SIRT1/PGC-1α-mediated mitophagy participates the improvement roles of BMAL1 in podocytes injury in diabetic nephropathy: evidences from in vitro experiments by Yanxia Rui, Yinfeng Guo, Linying He, Min-er Wang, Henglan Wu

“…Abstract Background Dysfunction in podocyte mitophagy has been identified as a contributing factor to the onset and progression of diabetic nephropathy (DN), and BMAL1 plays an important role in the regulation of mitophagy. …”
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Clinical characteristics of the respiratory and cardiovascular systems in patients with combination of chronic obstructive pulmonary disease and heart failure by I. I. Vyshnyvetskyy, L. S. Kholopov, V. O. Batashova-Halynska

“…The aim of our work was to assess the respiratory and cardiovascular systems of patients with a combination of chronic obstructive pulmonary disease (COPD) and congestive heart failure (CHF). Materials and methods. The study included 177 patients who had been diagnosed COPD by criteria GOLD. …”
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Correlation between Post-COVID-19, Chemosensitive Function, Blood Group, and Oral Health-Related Quality of Life by Rehab Abdulwahab M. Alabsi, N. C. Sandeepa, Rema Tariq Misfer, Majdah Mahmood Alraqdi, Mohammed Ibrahim M. Hamdi

“…Several studies reported chemosensitive dysfunction in the olfactory and gustatory domains following coronavirus disease 2019 (COVID-19). …”
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Acute changes in left atrial appendage function with premature ventricular complexes by Suresh Kumar Sukumaran, Anish Bhargav, Sridhar Balaguru, Avinash Anantharaj, Santhosh Satheesh, Raja J. Selvaraj

“…Objectives: Left atrial appendage (LAA) dysfunction is a risk factor for stroke. Evidence shows that frequent premature ventricular complexes (PVCs) are associated with embolic stroke. …”
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Implementation of pro- and anti-inflammatory mechanisms of sirtuin-1 in patients with chronic obstructive pulmonary disease and chronic coronary syndrome and their combination by Ya. V. Chobanu, T. O. Ilashchuk

“…To study changes in the levels of serum endothelial nitric oxide synthase (NOS3/eNOS) and sirtuin 1 (SIRT1) in patients with a combined course of COPD and CCS and with COPD or CCS alone. Materials and methods. In order to study endothelial dysfunction and the role of SIRT1 in the processes of its development, we examined 60 patients with combined course of COPD and with CCS or COPD alone. …”
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Assessment of endothelial function and arterial rigidity in patients with type 1 diabetes at different stages of diabetic nephropathy by Evgenia Pavlovna Kosobyan, Ivona Renata Yarek-Martynova, Alexander Sergeevich Parfenov, Lyubov' Leonidovna Bolotskaya, Marina Vladimirovna Shestakova

“…Assessment of vascular stiffness and endothelial function in patients with type 1 diabetes at different stages of diabetic nephropathy and without it. Materials and methods. We examined 93 patients with DM1 aged 18 to 40 years, and disease duration of more than 5 years. …”
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A study of the association of thyroid-stimulating hormone levels with microvascular complications in type 2 diabetes mellitus patients at a tertiary care center by Somnath B, Pooja Shashidharan, Manish Pangi

“…Materials and Methods: A total of 50 T2 DM patients were enrolled in this cross-sectional study. …”
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Symbiotic anti-oxidant, anti-glycation, and anti-inflammatory qualities of a combination of thiamine and niacin protected type-2 diabetic male rats against both macro and micro-vas... by Sina Mahdavifard, Hamid Reza Malekzadeh

“…Metabolic profile and renal dysfunction parameters were assessed. Additionally, various glycation, oxidative stress, and inflammatory markers were measured.Results: The treated group with both vitamins showed the lowest blood sugar and insulin resistance indices, cardiovascular indices, renal dysfunction parameters, hepatic NF-kβ expression, oxidative stress, inflammatory and glycation markers, and the highest anti-oxidant and anti-glycation markers, β cell activity, and insulin sensitivity. …”
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P-70 ALCOHOL CONSUMPTION RECURRENCE IN LIVER TRANSPLANT PATIENTS WITH ALCOHOLIC CIRRHOSIS: HEALTH AND SOCIAL IMPACT by Fernando Cairo, Lucia Navarro, Ignacio Roca, Ana Saracho, Nicolas Dominguez, Omar Galdame, Manuel Barbero

“…Lower adherence to post-transplant treatment and higher graft dysfunction rates were significant in the recurrence group. …”
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High-Grade Late Urinary Toxicity Following Salvage Radiotherapy After Radical Prostatectomy: A Retrospective Cohort Study by Seung-Kwon Choi, Myong Kim, Sang Mi Lee, Cheryn Song, Jun Hyuk Hong, Choung-Soo Kim, Hanjong Ahn

“…Purpose To find out the incidence and predictors for late high-grade genitourinary (GU) toxicity following salvage radiotherapy (SRT), we investigated the consecutive patients who were treated with SRT after radical prostatectomy. Materials and Methods Patients who underwent SRT for biochemical recurrence after radical prostatectomy were reviewed. …”
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Concomitant cholelithiasis and acute (chronic) pancreatitis after thyroidectomy: case report by S. N. Styazhkina, E. V. Korovkina, A. G. Gevorkyan, Yu. V. Moskvina

“…In the study evaluating cases of concomitant hypothyroidism and chronic pancreatitis, the examination of patients with primary hypothyroidism revealed signs of pancreatic dysfunction in 64.1% of patients. Pancreatic dysfunction manifests itself with various changes in exocrine and endocrine functions and aggravates with hypothyroidism progression.Conclusion. …”
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Assessment of left ventricle myocardial performance index (Tei index) by myocardial tissue Doppler imaging and its correlation with serum thyroid-stimulating hormone levels and ath... by Amratansh Varshney, Satyajit Singh, Amritava Ghosh, Surendra Kumar Naik, Abhishek Kumar, Chandraprakash Thakur, Muneshwar Kumar, Nupur Goyal, Nabodoy Majumder, Rounak Kumar, Muhammad Rihas Rasheed

“…Conclusion: Subclinical hypothyroid patients have significant subclinical cardiac dysfunction (as determined by the Tei index) and dyslipidemia. …”
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Dynamic changes of heart structural and functional condition in patients with acute myocarditis by S. V. Сherniuk

“…It was found that the debut of AM was characterized by the presence of active inflammatory process according to the cardiac MRI - edema and hyperemia of the myocardium were detected in 54.0 % and 70.2 % of cases, respectively, followed by LV dilation and systolic dysfunction as well as by a significant decrease in longitudinal and circumferential LV global systolic strain. …”
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Clinical Characteristics, Seasonal Variation, Outcome and Disturbance of Taste and Smell in Cases of COVID-19 by Sumera akram, Muhammad Ahmed Khan, Saeed Akhtar Khan Khattak, Muhammad Ameen Khan, Muhammad Sajid Hussain, Bakhtawar Mustajab

“…Olfactory and taste dysfunction (anosmia and aguesia) was seen commonly in COVID-19 patients.…”
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Experience of the treatment of combat injuries of the maxillofacial area with titanium implants in the conditions of modern war by D. V. Ivchenko, S. D. Varzhapetian, O. M. Mishchenko, O. V. Sydor, Yu. M. Petrenko, Ye. V. Yatsun, T. V. Strohanova

“…The most common functional disorders as a result of injury were paralysis of the facial muscles and mandibular dysfunction which were observed in 100 % of our cases. …”
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Steatotic liver disease: radiological and ultrasound point of view by Alexey V. Borsukov, Daria Yu. Shestakova

“…Materials and methods. Five hundred forty nine patients were examined – 252 (45.9%) men, 297 (54.1%) women aged 18 to 78 years. …”
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Arterial blood pressure in schoolchildren, who were born after caesarian section by S. V. Popov, T. Yu. Loboda, O. I. Smiyan, E. K. Redko, I. E. Zaitsev

“…They were hospitalized in the pediatric department with a diagnosis of vegetative dysfunction and with complaints of periodic increase in blood pressure. …”
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Short- and long-term outcomes of patients with anterior vaginal wall prolapse after abdominal paravaginal cystocele repair by Kazila Bhutia, Xinyi Li, Jun Long Ernest Ong, Keryi Wong, How Chuan Han, Hong Liang Chua

“…Objective: Pelvic organ prolapse (POP) is a common condition for women, causing urinary dysfunction, discomfort due to the lump at the introitus, sexual dysfunction and difficulty with bowel emptying. …”
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Premorbid factors of early post-stroke cognitive impairment by A. А. Grishina, A. M. Tynterova, Y. E. Skalin

“…The aim of this study is to identify and substantiate early cognitive dysfunction in patients with brain damage in the acute period of ischemic stroke.Materials and research methods. …”
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Coexistent Coronary Artery Disease in Patients Undergoing Permanent Pacemaker Implantation - A Study from Major Center in North Eastern India by Bornali Dutta

“…Patients undergoing PPI with coexisting CAD were predominantly males and had a statistically significant increase in the incidence of dyslipidemia and LV systolic dysfunction. There was also increase in the incidence of hypertension, diabetes, and smoking in the CAD group though statistically not significant.…”
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