Evolution of Untreated Moderate Mitral Regurgitation After Transcatheter Aortic Valve Implantation by Massimo Baudo, Serge Sicouri, Francesco Cabrucci, Yoshiyuki Yamashita, Dimitrios E. Magouliotis, Sarah M. Carnila, Sandra V. Abramson, Katie M. Hawthorne, Harish Jarrett, Roberto Rodriguez, Scott M. Goldman, Paul M. Coady, Eric M. Gnall, William A. Gray, Sandro Gelsomino, Basel Ramlawi

“…<i>Results</i>: Mean age was 81.4 ± 7.8 years, 48.1% (74/154) were female, and 48.1% (74/154) were functional MR. There was one surgical conversion due to annular rupture. …”
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Inhibition of carbohydrate digestive enzymes by a complementary essential oil blend: in silico and mixture design approaches by El Hassania Loukili, Mouhcine Fadil, Amal Elrherabi, Mohammed Er-rajy, Mohamed Taibi, Khalil Azzaoui, Khalil Azzaoui, Rachid Salghi, Rachid Sabbahi, Mohammed M. Alanazi, Larbi Rhazi, Aleksandar Széchenyi, Aleksandar Széchenyi, Mohamed Siaj, Belkheir Hammouti

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Clinical and Ultrasound Evaluation of Hemiplegic Shoulder Pain in Stroke Patients: A Longitudinal Observational Study Starting in the First Hours After Stroke by Filippo Cotellessa, William Campanella, Luca Puce, Maria Cesarina May, Marta Ponzano, Riccardo Picasso, Matteo Mordeglia, Davide Subbrero, Ester Cecchella, Laura Mori, Davide Sassos, Massimo Del Sette, Matteo Formica, Carlo Trompetto

“…Evaluations included pain severity during passive shoulder mobilization, passive and active range of motion, muscle strength, spasticity, and functional disability. Ultrasound examinations were conducted to assess tendon disorders, bursitis, effusion, glenohumeral subluxation, and adhesive capsulitis. …”
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Fluorescence Quenching of Graphene Quantum Dots from Orange Peel for Methyl Orange Detection by Weitao Li, Yang Liu, Xinglong Pang, Yuanhao Huang, Zeyun Dong, Qian Niu, Yuping Xiong, Shang Li, Shuai Li, Lei Wang, Huazhang Guo, Saisai Cui, Shenpeng Hu, Yuenan Li, Tiantian Cha, Liang Wang

“…Additionally, the GQDs possess high specific surface area, abundant surface functional groups, and excellent electronic conductivity, which contribute to their effective fluorescence quenching performance. …”
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Prevalence of hepatitis B virus infection and associated factors among students living on campus in South-eastern Gabon by Augustin Mouinga-Ondeme, Moussa Yaro, Guy-Roger Ndong Atome, Madeleine Meba, Neil Michel Longo-Pendy, Roseanne Mounanga Mourimarodi, Christ Eddy Ognari Ayoumi, Abdoulaye Diane, Jeordy Dimitri Engone-Ondo, Eldridge Fedricksen Oloumbou, Ivan S. Mfouo Tynga

“…Abstract Background The Hepatitis B-virus is the etiological agent of an infection that affects liver functions and potentially causes disorders. Approximately, 300 million people are living with acute or chronic HBV-infections worldwide, and only a fraction of them have access to medical care. …”
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Anatomical Variants in Pancreatic Irrigation and Their Clinical Considerations for the Pancreatic Approach and Surrounding Structures: A Systematic Review with Meta-Analysis by Juan José Valenzuela-Fuenzalida, Camila Ignacia Núñez-Castro, Valeria Belén Morán-Durán, Pablo Nova-Baeza, Mathias Orellana-Donoso, Alejandra Suazo-Santibáñez, Alvaro Becerra-Farfan, Gustavo Oyanedel-Amaro, Alejandro Bruna-Mejias, Guinevere Granite, Daniel Casanova-Martinez, Juan Sanchis-Gimeno

“…This blood supply is structured into three main arterial groups, each serving different regions of the pancreas to effectively support its endocrine and exocrine functions. <i>Materials and Methods</i>: The databases Medline, Scopus, Web of Science, Google Scholar, Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Latin American and the Caribbean Literature in Health Sciences (LILACS) were searched until January 2025. …”
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Environmentally Friendly Synthesis of New Mono- and Bis-Pyrazole Derivatives; In Vitro Antimicrobial, Antifungal, and Antioxidant Activity; and In Silico Studies: DFT, ADMETox, and... by Oussama Merzouki, Nadia Arrousse, Elhachmia Ech-chihbi, Ashwag S. Alanazi, El Houssine Mabrouk, Mohamed Hefnawy, Abdelfattah El Moussaoui, Hanane Touijer, Azeddin El Barnossi, Mustapha Taleb

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MicroRNA-32-5p inhibits metastasis by directly targeting VPS4B and increases sensitivity to dihydroartemisinin in neuroblastoma by Lina Chen, Hui Liu, Zhongyuan Zheng, Shuiqing Qu, Yu Zhang, Shuoqiu Deng, Shuo Shen, Tuo Liu, Yue Dai, Yu Li, Honghua Cui, Yujie Li

“…The primary objective of the current investigation was to characterize a newly discovered microRNA, miR-32-5p, in terms of the functional role, underlying mechanism of action, and potential synergistic therapeutic impact in the context of NB metastasis. …”
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Comorbidity Burden in Chronic Thromboembolic Pulmonary Hypertension: Implications and Outcome by Burcak Kilickiran Avci, Ibrahim Basarici, Mehmet Akbulut, Halil Atas, Yalin Tolga Yaylali, Umit Yasar Sinan, Ersan Atahan, Murat Meric, Baris Kaya, Kardelen Ohtaroglu Tokdil, Ozden Calay, Hasan Tokdil, Bulent Mutlu, Mehmet Serdar Kucukoglu, Zeki Ongen

“…<i>Conclusions</i>: A high comorbidity burden is common in CTEPH and influences functional status, hemodynamics, and operability decisions. …”
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Short-term use of ceftriaxone sodium leads to intestinal barrier disruption and ultrastructural changes of kidney in SD rats by Wenli Zou, Yueming Liu, Wei Zhang, Bo Lin, Wei Shen, Yiwen Li, Qiang He, Juan Jin

“…In addition, KEGG metabolic prediction revealed different metabolic functions in each group. TEM examination of colon revealed that dramatic morphological changes were observed in the ceftriaxone (Cef) group, wherein microvilli were misaligned and shortened significantly and morphologically intact bacteria were seen on the epithelial cell surface. …”
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Why do patients with isolated PCL rupture experience no subjective knee joint instability during walking? An in vivo biomechanical study by Mingfeng Lu, Mingfeng Lu, Wei Chen, Jinpeng Lin, Jinpeng Lin, Wenhan Huang, Junqing Gao, Junqing Gao, Lilian Zhao, Shilin Li, Lilei He, Yu Zhang

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Dose-dependent effects of capsaicin on intestinal morphology and microbiota composition in mice: Structural, immunohistochemical, and microbial insights by Kai Li, Jianghai Xu, Siying Chen, Aifei Du, Shaohua Feng, Shibin Yuan, Bangyuan Wu

“…While low-dose administration supports mucosal integrity and promotes beneficial microbial functions, higher doses disrupt epithelial architecture and induce dysbiosis. …”
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A novel Tc17 population recruited by tumor cells promotes tumor progression in gastric cancer by Yichao Wang, Yichao Wang, Hao Yuan, Yayun Tan, Li Wu, Li Wu, Xinchen Zhao, Xinchen Zhao, Zeyuan Yang, Zeyuan Yang, Shaoxing Dai, Shaoxing Dai, Naixue Yang, Naixue Yang

“…However, the role of Tc17 cells are unclear.Materials and methodWe collected 296,879 cells from the single-cell sequencing data of 65 GC samples, along with spatial transcriptomic data from 10 GC samples, to further explore the role of Tc17 cells. …”
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Investigation of the «Structure – analgesic activity» Relationship Using Molecular Docking for Cyclooxygenases 1 and 2 in the Series 5-<i>N</i>-arylaminocarbonyl-6-(get)aryl-4-meth... by N. A. Buzmakova, K. V. Аndryukov, T. M. Zamaraeva, I. P. Rudakova, K. V. Podchezertseva, A. S. Goman, E. V. Avdeeva, N. V. Slepova, N. V. Dozmorova

“…To identify the dependence "structure – analgesic activity" using the method of molecular docking for cyclooxygenase type 1 and type 2 in the series of 5-N-arylaminocarbonyl-6-(get)aryl-4-methyl-1,2,3,6-tetrahydropyrimidine-2-thions.Materials and methods. 19 compounds 5-N-arylaminocarbonyl-6-(get)aryl-4-methyl-1,2,3,6-tetrahydropyrimidine-2-thions are objects of research The study of the interaction of tetrahydropyridine derivatives with COX 1 and 2 was carried out by the method of molecular docking by the AutoDock 4 program using scoring functions.Results and discussion. …”
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The Neurobehavioral Impact of Zinc Chloride Exposure in Zebrafish: Evaluating Cognitive Deficits and Probiotic Modulation by Madalina Ene, Alexandra Savuca, Alin-Stelian Ciobica, Roxana Jijie, Irina Luciana Gurzu, Luminita Diana Hritcu, Ionut-Alexandru Chelaru, Gabriel-Ionut Plavan, Mircea Nicusor Nicoara, Bogdan Gurzu

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Dip-coating of nylon/chitosan/hydroxyapatite/TiO2 biocoatings to improve durability of metallic prostheses by César A. García-Pérez, Carmina Menchaca-Campos, Jorge Arturo Sandoval-Espino, E. Eduardo Antunez, Alejandro Flores Nicolás, Mayra Alejandra Santillán-Urquiza, Jorge Uruchurtu

“…These findings highlight the potential of biocoating as an effective alternative for the protection and functionality of metallic implants, paving the way for further research focused on optimization and clinical application.…”
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Post-harvest processing methods have critical roles on the contents of active metabolites and pharmacological effects of Astragali Radix by Xiaoyan Zhang, Shengnan Jiang, Tingting Sun, Wenbing Zhi, Kairu Ding, Ziyao Qiao, Hong Zhang, Hong Zhang, Ye Li, Yang Liu, Yang Liu

“…BackgroundProcessing methods of traditional Chinese medicinal materials are critical in influencing the active metabolites and pharmacological effects. …”
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Study on Plant Morphological Traits and Production Characteristics of Super High-Yielding Soybean by Xue AO, Ming-hui ZHAO, Qian ZHU, Jie LI, Hui-jun ZHANG, Hai-ying WANG, Cui-mei YU, Chun-hong LI, Xing-dong YAO, Fu-ti XIE, Xiao-ri HAN

“…In summary, super high-yielding soybean cultivars have several main features: suitable plant height, high pod density, good leaf structure with strong functionality, and slow leaf senescence at the late reproductive stage, which is conducive to the accumulation of dry matter and improved yield.…”
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Issues of Interpretation and Application of the Notion of “International Legal Legitimation” by A. M. Korzhenyak

“…In the process of adapting to the changing realities of geopolitics and international law, collective legitimation has become one of the main political functions of the UN as a means of politically significant approval (or disapproval) of the behaviour and positions of states as consistent with international law and at the same time meeting the needs of the present, a means of recognising them as legitimate (or illegitimate). …”
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Left ventricular remodeling in normotensive Wistar rats exposed to intermittent hypoxia of different duration by Yu. M. Kolesnyk, M. Yu. Kolesnyk, O. V. Hancheva, M. I. Isachenko

“…Hypoxic effects are accompanied by structural and functional changes in the myocardium. There is a direct link between the duration of hypoxic exposures and the severity of left ventricular myocardial remodeling. …”
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