Results of a 12-week open-label, non-interventional study of the efficacy and safety of olokizumab therapy in patients with rheumatoid arthritis after switching from anti-B-cell th... by A. A. Akimova, N. E. Banshchikova, A. E. Sizikov, A. A. Mullagaliev, E. A. Letyagina, N. A. Ilina, Yu. D. Kurochkina, Yu. B. Ubshaeva, V. O. Omelchenko, O. A. Chumasova, N. S. Shkaruba, M. A. Korolev

“…All patients showed a reduction in pain (VAS scale) by week 8. The functional status of patients, according to the HAQ index, showed a significant decrease only by the 12th week of the study: Me baseline = 1.62, Me 12 weeks = 1.31 (p<0.05).Conclusion. …”
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Charcteristics of the Autonomic Nervous System in Patients with Liver Cirrhosis and its Dependence on the Severity of Portal Hypertension due to the Values of the Heart Rate Variab... by Abrahamovych M., Ferko M.

“…Wein, exploring the autonomic nervous system, primarily it is important to assess its functional status according to the results of functional and dynamic studies: tone, autonomic reactivity and vegetative support of the body, the first two of which characterize the homeostatic capabilities of the organism, and the last – adaptive. …”
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Biological protection of plants in agricultular landscape—state of the art, problems and ways of their decision by Sokolov M S, Kolombet L V

“…</list-item> </list>Thus, artificial agrocenoses and agroecosystems are immanent components of the agrospehere. Functioning of their bioresources meets the same laws of the Nature, as the functioning of the biota of natural ground ecosystems. …”
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PECTIN THERAPY IS A METHOD OF PREVENTION OF REPRODUCTIVE LOSSES ASSOCIATED WITH INTRAPLACENTARY ACCUMULATION OF RADIONUCLIDES by А. Живецька- Денисова, І. Воробйова, Н. Скрипченко, Л. Лозова, О. Шамаєва, Н. Рудакова, С. Стрижак

“…The accumulation of 137Cs in the placenta disrupts its architecture, functionality, and peroxide hemostasis. Detox defects due to 137Cs require correction to prevent reproductive losses. …”
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¿Los pacientes octogenarios sometidos a reemplazo total de rodilla regresan a la actividad física? by J. Teves, F. Holc, A. García-Mansilla, S. Vildoza, R. Brandariz, L. Carbó, J. Costantini

“…Abstract: Background and objectives: It has been shown that total knee replacement improves functional capacity and physical activity; however, the influence of age remains unclear. …”
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Integrated Genome-Wide Analysis of Gene Expression and DNA Copy Number Variations Highlights Stem Cell-Related Pathways in Small Cell Esophageal Carcinoma by Di Liu, Xinyan Xu, Junmiao Wen, Liyi Xie, Junhua Zhang, Yuxin Shen, Guoliang Jiang, Jiayan Chen, Min Fan

“…Gene enrichments in addition to functional annotation and gene interaction networks were performed using DAVID 6.8 and STRING 10.0, respectively. …”
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[Translated article] Do octogenarian patients undergoing total knee replacement return to physical activity? by J. Teves, F. Holc, A. García-Mansilla, S. Vildoza, R. Brandariz, L. Carbó, J. Costantini

“…Background and objectives: It has been shown that total knee replacement improves functional capacity and physical activity; however, the influence of age remains unclear. …”
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Effectiveness of postsurgical rehabilitation following lumbar disc herniation surgery: A systematic review by Hainan Yu, Carol Cancelliere, Silvano Mior, Paulo Pereira, Margareta Nordin, Ginny Brunton, Jessica J. Wong, Heather M. Shearer, Gaelan Connell, Lauren Ead, Leslie Verville, Mana Rezai, Danny Myrtos, Dan Wang, Andrée-Anne Marchand, Andrew Romanelli, Darrin Germann, Daphne To, James J. Young, Danielle Southerst, Henry Candelaria, Sheilah Hogg-Johnson, Pierre Côté

“…Research question: To investigate the effectiveness and safety of rehabilitation interventions initiated within three months post-surgery for adults treated surgically for LDH. Material and methods: This systematic review searched seven databases from inception to November 2023. …”
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Physiological and Gene Expression Responses of Crassostrea ariakensis to Salinity Stress by Miaomiao YANG, Sudong XIA, Zhihong LIU, Xiujun SUN, Liqing ZHOU, Peizhen MA, Zhuanzhuan LI, Biao WU

“…Oysters are keystone species in marine ecosystems and essential for restoring ecological function and maintaining biodiversity maintenance. …”
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Research on Stacking Distribution of Steel Plates Input Based on Improved Multi-objective Particle Swarm Optimization by ZHONG Chuanjie, CHENG Wenming, DU Run, GAO Xuchao, ZHANG Lin

“…The inventory balance index was established based on the standard deviation of the number of steel plates allocated to each reservoir to fully mobilize and balance material storage resources during operation. These three indices were utilized to evaluate the degree of stack allocation and served as the objective function to establish a multi-objective decision optimization model for the stack allocation problem of steel plates. …”
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„Solvumiseks pole põhjust.“ Vaimne õhustik Eesti NSV Heliloojate Liidu töökoosolekutel 1970. aastatel / “No Reason to Be Offended”: The Atmosphere at Working Meetings of the Eston... by Anu Veenre

“…By the 1970s, although the meetings’ ideological function remained in place, changes in the political climate and the rise of a new generation of composers had altered both the meetings’ atmosphere of control and the rhetoric of discussion. …”
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Structural Parameter Identification Using Multi-Objective Modified Directional Bat Algorithm by LIU Li-jun, LIN Ying-hai, SU Yong-hui, LEI Ying

“…Fourteen structural parameters， such as elastic modulus， material density， and sectional properties， were optimized. …”
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Development of a core patient-centred outcome set for adults living with obesity: a modified delphi-based international consensusResearch in context by Teferi Mekonnen, Leanne Staniford, Spencer Connell, Zofia Das-Gupta, Umanga DeSilva, Yasmine Saoud, Isabel Miller, Mohapradeep Mohan, Simon Nienhuijs, Megha Poddar, Vaishali Chetan Deshmukh, Marli Conradie-Smit, Soo Huat Teoh, Sanjeev Sockalingam, Emilia Huvinen, Paolo Sbraccia, Ronald Liem, Michael Vallis, Kenneth Clare, Tracy Zvenyach, Karen Coulman, Marianela Aguirre Ackermann, Verónica Vázquez-Velázquez, Yudith Preiss Contreras, Josep Vidal, Agbo Urudinachi, María Fernanda Tejeda-Muñoz, Ian Patton, T Alafia Samuels, Morgan Emile Gabriel Salmon Leguede, Georgia Rigas, Ximena Ramos Salas, Michael Crotty, Bruno Halpern, Daniel Bessesen, Laura Pizzi, Omniyat Mohammed Al Hajeri, Arya M. Sharma

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Panel containing three serum microRNAs: a promising biomarker for early detection of bladder cancer by Zhenjian Ge, Zhenjian Ge, Zhenjian Ge, Zhenjian Ge, Shengjie Lin, Shengjie Lin, Shengjie Lin, Shengjie Lin, Chong Lu, Chong Lu, Chong Lu, Chong Lu, Yong Xia, Rongkang Li, Rongkang Li, Rongkang Li, Rongkang Li, Xinji Li, Xinji Li, Xinji Li, Xinji Li, Chen Sun, Chen Sun, Chen Sun, Chen Sun, Zhenyu Wen, Zhenyu Wen, Zhenyu Wen, Zhenyu Wen, Wenkang Chen, Wenkang Chen, Wenkang Chen, Wenkang Chen, Yingqi Li, Yingqi Li, Yingqi Li, Yingqi Li, Mingyang Li, Yu Lin, Jing Dong, Lingzhi Tao, Lingzhi Tao, Lingzhi Tao, Ling Ji, Yongqing Lai, Yongqing Lai, Yongqing Lai

“…Additionally, we used bioinformatic analysis to explore the potential biological functions of the crucial miRNAs.ResultsThe diagnostic panel consisted of miR-212-3p, miR-30c-5p, and miR-206, with an area under the curve (AUC) of 0.838, sensitivity of 83.33%, and specificity of 73.81%. …”
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The Analysis of the Effective Factors on Urban Blight in District 3, Region 12, Tehran City by Hossein Mansourian, Ahmad Pour Ahmad, Hasan Ashouri

“…In accordance with population growth and physical extension, the central part of Tehran has experienced many changes including the movements of original inhabitants and resettled immigrants, changes in the combination and variety of urban land use making them the backup land uses of some of the original ones, coincidence of functional fatigue and physical fatigue, the increase of crime and social harms, and the decrease of the level of public services required by inhabitants. …”
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Spectrum of Cortactin Isoforms in the Urine of Patients with Liver Cirrhosis and Their Diagnostic Value as a Potential Molecular Marker of its Severity by Fayura O., Starikovych M., Abrahamovych O., Abrahamovych M., Stoyka R., Kit Yu.

“…Since the protein content of human urine is closely related to the peculiarity of the functioning of biological systems, its qualitative and quantitative characteristics are promising markers for control of various processes in organism. …”
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Optimized lipid nanoparticles enable effective CRISPR/Cas9-mediated gene editing in dendritic cells for enhanced immunotherapy by Kuirong Mao, Huizhu Tan, Xiuxiu Cong, Ji Liu, Yanbao Xin, Jialiang Wang, Meng Guan, Jiaxuan Li, Ge Zhu, Xiandi Meng, Guojiao Lin, Haorui Wang, Jing Han, Ming Wang, Yong-Guang Yang, Tianmeng Sun

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火麻蛋白肽体内降血压功效研究Hypotensive effect in vivo of hemp protein peptides by 卫萍1,2，刘国明2,3，韦珍1，邓中霖1 WEI Ping1,2, LIU Guoming2,3, WEI Zhen1, DENG Zhonglin1

“…In order to provide a theoretical basis for the use of hemp seed protein as a functional factor for lowering blood pressure, hemp seed protein was prepared by the alkali-soluble and acid-precipitation method with hemp kernel as materials, hemp protein peptides were prepared through a stepwise enzymatic hydrolysis process, and then hemp protein peptides were used as raw material to explore its hypotensive effect in vivo in terms of animal experiments. …”
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Regulation of land use conflicts at indigenous peoples lands based on blockchain platform, russian arctic case study by A. V. Evseev, T. M. Krasovskaya, V. S. Tikunov, I. N. Tikunova

“…The goal of this investigation is the elaboration of a multi-functional information platform based on blockchain principles needed to achieve adaptive development of TTNU involved in the process of land use patterns transformation. …”
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Unveiling the third dimension of glass by Faidra Oikonomopoulou

“…At present, the load-bearing function of cast glass in architecture remains an uncharted field. …”
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