EVALUATION OF THE ROLE OF HYPERHOMOCYSTEINEMIA AND POLYMORPHISM C677T GENE OF METHYLTETRAHYDROFOLATEREDUCTASE IN DEVELOPMENT OF CHRONIC HEART FAILURE by A. T. Teplyakov, E. N. Berezikova, S. N. Shilov, E. V. Grakova, Yu. Yu. Torim, A. V. Efremov, А. А. Popova, М. G. Pustosvetova, А. Yu. Sabirova, К. V. Kopieva

“…To study the influence of polymorphism of the gene methyltetrahydrofolate-reductase (MTHFR) — polymorhic locus С677Т, and level of homocysteine  in blood plasma on the risk of development and course of chronic heart failure (CHF).Material and methods. Totally, 277 persons  studied  with CHF II-IV functional classes (FC NYHA). …”
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Comparing effectiveness of adding prolonged trimetazidine or isosorbide dinitrate to beta-adrenoblocker therapy in stable angina patients by M. G. Glezer, M. V. Novikova, I. V. Kiseleva, R. T. Saigitov

“…To study effects of adding isosorbide dinitrate (ID) and trimetazidine MB 35 mg (Tr) to beta-adrenoblocker therapy in stable angina (SA) patients. Material and methods. In total, 40 patients with Functional Class II-III SA were examined. …”
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Formation of Research Vision in Schoolchildren Using Digital Mediation Tools according to Cultural-Historical Psychology. Part 1 by E.N. Pavlovsky, T.A. Sidorova, S.A. Smirnov, B.N. Tuchinov

“…The project sets the task of forming a research vision (a new functional organ) in schoolchildren with the help of digital mediating tools. …”
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Optimizing the Coating for Masking Conditions Process with Gum Arabic Using Box-Behnken Design (BBD) on The Properties of Masked Spirulina Powder by Prasetiyo Himawan, Purwaningsih Sri, Setyaningsih Iriani, Uju, Nurilmala Mala, Tarman Kustiariyah

“…The coating for masking process is carried out to maintain functional properties of food product. Gum Arabic (GA) is a natural polysaccharide which can be used as a masking material in commercial food. …”
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Biosynthesized ZnO Nanoparticles using Rivea Hypocrateriformis Pant Extract Assisted for Photocatalytic Activity in the Treatment of Wastewater by Murugesan Balaji, Pattulingam Rajesh, Sathasivam Kavica, Nagarajan Vignesh

“…These days, a material with antimicrobial and photocatalytic activity is highly needed due to the developing problem of water contamination by wastewater released from the expanding paper, ink, leather, and textile industries as well as provides with disease-causing pathogenic microorganisms. …”
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An integrated widely targeted metabolomics and network pharmacology study of Persicaria runcinata var. Sinensis against arthritis by Zengcai Liang, Xifeng Chen, Yunrong Xie, Feiyan He, Linlin Zhang, Xiang Zhu, Taofeng Lu

“…Abstract The present study aimed to investigate the material basis of Persicaria runcinata var. sinensis (Hemsl.) …”
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Establishing meaningful change thresholds for European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire CLL‐specific module domain scores: An analysi... by Laurie Eliason, Fatoumata Fofana, Lin Wang, Peter A. Riedell, Shien Guo

“…Abstract Introduction The study aimed to establish meaningful thresholds at patient and group levels for the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire CLL‐specific module (EORTC QLQ‐CLL17) domain scores in adults with relapsed or refractory (R/R) chronic lymphocytic leukaemia (CLL). Material and methods Data for the analysis were from the TRANSCEND CLL 004 study (NCT03331198). …”
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Gastrointestinal distribution and in vitro-microbial biotransformation of chlorogenic acid by Yunhui Zhang, Bowei Zhang, Xiaoxia Liu, Xiang Li, Fan Wei, Lingda Zhao, Huan Lv, Xudong Wang, Jin Wang, Jing Wu, Yan Zhang, Shuo Wang

“…Chlorogenic acid (CGA), as a polyphenol abundant in daily diet, exerted various intestinal functions. However, the material basis of its intestinal bioactivities was still unclear. …”
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Long-term dental follow-up in hematological stem cells transplantation children by Luiz Alberto Valente Júnior, Paulo Sérgio da Silva Santos, Fabio Luiz Coracin, Alexandre Viana Frascino, Marcelo Fava, Vicente Odone Filho

“…Conclusion: The late effects of craniofacial development disturbances leads to several aesthetic and functional impairment, periodontal bone resorption with consequent impairment of chewing ability, and risk of early tooth loss often associated with life’s quality impairment. …”
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Treatment of orbital floor fracture with conchal cartilage by Waldemar Chaves Nascimento Brandao Penna, Isabel Camilo de Oliveira, David Santiago Ordonez Arízaga, Marco túlio Ribeiro Peixoto Ferreira, Márcio Henrique Lima Resende, Gustavo Moreira Costa de Souza, Sérgio Moreira da Costa, Klaus Rodrigues de Oliveira

“…INTRODUCTION: The reconstruction of defects in the orbital floor after fractures poses a challenge to the plastic surgeon because besides the patient's aesthetic and reconstructive expectations, possible functional complications such as diplopia and facial paresthesia must be treated. …”
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Cell Adhesion on Polycaprolactone Modified by Plasma Treatment by Nina Recek, Matic Resnik, Helena Motaln, Tamara Lah-Turnšek, Robin Augustine, Nandakumar Kalarikkal, Sabu Thomas, Miran Mozetič

“…The PCL scaffolds were treated in plasmas created in O2, NH3 or SO2 gas at identical conditions. Surface functionalization of plasma-treated samples was determined using X-ray photoelectron spectroscopy. …”
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Effects of fermented Arctium lappa L. root by Lactobacillus casei on hyperlipidemic mice by MingJu Chen, Yuxiao Wu, Hongxuan Yang, Tianfeng Liu, Tongkun Han, Wangqiang Dai, Junyue Cen, Fan Ouyang, Jingjing Chen, Jianxin Liu, Lin Zhou, Xuguang Hu

“…It also improved liver injury as well as better regulation of lipid levels, pro-inflammatory cytokine levels, and cholesterol-related mRNA. 16S rRNA analysis revealed that LC-AR decreased the Firmicutes/Bacteroidetes ratio, which correlated negatively with triglycerides, total cholesterol, and low-density lipoprotein cholesterol levels.DiscussionThese findings suggest that LC-AR may serve as a promising functional food and drug raw material for improving hyperlipidemia, particularly through its beneficial effects on gut microbiota and lipid regulation.…”
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Surgical outcomes of lamellar macular holes treatment using autologous platelet-rich plasma by D.O. Shkvorchenko, O.Yu. Vedernikova, A.A. Shpak

“…To evaluate the results of surgical treatment of lamellar macular holes (LMH) using autologous platelet-rich plasma (PRP) in comparison with the standard surgical technique. Material and methods. The study included 71 patients (71 eyes) with LMH. …”
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COMPARISON OF THE LIFE QUALITY WITH MECHANICAL AND BIOLOGICAL MITRAL PROSTHESES by N. V. Rogulina, E. V. Gorbunova, N. V. Kondyukova, Yu. N. Odarenko, L. S. Barbarash

“…There were no differences between the groups in social functioning assessment.Conclusion. The usage of bioprosthesis in mitral valve defect increases LQ parameters. …”
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Inhibition of matrix metalloproteinases: a troubleshooting for dentin adhesion by Izadora Quintela Souza de Moraes, Ticiano Gomes do Nascimento, Antonio Thomás da Silva, Lilian Maria Santos Silva de Lira, Abhishek Parolia, Isabel Cristina Celerino de Moraes Porto

“…The knowledge about MMPs functionality should be considered to synthesize drugs capable to efficiently and selectively block MMPs chemical routes targeting their inactivation in order to overcome the current limitations of the therapeutic use of MMPs inhibitors, i.e., easy clinical application and long-lasting effect.…”
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Walters B’ hybrid nanofluid flow with Marangoni convection by Rupa Baithalu, Subhajit Panda, S.R. Mishra

“…The standard conservation equations are transmuted into an ordinary set of equations implementing similarity functions and then a numerical approach is implemented for the solution. …”
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Identification of Hotspot Regions for Candidate Genes Associated with Peanut (<i>Arachis hypogaea</i> L.) Pod and Seed Size on Chromosome A05 by Xiaoji Zhang, Luhuan Wang, Qimei Liu, Xiaoyu Zhang, Yuexia Tian, Yunyun Xue, Huiqi Zhang, Na Li, Xin Zhang, Dongmei Bai

“…In this study, we employed advanced generation recombinant inbred lines developed by crossbreeding Huayu 44 and DF12 as the experimental material. Quantitative trait locus (QTL) mapping for traits related to pod and seed size was conducted across six environments. …”
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Aptamer/Dopamine Molecularly Imprinted Polymer Composite Based pH Stability Improved Electrochemical Sensor for Simultaneous Detection of Cd(Ⅱ) and Hg(Ⅱ) by Xinyu Fang, Xinna Liu, Jiahao Sha, Nianxin Zhu, Yihang Yang, Tai Ye, Hui Cao, Min Yuan, Liling Hao, Fei Xu

“…Dopamine was used as a functional monomer for self‐polymerization to form an imprinted layer, stabilizing the aptamer conformation and enhancing its environmental tolerance. …”
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MODERN ASPECTS OF TREATMENT OF ESOPHAGEAL CANCER by U. B. Urmonov, A. Yu. Dobrodeev, S. G. Afanasyev, A. V. Avgustinovich, O. V. Cheremisina

“…The choice of the treatment option for esophageal cancer remains a challenging clinical problem and depends on the particular type of cancer, tumor stage, functional status of patients.…”
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Quality control of blood components: selection of laboratory testing methods by E. N. Kalinina, N. S. Vildanova, E. S. Kormshchikova, E. A. Konovalova, N. V. Isaeva, T. V. Krivokorytova, M. E. Kovtunova, K. A. Vorobiev

“…One of the main tasks of blood service institutions is the procurement of high-quality transfusion media, the effectiveness of which directly depends on the functioning of the safety system. The implementation of this direction of work is impossible without laboratory testing of the donor biomaterial, a prerequisite for which is the standardization of procedures to ensure the reliability and reproducibility of the results. …”
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