Jianwei Xiaoshi oral liquid attenuates high-calorie diet-induced dyspepsia in immature rats via regulating the pancreatic secretion pathway and maintaining the homeostasis of intes... by Yan Zhang, Xiaolu Wei, Shan Jiang, Wenya Gao, Kun Wang, Hongjie Wang, Huijun Wang, Nan Si, Yanyan Zhou, Keke Luo, Mengxiao Wang, Yuyang Liu, Lihua Chen, Liqi Ni, Haiyu Zhao

“…It originates from Jianpi Pill, which is developed in the Ming Dynasty and nourishes the spleen and regulates gastrointestinal function. However, the specific molecular mechanisms involved remain unclear. …”
Get full text

Heart transplantation as a radical method of restoring the quality of life in recipients with end-stage heart failure by S. V. Gautier, V. M. Zacharevich, T. A. Khalilulin, A. О. Shevchenko, V. N. Poptsov, R. L. Ahmadzai, A. M. Goltz, A. R. Zakiryanov, N. N. Koloskova, N. Y. Zacharevich, E. А. Nikitina, O. A. Pozdnyakov, K. S. Kiryakov

“…The most complete indicators of quality of life are restored after one year of operation: physical functioning (p = 0.00007), role-based functioning due to physical condition (p = 0.00006), pain threshold (p = 0.04), general health (p = 0.00007), mental health (p = 0.0001), role functioning due to the emotional state (p = 0.01), social functioning (p = 0.0001), vital activity (p = 0.000032). …”
Get full text

Research Progress on Fermentation Microorganisms and Flavor Compounds in Pixian Broad Bean Paste by Wen YANG, Jiayue XU, Peishu YANG, Yungui LAN, Sijia PENG, Yang ZHAO, Binyuan ZHAO, Dong YANG, Liang ZHAO, Xiaojun LIAO

“…Moreover, recent studies have discovered the presence of antioxidant and antihypertensive peptides in PBBP, which have significant implications for the development of functional foods and the assessment of health values. …”
Get full text

Novel photodynamic therapy using two-dimensional NiPS3 nanosheets that target hypoxic microenvironments for precise cancer treatment by Wu Zongze, Liu Quan, Wageh Swelm, Sun Zhe, Al-Hartomy Omar A., Al-Sehemi Abdullah G., Yan Lesen, Chen Jiaojuan, Zhang Wenjian, Yang Jilin, Zhang Han, Liu Liping

Get full text

Expert consensus on the technical specifications of the in vitro skin penetration test of cosmetic product by Franz diffusion cell by Bingwen Liang, Liling Zhou, Chuanbin Wu, Liang Fang, Lisheng Wang, Lihua Peng, Peng Shu, Lifeng Tang, Yu Bei, Xiaodong Cui, Xiaojia Chen, Yuan Gao, Chong Han, Yan Jia, Huaqing Lin, Yifang Li, Ying Liu, Yiguang Li, Zhiwei Li, Zixiu Liu, Shaohua Ren, Jun Shi, Wanyang Sun, Lijuan Tian, Qun Wang, Yuan Wang, Yuehong Xu, Ming Zeng, Quangang Zhu, Shu Zhang, Yifan Zhang, Qi Xiang

“…Objective: In order to improve the standardized level and make the in vitro percutaneous absorption test of cosmetic ingredients more comparable, based on the international and domestic experience, Transdermal Drug Delivery Committee of the World Federation of Chinese Medicine Societies organized the experts to discuss and formed this consensus as reference for the percutaneous absorption test of cosmetic components. Materials and Methods: To standardize the in vitro diffusion cell test technique for transdermal penetration of functional cosmetic ingredients, the Transdermal Drug Delivery Professional Committee of the World Federation of Societies of Traditional Chinese Medicine has organized many discussions among experts. …”
Get full text

Phycobilins Versatile Pigments with Wide-Ranging Applications: Exploring Their Uses, Biological Activities, Extraction Methods and Future Perspectives by Celestino García-Gómez, Diana E. Aguirre-Cavazos, Abelardo Chávez-Montes, Juan M. Ballesteros-Torres, Alonso A. Orozco-Flores, Raúl Reyna-Martínez, Ángel D. Torres-Hernández, Georgia M. González-Meza, Sandra L. Castillo-Hernández, Marcela A. Gloria-Garza, Miroslava Kačániová, Maciej Ireneusz-Kluz, Joel H. Elizondo-Luevano

“…The future perspectives for PBs focus on their incorporation into innovative drug delivery systems, biocompatible materials, and functional foods, presenting exciting opportunities for advancing human health and well-being.…”
Get full text

Climate Change and Outdoor Workers: A Narrative Review by Mehdi Asghari, Mohammad Javad Ghanadzadeh, Razieh Soltani Gerdfaramarzi

“…Heat strain, volume depletion and kidney function in California agricultural workers. Occupational and environmental medicine. 2017;74(6):402-9. …”
Get full text

Simultaneously acquired rSUV and rCBF of 18F-FDG/MRI in peritumoral brain zone can help to differentiate the grade of gliomas by Hong Qu, Yuping Zeng, Lifeng Hang, Jin Fang, Hui Sun, Hong Li, Guihua Jiang

Get full text

Changes in microbiome composition after fecal microbiota transplantation via oral gavage and magnetic navigation technology-assisted proximal colon/cecum enema in antibiotic knock-... by Xian-Jie Bai, Yu-Chen Mei, Jia-Tong Zhao, Zhi-Ren Chen, Chen-Xi Yang, Xiao-Juan Dong, Jia-Wei Yu, Lin-Biao Xiang, Er-Zheng Zhou, Yong Chen, Jia-Yi Hao, Zhi-Jie Zhang, Yu-Xuan Liuyang, Lu Ren, Ying-Min Yao, Lei Zhang, Yi Lv, Qiang Lu

“…Besides, the difference in fecal microbiota composition after FMT via oral gavage and proximal colon/cecum enemas was determined in antibiotic knock-down rats, in addition to the impact on intestinal barrier function. Methods A device consisting of an external magnet and a magnet-tipped 6 Fr tube was used in the MAT group (n = 6), and the control group (n = 6) where fecal matter was delivered without magnetic navigation. …”
Get full text

Indian Subcontinent’s First Bilateral Supracondylar Level Upper Limb Transplantation by Mohit Sharma, Subramania Iyer, Kishore P., Jimmy Mathew, Janarthanan R., Nirav Maharaja, Swapnil Dhake, Akshay Omkumar, Thomas Joe, Dimpy Sharma, Radhika Kapathia, Ankita Harijee, Srilekha Reddy, Jerry Paul, Sunil Rajan, George Kurian, Zacharia Paul, Druvan Shaji, Balu C. Babu, Anubhav Sharma

“…This article describes only the technical considerations. The functional recovery aspect is part of an another soon to be published manuscript. …”
Get full text

Integrated analysis of transcriptome and proteome provides novel insights into the response mechanisms of maca (Lepidium meyenii Walp.) to UV-B radiation by Zaihang Yu, Xueting Zhong, Li Xiao, Yuxi Cai, Ke Shen, Yu Luo, Xinxin Li, Hong Xu, Zihan Chen, Xiaomei Wang, Yi Wu, Yajun Wang, Wei Fan, Zhanqi Wang

Get full text

Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium by Jonathan R. Soucy, Erika A. Aguzzi, Julie Cho, Michael James Gilhooley, Casey Keuthan, Ziming Luo, Aboozar Monavarfeshani, Meher A. Saleem, Xue-Wei Wang, Juilette Wohlschlegel, The RReSTORe Consortium, Petr Baranov, Adriana Di Polo, Brad Fortune, Kimberly K. Gokoffski, Jeffrey L. Goldberg, William Guido, Alex L. Kolodkin, Carol A. Mason, Yvonne Ou, Thomas A. Reh, Ahmara G. Ross, Brian C. Samuels, Derek Welsbie, Donald J. Zack, Thomas V. Johnson

“…RGC repopulation is a promising therapeutic approach to reverse vision loss from optic neuropathies if the newly introduced neurons can reestablish functional retinal and thalamic circuits. In theory, RGCs might be repopulated through the transplantation of stem cell-derived neurons or via the induction of endogenous transdifferentiation. …”
Get full text

Phyto-fabrication of copper oxide nanoparticles (NPs) utilizing the green approach exhibits antioxidant, antimicrobial, and antifungal activity in Diospyros kaki fruit by Iftikhar Hussain Shah, Irfan Ali Sabir, Muhammad Ashraf, Asad Rehman, Zishan Ahmad, Muhammad Azam, Ghulam Abbas Ashraf, Haroon ur Rasheed, Guohui Li, Jeridi Mouna, Mohammad Faizan, Muhammad Ahsan Altaf, Awais Shakoor, Cheng Song, Muhammad Aamir Manzoor

“…The FTIR analysis revealed the functional groups present in plant extracts. XRD was carried out to demonstrate the crystalline nature and size of nanoparticles using the Scherrer formula. …”
Get full text

Comparative study of the clinical efficacy of the first domestic bioanalogue of tocilizumab based on the results of a randomized clinical trial of phase III by E. V. Akatova, Yu. S. Bakhareva, O. V. Bugrova, I. B. Vinogradova, E. V. Gerasimova, Yu. E. Drevina, O. B. Ershova, E. V. Zonova, Yu. I. Ivanova, E. P. Ilivanova, M. M. Kostik, D. G. Krechikova, D. A. Kusevich, A. L. Maslyansky, A. D. Meshkov, N. S. Mosesova, K. A. Nagornova, D. V. Nosovich, S. A. Polyakova, T. A. Popova, E. A. Smolyarchuk, V. N. Sorotskaya, Yu. G. Shvarts, L. N. Shilova, M. S. Shostak, I. Yu. Yunonin, N. E. Akhtyamova-Givirovskaya, R. A. Khamitov, O. A. Markova, E. I. Zagoruiko, E. V. Zuev

“…Comparability of the biosimilar CPR and the reference drug ACT is also confirmed by the results of secondary efficacy endpoints: the proportion of patients with ACR50/70, dynamics of the DAS28, SDAI, CDAI, the functional activity of patients (HAQ), laboratory parameters of inflammatory activity (ESR and CRP). …”
Get full text

The outcomes of salvage robotic radical prostatectomy following radiation versus focal therapy: Does the primary treatment modality matter? by Alireza Ghoreifi, Lorenzo Storino Ramacciotti, Masatomo Kaneko, Luis G. Medina, Giovanni E. Cacciamani, Shiran Konganige, Manju Aron, Sarmad Sadeghi, Hossein Jadvar, Hooman Djaladat, Rene Sotelo, Mihir M. Desai, Inderbir S. Gill, Monish Aron, Andre Luis Abreu

“…Perioperative findings and functional/oncologic outcomes were compared in RT versus FT groups. …”
Get full text

Percutaneous implantation of self-expanding pulmonary valves: results from real-life experience of the Venus-P valve Registry of the Italian Society of Pediatric Cardiology (SICPED... by M. Pilati, F.A. D'Aiello, M. Chessa, G. Santoro, A. Donti, E. Mariucci, C. Marrone, G. Annoni, G. Gaio, M. Rebonato, E. Piccinelli, M. Cheli, R. Formigari, G. Butera

“…During follow up (median 13 months,1–20months), all patients experienced a significant improvement of functional class. Neither deaths or re-intervention occurred. …”
Get full text

Impact of the Use of 2-Phospho-L Ascorbic Acid in the Production of Engineered Stromal Tissue for Regenerative Medicine by David Brownell, Laurence Carignan, Reza Alavi, Christophe Caneparo, Maxime Labroy, Todd Galbraith, Stéphane Chabaud, François Berthod, Laure Gibot, François Bordeleau, Stéphane Bolduc

“…This study aims to demonstrate the functional equivalence of 2-phospho-L-ascorbate (2PAA), a stable form of AA, for tissue reconstruction. …”
Get full text

Markers of vascular damage depending on the blood pressure level: data of the population study ESSE-RF by A. M. Erina, M. A. Boyarinova, E. V. Moguchaya, E. P. Kolesova, A. S. Aliyeva, O. P. Rotar, E. I. Baranova, S. A. Shalnova, A. D. Deev, Z. T. Astakhova, L. Z. Bolieva, G. V. Tolparov, V. S. Kaveshnikov, V. N. Serebryakova, I. A. Trubacheva, R. S. Karpov, A. Yu. Efanov, M. A. Storozhok, I. V. Medvedeva, S. V. Shalaev, A. N. Rogoza, A. O. Konradi, S. A. Boytsov, E. V. Shlyakhto

“…To evaluate the relationship of prehypertension (preHTN) with vascular wall damage and decreased renal function depending on cardiovascular risk in a representative sample of Russian population.Material and methods. …”
Get full text

Algorithm of reconstruction combined midface defects after resection malignant tumors by M. V. Bolotin, A. M. Mudunov, V. Yu. Sobolevsky, V. I. Sokorutov

“…Till that time, no algorithm has been developed for choosing a method for the reconstruction and there is no comparative analysis of the available methods.The study objective is to improve the functional and aesthetic results of treatment patients with malignant tumors of the upper jaw and midface.Materials and methods. …”
Get full text

Features of Lipid Spectrum and Insulin Resistance Parameters in Patients with Type 2 Diabetes Mellitus and Cardiac Autonomic Neuropathy and Appropriateness of Simvastatin and Omega... by Azhmi S., Serhiyenko V.

“…The aim of this study was to investigate the blood lipid profile and IR parameters in patients with T2DM and CAN and the effects of simvastatin and ω-3 PUFAs prescription. Materials and methods. The study involved 219 patients with T2DM (101 women and 118 men, patients were aged between 50-59 years), among them: 1) 19 patients without CAN; 2) 44 – with subclinical CAN; 3) 156 (aged 50-59 years, disease duration 1-6 years, glycated haemoglobin A1c (HbA1c) level (7,1 ± 0,4) %) – with functional CAN. …”
Get full text