GENERAL AND SPECIFIC STRUCTURAL CHANGES OF LYMPHOID ORGANS IN THE HIGH DOSE APPLICATION OF SODIUM SELENITE by I. Putalova, O. Zayko, A.Sindireva, O. Grinenko, I. Kosheleva

“…The morphometric research of the thymus, group lymphoid nodules, mesenteric lymph nodes, spleen, and laboratory investigation of blood were performed. …”
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Consensus process to agree upon surgical quality assurance processes within a pragmatic, multicentre randomised clinical trial comparing targeted axillary dissection and axillary n... by Stuart A McIntosh, Kirsty Roberts, Lucy Culliford, Natalie S Blencowe, Kerry Avery, Jessica Harris, Shelley Potter, Sophie Rees, Yazan Masannat, Peter Barry, David Dodwell, Elsa Marques, James R Harvey, Jocelyn Lippey, Margaret Perkins, Adrienne Morgan, Katherine Fairhurst, Petra Baji, Ramsey Cutress, G Bruce Mann, Jessica Frost, Ruth Mullan, Henry Cain, Edward St John, Indrani Bhattacharya, Hannah Markham

“…Evidence that this highly morbid procedure improves survival is lacking, but approximately 30% of patients will develop lifelong complications which significantly impact their quality of life.Targeted axillary dissection (TAD) may be a safe, less morbid alternative to ANC and will be evaluated in the upcoming Targeted Axillary Dissection versus axillary node clearance in patients with POsitive axillary Lymph nodes in Early breast cancer (TADPOLE) randomised controlled trial.TAD is not currently routine practice in patients having primary surgery, so it is vital that the procedure is performed in an agreed upon, standardised way within the trial and procedure fidelity monitored to ensure the results are generalisable and will be accepted by the surgical community. …”
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Uterine sarcoma: the possibility of modeling a rare tumor and providing its morphological description by E. M. Frantsiyants, A. I. Shikhlyarova, I. V. Neskubina, I. V. Kaplieva, L. K. Trepitaki, V. A. Bandovkina, Yu. A. Pogorelova, E. I. Surikova, T. I. Moiseenko, N. D. Cheryarina, E. R. Tolmakh, A. A. Vereskunova, O. G. Ishonina, E. V. Verenikina, A. P. Menshenina

“…Unlike subcutaneous grafting of sarcoma M1, the tumor growing in the uterine horn was characterized by the presence in the abdominal cavity of many nodules and tumor dropouts on the mesentery, i. e. lymph nodes. According to the cellular composition, tumors formed from a suspension of M1 sarcoma cells injected into the right horn of the uterus were characterized by a polymorphocellular type of structure against the background of pronounced neoangiogenesis. …”
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Development and immunobiological evaluation of nanoparticles containing an immunodominant epitope of herpes simplex virus by Gabriel M. Hilario, Fernando B. Sulczewski, Raquel Liszbinski, Larissa D. Mello, Gustavo Hagen, Tiago Fazolo, Jayme Neto, Eliane Dallegrave, Pedro Romão, Tanira Aguirre, Luiz C. Rodrigues Junior

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Diagnostic and prognostic significance of detecting mutations in the <i>BRAF, TERT, RAS, RET/PTC, PAX8/PPARG</i> in the material of fine needle aspiration biopsy thyroid nodules in... by A. A. Musaelyan, S. V. Lapin, V. D. Nazarov, E. S. Kozorezova, S. L. Vorobyev, S. V. Orlov

“…The prevalence of mutations in benign formations was 4.7 %. mutations in RAS genes were also found in them in group 1, mutation BRAF V600E was associated with the presence of extrathyroid invasion (p = 0.024), vascular invasion (p = 0.018), and lymph node metastases (p = 0.018). In group 2, using the genetic panel sensitivity and specificity were equal: 36.4 and 93.9 %, respectively. positive and negative predictive values were 66.7 and 81.6 %, respectively. …”
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Liposomal structure tuned J-aggregated ICG as enhanced NIR-II imaging nanoprobe by Haoli Yu, Yuesong Wang, Yan Chen, Mengyuan Cui, Huiting Xu, Yang Liu, Mingxi Li, Min ji, Fang Yang

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NIR light-driven transformable liquid metal-based nanovaccines restrain postoperative colorectal cancer recurrence by Zheng Dai, Feng Liu, Miaodeng Liu, Yuqi Song, Hongyan Zhang, Cheng Zhou, Wenyu Liu, Xiaoqiong Li, Guobin Wang, Lin Wang, Zheng Wang

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Fabrication and functional validation of a hybrid biomimetic nanovaccine (HBNV) against KitK641E-mutant melanoma by Kishwor Poudel, Zhenyu Ji, Ching-Ni Njauw, Anpuchchelvi Rajadurai, Brijesh Bhayana, Ryan J. Sullivan, Jong Oh Kim, Hensin Tsao

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α-GalCer-LNP ehanced mRNA delivery and activates natural killer T cells for superior tumor immunotherapy by Kexin Zhang, Zhen Xu, Zexiu Xiao, Fei Cao, Jing Wang, Yuandong Xu, Winson M.J. Ma, Sihui Long, Gao-Feng Zha

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Mitochondria-targeted photothermal-chemodynamic therapy enhances checkpoint blockade immunotherapy on colon cancer by Benchao Zheng, Hongbo Wang, Shiyi Zhai, Jiangsheng Li, Kuangda Lu

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Correlation of Histological Grading with Regional Metastasis in Oral Squamous Cell Carcinoma – A Cross-Sectional Study by Ruchita Patel, Kavan Patel, Rohit Mehta, Anshit Babel, C Nandini, Mahendrakumar A. Chaudhari, Dhaval Niranjan Mehta

“…A bad prognosis for mouth cancer is indicated by cervical lymph node metastases. There is a correlation between lymph node metastases and TNM staging, Broder’s grading system, and Anneroth grading system. …”
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Tumour budding in invasive ductal breast carcinomas: correlation with clinicopathological prognostic parameters and hormone receptor status by Sachin Sebastian Francis, Swati Sharma

“…Univariate and multivariate logistic regression analyses were also done to demonstrate the significance of association.ResultsHigh-grade PTB showed significant associations with LVI (p = 0.046), PNI (p = 0.017), and axillary lymph node involvement (p = 0.021). In contrast, high-grade ITB was only significantly correlated with axillary lymph node involvement (p = 0.044). …”
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Nomograms for predicting the prognosis in multiple primary esophageal squamous cell carcinoma by Kexi Wang, Jian Zhong, Danting Su, Changsen Leng, Jianhua Fu, Qianwen Liu

“…In addition, we further evaluated the effect of postoperative adjuvant therapy on SMPESCs patients with lymph node metastasis.Results In univariate and multivariate analyses of DFS and OS, age, site of the main lesion, lymph node metastasis, total number of lymph nodes dissected, lactate dehydrogenase level and lymphocyte-to-monocyte ratio were identified as independent prognostic factors. …”
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CAUSE OF RELAPSE GASTRIC CANCER PATIENTS AFTER RADICAL TREATMENT by A. G. Baryshev, V. A. Porhanov, A. Y. Popov, A. N. Lishenko, N. V. Hachaturyan, D. A. Valyakis, M. V. Bodnya

“…Material and methods. Using the Kaplan-Meier method and analysis of variance, long-term treatment outcomes were analyzed in 662 patients with gastric cancer, who underwent either limited/standard lymph node dissection (D1) or extended lymph node dissection (D2). …”
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Endoscopic surgery for papillary thyroid microcarcinoma: cases review and investigation of technique dissemination in China by Yinghui Liang, Shuangta Xu

“…The most frequently questioned issues regarding the trans-breast and trans-axillary approaches were the completeness of central lymph node dissection (with 66.78% and 40.46% of respondents, respectively, considering the lymph node dissection to be incomplete). …”
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Adenoid cystic carcinoma of head and neck: A single institutional analysis of 66 patients treated with multi-modality approach by Ajeet Kumar Gandhi, Soumyajit Roy, Ahitagni Biswas, Suman Bhasker, Atul Sharma, Alok Thakar, Bidhu Kalyan Mohanti

“…Conclusion: Surgery followed by adjuvant radiotherapy remains the treatment of choice for HN ACC. Lymph node involvement and ICE confer poor prognosis.…”
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Relevance of Platelet-lymphocyte Ratio in Tumor Characteristics and Survival in Clear Cell-renal Cell Carcinoma by Santhosh Srinivasan, Poulose Chally, Abdul Azeez, Pankaj Bhirud

“…PLR shown a strong link with both renal vein invasion (P = 0.029) and lymph node metastasis (P < 0.001) in our study, after being compared to tumor size, Fuhrman’s grading, metastasis-free survival, and lymph node metastasis. …”
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Neurosarcoidosis. Difficulties of diagnosis by L. Kh.-B. Akhmatkhanova, E. V. Shevchenko, A. G. Gutsalyuk, D. V. Burenchev, G. R. Ramazanov

“…Brain MRI revealed leptomeningeal enhancement of the contrast agent. Lymph node biopsy confirmed granulomatous lymphadenitis characteristic of sarcoidosis. …”
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LEVELS I–VII FOLLOWING THYROIDECTOMY FOR PAPILLARY THYROID CANCER by V. S. Parshin, A. A. Veselova, V. S. Medvedev, S. A. Ivanov, A. D. Kaprin

“…The aim of this study was to assess the potential utility of neck ultrasound in diagnosing cervical lymph node metastases (levels I–VII) in patients who underwent surgical treatment for papillary thyroid cancer.Material and Methods. …”
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Computed Tomography Imaging Characteristics in the Diagnosis and Assessment of Cellulitis in Patients with Leg Swelling by In-Chul Nam, Doo-Ri Kim, Jeong-Sub Lee, Jeongjae Kim, Young-Heun Shin, Jung-Ho Won, Yong-June Lee

“…The qualitative CT features analyzed included skin thickening (83.9%), subcutaneous edema (94.8%), early venous return (82.8%), lymph node pathological findings (72.4%), and prominent lymph node enhancement (79.3%). …”
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