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25541
E. coli Endotoxin Modulates the Expression of Sirtuin Proteins in PBMC in Humans
Published 2013-01-01“…Sirtuin (SIRT) proteins are class I histone deacetylases displaying gene regulatory functions in inflammatory, cancer, and metabolic diseases. …”
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25542
The smart city concept as a method of building urban resilience to threats: Evidence from Poland
Published 2025-07-01“…Objectives The functioning of cities is strongly influenced by local phenomena and global processes related to the urban natural environment. …”
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25543
Chloroplast Vesiculation and Induced Chloroplast Vesiculation and Senescence‐Associated Gene 12 Expression During Tomato Flower Pedicel Abscission
Published 2025-01-01“…This suggests a possible vesicle transport of chloroplast degrading material for recycling by autophagy‐independent senescence‐associated vacuoles (SAVs) and CV‐containing vesicles (CCVs). …”
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25544
Impact of Laparoscopic Sleeve Gastrectomy on Gastrointestinal Motility
Published 2018-01-01“…The stomach motility was assessed in eighteen studies. Functionally, the sleeve was divided into a passive sleeve and an accelerated antrum. …”
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25545
Fruits of Polish Medicinal Plants as Potential Sources of Natural Antioxidants: Ellagic Acid and Quercetin
Published 2025-05-01“…The research material was chosen considering both the popularity of the fruits and their recognized medicinal and pharmaceutical properties. …”
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25546
Achieving significant mechanical improvement of chitosan aerogel with embedding or bridging structures mediated by size-dependent silk microfibers
Published 2025-05-01“…The results of this study demonstrated the feasibility of applying filler-size-mediated strategy for material structural optimization.…”
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25547
Life cycle assessment of additively manufactured elastocaloric Ni-Ti heat pump/refrigeration components and the effect of design geometry on the environmental impact categories
Published 2024-12-01“…A 10 x 10 × 55 mm Ni-Ti structure, providing >2 °C temperature span under compressive cycles, served as the functional unit.…”
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25548
Evaluation of Regeneration Effects of Different Rejuvenators on Aged Asphalt
Published 2025-04-01“…As a polymer-like organic material, asphalt often undergoes aging during service life. …”
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25549
Retrospective Evaluation of Tooth Agenesis in Different Regions of Turkey with Panoramic Radiography
Published 2025-01-01“…It can result in several complications, impacting functional aspects of the dentition, such as chewing and speech. …”
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25550
Research on Mechanical Performance of Porous Asphalt Mixture with High-Viscosity Modified Asphalt
Published 2025-03-01“…The proposed high-viscoelastic asphalt formulation meets the technical requirements for functional drainage asphalt mixtures while providing material-level support for implementing sponge city initiatives.…”
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25551
CD44-Receptors-Mediated Multiprong Targeting Strategy Against Breast Cancer and Tumor-Associated Macrophages: Design, Optimization, Characterization, and Cytologic Evaluation
Published 2025-01-01“…In this research, we aimed to design a multiprong targeting strategy for concurrent action against different phenotypes of BC (MCF-7 and SK-BR-3) and tumor-associated macrophages (TAMs) for relapse-free treatment of BC.Methods: Paclitaxel (PTX) and tamoxifen (TMX) co-loaded chitosan (CS) nanoparticles (NPs) were prepared using the ionic-gelation method and optimized using the Design Expert® software by controlling different material attributes. For selective targeting through CD44-receptors that are heavily expressed on the BC cells and TAMs, the fabricated NPs (PTX-TMX-CS-NPs) were functionalized with hyaluronic acid (HA) as a targeting ligand.Results: The optimized HA-PTX-TMX-CS-NPs exhibited desired physicochemical properties (PS ~230 nm, PDI 0.30, zeta potential ~21.5 mV), smooth spherical morphology, high encapsulation efficiency (PTX ~72% and TMX ~97%), good colloidal stability, and biphasic release kinetics. …”
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25552
PRAGMATIC DEVIATIONS IN TRANSLATION OF LEXICAL BLENDS WITHIN POLITICAL DISCOURSE
Published 2023-12-01“…The general and special methods were used to achieve the goal and objectives of the study: information retrieval method – to select research material and process basic theoretical knowledge; generalization method – to highlight the most critical academic positions; deduction and induction – to clarify the theoretical foundations, generalize data and formulate conclusions; discourse analysis – to identify specific communicative and pragmatic features of socio-political communication; contextual and functional methods – to actualize the linguopragmatic meaning of the lexical units under the study, i.e., blends; the vocabulary definitions analysis – to examine their linguopragmatic peculiarities; structuralsemantic and component analysis – to determine the ways of blend formation and their main structural elements – all this is necessary for the implementation of translation analysis. …”
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25553
Model of property relations in the Soviet Lithuania village (Case of Stungiai village)
Published 2004-12-01“…Good execution of a task corresponded to bigger volume of material resources used and smaller amount of tasks received. …”
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25554
The impact of local symptoms on health‐related quality of life in vulvar cancer survivors—A nationwide prospective study
Published 2025-08-01“…Emotional‐, role‐, social‐, and cognitive functioning, global and mental health improved significantly after treatment. …”
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25555
DIABETES MELLITUS 2ND TYPE WITH CARDIOVASCULAR AUTONOMIC NEUROPATHY
Published 2015-09-01“…To perform the analysis of some parameters of insulin resistance, concentration of N-terminal natriuretic pro-brain peptide (NT-prоBNP), hi-sensitive С-reactive proteine (hsCRP) and some proand anti-inflammatory cytokines in diabetes mellitus patients with diabetes mellitus 2nd type (DM2) with cardiovascular autonomic neuropathy (CAN).Material and methods. Totally 48 patients studied with DM2, of those 12 without verified cardiovascular diseases (CVD), 36 patients with functional stage of CAN, age 50-59 y., DM2 1-6 y. duration, HbA1c 7,1±0,6%. …”
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25556
Extracorporeal shockwave therapy as a treatment option for shoulder impingement syndrome: a systematic review and meta-analysis
Published 2025-07-01“…Abstract Background Shoulder impingement syndrome (SIS) is a common alignment syndrome that causes significant discomfort and functional limitations. In recent years, extracorporeal shock wave therapy (ESWT) has gained attention as a promising non-invasive treatment for SIS. …”
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25557
Methylation of p53-responsive oncosuppressive microRNA genes in hemoblastosis
Published 2022-05-01“…The review examines the molecular and genetic characteristics of oncosuppressive micrornas functioning in normal hematopoiesis, the violation of expression of which is shown in the development of hemoblastoses, namely: miR-34a, miR-34b/c, miR-145, miR-143 and miR-203. …”
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25558
Retalho supramaleolar de fluxo reverso: aplicações clínicas Supramalleolous flap of reverse flow: clinical applications
Published 2011-03-01“…Donor areas are larger, can cause functional impairment and use on major vascular trunks. …”
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25559
Pharmacoeconomic analysis of the use of tocilizumab in therapy for rheumatoid arthritis:imitation simulation
Published 2010-04-01“…Modeling relied on the relationship of RA mortality to a patient's functional status rated by the health assessment questionnaire (HAQ). …”
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25560
The significance of notch signaling in the regulation of Тreg-lymphocyte differentiation in patients with infiltrative pulmonary tuberculosis
Published 2023-06-01“…The overwhelming effect of Treg cells on the proliferation, functional activity of Th1 lymphocytes and antigen-presenting cells allows to consider this population as a possible target of modulation of the immune response in patients with tuberculosis. …”
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