Does Platelet Mass Index Play a Role in Predicting Biochemical Recurrence in Localized Prostate Cancer? by Reha Girgin, Önder Çınar, Ersan Bulut, Cemal Ferhat Önal

“…There was no correlation of PMI value with PSA, pathological stage, Gleason score, lymph node involvement, tumor volume, surgical margin positivity, and biochemical recurrence. …”
Get full text

Role of diffusion weighted imaging and contrast-enhanced MRI in the evaluation of intrapelvic recurrence of gynecological malignant tumor. by Kazuhiro Kitajima, Utaru Tanaka, Yoshiko Ueno, Tetsuo Maeda, Yuko Suenaga, Satoru Takahashi, Masashi Deguchi, Yoshiya Miyahara, Yasuhiko Ebina, Hideto Yamada, Masakatsu Tsurusaki, Yukihisa Tamaki, Kazuro Sugimura

“…<h4>Results</h4>Locally recurrent disease, lymph node recurrence, peritoneal dissemination and bone metastases were present in 48.4%, 29.0%, 16.1%, and 6.5% of the patients, respectively. …”
Get full text

DIFFUSION-WEIGHTED IMAGING FOR DIFFERENTIATING MALIGNANT FROM BENIGN MEDIASTINAL LYMPHADENOPATHY by A. V. Sudarkina, A. P. Dergilev, N. A. Gorbunov, V. V. Kozlov, Yu. A. Fokina, I. P. Klimova, P. A. Yagubkin

“…Determination of the genesis of lymphadenopathy is crucial for treatment planning and prognosis of the disease.The purpose of the study was to evaluate the diagnostic accuracy of diffusion weighted imaging (DWI) with apparent diffusion coefficient (ADC) measurements in differentiating malignant versus benign mediastinal lymphadenopathy. Material and Methods. 48 consecutive patients with at least one enlarged mediastinal lymph node revealed on CT-scans were examined on 1,5 T MR-machine with conventional images and respiratory-triggered DWI. …”
Get full text

Proposed Nodal Cancer Index (NCI) in ovarian carcinomatosis by M D Ray, Manish Kumar Gaur

“…Retroperitoneal lymph nodes and bilateral pelvic lymph node dissection were routinely done in all the cases. …”
Get full text

CLASSIFICATION OF PULMONARY METASTASES: POTENTIAL APPLICATION IN CLINICAL PRACTICE by E. I. Smolenov, Yu. A. Ragulin, O. V. Pikin

“…In patients having no lymph node involvement, better results were observed in patients with a solitary site of metastasis (Ms ), with a median survival of 58 months. …”
Get full text

ROLE OF SURGERY IN THE TREATMENT OF SMALL CELL LUNG CARCINOMA by А. А. Aksarin, М. D. Ter-Ovanesov

“…The 5-year survival rate following systematic lymph node dissection was significantly higher than following systematic biopsy (61 % versus 24 %). …”
Get full text

Comparative Diagnostic Value of 18F-FDG–PET–CT and Intraoperative Examination in Cervical Cancer Staging by Goran Malenković, Jelena Malenković, Sanja Tomić, Armin Šljivo, Fatima Gavrankapetanović-Smailbegović, Slobodan Tomić

“…The agreement with histopathological examination was moderate for 18F-FDG–PET–CT and poor for intraoperative examination for lymph node metastasis, highlighting that the overall accuracy of 18F-FDG–PET–CT (82.1%) was significantly higher than that of intraoperative examination (66.1%) (<i>p</i> = 0.002). …”
Get full text

Comparison of microvascular density in cervical carcinoma in relation to predictive pathohistological parameters by Mandić Aljoša, Ivković-Kapicl Tatjana, Gutić Bojana, Maričić Slobodan, Stevanović Nemanja, Šolajić Nenad, Nikin Zoran, Maksimović Tamara, Stevanović Tijana

“…The aim is to analyze microvascular density (MVD) in groups of patients with high grade squamous intraepithelial lesions (H-SIL), and cervical carcinoma, and to compare MVD in relation to the degree of tumor differentiation, size, presence of lymphovascular invasion and lymph node metastases. Materials and methods: The study was retrospective, conducted on histopathological samples of 109 patients who underwent hysterectomy with/without adnexectomy. …”
Get full text

Development and validation of mRNA expression-based classifiers to predict low-risk thyroid tumors by Allan Golding, David Bimston, Emma Namiranian, Ellen Marqusee, Gabriel Correa, Evana Valenzuela Scheker, Ruochen Jiang, Yangyang Hao, Mohammed Alshalalfa, Jing Huang, Joshua P. Klopper, Richard T. Kloos, Sara Ahmadi

“…Here, we developed and validated mRNA-based classifiers with high negative predictive values to preoperatively rule out thyroid tumor invasion and lymph node metastases.Materials and methodsIn this retrospective cohort study, histopathology reports from the Afirma Genomic Sequencing Classifier (GSC) algorithm training and consecutive thyroid cancer patients with Bethesda III–VI thyroid nodules in clinical practice (total 697 and ~50%, respectively) were scored for invasion and metastases. mRNA expression-based classifiers were developed utilizing literature-derived signatures as well as differentially expressed genes between samples with or without clinically significant invasion/metastases as the basic building blocks. …”
Get full text

A Clinical and Pathological Comparison of Different Immunomorphological Subvariants of Nodular Lymphocyte-Predominant Hodgkin’s Lymphoma at Initial Diagnosis by IA Shupletsova, AM Kovrigina, TN Moiseeva, EI Dorokhina, SM Kulikov

“…To study clinical course of NLPHL in patients with different IHC-subvariants of the disease and identify a poor prognosis subgroup. Materials & Methods. From 2010 to 2017 the Department of Anatomic Pathology at the National Medical Hematology Research Center undertook morphological and IHC-analysis of lymph node and bone marrow core biopsies of 60 NLPHL patients: 47 men and 13 women (male/female ratio of 3.6:1) aged 17–68 years (median 37 years). …”
Get full text

Does adenomyosis influence tumor characteristics and survival in endometrioid-type endometrial cancer?? by Gorkem Ulger, Sevki Goksun Gokulu, Kasim Akay, Hamza Yildiz, Ali Yildizbakan, Tolgay Tuyan Ilhan, Hakan Aytan

“…Similarly, rates of myometrial invasion (81.3% vs. 65.5%, p = 0.001), cervical stromal invasion (9.0% vs. 14.1%, p = 0.005), and lymph node metastasis (4.2% vs. 14.4%, p = 0.001) were significantly lower in patients with adenomyosis. …”
Get full text

Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion following Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer: An Initial Experience by Tünkut Doğanca, Ömer Burak Argun, Mustafa Bilal Tuna, İlter Tüfek, Can Öbek, Ali Rıza Kural

“…Materials and Methods: A total of 14 patients underwent neoadjuvant chemotherapy for invasive bladder tumors, followed by robot-assisted radical cystectomy, extended lymph node dissection, and intracorporeal urinary diversion. …”
Get full text

Hormone receptor status (estrogen receptor, progesterone receptor), human epidermal growth factor-2 and p53 in South Indian breast cancer patients: A tertiary care center experienc... by Rashmi Patnayak, Amitabh Jena, Nandyala Rukmangadha, Amit Kumar Chowhan, K Sambasivaiah, Bobbit Venkatesh Phaneendra, Mandyam Kumaraswamy Reddy

“…We have undertaken this study with the aim to evaluate the ER, PR, HER-2 and p53 expressions in invasive breast carcinomas by IHC and to compare the HER-2 expression with various clinicopathological parameters. Materials and Methods: In this retrospective single institutional study from January 2001 to December 2010, 389 cases of histopathologically diagnosed infiltrating carcinoma of breast were evaluated taking into account various parameters like age, tumour size, grade, lymph node involvement, ER and PR. …”
Get full text

Evaluation of Kynu, Defb2, Camp, and Penk Expression Levels as Psoriasis Marker in the Imiquimod-Induced Psoriasis Model by Zahra Emami, Saeideh Sadat Shobeiri, Razia Khorrami, Navideh Haghnavaz, Mohammad Ali Rezaee, Malihe Moghadam, Safoora Pordel, Mojtaba Sankian

“…In order to assess the systemic response, the spleen and lymph node indexes were also evaluated. Results. …”
Get full text

Crowding phenomenon in breast cancer as a prognostic factor by N. V. Krakhmal, M. V. Zavyalova, S. V. Vtorushin, L. A. Tashireva, V. M. Perelmuter

“…The phenomenon of crowding in breast cancer was shown to be associated with lymph node metastases, with intratumoral heterogeneity of particular importance. …”
Get full text

Clinical Presentation of Malignant Tumours of Tonsil and its Association with Unilateral Enlarged Tonsil in Different Age Groups by Tallat Najeeb, Raja Muhammad Shoaib, Nayyer Ayub

“…Results: In group I predominant symptom was bilateral (B/L) cervical lymph node enlargement, 32(82%) along with UET. Majority of patients (82.5%) with clinically enlarged tonsil also showed enlargement in gross. …”
Get full text

Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer by A. A. Skorokhod, A. S. Petrov, A. R. Kozak, M. A. Atyukov, A. O. Nefedov, P. K. Yаblonskiy

“…The average number of remote lymph node stations in group 1 was (7.8±1.7); in group 2 – (4.5±1.2) (p&lt;0.05). …”
Get full text

Steroid versus antituberculosis treatment: Minimizing side effects through accurate diagnosis – The role of endobronchial ultrasound in differentiating pulmonary tuberculosis from... by Srishankar Bairy, Don Gregory Mascarenhas, Archana Bhat, Anna Rose Roy, Eldhos Jacob, M. Meghana

“…EBUS facilitates safe and accurate sampling of mediastinal lymph nodes, enabling histological confirmation. …”
Get full text

The Role of Ultrasound as a Predictor of Malignancy in Indeterminate Thyroid Nodules—A Multicenter Study by Reem J. Al Argan, Dania M. Alkhafaji, Feras M. Almajid, Njoud K. Alkhaldi, Zahra A. Al Ghareeb, Moutaz F. Osman, Manal A. Hasan, Safi G. Alqatari, Abrar J. Alwaheed, Fatima E. Ismaeel, Reem S. AlSulaiman

“…Solid hypoechoic nodules showed 82.3% specificity and 63.0% positive predictive value (PPV); microcalcifications demonstrated 84.1% specificity and 68.4% PPV; lymph node involvement had 87.6% specificity and 68.9% PPV. …”
Get full text

Metastatic synovial sarcoma: Experience from a tertiary care center from India by K Govind Babu, Rajesh Patidar, C Lakshmaiah Kuntegowdanahalli, Lokanatha Dasappa, Linu Abraham Jacob, Suresh Babu, A H Rudresha, Lokesh N Kadabur, L K Rajeev, Deepak Koppaka, Vikas Asati

“…The most common site of metastasis is the lungs, lymph nodes followed by bones. Ifosfamide-based chemotherapy is associated with improved outcome. …”
Get full text