Neutrophil-to-Lymphocyte Ratio as a Microbiota-Dependent Indicator of Immune Dysfunction and a Long-Term Prognostic Factor in Patients with Cirrhosis by E. K. Tsvetaeva, R. V. Maslennikov, M. S. Zharkova, E. A. Poluektova, G. S. Krasnov, A. V. Kudryavtseva, V. T. Ivashkin

“…Aim: to evaluate the neutrophil-to-lymphocyte ratio (NLR) as a microbiota-dependent indicator of immune dysfunction and a long-term prognostic factor in patients with cirrhosis.Materials and methods. …”
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Different Analysis of β-Cell Dysfunction as Fasting Glucose Progresses in Obese and Nonobese Newly Diagnosed Type 2 Diabetic Patients by Yan Duan, Xiaomeng Sun, Jia Liu, Jing Fu, Guang Wang

“…Materials and Methods. 661 patients with newly diagnosed T2DM were enrolled in the present study. …”
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Triglyceride glucose index is associated with subclinical atherosclerosis and subclinical myocardial dysfunction in patients with newly diagnosed type 2 diabetes mellitus by S. H. Ustabas, E. G. Altunoglu, T. Karabag

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Impact of drug therapy on long-term prognosis in patients with ischemic chronic heart failure with preserved ejection fraction and renal dysfunction by D. A. Lashkul

“…To investigate the effect of modern combined drug therapy for long-term prognosis in patients with ischemic HFpEF and renal dysfunction. Materials and methods. The study involved 243 patients (80.3% men) with ischemic HFpEF with renal dysfunction (age 58.7±9.3 years). …”
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Combination of iLux Photothermal Pulsation Therapy with 0.05% Cyclosporine in the Treatment of Meibomian Gland Dysfunction: A Clinical Study by Xu H, Kang Q

“…Hongliang Xu, Qian Kang Department of Ophthalmology, Aidi Eye Hospital, Chengdu, Sichuan, People’s Republic of ChinaCorrespondence: Qian Kang, Department of Ophthalmology, Aidi Eye Hospital, No. 41.43.45, West Second Section, Second Ring Road, Qingyang District, Chengdu, 610031, Sichuan, People’s Republic of China, Email Xu_hongliang12@163.comObjective: The aim of this study is to investigate the effect of iLux with 0.05% cyclosporine in the treatment of meibomian gland dysfunction.Methods and Materials: In retrospective analysis, 72 patients of meibomian gland dysfunction were selected and divided into combination groups according to different treatment methods (n=32, iLux + 0.05% cyclosporine ophthalmic fluid) and the conventional group (n=44, 0.05% cyclosporine ophthalmic fluid). …”
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Impact of drug therapy on long-term prognosis in patients with ischemic chronic heart failure with reduced ejection fraction and renal dysfunction by D. A. Lashkul

“…To investigate the effect of combined drug therapy for long-term prognosis in patients with ischemic heart failure with reduced ejection fraction of left ventricle and renal dysfunction. Materials and methods. The study involved 140 patients (114 (81.4%) men) with ischemic chronic heart failure; average age was 60 [54.5-68] years. …”
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Association between Portal Hypertensive Gastropathy with Different Grades of Liver Dysfunction in a Tertiary Hospital: A Cross-sectional Study by Pradip Kumar Chowdhury, Kingshuk Kumar Dhar, Gautam Das

“…Background: Controversy exists regarding how and to what extent portal hypertensive gastropathy (PHG) varies with different grades of liver dysfunction. Our aims and objectives were to assess the correlation of PHG with different grades of liver dysfunction. …”
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EFFECT IMBALANCE AQUEOUS BODY FLUIDS, AND RENAL DYSFUNCTION, CARDIOVASCULAR SURVIVAL IN PATIENTS AFTER AN ACUTE CORONARY SYNDROME, MYOCARDIAL REVASCULARIZATION by E. S. Levitskaya, M. M. Batiushin, E. O. Golovinova, V. V. Gul’chenko, A. V. Khripun

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Renal Dysfunction is a Risk Factor of Death after Gastric Endoscopic Submucosal Dissection in Elderly Patients Aged ≥80 Years by Kenichiro Okimoto, Makoto Arai, Hideaki Ishigami, Takashi Taida, Keiko Saito, Daisuke Maruoka, Tomoaki Matsumura, Tomoo Nakagawa, Tatsuro Katsuno, Naoya Kato

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Prevalence of Sexual Dysfunction with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS): An Updated Systematic Review and Meta-Analysis by Saad Alshahrani, Basem A. Fathi, Tamer A. Abouelgreed, Ashraf El-Metwally

“…<i>Background and Objectives</i>: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common condition linked to substantial urogenital symptoms, notably sexual dysfunction. This meta-analysis sought to determine the overall prevalence of sexual dysfunction in men with CP/CPPS, considering the four primary categories: desire, arousal, orgasm, and pain disorders. …”
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A case report of bioprosthetic valve dysfunction after tricuspid valve replacement in a preschool patient: the contribution of pannus and calcification by T. V. Glushkova, E. A. Ovcharenko, A. V. Batranin, K. Yu. Klyshnikov, Yu. A. Kudryavtseva, L. S. Barbarash

“…To assess the contribution of pannus and calcification to the development of bioprosthetic valve dysfunction after tricuspid valve replacement in a pediatric patient.Materials and methods. …”
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Corrigendum to ‘Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction’ [Mater. Today Bio 18 (2023) 100512]... by Zhanqiu Dai, Chen Xia, Tingxiao Zhao, Haoli Wang, Hongsen Tian, Ouyuan Xu, Xunbin Zhu, Jun Zhang, Pengfei Chen

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Total Alkaloids of Rhizoma Corydalis regulates gut microbiota and restores gut immune barrier to ameliorate cognitive dysfunction in diabetic rats by Yazhi Qi, Jun Li, Ya Tang, Rui Cao, Yishu Gao, Qiang Xu, Yusheng Han

“…Background and objectivesGiven the widespread dysbiosis of gut microbiota in patients with T2DM, it has been found that the microbiota-gut-brain axis plays an influential regulatory role in diabetic cognitive dysfunction, and improving gut dysbiosis may be a potential strategy for treating diabetic cognitive dysfunction. …”
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Illustrate the metabolic regulatory effects of Ganoderma Lucidum polysaccharides on cognitive dysfunction in formaldehyde-exposed mouse brain by mass spectrometry imaging by Wen Wang, Yuanyuan Sun, Renting Cao, Wenhui Luo, Shujuan Beng, Jing Zhang, Xiaoqun Wang, Can Peng

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High sensitivity C-reactive protein implicates heterogeneous metabolic phenotypes and severity in metabolic dysfunction associated-steatotic liver disease by Hao Wang, Junzhao Ye, Youpeng Chen, Yanhong Sun, Xiaorong Gong, Hong Deng, Zhiyong Dong, Lishu Xu, Xin Li, Bihui Zhong

“…Abstract Background Whether include high-sensitivity C-reactive protein (Hs-CRP) in diagnostic flow remains debatable during the updated definition to metabolic dysfunction-associated steatotic liver disease (MASLD) despite systemic inflammation contributes to the disease development and progression. …”
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Mitochondrial FIS1 As a Novel Drug Target for the Treatment of Erectile Dysfunction: A Multi-Omic and Epigenomic Association Study by Tianle Zhu, Pan Gao, Yukuai Ma, Peng Yang, Zhi Cao, Jingjing Gao, Junhua Du, Hui Jiang, Xiansheng Zhang

“…Purpose: Mitochondrial dysfunction may impact male erectile function, but the underlying genetic mechanisms remain unclear. …”

Cognitive dysfunction and its associated factors in patients with epilepsy at referral hospitals in the Amhara region: an institutional-based cross-sectional study by Lemlemu Maru, Yibeltal Yismaw Gela, Mihret Getnet, Mihret Getnet, Dagnew Getnet Adugna, Desalegn Anmut Bitew, Ephrem Tesfaye, Hailu Aragie, Awgichew Behaile Teklemariam, Wondwosen Debebe, Mitku Mammo Taderegew, Nega Dagnew Baye, Mihret Melese

“…Therefore, this study aimed to assess cognitive dysfunction and identify factors associated with it in patients with epilepsy who were receiving follow-up care at referral hospitals in the Amhara region.Materials and methodsA multicenter, institutional-based cross-sectional study was conducted among patients with epilepsy who were receiving follow-up care at randomly selected referral hospitals in the Amhara region from January 2024 to July 2024. …”
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Damage to the Cardiovascular System in Patients with SARS-CoV-2 Coronavirus Infection. Part 2: Correction of Myocardial Systolic Dysfunction by V. I. Podzolkov, A. I. Tarzimanova, A. E. Bragina, I. I. Shvedov, E. E. Bykova, A. A. Ivannikov, L. V. Vasilyeva

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Determining the relationship between hormonal background characteristics and signs of female sexual dysfunction in women with and without endometriosis in the prediction of gestati... by L.M. Semeniuk, V.I. Pankiv, Ye.S. Kozachuk, O.I. Kryzhanovska

“…They were divided into 3 groups: group IA (n = 70) — a combination of female sexual dysfunction and extragenital endometriosis, the comparison group IB (n = 30) — female sexual dysfunction without extragenital endometriosis, the control group II (n = 30) — healthy reproductively active women. …”
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PROGNOSTIC VALUE OF ENDOTHELIAL DYSFUNCTION IN CORONARY AND BRACHIAL ARTERIES, AND COMMON RISK FACTORS IN DEVELOPMENT OF CARDIOVASCULAR COMPLICATIONS IN PATIENTS WITH MICROVASCU... by G. N. Soboleva, V. K. Fedulov, A. N. Samko, I. V. Levitsky, A. N. Rogoza, T. V. Balakhonova, Yu. A. Karpov

“…Significant influence on cardiovascular  events occurring in long-term follow-up of MVA  patients,  had  the  risk factors  as  smoking  and  brachial  artery endothelial dysfunction.…”
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