Structural and functional myocardial abnormalities and arrhythmias in patients with type 1 diabetes complicated with ketoacidosis by N. V. Mukha, A. V. Govorin, D. N. Zajtsev, A. P. Filev

“…To study the structural and functional cardiac changes and arrhythmias in patients with type 1 diabetes (T1D) complicated with ketoacidosis.Material and methods. We analyzed 24-hour Holter monitoring data in 112 patients with T1D complicated with diabetic ketoacidosis (DKA). …”
Get full text

Nephroprotective peptides of Laennec® in the context of pharmacotherapy for nephro-hepato-metabolic disorders by O. A. Gromova, I. Yu. Torshin, A. N. Gromov, O. V. Tikhonova

“…Background. Renal-hepatic dysfunction, which often occurs in liver dysfunction, requires the use of effective and safe nephroprotective agents. …”
Get full text

Fosinopril – a drug of choice in chronic heart failure prevention and treatment by N. Yu. Khosyainova, V. M. Tsareva, O. V. Sukharukova, I. V. Milyagina

“…To study ACE inhibitor fosinopril effects on remodeling, diastolic filling of left and right ventricles (LV, RV), ectopic myocardial activity, heart rate variability, endothelial function, and microcirculation in patients with arterial hypertension (AH) and LV diastolic dysfunction (LVDD). To study fosinopril effects on clinical status, central hemodynamics, remodeling, LV and RV diastolic filling in patients with chronic heart failure (CHF) and LV systolic dysfunction (LVSD). …”
Get full text

Complex assessment of cardiovascular risk factors at Health Centres by M. V. Avdeeva

“…The prevalence of autonomic dysfunction or “Myocardium” parameter increase, as an isolated RF, reached 8,84% and 9,45%, respectively. …”
Get full text

Hypertensive encephalopathy, heart remodeling, and chronic heart failure by L. A. Geraskina, V. V. Mashin, A. V. Fonyakin

“…Stage I CHF (isolated diastolic dysfunction) was diagnosed in 65 (57.5%) patients, Stage IIA CHF – in 36 (31.9%) participants. …”
Get full text

ENDOTHELIAL ADHESIVE FUNCTION IN PATIENTS WITH ISCHEMIC HEART DISEASE COMPLICATED BY CHRONIC HEART FAILURE AND ATRIAL FIBRILLATION by A. N. Zakirova, E. R. Abdukova, N. E. Zakirova

“…To access the role of endothelial adhesive dysfunction in the development of atrial fibrillation (AF) in patients with ischemic heart disease (IHD) complicated by chronic heart failure (CHF).Material and methods. 111 patients with CHF class I–IV due to myocardial ischemia were included in the study. …”
Get full text

Structural and functional remodelling of left atrium in various localizations of myocardial infarction by K. G. Adamyan, A. L. Chilingaryan, L. R. Tumasyan

“…The most severe LV and LA dysfunction were registered in AMI. In PLMI, LA dysfunction was explained by the direct myocardial damage.…”
Get full text

CITED2 Mediates Metabolic Reprogramming in Renal Tubular Epithelial Cells via the AKT Signaling Pathway to Induce Sepsis-Associated Acute Kidney Injury by Deng R, Yang H, Zhong W, Zhou J, Huang G, Zeng K

“…CITED2 silencing attenuated TECs metabolic dysfunction and reduced inflammation, thereby protecting the kidney from injury. …”
Get full text

Multidimensional exploration of hydrogels as biological scaffolds for spinal cord regeneration: mechanisms and future perspectives by Chenxi Han, Chenxi Han, Jiao Jiao, Jiao Jiao, Chan Gong, Chan Gong, Jiatao Li, Jiatao Li, Min Zhao, Min Zhao, Xiao Lu, Xiao Lu

“…Spinal cord injury (SCI) is a severe condition that frequently leads to permanent disabilities and neurological dysfunction. Its progression is driven by a multifaceted pathophysiology, encompassing direct trauma, secondary injury cascades, and intricate cellular and molecular responses. …”
Get full text

The serum changes of vascular endothelial growth factor and tissue inhibitor metalloproteinase factors after a period of combined and aerobic physical activity in elderly men by Amir Delshad, Fateme Talashan

“…Background and Aims: Aging causes changes in health status, including endothelial dysfunction, angiogenesis disorder, and an increase in the prevalence of diseases. …”
Get full text

Acupuncture for post-cesarean pain and gastrointestinal function recovery: a meta-analysis and systematic review by Hejing Liu, Kehan Xing, Cai Liao, Jiapei Wang, Chenglin Tang, Siqin Huang

“…ObjectivePostoperative pain and gastrointestinal dysfunction are common complications after cesarean section, significantly affecting maternal recovery and quality of life. …”
Get full text

Inhibition of HDAC3 induces neuroprotection by activating the Npas4 signaling pathway following surgical brain injury in rats by Haiping Gu, Yating Gong, Muyao Wu, Mengying Shi, Jiejie Yu, Hongfei Zhu, Ya-ming Sun, Baoqi Dang

“…RGFP966 application can significantly improve brain edema and neurological dysfunction 24 hr after SBI, enhance autophagy, and reduce inflammation. …”
Get full text

Immunohistochemical assessment of epidermal growth factor receptor and prohibitin expression in “post-COVID” placentas: results of a comparative cross-sectional study by G.S. Manasova, Y.O. Stasii

“…SARS-CoV-2 infection during pregnancy is associated with certain changes in placental metabolism, and changes in the expression of placental proteins EGFR and PHB may be involved in the pathogenetic mechanisms of the placental dysfunction development. The limited sample size requires additional research.…”
Get full text

Is There Any Effect of Diagnostic Disease Activity Index on Current Myocardial Function in Pediatric Inflammatory Bowel Disease Patients? by Esra Polat, Elif Erolu, Nelgin Gerenli, Hasret Ayyıldız Civan

“…Aim:Inflammatory bowel disease (IBD): [Crohn’s disease (CD) or ulcerative colitis (UC)] is characterised by chronic inflammation with multisystemic effects. Myocardial dysfunction may occur during active disease due to increased inflammation. …”
Get full text

Study on the role of tissue-specific and non-specific autoantibodies, matrix metalloproteinase-3 and neuron-specific enolase enzymes in the exacerbation of autoimmune thyroiditis by R. R. Rahimova, A. M. Efendiyev, I. J. Shahverdiyeva, G. S. Dashdamirova, S. R. Guliyeva, U. H. Azizova

“…Elevated titers of anti-DNA autoantibodies may indicate an aggravation of the autoimmune process due to cellular structure damage, resulting in gland dysfunction. The findings also suggest that metalloproteinase-3, a marker predicting thyroid tissue damage, may negatively impact the immune response induction, ultimately affecting the activity of neuron-specific enolase. …”
Get full text

The Use of β-blockers in Patients with Ventricular Ectopic Heartbeat in the Early and Distant Postinfarction Period by N. M. Kulayets

“…Assessment of hemodynamic parameters in the process of patients with ST treatment has represented the marked trend and a further significant increase in ejection fraction and other contractile dysfunction forms correction. This positive trend was the most relevant in the application of carvedilol, a slightly less in patients treated with metoprolol and sotalol. …”
Get full text

Characteristics of endometrial receptivity in women with different endometrial thickness by N. V. Aganezova, S. S. Aganezov, K. E. Gogichashvili

“…Aim: to evaluate the expression of estrogen (ER) and progesterone (PR) receptors in the endometrium during the "implantation window" in women with a history of reproductive dysfunction with different endometrial thickness.Materials and Methods. …”
Get full text

Clinical features of the acute period of myocardial infarction with ST segment elevation in patients after reperfusion therapy by S. M. Kyselov, Yu. V. Savchenko

“…Aim: to determine the clinical features of the course of myocardial infarction with ST segment elevation in the acute period in patients after reperfusion therapy. Materials and methods. The clinical and instrumental examination data of 100 patients with ST-elevation myocardial infarction (STEMI) in the acute period were analyzed. …”
Get full text

Verrucous leukoplakia of the red border caused by the use of IQOS heated tobacco product (a case report) by H. I. Makurina, O. I. Мakarchuk, I. P. Dmytrenko, A. V. Holovkin, I. А. Sokolovska, A. S. Chornenka

“…Based on the literature analysis, it was found out that IQOS heated tobacco product and HEETS sticks can promote the development of such manifestations of oxidative stress and endothelial dysfunction as inflammation, infection, fibrosis, oncologic pathology and become one of initiating agents for the occurrence of red border verrucous leukoplakia. …”
Get full text

A preliminary follow-up study on irreversible electroporation therapy in older patients with prostate cancer by Zhi-Yu Xia, Jun Yang, Fan Xiao, Jin-Zhou Xu, Xing-Yu Zhong, Shao-Gang Wang, Qi-Dong Xia

“…Irreversible electroporation represents an innovative therapeutic approach that employs high-voltage electrical pulses to selectively eradicate tumor cells, potentially preserving vital normal tissue. Materials and methods This follow-up study included 11 older prostate cancer patients who underwent IRE therapy from November 2021 to December 2023. …”
Get full text