Innovative gene delivery systems for retinal disease therapy by Hongguang Wu, Ling Dong, Shibo Jin, Yongwang Zhao, Lili Zhu

“…Gene delivery systems hold great promise for treating retinal diseases by enabling the targeted delivery of therapeutic genes to affected cells or by converting endogenous cells into functional ones to facilitate nerve regeneration, potentially restoring vision. …”
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Structural and optical characterization of TiO2 nanoparticles synthesized using Globularia alypum leaf extract and the antibacterial properties by Hanen Sellami, Muiz O. Akinyemi, Maroua Gdoura-Ben Amor, Damian C. Onwudiwe, Doctor M. N. Mthiyane

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PET imaging of GABAA receptors in pancreatic islets by [11C]flumazenil by Faïza Maloum-Rami, Pierre Cheung, Gunnar Antoni, Zhe Jin, Olof Eriksson, Daniel Espes

“…There are no clinically established methods for quantifying endocrine cells of the pancreas and current knowledge is almost exclusively based on autopsy material and functional measurements. Based on the expression of the γ-aminobutyric acid A receptors (GABAARs) in pancreatic islets and the fact that GABAAR agonists are being explored as treatment for T1D, we hypothesized that the positron emission tomography (PET) tracer [11C]flumazenil ([11C]FMZ) could serve as a marker of the endocrine mass of the pancreas. …”
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Acute nitroglycerin test for predicting perindopril therapy effectiveness in patients with coronary heart disease and chronic heart failure by I. G. Fomina, N. A. Galanina, Z. O. Georgadze, N. E. Gaidamakina

“…By ejection fraction (EF) figures, all participants were divided into two groups: Group I consisted of 89 patients with CHD an Functional Class (FC) II-III CHF, LVEF>40%; Group II included 38 CHD patients with FC III-IV CHF, LVEF<40%. …”
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Pedagogical management in the digital educational environment: Theoretical aspect by S. S. Kulikova, O. V. Yakovleva

“…The novelty of the research lies in the systemic understanding of the category of pedagogical management in the new digital conditions; in the system-functional description of the digital educational environment management model. …”
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Recurrence of atrial fibrillation and late cardiovascular events in patients with persistent atrial fibrillation after restoration of sinus rhythm by U.P. Chernyaha-Royko, N.S. Pavlyk, M.S. Sorokivskyy, A.V. Aker, O.J. Zharinov

“…Demographic and clinical-functional features, data of event monitoring (EV) for 7 days and Holter monitoring (HM ECG), treatment were compared in groups of patients with (n = 15) and without (n = 105) events. …”
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Lipid-Polymer Hybrid Nanoparticles as a Smart Drug Delivery System for Peptide/Protein Delivery by Alharith A. A. Hassan, Eslam Ramadan, Katalin Kristó, Géza Regdon, Tamás Sovány

“…Recently, lipid-polymer hybrid nanoparticles (LPHNs) have emerged as an advanced solution combining the structural stability of polymers and the biocompatibility and surface functionalities of lipids to enhance the controlled release, stability, and bioavailability of protein and peptide drugs. …”
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MiR-494-3p knockdown promotes osteogenic differentiation of bone marrow mesenchymal stem cells in ovariectomised rats by targeting Sirt1/TLR4/NF-κB pathway by Jianping Lei, Song Guo, Jiabing Kuang, Bo Shen, Zixi Li

“…RESULTS: MiR-494-3p level was upregulated, and Sirt1 mRNA and protein levels were downregulated, in femurs of OVX rats. Functionally, miR-494-3p inhibited osteogenic differentiation of cultured rat BMSCs. …”
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Optical coherence tomography in preclinical diagnosis of optic nerve disk changes after chemotherapy in children with retinoblastoma by S. V. Saakyan, E. B. Myakoshina, V. G. Polyakov, T. L. Ushakova, D. M. Ismailova

“…Preclinical diagnostics of optic disc pathology with the help of OCT allows predicting visual functions in children with RB at its early stages and developing a differentiated approach to the choice of RB treatment.…”
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INTERACTION BETWEEN SYMPATHO-ADRENAL ACTIVITY AND IMMUNE MEDIATORS IN PATIENTS WITH METABOLIC SYNDROME by N. R. Uzbekova, M. A. Khuzhamberdiev, I. M. Tashtemirova

“…To investigate the interactions between the functional status of sympatho­adrenal system and immune meditators in patients with metabolic syndrome (MS).Material and methods. …”
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Azov-type spits: long-term monitoring of morphodynamics and vegetation in response to changing environment by Oksana Tyshchenko, Volodymyr Tyshchenko, Svitlana Boychenko, Andrii Tarieiev, Vasyl Tkachenko

“…These factors significantly shape the ATS, influencing their capacity to accumulate biogenic material and sediments, thereby impacting vegetation cover, resilience and functioning within their ecological context. …”
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A systematic literature review of the theoretical foundations of therapeutic and recuperative approaches through physiatry interventions involving prism adaptation in unilateral sp... by Roxana Bistriceanu, Aurelian Anghelescu, Gelu Onose

“…This syndrome significantly impacts the individual's quality of life and level of functionality. Several rehabilitative interventions have been designed to enhance or resolve USN, with prism adaptation gaining increased focus in recent years. [4] The study aims to emphasize the therapeutic effects of Prism Adaptation Therapy (PAT) in addressing Spatial Neglect (SN) following brain damage. …”
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The effectiveness of trimetazidine and fabomotizole in the prevention of angina progression and improvement of life quality in patients in area of armed conflict by Z. Yu. Shakhbiyeva, A. A. Abdullaev, U. A. Isiamova, D. D. Abdulpatakhov, A. A. Abdullaeva

“…To assess the effectiveness of trimetazidine and fabomotizole adding to standard treatment in prevention of stable angina progression and improving of quality of life (QOL) in patients in area of armed conflict.Material and methods. One hundred and twelve patients with stable angina of II-III functional class (FC) living in the area of armed conflict in Chechen Republic. …”
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Thromboembolic risk factors and predictors of left atrial appendage thrombosis in Far North patients with nonvalvular atrial fibrillation by N. Yu. Khorkova, T. P. Gizatulina, A. V. Belokurova, E. A. Gorbatenko, E. I. Yaroslavskaya

“…Compared to patients living in the temperate latitudes, Far North patients were younger (p=0,021) and were more likely to have type 2 diabetes (14,2% vs 8,3%, p=0,022), class ³II obesity (29,6% vs 21,1%, p=0,019), persistent AF(47,5% vs 33,2%, p=0,0019), LAA thrombosis (13% vs 6,6%, p=0,006), and severe structural and functional cardiac abnormalities (biatrial and right ventricular enlargement, lower left ventricular ejection fraction). …”
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ALGORITHM FOR EARLY CANCER DETECTION IN CHILDREN by M. Yu. Rykov, O. A. Manerova, I. A. Turabov, V. V. Kozlov, V. A. Reshetnikov

“…The introduction of a structural and functional model for organizing medical care for children with cancer was shown to be effective.…”
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Global Transcriptome and Correlation Analysis Reveal Cultivar-Specific Molecular Signatures Associated with Fruit Development and Fatty Acid Determination in Camellia oleifera Abel by Shaofeng Peng, Jia Lu, Zhen Zhang, Li Ma, Caixia Liu, Yongzhong Chen

“…We attempt to identify genes related to fatty acid biosynthesis in an oil-tea Camellia seed kernel, generated a comprehensive transcriptome analysis of the seed kernel at different developmental stages, and explore optimal picking time of fruit. Material and Methods. A gas chromatography-mass spectrometer was used to detect the content of various fatty acids in samples. …”
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Low levels of adropin are associated with acute kidney injury after decongestion in patients with acutely decompensated heart failure by Alexander E. Berezin, Tetiana A. Berezina, Evgen V. Novikov, Oleksandr O. Berezin

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BLOOD LIPOPROTEINS AS A PLATFORM FOR TRANSPORT OF HYDROPHILIC AND HYDROPHOBIC COMPOUNDS by L. M. Polyakov, R. A. Knyazev, A. V. Ryabchenko, M. V. Kotova, N. V. Trifonova

“…The paper discusses the transport functions of the main classes of blood plasma lipoproteins (LP) that are not associated with the metabolism of lipids that make up their composition. …”
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Research on the Characteristics of Electrolytes in Integrated Carbon Capture and Utilization Systems: The Key to Promoting the Development of Green and Low-Carbon Technologies by Guoqing You, Yunzhi Li, Lihan Dong, Yichun Li, Yu Zhang

“…Ionic liquids (ILs) demonstrate unique advantages due to their tunability: imidazolium-based ILs improve formate selectivity to 85% via carboxylate intermediate formation, while amino-functionalized task-specific ILs (TSILs) achieve a 1:1 stoichiometric CO₂ absorption ratio. …”
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Phygitalization of educational technologies in Russia: directions, examples, problems by Andrey I. Kapterev

“…Phygital (physical + digital) is a complex of technologies where students get a unique interactive experience using both traditional material sources of educational information and virtual communication in the educational process. …”
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