SURGICAL TREATMENT CHOICE FOR PATIENTS WITH NON-RESECTABLE PANCREATIC HEAD CANCER by Borys H. Bezrodnyi, Ihor V. Kolosovych, Yevhenii O. Nesteruk

“…With a Karnofsky index <80, it is advisable to perform stenting of the common bile duct with SEMS, with a Karnofsky index >80, double biliodigestive and prophylactic gastrodigestive bypass surgery should be performed. When multiorgan dysfunction and cholangitis develop against the obstructive jaundice, the treatment consists of two stages, the first – transpapillary biliary drainage with plastic stents, the second – elective surgical intervention.…”
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Assessment of association between the Pro12Ala polymorphism of PPAR-γ gene with the risk of obstetric complications by S. O. Ostafiichuk

“…Aim – to determine the association between Pro12Ala polymorphism of PPAR-γ gene with the risk of obstetric complications. Materials and methods. A total of 97 women with normal prepregnancy weight, singleton pregnancy, delivery at 37 weeks or more and without chronic diseases with follow-up of pregnancy and 1 year after delivery at antenatal clinics. …”
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Global longitudinal strain and its dynamics after replacement of aortal valve in patients with severe aortic stenosis by N.V. Ponych, O.O. Nemchyna, O.J. Zharinov, O.A. Yepanchintseva, B.M. Todurov

“…The aim – to determine factors that may influence the global longitudinal strain (GLS) and its dynamics after replacement aortic valve (RAV) in patients with severe aortic stenosis (AS). Materials and methods. In a one-center prospective study, 30 patients with severe AS were sequentially screened for RAV surgery. …”
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Mobile-phone-based e-diary derived patient reported outcomes: Association with clinical disease activity, psychological status and quality of life of patients with multiple scleros... by Daniel Golan, Smadar Sagiv, Lea Glass-Marmor, Ariel Miller

“…Secondary objectives were to evaluate the construct and predictive validity of e-diary derived PROs and to explore the various factors that were associated with changes in PROs over time.<h4>Materials and methods</h4>In this observational cohort study patients downloaded an MS tailored e-diary into their personal smartphones. …”
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Role of Sepsis in Obstetric Score (SOS) to identify severe sepsis in pregnant women requiring ICU admission: A prospective observational study by Sangeeta Shah, L Rani Kumari, Firdous Fatima, Sri Manju Challakolusu, Nishitha Tummala, Bathula Mounika

“…Introduction: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. …”
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Features of the cytokine profile in the structures of chorion and placenta in premature termination of pregnancy by A. A. Zhyvetska-Denysova, I. I. Vorobiova, N. Ya. Skrypchenko, V. B. Tkachenko

“…Structural and functional changes in the placenta against the background of inflammation make up the morphological substrate of chronic placental dysfunction, which, in a case of decompensation, triggers the process of preterm birth. …”
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Immunohistochemical study of the brain glutamine synthetase expression in the rat septic model by T. V. Shulyatnikova, V. O. Tumanskiy

“…Severe sepsis is accompanied by multiple organ dysfunction where acute liver failure (ALF) plays one of the most critical roles. …”
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The psychophysiological technology with biofeedback in complex rehabilitation of post-stroke patients: a randomized controlled study by Elena V. Kostenko, Anastasia V. Kotelnikova, Liudmila V. Petrova, Irena V. Pogonchenkova, Maksim S. Filippov

“…To evaluate the effectiveness of the MR-program including psychophysiological technology with BFB for patients with an ischemic stroke (IS). MATERIALS AND METHODS. The study includes patients in the early recovery period of IS with mild to moderate motor deficits, cognitive dysfunction and emotional-volitional disorders. …”
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Changes in coagulation parameters in polytrauma patients with different body mass index according to the enoxaparin-sodium dosing strategy under conventional versus restrictive flu... by М.О. Gogiya, S.V. Kursov, О.V. Markov, O.М. Kudrevych

“…Materials and Methods. A total of 201 patients with polytrauma and closed abdominal injury were enrolled and allocated to six groups. …”
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Practical experience and clinical results of reconstructive surgical correction of primary and secondary mitral regurgitation by V. V. Osaulenko, V. O. Hubka, K. O. Chmul, S. Yu. Nakonechnyi, R. I. Budahov

“…Mitral valve surgery is indicated in symptomatic patients with severe insufficiency and asymptomatic individuals with left ventricular systolic dysfunction, pulmonary hypertension, or atrial fibrillation. …”
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Prevalence of Sleep Apnea in Patients with Syncope of Unclear Cause: SINCOSAS Study by María-José Muñoz-Martínez, Alberto Fernández-Villar, Manuel Casal-Guisande, Enrique García-Campo, Dolores Corbacho-Abelaira, Ana Souto-Alonso, Bernardo Sopeña

“…<i>Background and Objectives:</i> The association between syncope and sleep apnea (SA) has been scarcely investigated. Dysfunction of the autonomic nervous system (ANS) may represent a shared pathophysiological mechanism. …”
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Relationship of cardiac and carotid arteries remodeling in women with arterial hypertension by I. M. Zubko

“…Significant and reliable negative relationship between media thickening, inner diameter of carotid arteries index and left ventricle EF has been established; it may indicate new peculiarities of the initial impact of vascular remodeling onLV systolic dysfunction development.…”
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Propolis mitigates histopathological alterations in the pituitary gland and reproductive system of female albino rats subjected to cadmium toxicity by Abdulla A. Albishtue, Aqeel Mohsin Al-Mahmmodi, Hasan A. Almamoori, Mustafa Ali Alahmer

“…These findings suggest PRO as a promising candidate for mitigating heavy metal-induced reproductive dysfunction.…”
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One-stage buccal two-flap urethroplasty using the Kulkarni technique for extended anterior urethral strictures by M. I. Katibov, M. M. Alibekov, Z. M. Magomedov, A. M. Abdulkhalimov, V. G. Aydamirov

“…The use of this technique for recurrent forms of the urethral stricture (recurrence after the previous urethroplasty) is the most significant risk factor for treatment failure. 1 (5.6%) case of erectile dysfunction and stress urinary incontinence has taken place of the late postoperative complications.Conclusions. …”
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The diagnostic value of brain natriuretic peptide in men with comorbid essential arterial hypertension and type 2 diabetes mellitus by Ya. O. Antoniuk, A. F. Humeniuk, Yu. P. Pashkova, O. O. Sakovych, V. M. Zhebel

“…The aim of the work is to investigate the diagnostic informativeness of brain natriuretic peptide (BNP) in men with left ventricular (LV) diastolic dysfunction (DD) and initial stages of chronic heart failure (CHF) in comorbid stage 2 essential hypertension (EH 2) and type 2 diabetes mellitus (T2DM). …”
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Shen-Qi-Jie-Yu-Fang exerts effects on a rat model of postpartum depression by regulating inflammatory cytokines and CD4+CD25+ regulatory T cells by Li J, Zhao R, Li X, Sun W, Qu M, Tang Q, Yang X, Zhang S

“…Aim: To further investigate the effect of SJF on the immune system, including the inflammatory response system and CD4+CD25+ regulatory T (Treg) cells. Materials and methods: Sprague Dawley rats were used to create an animal model of PPD by inducing hormone-simulated pregnancy followed by hormone withdrawal. …”
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Association between NOS3 gene rs1799983 polymorphism and the risk of developing preeclampsia as well as susceptibility to SARS-CoV-2 infection during pregnancy by R. I. Gabidullina, A. V. Ganeeva, P. L. Kapelyushnik, T. N. Shigabutdinova, E. V. Valeeva, A. F. Nurgatina

“…Preeclampsia (РЕ) is a complication of pregnancy resulting from a generalized vascular dysfunction. Systemic endotheliopathy also emerges due to a viral infection such as caused by SARS-CoV-2. …”
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The Impact of Age and Pathogens Type on the Gut Microbiota in Infants with Diarrhea in Dalian, China by Qingjie Fan, Ming Yi, He Liu, Yushuang Wang, Xinke Li, Jieli Yuan, Lili Wang, Binbin Hou, Ming Li

“…Diarrhea in infants is a serious gastrointestinal dysfunction characterized by vomiting and watery bowel movements. …”
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Early identification of autism spectrum disorder in preschoolers by static and dynamic amplitude of low-frequency fluctuations features by Kanghui Yu, Kanghui Yu, Shoujun Xu, Shishun Fu, Kelei Hua, Yi Yin, Qiang Lei, Jinwu Liu, Yunfan Wu, Guihua Jiang, Guihua Jiang

“…Nevertheless, there were no linear correlation between the ALFF values in children with ASD and clinical scales.ConclusionThe findings suggest an association of regional left brain dysfunction with ASD in preschoolers. The values of sALFF and dALFF, particularly in the middle temporal gyrus, could act as possible indicators for the early detection of ASD.…”
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IMPULSE OSCILLOMETRY FOR DIAGNOSIS OF EARLY CHANGES IN THE RESPIRATORY SYSTEM FUNCTIONAL STATE IN PATIENTS WITH MILD ASTHMA by N. M. Leontieva, I. V. Demko, E. A. Sobko, O. P. Ishchenko, I. A. Solov’yova

“…The objective of this work was to study opportunities of impulse oscillometry in diagnostics of early respiratory dysfunctions of ist most informative indicators correlating with parameters of spirometry and body plethysmography.Materials and methods. …”
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