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Structural and functional changes of the heart in patients with coronary heart disease who have had coronavirus disease COVID-19
Published 2024-06-01“…The aim of the study: to investigate the effect of the previous COVID-19 coronavirus disease on the features of cardiac remodeling in patients with coronary heart disease (CHD). Materials and methods. 71 patients with CHD were involved in the study: stable angina pectoris II–III FC (age 69.0 (64.0; 76.0) years): 1 group (main) – 31 patients with CHD in long COVID-19 period; group 2 (comparison) – 40 patients with CHD without a history of COVID-19. …”
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1262
PREDICTORS OF HYPOXIC ISCHEMIC ENCEPHALOPATHY IN NEWBORNS
Published 2018-01-01“…Goal of the study: to study the level of markers of the system fetal inflammatory response and endothelial dysfunction in the umbilical blood of full-term newborns survived after intranatal asphyxia. …”
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1263
Post-Transplant Liver Monitoring Utilizing Integrated Surface-Enhanced Raman and AI in Hepatic Ischemia-Reperfusion Injury Animal Model
Published 2025-05-01“…This study explores the integration of surface-enhanced Raman spectroscopy (SERS) with artificial intelligence (AI) to improve diagnostic accuracy for liver IR injury.Materials and Methods: IR injury was induced using a mouse model, and histopathological and hepatic functional evaluations were conducted alongside SERS measurements. …”
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1264
Peripheral blood heat shock protein 27 correlates with information processing speed and executive function, potentially serving as a marker for mild cognitive impairment in patient...
Published 2025-05-01“…Abstract Background and aims Previous study found that interleukin 1β (IL-1β) is associated with diabetic cognitive dysfunction. Heat shock protein 27 (HSP27) is one of the factors related to IL-1β associated inflammation. …”
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1265
Rectal Reconstruction after Total Mesorectumectomy: Functional Outcomes and Quality of Life
Published 2021-10-01“…The ease of implementation and irrelevance of evacuatory dysfunction in side-to-end anastomosis make it a superior choice over end-to-end surgery.…”
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1266
Correlations between Steady-State Pattern Electroretinogram and Humphrey Visual Field Analyzer Global Indices and Their Associations with Retinal Ganglion Cell Layer-Inner Plexifor...
Published 2024-01-01“…Materials and Methods. This was a prospective cohort study of GS patients who were identified based on optic disc appearance with normal HFAs. …”
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1267
Investigating the relationship between plasma natriuretic peptide levels and chronic kidney disease stages in patients with and without concurrent heart failure
Published 2025-01-01“…Materials and Methods: This cross-sectional study was conducted at the Institute of Medical Science, BHU, a tertiary care hospital at Varanasi, Uttar Pradesh. …”
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1268
Protective role of 3-oxypyridine derivatives in rats’ steroid-induced osteoporosis associated with reduced oxidative stress and recovery of nitric oxide formation
Published 2023-05-01“…From the point of view of the mechanisms for the implementation of pathogenetic links in the development of steroid-induced osteoporosis considered in the paper, the increased risk of the oxidative stress in osteoblasts, as well as the development of the vessels endothelial dysfunction of the microcirculatory bloodstream in the bone tissue, are of particular interest. …”
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1269
Increased left ventricular mass as a marker of left ventricular hypertrophy in normotensive type 2 DM patients
Published 2025-03-01“…Abstract Background Diabetes is considered to be one of the most important metabolic conditions causing left ventricular (LV) dysfunction, one of which is Left ventricular hypertrophy (LVH). …”
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1270
Usefulness of the Córdoba Equation for Estimating Body Fat When Determining the Level of Risk of Developing Diabetes Type 2 or Prediabetes
Published 2025-03-01“…However, recent evidence suggests that the adipose tissue composition and distribution play a more critical role in metabolic dysfunction than the total body weight or body mass index (BMI). …”
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1271
Pim3 up-regulation by YY1 contributes to diabetes-induced cardiac hypertrophy and heart failure
Published 2025-02-01“…This study aims to investigate whether Pim3 is involved in DM-induced cardiac hypertrophy and HF and to elucidate its underlying mechanisms.Materials and Methods: DM was induced in mice by intraperitoneal injection of streptozotocin. …”
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1272
Features of endocrine status in adolescents with multiple sclerosis
Published 2025-06-01“…Adolescents with higher cortisol levels at baseline showed a lower severity of motor dysfunction (r=–0.59, p<0.001) and disability as measured by the Expanded Disability Status Scale (EDSS) (r=–0.49, p=0.004). …”
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1273
Non-Alcoholic Fatty Liver Disease in Cardiac Patients with Overweight and Obesity
Published 2019-01-01“…NAFLD is accompanied by endothelial dysfunction and a change in the most significant parameters of cardiac and vascular remodelling. …”
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1274
Muscle Strength and Cardiovascular Health in MASLD: A Prospective Study
Published 2025-02-01“…This study aimed to explore the relationships between clinical indicators of MASLD and sarcopenia, cardiorespiratory fitness, fatigue, and mood. <i>Materials and Methods</i>: The study involved 60 participants, including 28 healthy controls and 32 with MASLD, categorized into two disease subgroups: 15 with MASL and 17 with metabolic dysfunction-associated steatohepatitis (MASH). …”
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1275
Pharmacological effects of a new soluble guanylate cyclase stimulator in experimental pulmonary arterial hypertension
Published 2023-04-01“…GRS also alleviated endothelial dysfunction in animals with experimental PAH.…”
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1276
The Impact of Acquired Hypothyroidism on the Growth and Metabolic Profiles of Pediatric Patients: A Retrospective Monocentric Study
Published 2025-02-01“…Additionally, we examined possible differences in lipid and glucose metabolism between the two groups. <b><i>Materials and Methods</i>:</b> We collected and analyzed data from the electronic medical records of 108 patients who were regularly followed up for thyroid dysfunction at the Pediatric Endocrinology Unit of the <i>Fondazione Policlinico Universitario A. …”
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1277
Evaluation of Chlorogenic Acid in Parkinson’s Disease Model: An In-vitro Study in 6-OHDA Induced SH-SY5Y Cell Line
Published 2025-06-01“…Introduction: Parkinson’s Disease (PD) is the most common neurodegenerative movement disorder. Mitochondrial dysfunction is a key pathological driver of PD. Pharmacological agents used in PD are not disease-modifying therapies and do not influence mitochondrial activity. …”
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Experimental faecal peritonitis alters response to 5-hydroxytryptamine in mesenteric lymphatic vessels
Published 2020-09-01“…In experimental faecal peritonitis, alterations in lymphatic vessels are reminiscent of those in blood vessels. Endothelial dysfunction disturbs the response of lymphatic vessels to 5-HT.…”
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Clot waveform analysis of prolonged activated partial thromboplastin time in various disorders
Published 2025-01-01“…The clotting data is processed to obtain derivatives. Materials and Methods: This observational study analyzed 80 samples including 20 samples from normal healthy individuals as control. …”
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Analysis of Creatinine Clearance in Patients on Antimicrobial and Analgesic Therapy
Published 2019-07-01“…Observation and Results: On analyzing the drugs causing renal impairment out of 1200 participants, it was found that among analgesics diclofenac (52%) and among antibiotics, aminoglycosides (61%), were more commonly resulting in renal dysfunction. Conclusion: According to the present study, it is clear that precaution has to be taken before initiating antimicrobials and analgesic therapy, as they are often nephrotoxic.…”
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