2 proteins expression and survival of patients with diffuse large B-cell lymphoma
Published 2022-04-01“…In this regard, the problem of developing additional predictors of DLBCL course remains relevant today and is directly related to the molecular pathogenesis of the disease.The objective: to determine the relationship of pSTAT3, pSyk with c-Myc, p53, BCL2 oncoproteins expression and survival of DLBCL patients.Materials and methods. Biopsy specimens of lymph nodes and other organs and tissues obtained from 100 patients with newly diagnosed DLBCL were used for the study. …”
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660
The use of low doses of gabapentin in patients with neuropathic pain and with thrombocytopenia
Published 2024-06-01“…The localization of pain was different, pain predominated in the lower extremities (63% (n = 15), 95% CI: 43 – 79%), caused by peripheral polyneuropathy of predominantly toxic origin (vincristine, bortezomib), and pain was also caused by the course of the underlying disease: cephalalgia and neck pain, this pain was caused by compression of the nerve structures by the lymph nodes, postherpetic neuralgia, trigeminal neuralgia caused by tumor growth. …”
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