Analysis of complex chromosomal structural variants through optical genome mapping integrated with karyotyping by Xiaoxi Zhu, Huiling Zheng, Xue Wan, Hang Duan, Ying Qi, Weijia Tang, Fan Yang, Fan Yang, Limei Yu, Limei Yu

“…Additionally, the causal relationship between KIF7 gene dysfunction and recurrent miscarriage remains to be experimentally verified in subsequent research.…”
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Assessment of fully digitalized workflow for implant-prosthetic rehabilitation in temporomandibular disorders patients: A clinical study by Giuseppe Minervini, Rocco Franco, Salvatore Crimi, Manuele Basili, Saurabh Chaturvedi, Marco Cicciù, Alberto Bianchi, Gabriele Cervino

“…Digital flow is beneficial ei dysfunctional patients, not about improvements in temporomandibular symptoms but in times of operability and prosthetic retouching.…”
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Lipid metabolites affected by deficient autophagy antagonize the occurrence of autophagy through AMPK signaling in insects by Ling Tian, Qien Zhong, Yubei Yang, Wenmei Wu, Yang Xiao, Sheng Li, Kang Li

“…Abstract Background Autophagy is essential for removing damaged organelles and intracellular materials as well as invasive pathogens. The autophagic degradation of intracellular lipids plays a key role in maintaining cellular homeostasis. …”
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Relation of Follicular Fluid Soluble Receptor for Advanced Glycation End-Products Concentration and Anti Mullerian Hormone in Polycystic Ovary Syndrome and Non-PCOS Women Referring... by Neda Emami, Ashraf Moini, Samira Vesali

“…Background: Reproductive dysfunctions of polycystic ovary syndrome (PCOS) and blood anti-mullerian hormone(AMH) concentration are significantly influenced by the dietary advanced glycation end products (AGEs). …”
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Polyvinyl alcohol improves resistance of epoxy-treated bovine pericardium to calcification in vitro by A. E. Kostyunin, M. A. Rezvova, T. V. Glushkova, D. K. Shishkova, A. G. Kutikhin, T. N. Akentieva, E. A. Ovcharenko

“…Around half of bioprosthetic heart valves become dysfunctional 15 years postimplantation because of structural valve deterioration notable for the degradation and calcification of the prosthetic tissue. …”
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Effect of Jian-Pi-Zhi-Dong Decoction on striatal glutamate and γ-aminobutyric acid levels detected using microdialysis in a rat model of Tourette syndrome by Zhang W, Wei L, Yu W, Cui X, Liu X, Wang Q, Wang S

“…This study evaluated the effect of JPZDD on glutamate (Glu) and γ-aminobutyric acid (GABA) and their receptors in a TS rat model.Materials and methods: Rats were divided into four groups (n=12 each). …”
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Evaluation of Condylar and Airway Volume in Skeletal Class I Patients with Different Vertical Growth Patterns by Fırat Oğuz, Sabahattin Bor, Ayla Khanmohammadi, Melike Kıranşal

“…Cone-beam computed tomography (CBCT) files were analyzed using AI-performed segmentation to ensure accurate measurements. <b>Materials and Methods:</b> A total of 93 individuals with skeletal Class I malocclusion (55 females and 38 males; average age 21.3 ± 3.0 years) were classified into three groups (normodivergent, hyperdivergent, and hypodivergent) according to their vertical growth patterns. …”
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Level of Perceived Stress and Coping Mechanisms among MBBS Students at Government Medical College: A Prospective Observational Study from Delhi by Vikram Singh, Nandini Sharma, Shivani Rao, Priya Arora

“…Conclusions: As exams approached, stress levels increased, particularly among final-year students, who initially used problem-focused strategies but later shifted to dysfunctional coping strategies (distraction, venting, self-blame). …”
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C60 fullerene helps restore muscle soleus contraction dynamics after achillotomy-induced atrophy by Dmytro Nozdrenko, Kateryna Bogutska, Іhor Pampuha, Mykola Petrovsky, Yuriy Prylutskyy

“…Materials and Methods. The biomechanical parameters of muscle soleus contraction of rats were studied by simulating non-functioning hind limbs using a clinical model – a rupture of the Achilles tendon (achillotomy). …”
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Approaches to evaluation of neurocognitive profile in patients with residual schizophrenia depending on a history of cerebral stroke by D. M. Safonov, V. I. Darii, O. M. Stoianov, A. D. Horodokin, K. V. Gapon

“…To assess the structure of neurocognitive dysfunctions in patients with residual schizophrenia with pronounced negative symptoms depending on a history of cerebral stroke. …”
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Electroneuromyography for early diagnosis of diabetic distal polyneuropathy by Elena S. Mazurenko, Lyudmila A. Ruyatkina, Igor A. Pakhomov, Elena V. Chesheva, Larisa O. Gavrilova

“…AIM: To investigate the effectiveness and suitability of electroneuromyography (ENMG) for early DDPN diagnosis. MATERIALS AND METHODS: This study was performed in the Novosibirsk Research Institute of Traumatology and Orthopaedics n.a. …”
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Investigating the Role of the Zinc Finger Protein ZC2HC1C on Autism Spectrum Disorder Susceptibility by Simone Treccarichi, Mirella Vinci, Antonino Musumeci, Rosanna Galati Rando, Carla Papa, Salvatore Saccone, Concetta Federico, Pinella Failla, Martino Ruggieri, Francesco Calì, Agata Polizzi, Andrea Praticò

“…They are involved in a variety of cellular processes, including cell proliferation, differentiation, and apoptosis. <i>Materials and Methods</i>: Whole-exome sequencing (WES) analysis on a patient diagnosed with ASD. …”
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Budding Well: A Fun and Sharing-based Rehabilitation Program through Music and Arts for the Children and Teenagers with Extremity Anomalies by Pak-Cheong Ho, Josephine M-W Wong, Wai-Wang Chau, Alice H-Y Cheung, Hiu-Wun Wong, Gabby S-S Hui, Edwin Lee, Judia S-C Yue, Michael Mak, Wing-Lim Tse

“…The program has run through the third year and a review of the service outcomes has been sorted. Materials and methods: Aged 6–18 years with different kinds and degrees of limb dysfunctions were invited to join the program. …”
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THE CASE OF TRAUMATIC TRANSMISSION CHILD OF HUMAN IMMUNODEFICIENCY VIRUS by Yu. V. Ostankova, A. V. Semenov, M. A. Churina, A. P. Rosolovsky, E. V. Grebyonkina, T. N. Tkachenko, T. А. Zhandarmova, A. А. Totolian

“…Analysis of phylogenetic relationships of HIV  isolates obtained from a child 8 years old and HIV-positive parents to search for a possible source of infection.Materials and  methods. The  blood  plasma  samples of 3 patients (father, mother and child) HIV from Veliky Novgorod were used.  …”
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Chemogenetic tools for modulation of spatial learning in dopamine transporter deficient rats by Arina A. Gromova, Arina A. Gromova, Taisiia S. Shemiakova, Mikhail G. Khotin, Evgeniia N. Petrunina, Anastasia D. Belskaya, Raul R. Gainetdinov, Raul R. Gainetdinov, Natalia P. Kurzina, Anna B. Volnova, Anna B. Volnova

“…Its activity can modulate both norepinephrine and dopamine neurotransmission, particularly in the PFC.Materials and methodsWe used canine adenovirus type 2 (CAV2) to selectively activate LC-NA neurons in DAT-KO rats. …”
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The prognostic significance of BRCA1 gene expression in patients with breast cancer by M. M. Tsyganov, M. K. Ibragimova, A. M. Pevzner, E. Yu. Garbukov, E. M. Slonimskaya, N. V. Litviakov

“…Of particular interest is the assessment of the deficit of homologous recombination, which may include various dysfunctions of the BRCA1 gene. Moreover, it has been shown that a decrease in the functional activity of BRCA1 is reflected in the sensitivity of the tumor to DNA damaging agents, and the prognosis of the disease becomes more favorable.Objective: assessment of the association of BRCA1 gene expression in a breast tumor with the prognosis of the disease.Materials and methods. …”
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Video-urodynamic Profile in Postoperative Cases of Lumbosacral Myelomeningocele with Neurogenic Bladder by Dipanjan Goswami, Gaurav Saxena, Sujoy Neogi, Simmi K Ratan, Prafull Kumar, Chiranjiv Kumar, Md. Fahim Ahmad

“…Conclusion: VUDS is decisive for the therapeutic strategy as it allows the definition of the dysfunctional pattern of the lower urinary tract and detection of risk factors to enable the prevention of major upper urinary tract changes by appropriate treatment. …”
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Long-term restraint stress as a predictor of insulin resistance development in experimental rats by K. B. Romanova, O. V. Hancheva, Yu. M. Kolesnyk

“…The aim of the work was to define the pattern of changes and pathogenetic mechanisms of glycemic curve shape during a glucose tolerance test in rats at 6, 15, and 21 weeks of environmental space restriction. Materials and methods. A total of 55 male Wistar rats aged 6–10 months were used and divided into 4 groups (1 – intact control, 10 rats; 2, 3 and 4 of 15 rats each, which were in conditions of restricted environmental space for 6, 15 and 21 weeks, respectively). …”
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Experience of application of proproceptive modeling of walking in children of early age with motor disorders by A. G. Prityko, N. V. Chebanenko, V. P. Zykov, P. L. Sokolov, E. A. Bukreeva, T. A. Sednenkova, E. Yu. Sergeenko

“…The children had various motor dysfunctions. Children with a predominance of spasticity in the muscles of the lower extremities were 70.6 %, children with a predominance of reduced tone in the muscles of the lower extremities were 29.4 %. …”
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Altered cerebral perfusion in Parkinson's disease patients with anxiety: an arterial spin labeling MRI study by Lu Li, Shiyuan Song, Yingying Hu, Yuan Luo, Lu Wang, Peiyao Zhang

“…CBF values in the left frontal lobe (r = −0.265, P = 0.024), right frontal lobe (r = −0.283, P = 0.015), left temporal lobe (r = −0.287, P = 0.014), and right temporal lobe (r = −0.275, P = 0.019) were negatively correlated with Hamilton Anxiety Scale (HAMA) scores in PD patients.ConclusionThe development of PD-A may be associated with dysfunctional brain perfusion in multiple brain regions, notably the bilateral frontal lobes, temporal lobes, left putamen, and left pallidum. …”
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