FUNCTIONAL POLYMORPHISM OF THE PRO-INFLAMMATORY CYTOKINE GENES IN PULMONARY TUBERCULOSIS by E. G. Churina, O. I. Urazova, V. V. Novitsky, A. V. Sitnikova, S. E. Barmina

“…The MBT antigens can cause dysfunction of the receptors and modulate the cytokine secreting function of immunocompetent cells. …”
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Impact of COVID-19-associated Dysautonomia Phenotypes on the Effectiveness of Venovenous Extracorporeal Membrane Oxygenation by G. E. Savkov, S. S. Petrikov, N. V. Rybalko, L. T. Khamidova, O. Yu. Markatyuk, D. A. Lebedev, K. V. Kiselev, Yu. N. Vrabiy, N. E. Altshuler, K. A. Popugaev

“…A significant increase in respiratory dysfunction was revealed over time in the lShP phenotype. …”
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Low-cost male urogenital simulator for penile implant surgery training: a 3D printing approach by Zixi Wang, Carlo Saija, Nicholas Raison, Abdullatif Aydin, Zhouyang Xu, Katie Zuo, Kawal Rhode, Antonia Pontiki

“…The simulator was produced at a low material cost of £10, with an average production time of 3 h. …”
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Epicardial fat thickness and biomarkers of inflammation in patients with stable coronary artery disease: correlation with the severity of coronary atherosclerosis by O. A. Koshelskaya, T. E. Suslova, I. V. Kologrivova, N. Yu. Margolis, O. A. Zhuravleva, O. A. Kharitonova, E. S. Kravchenko, I. V. Vinnitskaya, R. S. Karpov

“…To study the relationship between the epicardial fat thickness (EFT), biomarkers of inflammation and metabolic dysfunction in patients with coronary artery disease (CAD) and various severity of coronary atherosclerosis.Material and methods. …”
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Incidence and prognostic value of acute kidney injury in pulmonary embolism: data from the SIRENA registry by M. V. Menzorov, V. V. Filimonova, A. D. Erlikh, O. L. Barbarash, S. A. Berns, E. A. Shmidt, D. V. Duplyakov

“…To evaluate the incidence and severity of acute kidney injury (AKI), as well as its ability to reclassify the risk of premature mortality and association with inhospital mortality in patients with pulmonary embolism (PE) in the Russian population.Material and methods. From April 2018 to April 2019, the SIRENA Russian Multicenter Registry included patients with PE, as well as the deceased, in whom the PE was detected by autopsy. …”
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Comparative estimation of the effectiveness of the Khorana, Vienna CATS, and TiC-Onco scores and the vWF/ADAMTS13 ratio in identifying a high risk of thrombotic complications in pa... by A. V. Vorobеv, A. G. Solopova, V. O. Bitsadze, M. M. Baeva, M. E. Sosnyagova, V. N. Galkin, D. O. Utkin, A. D. Makatsariya

“…The Khorana, Vienna CATS, and TiC-Onco scores demonstrate moderate accuracy in predicting thrombosis in cancer patients, partly due to their inability to consider the individual characteristics of endothelial dysfunction and/or overestimation of the impact of “silent” genetic mutations. …”
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Ultrasound changes of internal jugular veins in patients with atrial fibrillation by I. L. Bukhovets, A. S. Maksimova, M. A. Dragunova, K. V. Zavadovsky

“…This can lead to an increase in peripheral resistance in the arterioles, and as a consequence, to impaired cerebral perfusion and cognitive dysfunction.…”
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SENSITIVITY AND SPECIFICITY OF VECTORCARDIOGRAPHY IN DIAGNOSTICS OF ACUTE MYOCARDIAL INFARCTION COMORBID WITH LIVER STEATOSIS AND NON-ALCOHOLIC STEATOHEPATITIS by I. E. Belaya, V. I. Kolomiets

“…In echocardiography it is found that left chambers increase (p<0,001), there is diastolic dysfunction (relaxation disorder of LV — 40%), pseudonormal type — 32%, restrictive type — 28%) with systolic function impairment (p<0,001). …”
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Restoration of Intestinal Propulsion in Patients with Severe Acute Pancreatitis in the Conditions of the Resuscitation and Intensive Care Unit by V. V. Kiselev, S. S. Petrikov, M. S. Zhigalova, S. V. Novikov, N. V. Shavrina, P. A. Yartsev

“…The intestine plays an important role in the processes of systemic inflammation, sepsis and multiple organ dysfunction, in the course of hemorrhagic shock, trauma, burns, pancreatitis, extensive abdominal surgery and in seriously ill patients in intensive care units (ICUs). …”
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New opportunities for preclinical diagnostics of antitumor therapy cardiotoxicity: results of an observational study by Yu. A. Vasyuk, D. A. Vyzhigin, E. Y. Shupenina, E. O. Novosel, E. A. Ulyanova

“…During the observation of oncological patients receiving chemo- and targeted therapy, it was found that a specific pattern, previously not described, was revealed in patients with developed systolic dysfunction upon visual assessment of the longitudinal strain of the LV. …”
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Novel Pt@PCN-Cu-induced cuproptosis amplifies αPD-L1 immunotherapy in pancreatic ductal adenocarcinoma through mitochondrial HK2-mediated PD-L1 upregulation by Pengyu Wang, Weihua Guo, Shuyue Liu, Shouyi Li, Jiaqi Li, Bowen Ding, Fengyi Yin, Yang Yang, Xingjiang Li, Pei Cao, Chaozhe Ma, Wanying Zhang, Yidan Song, Yating Geng, Lantao Liu, Jing Hu, Jihui Hao, Yukuan Feng

“…Methods Pt@PCN-Cu was synthesized via a one-pot method, and its therapeutic potential was assessed in combination with αPD-L1 for the treatment of PDAC. Initially, the material’s properties were characterized, and its efficient cellular uptake was confirmed. …”
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EVALUATION OF THE EFFECTIVENESS OF TREATMENT OF CHRONIC CATARRHAL GINGIVITIS IN CHILDREN WITH DIABETES MELLITUS IN LONG-TERM OBSERVATIONS by L.F. Kaskova, V.A. Honcharenko

“…To evaluate the effectiveness of the proposed treatment method for children with chronical catarrhal gingivitis and diabetes mellitus. Materials and methods. In order to achieve the aim, 50 children with CCG aged 12 years were treated. …”
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Autosomal dominant HK1-related neurodevelopmental disorder with visual defects and brain anomalies (NEDVIBA): An emerging mitochondrial disorder by Bobby G. Ng, Erik A. Eklund, Jill A. Rosenfeld, Abdallah F. Elias, Aya Abu-El-Haija, Celine Bris, Magalie Barth, Jong-Hee Chae, Murim Choi, Holly A. Dubbs, Carl Fratter, Nicola Foulds, Candace Gamble, Ralitza H. Gavrilova, Jaclyn Haven, Trevor L. Hoffman, Jill V. Hunter, Austin Larson, Timothy Edward Lotze, Pilar Magoulas, Emily C. Magness, Debra M. Bootin, Eric D. Marsh, Victoria Nesbitt, Matthew T. Pastore, Joanna Poulton, Shamima Rahman, Fernando Scaglia, Chaya Murali, Jennifer Posey, Joshua Rotenberg, Betsy Schmalz, Deepali N. Shinde, Zöe Powis, Rivka Sukenik-Halevy, Kristen V. Truxal, Tami Uster, Matheus Vernet Machado Bressan Wilke, Erik Klee, Hyewon Woo, Donald Younkin, Jianhua Zhao, Jorge Granadillo, Seema Lalani, David Chitayat, Wendy K. Chung, Hudson H. Freeze, Volkan Okur

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O2- CHARACTERIZATION OF STEATOTIC LIVER DISEASE AND THE ROLE OF GENETIC BACKGROUND IN LATIN AMERICA by LUIS ANTONIO DÍAZ PIGA, Carolina Aguilera, Gustavo Ayares, Francisco Idalsoaga, Mauricio Pizarro, Fernando Javier Barreyro, Sebastián Marciano, Jorge Martínez Morales, Cristiane Villela-Nogueira, Nathalie Leite, Claudia Alves Couto, Rafael Theodoro, Mísia Joyner de Sousa Dias Monteiro, Mario G. Pessoa, Mario Reis Alvares-da-Silva, Fátima Higuera de la Tijera, Adelina Lozano, Pedro Montes, Graciela Castro-Narro, Constanza D. Sabate, Manuel Mendizabal, Francisco Barrera, Daniel Cabrera, Mazen Noureddin, Naim Alkhouri, Winston Dunn, Zobair Younossi, Jeffrey V. Lazarus, Rohit Loomba, Claudia Pinto Marques Souza de Oliveira, Adrian Gadano, Marco Arrese, Juan Pablo Arab

“…Results and Discussion: We included 2,159 patients (93.7% metabolic dysfunction-associated SLD and 6.3% alcohol-associated liver disease) from 13 centers in 5 countries (Argentina, Brazil, Chile, Mexico, and Peru). …”
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Bisphenol B restrains rat leydig cell function via H3K27me3/H3K9me3 histone modifications by Jiayi He, Huiqian Zhang, Hehua Quan, Qingyuan Wang, Congcong Wen, Yiyan Wang, Yang Zhu, Ren-Shan Ge, Xiaoheng Li

“…As an alternative compound of bisphenol A (BPA), bisphenol B (BPB) was widely used in plastic materials. The potential actions of BPB on the function of Leydig cells through the regulation of H3K27me3 and H3K9me3 remains unclear. …”
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Generation of human induced pluripotent stem cell lines derived from two glucose transporter 1 deficiency syndrome patients by Rui Li, Hazuki Tsuboi, Hidenori Ito, Daigo Takagi, Yun-Hsuan Chang, Tomoya Shimizu, Yutaka Arai, Mami Matsuo-Takasaki, Michiya Noguchi, Yukio Nakamura, Kiyoshi Ohnuma, Satoru Takahashi, Yohei Hayashi

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Africa's Backwardness: The Danger Of Abusive Reference To Neo-colonialism by Wafaa Taleb

“…These countries remain reservoirs of cheap labor and raw materials, while restricting access to advanced production techniques to develop their own economies. …”
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Protocol for the development of Polish clinical guidelines for the management of patients with systemic lupus erythematosus by Joanna Makowska, Brygida Kwiatkowska, Magdalena Krajewska-Włodarczyk, Bogdan Batko, Marcin Stajszczyk, Jerzy Świerkot, Zbigniew Żuber, Piotr Leszczyński, Agata Sebastian, Magdalena Władysiuk, Irena Walecka, Michał Chmielewski, Mariusz Stasiołek, Maria Maślińska

“…Left untreated or inadequately managed, SLE can lead to severe organ dysfunction, disability, and reduced quality of life. …”
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CLINICAL AND LABORATORY CHARACTERISTICS OF PATIENTS WITH ISCHEMIC HEART DISEASE RESISTANT TO ACETYLSALICYLIC ACID IN PERIOPERATIVE PERIOD OF CORONARY ARTERY BYPASS GRAFT: RESULTS O... by Yu. I. Grinshtein, A. A. Kosinova, I. Yu. Grinshtein, A. V. Kovalev, V. G. Sukhovol'skiy, A. A. Savchenko

“…Cardiopulmonary bypass, COX-2 inhibitors, renal dysfunction, the inflammatory response, may be possible reasons of the ASA-resistance after CABG. …”
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Trends in intestinal aging: From underlying mechanisms to therapeutic strategies by Yajun Wang, Xueni Zhang, Mengli Qing, Wen Dang, Xuemei Bai, Yingjie Wang, Di Zhou, Lingjuan Zhu, Degang Qing, Juan Zhang, Gang Chen, Ning Li

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