Management of Adverse Effects in Testosterone Replacement Therapy by Basheer Basheer, Vishal Ila, Rodrigo Barros, Francesco Mesquita, Leonardo Seligra Lopes, Victor Fernandes Negris Lima, Luciano A. Favorito, Ranjith Ramasamy

“…ABSTRACT Purpose: This narrative review aims to provide the most updated knowledge regarding the treatment of adverse effects secondary to testosterone replacement therapy (TRT), such as gynecomastia, cardiovascular and hematologic risks, prostate health risk, and liver dysfunction risks. Materials and Methods: An extensive literature review was conducted, incorporating guidelines from the American Urological Association and the Endocrine Society. …”
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Clinical and pathophysiological aspects of non-motor manifestations of Parkinson's disease by M. A. Nikitina, N. G. Zhukova, E. Yu. Bragina, V. M. Alifirova, I. A. Zhukova, D. E. Gomboeva, E. S. Kolupaeva, I. Zh. Zhalsanova

“…This survey comprises nonmotor manifestations of PD, such as: mood disorders (apathy, anxiety, depression), impulse control disorders (dopamine disregulation syndrome), sleep disorders (insomnia, excessive daytime sleepiness, bouts of sleepiness, conduct disorder in REM phase of sleep), autonomic disorders (constipation, enuresis, thermoregulatory dysfunction, cardiovascular disorders, orthostatic hypotension), and cognitive impairment.…”
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Effect of 8 weeks of high-intensity functional training (HIFT) on previous vascular factors and exercise enjoyment in women suffering from metabolic syndrome by Mina Behari Kia, Bahman Hasanvand

“…Introduction: Individuals with metabolic syndrome face a higher risk of developing cardiovascular disease compared to healthy individuals, attributed to endothelial dysfunction, increased blood lipids, and insulin resistance. …”
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Mental disorders in patients with cystic fibrosis by A. A. Klimenko, A. Yu. Aleksandrova

“…Cystic fibrosis (CF) is a genetic disease that leads to dysfunction of internal organs and significantly increases the risk of respiratory infections. …”
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Neglected and Large Defect of Extensor Hallucis Longus Tendon Injuries reconstructed by Double looping with Extensor Digitorum Longus by an Improvised Surgical Method by Makesh Ram Sriraghavan, Poornima Kumararja, Pavalan Louis

“…But in chronic cases or neglected EHL injuries, the patient develops EHL dysfunction causing a flexion deformity of the great toe at the level of the IP joint. …”
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Protein growth factors and myocardial remodeling in hypertension in men with psoriasis by V. A. Razin, Yu. N. Kurganova, A. S. Nesterov, I. M. Vorotnikov

“…Protein growth factors such as vascular endothelial growth factor and insulin-like growth factor are involved in the pathogenesis of hypertension and psoriasis, and endothelial dysfunction is also noted in these diseases. Despite extensive studies of these nosologies, there is still insufficient information about the nature of remodeling of the cardiovascular system in the case of a combination of these pathologies.Objective. …”
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Assessment of cardiac hemodynamics indicators in patients with arterial hypertension and non-alcoholic fatty liver disease depending on angiotensin II type 1 receptor A1166C gene p... by O. Ya. Babak, M. M. Zaitseva

“…According to our study results, no differences in left ventricular diastolic dysfunction were found depending on angiotensin II type 1 receptor (A1166C) gene polymorphism in the examined patients. …”
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The Role of Gut Microbiota in the Prevention or Development of Atherosclerosis – A Review by Marcin Początek, Michał Piotrowski, Piotr Serwicki, Szczepan Pośpiech, Jakub Prosowski

“… Aim of the study: This study aims to consolidate current knowledge on the role of gut microbiota in atherosclerosis, examining its mechanisms of action, the impact of dietary patterns on microbial composition, and emerging therapeutic interventions. Materials and methods: A systematic review of scientific literature was conducted through PubMed, Google Scholar, and other databases, focusing on diagnostic advancements, insights into the role of gut microbiota in atherosclerosis, and innovative therapeutic methods. …”
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A study of serum calcium, phosphorous and magnesium level in hypothyroid cases by Arun Dhungana, Naveen Shreevastva, Subash Pant, Baburam Pokharel

“…Conclusions: Our study, suggests that there was a significant change in the levels of serum calcium, phosphorous, and magnesium in thyroid dysfunction. Assessing the level of serum calcium and phosphorous can be fairly used as an index of bone resorption. …”
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The patient with cognitive impairment in practice of the general practitioner by Margarita A. Morozova, Elizaveta K. Kucherova, George E. Rupchev, Andrey A. Alekseev

“…The formulation of the seven items of the MCI 7 questionnaire was based on patients' complaints about those aspects of cognitive dysfunction that are found in MCI. The linguistic form of the questions was as close as possible to everyday speech, each question had to be answered either ”Yes” or ”No”. …”
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Vaginal Vault Prolapse by Azubuike Uzoma, K. A. Farag

“…Vault prolapse repair rely on either the use of patient's tissue or synthetic materials and can be carried out abdominally or vaginally. …”
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Immediate and long-term results of microsurgical resection of tentorial meningiomas by R. A. Sultanov, R. S. Dzhindzhikhadze, A. V. Polyakov, V. S. Gadzhiagaev, A. D. Zaitsev, E. I. Salyamova

“…In 2 (8.3 %) patients, dysfunction of the abducens nerve was observed, in 3 (12.5 %) – impaired hearing or deafness, in 5 (20.8 %) – ataxia aggravation. postoperative complications developed in 2 (8.3 %) patients. …”
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Fluoxetine Versus Citalopram in Improving Post-stroke Motor Function: A Comparative Single-blind Clinical Trial by Payam Saadat, Romina Hamzehpour, Fatemeh Karimi, Pouyan Ebrahimi, Mahmoud Haji Ahmadi

“…Conclusion: Considering motor dysfunction after ischemic stroke, fluoxetine and citalopram treatments can be a suitable treatment suggestion to improve the motor status of patients and thus improve their health.…”
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Prevalence of urinary incontinence and its associated predictor and Self-care behavior among the elderly females in Chaiyaphum Province, Thailand: Cross-sectional study by Patchareepon Chompoowisate, Sumattana Glangkarn, Chaloemporn Namyota

“…MATERIALS AND METHODS: This cross-sectional descriptive research was conducted in a community context using semi-structured interviews as data collection methods. …”
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COVID-19 Symptomatology from the Otorhinolaryngology Perspective: Survey from Tertiary Care Center by Raj Tajamul Hussain, Mayank Yadav, Jasdeep Monga

“…The most common otorhinolaryngologic symptoms were sore throat, headache and olfactory dysfunction with respective frequencies of 19.52%, 17.03% and 14.81%. …”
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Integrating systemic inflammation and liver biomarkers: prognostic implications of the ferritin index in heart failure by Ching-Hui Huang, Chew-Teng Kor, Chia-Chu Chang

“…Background Heart failure (HF) is increasingly recognized as a multisystem syndrome involving systemic inflammation and metabolic dysfunction in addition to cardiac and hepatic impairment. …”
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Prognostic Value of Systemic Immune-inflammatory Index in Pulmonary Embolism by Mehmet Mermer, İlker Kaçer, Ahmet Çağlar

“…Lactate, age, right ventricular dysfunction (RVD), and SII ≥0.904 were independent risk factors for 30-day mortality in PE (p<0.05). …”
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Prediction of tension-type headache risk in adolescents by K. A. Stepanchenko

“…To develop a method for prediction of tension-type headache occurrence in adolescents. Materials and methods. 2342 adolescent boys and girls at the age of 13-17 years in schools of Kharkiv were examined. …”
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Effect of alprostadil combined with beraprost sodium tablet sequential therapy in early mutation and long term survival of arteriovenous fistula by YU Chong, YAN Jian-jun, YU Yang, HE Fan, Xiong Wen-fang, LIU Wei

“…Objective To observe the effect of alprostadil combined with beraprost sodium tablet sequential therapy in early mutation and long term survival of arteriovenous fistula(AVF).Methods Weretrospectively analyzed 312 uraemia patients who received AVF operation first time between January 2013 and March 2014.All patients were given radialartery-cephalic vein standard fistulation.Forty-six patients were administered alprostadil(20 μg i.v.drip for 3 days in hospital) combined with beraprost sodium tablet(20 μg P.O.for 3 months for outpatient) sequential therapy as study group.Forty-six patients without treatment of alprostadil or beraprost sodium were included into control group.These two groups had the same clinical materials,such as age,the diameter of artery and vein before operation,primary disease constitution rate.The fistula dysfunctional rate in 1 year,fistula mutation time,average fistula flow volume and arterial end diastolic velocity 1 year postoperation were assessed.Results In study and control groups,the fistula dysfunctional rate was 10.9%and28.2%respectively(P=0.035 5),the mean maturation time was(42.1±6.5)and(55.5±5.8) days respectively(P<0.001),the mean blood flow was(789 ± 101) and(556 ± 132) mL/min respectively(P<0.001),and the arterial end diastolic velocity was(151.5 ± 14.5) and(113 ± 20.1) cm/s respectively(P<0.001).Conclusions Our data indicated that the sequential therapy of alprostadil combined with beraprost sodium tablet is effective and safe for the prevention of primary AVF failure in hemodialysis patients and early fistula dysfunction.…”
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Association of smoking with hearing loss—a hospital based retrospective case–control study by Aishwarya T. Bhatt, Garima Upreti

“…Tobacco smoke-induced middle ear mucosal edema and Eustachian tube dysfunction and edema can also contribute to hearing loss. …”
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