The Role of "Biotics" in the Modulation of the Intestinal Microbiota in Metabolic-Associated Steatotic Liver Disease by G. Fadieienko, О. Gridnyev

“…This determines the active development of such a direction as the modulation of the intestinal microbiota (primarily using pre-, pro-, post- and synbiotics) in this category of patients to influence both the development of hepatic steatosis and the progression to metabolic dysfunction-associated steatohepatitis. The aim of the study. …”
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The use of N-acetylcysteine to prevent further progression of preeclampsia by I Wayan Agung Indrawan, Leny Farida

“…The generation of free radicals in the placenta leads to endothelial dysfunction, which contributes greatly in preeclampsia. 2. …”
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Features of cerebral hemodynamics and vascular autoregulation in chronic cerebral ischemia by O.A. Kozyolkin, S.V. Yarkova

“…Recent years, the importance of the development of vascular disease is provided by endothelial dysfunction. The endothelium synthesizes active substances. …”
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DIAGNOSIS OF POST COVID-19 DISORDERS IN THE FUNCTION OF THE ENDOTHELIUM by Sviatoslav Ya. Kostiv, Ihor K. Venher, Boryslav P. Selskyi, Olga I. Kostiv, Andriy R. Vayda, Nazar I. Herasymiuk, Ihor I. Loyko

“…Post-COVID-19 infection survivors in 2021–2022 (n = 502) underwent a Flow-Mediated Dilation (FMD) test of upper arm occlusion by the brachial artery. Materials and methods. In the non-invasive study, endothelial dysfunction (ED) was induced with a pneumatic cuff, thereby inflicting compression only on the distal circulation with reactive hyperemia. …”
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Association of the Fractalkine Level with Non-modifiable and Modifiable Factors of Cardiovascular Risk, the Severity of the Atherosclerotic Lesions of the Coronary Vessels by Lopina N.

“…The purpose of research is to evaluate the association of fractalkine level with non-modifiable and modifiable factors of cardiovascular risk, and the severity of the atherosclerotic lesions of the coronary arteries. Materials and Methods. 131 patients with coronary artery disease (CAD) were examined. …”
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Relationship between the expression level of microRNA and the features of clinical course of the gallbladder and Оddi's sphincter functional disorders in children by O. Ye. Abaturov, V. L. Babуch

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Prevention of Postischemic Neurological Deficit by Modulating the Cerebral Cell Expression of ADP-Ribosyl Cyclase (Experimental Study) by A. A. Fursov, A. B. Salmina, S. V. Mikhutkina, L. D. Zykova, N. A., Malinovskaya, A. V. Morgun, D. I. Laletin, M. A. Fursov, G. V. Yudin, N. A. Shnayder, S. V. Shakhmaeva

“…Neuroprotection and prevention of postischemic cognitive dysfunction were achieved by the use of y-interferon as a modifier of the brain cell expression of CD38/ADP-ribosyl cyclase.…”
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Structural and functional changes of the heart and electrical disorders in patients with coronary artery disease with concomitant anemia by M. O. Konovalova, N. S. Mikhailovskaya

“…The patients of both groups mostly showed diastolic dysfunction type 1, however, in the main group, there was a tendency to increase the number of patients with diastolic dysfunction type 2 and type 3. …”
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EVALUATION OF THE MITOCHONDRIA RESPIROMETRIC FUNCTION IN THE CONDITIONS OF PATHOLOGIES OF VARIOUS GENESES by A. V. Voronkov, D. I. Pozdnyakov, S. A. Nigaryan, E. I. Khouri, K. A. Miroshnichenko, A. V. Sosnovskaya, E. A. Olokhova

“…The aim of the paper is to assess the change in the mitochondrial respirometric function under conditions of various pathologies.Materials and methods. The study was performed on male Wistar rats. …”
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Psychopersonal characteristics of women with varying degrees of menopausal disorders by N. S. Lutsenko, O. D. Mazur, O. S. Shapoval, L. I. Zvarich, N. F. Efimenko

“…Menopausal disorders of varying severity, increased anxiety and neuroticism, sexual dysfunction affected the quality of life of patients. …”
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Formation of myofаscial pain syndrome and its correction in patients with tension headache by A.V. Vesnin, O.L. Tovazhnianska

“…When diagnosing TH, attention should be paid to the state of the musculoskeletal system, the presence of myofascial pain dysfunction. In the study, myofascial dysfunctions were most often detected in the trapezius, suboccipital and masticatory muscles. …”
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Dry eye treatment optimization in patients prior to refractive surgery by S. N. Sakhnov, S. V. Yanchenko, A. V. Malyshev, Z. M. Blyagoz, G. A. Klimenova

“…To evaluate the effectiveness of dry eye syndrome (DES) treatment in patients with meibomian gland dysfunction (MGD) before refractive surgery.Materials and methods. …”
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The role of mitochondria in the ischemic-reperfusion damage of the brain in operations on aortal arch in conditions of experiment by S. M. Gramatiuk, Yu. V. Ivanova, V. I. Kravchenko, O. O. Lohvinenko

“…Due to simultaneous action of these processes the mitochondrial functioning fails so significantly, that becomes one of the key moments in cerebral cellular dysfunction and death. Statistically meaningful difference, taking into account the results, between two groups of investigated animals was not revealed. …”
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THE RISK OF EARLY LIVER ALLOGRAFT DYSFUNCTION IS ASSOCIATED WITH THE TLR-4 GENE GENOTYPE IN THE RS913930 SEQUENCE AND IS IMPLEMENTED VIA HMGB1 NUCLEAR PROTEIN, KUPFFER CELLS AND IL... by A. E. Shcherba, A. M. Kustanovich, A. I. Kireyeva, D. Yu. Efimov, S. V. Korotkov, A. F. Minov, O. A. Lebedz, A. A. Koritko, D. A. Fedoruk, E. O. Santotsky, A. M. Dzyadzko, O. O. Rummo

“…To evaluate the associations of genotypes of clinically relevant nucleotides rs11536865, rs913930 and rs5030717 of the TLR-4 gene with the risk of development and severity of early allograft dysfunction after liver transplantation. Materials and methods. …”
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Content of Some Endothotelium-Dependent Vasoactive Substances in the Blood of Patients, Depending on the Liver Cirrhosis Severity and the Organism’s Redox System State by Abrahamovych M., Abrahamovych O., Fayura O., Tolopko S., Ferko M.

“…It evidences the significant abnormalities in the redox homeostasis of such patients, and subsequently leads to the endothelial dysfunction with impaired metabolism of vasoactive humoral-metabolic substances in the blood of patients. …”
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MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles by Linsey Peters, Leonida Rakateli, Rosanna Huchzermeier, Andrea Bonnin-Marquez, Sanne L Maas, Cheng Lin, Alexander Jans, Yana Geng, Alan Gorter, Marion Gijbels, Sander Rensen, Peter Olinga, Tim Hendrikx, Marcin Krawczyk, Malvina Brisbois, Joachim Jankowski, Kiril Bidzhekov, Christian Weber, Erik AL Biessen, Ronit Shiri-Sverdlov, Tom Houben, Yvonne Döring, Matthias Bartneck, Emiel van der Vorst

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Jiedutongluotiaogan Formula Improves Pancreatic Dysfunction in db/db Mice through Modulating the Gut Microbiota-Short Chain Fatty Acids-NLR Family, Pyrin Domain–Containing Protein... by Jin-Li Luo, Wen-Qi Jin, Li Wang, Qi Zhang, Yu Wang, Cui Wu, Yue Qu, Yu-Ting Peng, Li-Wei Sun, Chun-Li Piao

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Cancer Research Institute, Tomsk National Research Medical Center of the RAS by E. L. Choynzonov, Т. Ya. Kucherova, I. N. Udintseva, Т. V. Serebrov, V. A. Novikov, А. I. Ryabova, P. V. Surkova, O. V. Cheremisina, E. A. Sokolova

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Human Placental Mesenchymal Stem Cells-Exosomes Alleviate Endothelial Barrier Dysfunction via Cytoskeletal Remodeling through hsa-miR-148a-3p/ROCK1 Pathway by Yuzhen Lv, Wenqin Yu, Ruiui Xuan, Yulu Yang, Xiaolan Xue, Xiaowei Ma

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Soluble triggering receptor expressed on myeloid cells 1 (sTREM-1) and polymorphic variants of TREM-1 in the development of multiple organ dysfunction syndrome after coronary ar... by M. V. Khutornya, A. V. Ponasenko, A. V. Tsepokina, A. S. Radivilko, I. I. Zhidkova, A. G. Kutikhin, S. S. Krutitsky, A. S. Golovkin, E. V. Grigoriev

“…To determine the role of TREM-1 gene polymorphism through the changes of sTREM serum levels and their contribution to the development of multiple organ dysfunction syndrome after coronary artery bypass grafting.Materials and Methods. 132 patients with coronary atherosclerosis who had undergone coronary artery bypass grafting were included in the study. …”
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