Peculiarities of cardiovascular remodeling in hypertensive patients at high additional risk with concomitant subclinical hypothyroidism by V. V. Syvolap, Ye. V. Novikov

“…Therefore, there is a need to study the influence of subclinical hypothyroidism on the cardiovascular remodeling peculiarities in patients with arterial hypertension (AH). Material and methods. The study involved 124 patients with AH stage II divided into two groups. …”
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Enhanced risk stratification scale for predicting death and non-fatal cardiovascular events in patients of the PROGNOZ IBS registry by S. N. Tolpygina, S. Yu. Martsevich, A. D. Deev

“…To develop a risk stratification scale for predicting cardiovascular events (CVEs) in patients with chronic coronary artery disease (CAD) based on the data from the PROGNOZ IBS registry.Material and methods. The PROGNOZ IBS registry included 641 patients (men, 500; women, 141) living in Moscow and the Moscow Region, who were routinely admitted to the National Medical Research Center for Therapy and Preventive Medicine from January 1, 2004 to December 31, 2007 with a preliminary diagnosis of CAD. …”
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Differentiating Maternal Angiogenesis Factors between Early and Late Onset Preeclampsia: Higher sflt-1 in Early Onset Preeclampsia, Lower PlGF and Higher sflt-1/PlGF Ratio in Late... by Joserizal Serudji, vaulinne Basyir, Tara Fadhillah

“…Background: Early onset preeclampsia (PE) is considered a fetal disorder that is associated with placental dysfunction. While late onset preeclampsia is considered a maternal disorder that associated with a normal placenta. …”
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Strain-specific effects of Akkermansia muciniphila on the regulation of intestinal barrier by Yang Liu, Qing Liu, Chengcheng Zhang, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai

“…This study confirmed the different effects of A. muciniphila strains on gut barrier modulation and provided molecular and genetic targets for the screening of A. muciniphila strains with superior protection against gut barrier dysfunction.…”
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The Hormonal dysregulation and its consequences in Obese Women - overview by Katarzyna Maria Pala, Wiktoria Tomaszewska, Paweł Siudziński, Mateusz Łyko, Alicja Skoczylas, Maria Golińska, Anna Nowak, Jakub Kurasz, Wiktoria Podlasiewicz, Piotr Dudziak, Wojciech Maj

“…Mechanisms like insulin resistance, hyperandrogenism, and leptin dysfunction are central to these effects.   Conclusion   A multidimensional treatment approach, including lifestyle changes, pharmacotherapy (e.g., GLP-1 agonists), and surgical interventions, is essential. …”
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Multifunctional hydrogel targeting senescence to accelerate diabetic wound healing through promoting angiogenesis by Hao Yang, Yongfei Chen, Yanchao Rong, Yuxi Zhou, Shuting Li, Xiaohui Li, Honglin Wu, Dongming Lv, Xiaoling Cao, Peng Wang, Jiayuan Zhu, Bing Tang, Zhicheng Hu

“…The synergistic effects of PNS and IGF-1 within the hydrogel established a pro-regenerative microenvironment to address both pathological ageing and vascular dysfunction. These findings highlight GelMA/PNS/Alg@IGF-1 as a promising therapeutic platform for diabetic wound management, as this material offers dual anti-senescence and proangiogenic efficacy to overcome the complexities of chronic wound healing. …”
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Kinesio Taping versus Oromotor Therapy of Drooling in Down Syndrome: A Quasi-experimental Study by Radlia Azizah Yunus, Nilla Mayasari, Sylvia Evelyn Aritonang, Waode Nikmatiah, Wan Najwa Zohdi, Mohd Syazmin Sharial

“…Drooling is a prevalent issue for individuals with Down syndrome due to oral motor dysfunction and worsening other health complications. …”
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Texture analysis as a marker for identifying joint changes in temporomandibular disorders on magnetic resonance imaging by Victória Geisa Brito de Oliveira, Elaine Cristina de Carvalho Beda Correa de Araujo, André Luiz Ferreira Costa, Michelle Bianchi de Moraes, Sérgio Lucio Pereira de Castro Lopes

“…KEYWORDS Dentistry; Diagnostic imaging; Magnetic resonance imaging; Radiomics; Temporomandibular joint dysfunction syndrome …”
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Encoding-related hippocampus connectivity for scenes, faces, and words: Healthy people compared to people with temporal and frontal lobe epilepsy by Anna Doll, Daniel A. Schlueter, Martin Wegrzyn, Friedrich G. Woermann, Kirsten Labudda, Christian G. Bien, Johanna Kissler

“…Together, these findings further delineate the network architecture of memory in healthy people and its dysfunction in focal epilepsies, which prospectively could inform surgical interventions.…”
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Adaptive Phage Therapy in the Treatment of Patients with Recurrent Pneumonia (Pilot Study) by N. V. Beloborodova, A. V. Grechko, M. M. Gurkova, A. Yu. Zurabov, F. M. Zurabov, A. N. Kuzovlev, A. Yu. Megley, M. V. Petrova, V. M. Popova, I. V. Redkin, N. I. Sergeyev, E. A. Chernevskaya, M. Yu. Yuriev, A. A. Yakovlev

“…To evaluate the safety and efficacy of the adaptive phage therapy technique in patients with recurrent pneumonia in neurological critical care.Material and methods. The clinical study included 83 chronically critically ill patients with severe brain damage. …”
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End-stage renal disease after renal cancer surgery: risk factors and overall survival by John Åkerlund, Börje Ljungberg, Sven Lundstam, Ralph Peeker, Erik Holmberg, Marianne Månsson, Anna Grenabo Bergdahl

“…Efforts to spare renal function, including nephron-sparing surgery and active surveillance in appropriate cases, are highly relevant to reduce the development of severe kidney dysfunction. …”
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Patterns of germline and somatic mutations in 16 genes associated with mismatch repair function or containing tandem repeat sequences by Shih‐Ching Chang, Yuan‐Tzu Lan, Pei‐Ching Lin, Shung‐Haur Yang, Chien‐Hsing Lin, Wen‐Yi Liang, Wei‐Shone Chen, Jeng‐Kai Jiang, Jen‐Kou Lin

“…The somatic mutation burden might result from not only the affected genes in germline mutations but also through the dysfunction of downstream effectors. The AXIN2 gene might associate with hypermutation in tumors. …”
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Cardiopulmonary factors associated with atrial fibrillation in patients with chronic obstructive pulmonary disease by E. I. Leonova, G. G. Shechyan, V. S. Zadionchenko, T. V. Adasheva, A. D. Deev, I. V. Fedorova

“…To study the relationships between clinical and functional features of chronic obstructive pulmonary disease (COPD) and status of cardiovascular system with focus on identifying factors associated with the atrial fibrillation (AF) in patients with COPD.Material and methods. Patients (n=94) with COPD out of exacerbation and airways obstruction of 2-4 degree (GOLD 2013) were examined. …”
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Functional outcomes after retrosigmoid approach to the cerebellopontine angle: Observations from a single-center experience of over 13 years by Amir Kaywan Aftahy, Maria Goldberg, Vicki M. Butenschoen, Arthur Wagner, Bernhard Meyer, Chiara Negwer

“…Research question: To analyze surgical outcome of RSA. Material and methods: This study involved a retrospective review of patient charts from a single center, focusing on the surgical procedure and outcomes following the operation. …”
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Rare filamin C variants among patients with hypertrophic cardiomyopathy referred for septal myectomy by S. E. Andreeva, A. V. Gurshchenkov, V. V. Zajcev, A. A. Kozyreva, A. I. Mihaleva, A. S. Murav'ev, V. K. Grebennik, L. B. Mitrofanova, M. L. Gordeev, O. M. Moiseeva, A. A. Kostareva

“…One patient with p.His1834Tyr FLNC variant had reverse curve interventricular septum morphology, whereas other patients had predominant hypertrophy of basal segment of interventricular septum. Diastolic dysfunction did not exceed grade 1-2 in all four patients.Conclusion. …”
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Cardiopulmonary factors associated with atrial fibrillation in patients with chronic obstructive pulmonary disease by E. I. Leonova, G. G. Shechyan, V. S. Zadionchenko, T. V. Adasheva, A. D. Deev, I. V. Fedorova

“…To study the relationships between clinical and functional features of chronic obstructive pulmonary disease (COPD) and status of cardiovascular system with focus on identifying factors associated with the atrial fibrillation (AF) in patients with COPD.Material and methods. Patients (n=94) with COPD out of exacerbation and airways obstruction of 2-4 degree (GOLD 2013) were examined. …”
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The Choice of Treatment Tactics in Patients with Severe Acute Pancreatitis Taking Into Account the Factor of Intra-Abdominal Hypertension by B. M. Belik, G. M. Chirkinyan, R. S. Tenchurin, Z. A. Abduragimov, D. V. Mareyev, A. R. Dadayan, M. A. Oskanyan, A. R. Sapraliyev

“…To assess the role and clinical significance of IAP monitoring in patients with severe AP with various manifestations of organ dysfunction and, offer a set of therapeutic measures aimed at resolving intra-abdominal hypertension.Material and methods. …”
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Tear substitution therapy optimization of dry eye syndrome and cataract patients by S. N. Sakhnov, S. V. Yanchenko, A. V. Malyshev, A. R. Ceeva, L. M. Petrosyan, O. A. Baskakov, G. L. Kolomiec

“…Group 1 included 30 mild DES patients with lipid deficiency who had a negative lipid interference test, meibomian gland dysfunction (MGD), and aqua deficiency absence (Schirmer-1 test > 15 mm). …”
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The role of urodynamic study in pudendal nerve entrapment syndrome by C. Fernandes, V. Viegas, A. Artiles Medina, J. Morale Herrea, J. Casado, L. Vega, C. Luque, L. San José, L. López-Fando Lavalle

“…A statistically significant difference was found between gender and UDS dysfunction (p=0.013), with underactive detrusor predominance in women (44%) and bladder outlet obstruction in men (40%). …”
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CARDIOVASCULAR HEMODYNAMICS AND SPECIFICS OF 24-HOUR BP PROFILE IN PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY AND INADEQUATE BP REACTION ON PHYSICAL EXERTION by F. M. Khashieva, A. E. Demkina, N. S. Krylova, E. A. Kovalevskaya, N. G. Poteshkina

“…To study structural and functional parameters of the heart, vessels and24-hour blood pressure parameters in patients with HCMP and IRBP in physicalexertion.Material and methods. 17 patients with HCMP (13 women, meanage54,0±11,4y.)underwent echocardiography (EchoCG), ambulatory blood pressure monitoring(ABPM) with assessment of vessels rigidity, exercise test on treadmill. …”
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