EXPRESSION FEATURES OF ANTIGENS INVOLVED IN THE FORMATION OF IMMUNOLOGICAL SYNAPSE IN CHRONIC LYMPHOCYTIC LEUKEMIA by D. S. Badmazhapova, I. V. Galtseva, E. Е. Zvonkov, Yu. O. Davydova, N. M. Kapranov, N. G. Chernova, N. G. Gabeeva, T. N. Moiseeva, A. M. Kovrigina, V. N. Dvirnyk, U. L. Dzhulakyan, E. N. Parovichnikova, V. G. Savchenko

“…Therefore, it became clear that the pathogenesis of CLL is not only escape of apoptosis but also the ability of CLL cells to cause T-lymphocyte anergy, thereby avoiding immune surveillance.Objective: to study the expression of FAS, co-stimulatory molecules CD80 and CD86, PD-1, PD-L1 on CLL cells, and also to study the basic subpopulations of T-cells (naїve, memory, effector cells).Materials and methods. The study included 46 CLL patients: 16 patients with disease progression after chemotherapy and 30 patients with newly diagnosed CLL. …”
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Dynamic optimization of a composite material robot arm using a flexible link and joint model by Marwah Ghazi Kareem, M. Abdularazza, Kawther K. Younus, Husam Jawad Abdulsamad, Luay S. Al-Ansari

“…The study aims to optimize the design of a six-degree-of-freedom robotic arm using advanced composite materials specifically carbon/polyester fiber-reinforced composites to achieve a lightweight yet stiff structure with superior dynamic performance. …”
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Integrative network pharmacology, transcriptomics, and proteomics reveal the material basis and mechanism of the Shen Qing Weichang Formula against gastric cancer by Yi Wang, Xiaoyu Sun, Mingming Ren, Fangqi Ma, Ruohan Zhao, Xiaohong Zhu, Yan Xu, Nida Cao, Yuanyuan Chen, Yongfu Pan, Aiguang Zhao

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Improved Anthropomorphic Robotic Hand for Architecture and Construction: Integrating Prestressed Mechanisms with Self-Healing Elastomers by Mijin Kim, Rubaya Yaesmin, Hyungtak Seo, Hwang Yi

“…Soft pneumatic robot-arm end-effectors can facilitate adaptive architectural fabrication and building construction. …”
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Prospects for combining the methods of haploid biotechnology and genome editing to improve spiked grains of the <i>Triticeae</i> family (review) by A. V. Zhiltsov, A. A. Chekalin, O. V. Popova, I. V. Duvanov, D. N. Miroshnichenko

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Caninoid Necro-Robots: Geometrically Selected Rearticulation of Canine Mandibles by Ben Jørgensen, Oscar Powell, Freddie Coen, Jack Lord, Yang Han Ng, Jeremiah Brennan, Gurå Therese Bergkvist, Parvez Alam

“…The already formed skeletal structures of deceased dogs (and other animals) are ideal natural material replacements for synthetic robotic architectures such as plastics, metals, and composites. …”
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3D-printed PCL scaffolds combined with injectable sodium alginate/magnesium-doped mesoporous bioactive glass nanosphere hydrogel for meniscus regeneration: In vitro, In vivo, and m... by Hao Li, Yongkang Yang, Tianze Gao, Runmeng Li, Chao Wang, Xue Wang, Tianyuan Zhao, Qinyu Tian, Zhixing Zhang, Ruiyang Zhang, Quanyi Guo, Zhiguo Yuan, Peifu Tang

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Pretreated exosomes by electrical stimulation accelerate bone regeneration by Jialu Chen, Jian Chen, Jiahao Chen, Renjie Lu, Ziyuan Liu, Yang Zhang, Chi Zhang

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Cyclooxygenase-2/prostaglandin E2 inhibition remodulated photodynamic therapy-associated immunosuppression for enhanced cancer immunotherapy by Tao Xu, Kehan Liu, Shuqi Mi, Yao Yao, Mengyao Zhang, Shujuan Xue, Feng Zhi, Sally-Ann Cryan, Dawei Ding

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The hexapeptide functionalized gold nanoparticles protect against sepsis-associated encephalopathy by forming specific protein corona and regulating macrophage activation by Zichen Song, Hongguang Chen, Wenfei Xu, Xiaoye Zong, Xiaoyu Wang, Yuting Ji, Jiameng Gong, Mimi Pang, Shan-Yu Fung, Hong Yang, Yonghao Yu

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Hyaluronic acid-anchored nanoparticles co-delivering emodin and siRNA confers protection against rheumatoid arthritis via macrophage polarization by Muting Qin, Penglu Chen, Huanxue Chen, Feng Liu, Wei He, Enyang Yao

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IL-15 functionalized biomimetic hybrid mRNA vaccine for enhanced NSCLC immunotherapy via synergistic activation of T cells and NK cells by Jueshuo Guo, Li Peng, Penglong Ma, Yaping Mai, Ting Gao, Na Yu, Wenbao Zuo, Jianhong Yang

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Microfriction Stir Welding of Aluminium Using ABB IRB 1410 Robot by R. Manoj Samson, R. Aravind, Solomon Jenoris Muthiya, Joshuva Arockia Dhanraj, Karthikeyan Velmurugan, Saw Lin Oo

“…Robot microfriction stir welding (RMFSW) process mainly relays on friction between the tool and material making it more suitable for joining metals in the industries such as automotive and aerospace applications. …”
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Accuracy Optimization of Robotic Machining Using Grey-Box Modeling and Simulation Planning Assistance by Minh Trinh, Michael Königs, Lukas Gründel, Marcel Beier, Oliver Petrovic, Christian Brecher

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VipD of Legionella pneumophila targets activated Rab5 and Rab22 to interfere with endosomal trafficking in macrophages. by Bonsu Ku, Kwang-Hoon Lee, Wei Sun Park, Chul-Su Yang, Jianning Ge, Seong-Gyu Lee, Sun-Shin Cha, Feng Shao, Won Do Heo, Jae U Jung, Byung-Ha Oh

“…These interactions prevent Rab5 and Rab22 from binding to downstream effectors Rabaptin-5, Rabenosyn-5 and EEA1, consequently blocking endosomal trafficking and subsequent lysosomal degradation of endocytic materials in macrophage cells. …”
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Study of the Immunobiological Properties of Surface Protein-Containing Antigens of <i>Streptococcus pneumoniae</i> Serotype 6B by O. M. Kukina, I. M. Gruber, N. K. Akhmatova, O. V. Zhigunova, E. A. Kurbatova, N. B. Egorova, N. E. Yastrebova

“…Investigation of the protective properties of surface protein-containing antigens isolated from the immunogenic strain S. pneumoniae 6B No. 296 and their influence on key effectors of innate immunity. Materials and methods. …”
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The peculiarities of eosinophil apoptosis damage in patients with severe therapy-resistant bronchial asthma by L. Yu. Nikitina, F. I. Petrovsky, I. I. Ivanchuk, A. E. Sazonov

“…Methods: clinical, functional, allergologic observation, the study of apoptosis effectors expression (Polymerase Chain Reaction). Material: 60 patients with severe BA. …”
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Иммуногистохимический и морфометрический анализ слизистой оболочки верхнечелюстной пазухи при выведении пломбировочных материалов в полость синуса...

“…In early terms (till 1 year) stay of root canal filling material in maxillary sinus in dominating processes in MM MS are an allergic inflammation with intensive infiltration of stroma by effectors cells, and epithelium reactions in a kind globet and bazalno-cellular hyperplasia. …”
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Mechanical Stretch Control of Adipocyte AKT Signaling and the Role of FAK and ROCK Mechanosensors by Tasneem Bouzid, Eunju Kim, Brandon D. Riehl, Ruiguo Yang, Viswanathan Saraswathi, Jason K. Kim, Jung Yul Lim

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Design, Fabrication, and Experimental Validation of Optical Microbots by Menaka Konara, Mishal Pokharel, Md Mainuddin Sagar, Yeongjin Kim, Kihan Park

“…Additionally, micro-sized end effectors allow them to make measurable physical contact with biological objects. …”
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