In vivo assessment of endothelial function in small animals using an infrared pulse detector by Cyuan-Cin Liu, Wei-Min Liu, Hsien-Tsai Wu, Chien-Hsing Wang, An-Bang Liu

“…Objective: Endothelial dysfunction is the earliest change in atherosclerosis. …”
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Heart valve calcification in patients with coronary heart disease by S. A. Dovgolis, I. Yu. Kucherova, E. A. Kozlov, I. G. Fomina

“…Mitral and aortic valve calcification, regurgitation, ejection fraction, diastolic dysfunction, left cardiac chamber sizes, and atherosclerosis risk factors were studied. …”
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Pathogenetic role of the autonomic nervous system in arterial hypotension cardiac remodeling in young women by V. M. Baev, Т. Yu. Agafonova

“…We identified a restrictive type of diastolic dysfunction in women with parasympathicotonia.Conclusion. …”
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NEPHROPROTECTIVE EFFECTS OF LISINOPRIL IN THE THERAPY OF HYPERTENSIVE PATIENTS WITH OBESITY by S. G. Shulkina, Е. N. Smirnova

“…To investigate the dynamics of biomarkers of early renal damage in patients with hypertension (HT) and obesity treated with lisinopril and diet therapy.Material and methods. The study included 120 people aged 25 to 55 years (90 patients with HT in combination with obesity and 30 HT patients without obesity). …”
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Evaluation of the Psychometric Properties of the Scale A-ONE: An Italian Cross-Sectional Study by Margherita Cerone, Marco Tofani, Giovanni Fabbrini, Giulia Marcellini, Anna Berardi, Claudia Conti, Rita De Santis, Donatella Valente, Giovanni Galeoto

“…This study is aimed at validating the A-ONE scale in an Italian population with Central Nervous System (CNS) dysfunction. Material and Methods. Between May and November 2018, people aged between 60 and 90 with CNS dysfunction were recruited in a hospital in Rome, Italy. …”
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Rational Pharmacological Prophylaxis of Gestation Process Complications in Pregnant Women with Varicose Disease by Markin L., Shatylovytch K.

“…Actually, one of the gestating complications of chronic venous insufficiency is the formation of secondary placental dysfunction with clinical implementation in the form of fetal distress, fetal growth retardation syndrome (FGRS), preeclampsia (PE). …”
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The technique of three-component regional blockade of the anterior neck region as a component of anesthesia during operations on the thyroid and parathyroid glands by A. A. Alekseev, A. G. Yavorovskiy, E. N. Prazdnikov, A. M. Ovechkin, D. V. Dospekhov, V. S. Vakhromkin, E. A. Sozonova, E. V. Batulina, A. A. Maksimova, E. N. Zolotova

“…The use of various regional blockades as a component of general anesthesia reduces the risk of postoperative complications such as intense pain syndrome, postoperative nausea and vomiting, and postoperative cognitive dysfunction. The study is devoted to the development and description of the technique of regional anesthesia of the anterior surface of the neck during operations on the thyroid and parathyroid glands under ultrasound navigation.The objective was to develop a safe and effective technique of regional anesthesia for operations on the thyroid and parathyroid glands under ultrasound navigation.Materials and methods. …”
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Age-Specific Clinical and Laboratory Features and Renal Involvement in Children with MIS-C: A Single Tertiary Centre Experience from Vojvodina by Borko Milanović, Vesna Stojanović, Gordana Vijatov-Ðurić, Marijana Savin, Andrea Ðuretić, Jelena Kesić, Nenad Barišić, Ognjen Ležakov, Ivana Vorgučin, Gordana Vilotijević-Dautović, Katarina Koprivšek

“…The 7–12-year age group showed the highest rate of organ dysfunction. In adolescents (13–18 years), neurological symptoms, the highest BMI values, the greatest prevalence of comorbidities, leukopenia, lymphopenia, and elevated GGT levels were observed. …”
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Serum adipokine concentrations in patients with type 2 diabetes: the relationships with distribution, hypertrophy and vascularization of subcutaneous adipose tissue by Vadim V. Klimontov, Dinara M. Bulumbaeva, Nataliya P. Bgatova, Iuliia S. Taskaeva, Nikolay B. Orlov, Olga N. Fazullina, Michael Y. Soluyanov, Sergey V. Savchenko, Vladimir I. Konenkov

“…Academy of Sciences, Novosibirsk, Russia 2Novosibirsk State Medical University, Novosibirsk, Russia BACKGROUND: Adipose tissue (AT) dysfunction plays an important role in metabolic disorders in obesity and type 2 diabetes. …”
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A method for the biological age of the heart determination by L. A. Bodretska, I. S. Shapovalenko, A. V. Pisaruk, I. A. Antoniuk-Shchehlova, O. V. Bondarenko, S. S. Naskalova, V. B. Shatylo

“…Significant increase in atrial size with age, development of diastolic dysfunction, increase in left and right ventricular myocardial infarction were found. …”
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Early – versus late-onset preeclampsia: differences in risk factors and birth outcomes by Markin L., Medvyedyeva O.

“…EOP starts with a failure to transform the maternal spiral arteries, subsequently followed by alterations of the villous trophoblast, lead to severe placental lesion (early placental dysfunction), hypoxia of the placenta and fetus, the failure of compensatory mechanisms, an increase endothelial dysfunction markers. …”
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The impact of chronic heart failure on heart remodeling in patients with atrial fibrillation by V. А. Lysenko, V. V. Syvolap

“…AF patients with signs of CHF had decreased LV EF (55.58 ± 14.65 % vs. 65.44 ± 10.87 %; P = 0.006), systolic velocity of the medial fibrous ring of the mitral valve S (6.92 ± 2.41 cm/s vs. 8.40 ± 2.03 cm/s; P = 0.015), and significantly higher values of TEI RV (0.58 ± 0.16 c. u. vs. 0.48 ± 0.11 c. u.; P = 0.011), but decreased TAPSE values (16.22 ± 4.60 mm vs. 19.54 ± 5.00 mm; P = 0.067), indicating more pronounced systolic dysfunction of both ventricles. Conclusions. Comorbidity of CHF and AF in patients is accompanied by the increased percentage of eccentric hypertrophy (49 %; P = 0.027), more pronounced systolic dysfunction of the left and right ventricles, increased LVEDP, PCWP, systolic pressure in the pulmonary artery, dilation of the inferior vena cava.…”
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The Management of Cardiometabolic Risk in MAFLD: Therapeutic Strategies to Modulate Deranged Metabolism and Cholesterol Levels by Annalisa Pezzoli, Ludovico Abenavoli, Marialaura Scarcella, Carlo Rasetti, Gianluca Svegliati Baroni, Jan Tack, Emidio Scarpellini

“…<i>Materials and Methods:</i> For all these reasons, we conducted a narrative review of the literature, and we focused on metabolic dysfunction related to MAFLD, with a special regard for cholesterol metabolism. …”
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Pathogenetic and prognostic significance of inflammation and altered ADAMTS-13/vWF axis in patients with severe COVID-19 by V. O. Bitsadze, J. Kh. Khizroeva, J.-Ch. Gris, S. Schulman, A. S. Shkoda, M. V. Tretyakova, N. A. Makatsariya, E. V. Slukhanchuk, L. L. Pankratyeva, M. I. Petrovskiy, I. V. Mashechkin, D. V. Blinov, V. I. Tsibizova, Z. K. Gadaeva, S. S. Panshin, N. V. Samburova, A. D. Makatsariya

“…The activation of innate immune cells including neutrophils results in formation of neutrophil extracellular traps (NETs) and myeloperoxidase (MPO) release that, in turn, contributes to spread of inflammation and microvascular thrombosis.Aim: to evaluate a pathogenetic role and predictive significance for serum markers of inflammation, endothelial dysfunction and hemostatis activation such as vWF, ADAMTS-13 and MPO for in-hospital mortality in severe COVID-19 patients requiring mechanical lung ventilation.Materials and Methods. …”
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The use of microvascular endothelial function indicators to calculate functional age of the microcirculation system by O. V. Korkushko, V. B. Shatylo, O. V. Bondarenko, A. V. Pysaruk, I. A. Antonyuk-Shchehlova, S. S. Naskalova, H. V. Duzhak, L. A. Bodretska, I. S. Shapovalenko

“…To find out the possibility of using microvascular endothelial function indicators to determine the biological age (BA) of a person. Materials and methods. 390 patients aged 20–29 years (n = 31), 30–39 (n = 22), 40–49 (n = 45), 50–59 years (n = 72), 60–69 years (n = 129) and 70–79 years (n = 91) were examined. …”
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Рrediction risk factors of gastroesophageal reflux disease in children and adolescents with chronic gastroduodenal pathology by L. M. Boiarskа, К. А. Ivanova

“…The main risk factors of its development are acid-peptic factor, Н.pylori, the autonomic nervous system dysfunction, rapid growth, heredity, burdened perinatal history, dysplasia of connective tissue structures (DCTS), environmental factors and lifestyle. …”
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Clinical Features and Inhospital Outcomes of Takotsubo (Stress) Cardiomyopathy: Ten Years’ Experience from a Tertiary Care Center in South India by Amit Mandal, John Jose, Oommen K. George, Paul V. George, Viji Samuel Thomson, George Joseph

“…Background: Takotsubo cardiomyopathy is a syndrome which is characterized by transient regional systolic dysfunction, principally, of the left ventricle (LV), mimicking myocardial infarction (MI), but in the absence of angiographic evidence of obstructive coronary artery disease or acute plaque rupture. …”
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Clinical efficacy of gliclazide with modified release after myocardial infarction in patients with concomitant type 2 diabetes by N. S. Mykhailovska

“…Objective: to study the effectiveness of gliclazide modified release in patients with Q- myocardial infarction with concomitant type 2diabetes mellitus by its effect on the clinical course of the disease, glucometabolic control and humoral parameters during 12 months of observation. Materials and Methods: we examined 99 patients with Q- myocardial infarction with metabolic syndrome and concomitant type 2diabetes mellitus, 52 men (52.53%) and 47 women (47.47%), average age (62,9 ± 2, 05) years. …”
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Optimizing the treatment for gastroesophageal reflux disease in young people: the role and place of rebamipide by I.M. Skrypnyk, I.M. Gorodnytska, G.S. Maslova, B.M. Fylenko

“…Objective: to evaluate the effect of rebami­pide on the restoration of the esophageal protective barrier in the presence of erosive or non-erosive forms of gastroesophageal reflux disease in young patients. Materials and methods. Thirty young patients with GERD aged 18 to 45 years were examined. …”
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11-amino acid peptide imitating the structure of erythropoietin α-helix b improves endothelial function, but stimulates thrombosis in rats. by M. V. Korokin, V. O. Soldatov, A. A. Tietze, M. V. Golubev, A. E. Belykh, M. V. Kubekina, O. A. Puchenkova, T. A. Denisyuk, V. V. Gureyev, T. G. Pokrovskaya, O. S. Gudyrev, M. A. Zhuchenko, M. A. Zatolokina, M. V. Pokrovskiy

“…Endothelial dysfunction was modulated by a 7-days intraperitoneal administration of L-NAME at the dose of 2.5 mg/100 g. …”
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