Small Extracellular Vesicles Derived From Damaged Muscle Aggravate Kidney Injury Progression by Songling Jiang, Seunghee Kang, Oran Kwon, Wonhyo Seo, Eun‐Jung Jin, Hunjoo Ha, Joo Young Huh

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Clinical course, neurohumoral and hemodynamic disorders in patients with stable angina pectoris on the background of community-acquired pneumonia by N. S. Mykhailovska, T. O. Kulynych, G. V. Grytsay

“…Objective: to study the clinical course, neurohumoral and hemodynamic changes in patients with coronary heart disease after community acquired pneumonia. Materials and methods: 51 patients with coronary heart disease: stable angina pectoris, 2-3 functional class (22 men and 29 women), from 52 to 78 years old. …”
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Roles of extracellular vesicles derived from immune cells in atherosclerosis by Kai Qiao, Xinyue Cui, Jiamin Gao, Fengyi Yu, Haohao Liu, Yichen Dai, Jiming Liu, Yu Yang, Xunde Xian, Jinming Hu, Junnan Tang, Xiaolin Cui

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Antithrombotic Activity of an Indolinone Derivative – a Soluble Guanylate Cyclase Stimulator by V. V. Bykov, A. V. Bykova, V. I. Smolyakova, G. A. Chernysheva, O. I. Alyev, A. M. Anishenko, A. V. Sidekhmenova, S. A. Stankevich, V. A. Khazanov, A. I. Vengerovsky

“…Antithrombotic action of GRS compound results not only from its antiplatelet action, but also from the alleviation of endothelial dysfunction in arteries and veins.…”
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SYNTHESIS, ANTIAGGREGATION AND ANTITROMBOTIC ACTIVITIES OF NEW DERIVATIVES OF HYDROXYBENZOIC ACIDS WITH TAURIC FRAGMENT by A. K. Brel, N. V. Atapina, Yu. N. Budaeva, S. V. Lisina, S. S. Tsaruk, D. V. Kurkin, I. N. Tyurenkov

“…An analysis of modern scientific literature revealed the protective effect of taurine in diabetes mellitus and cardiovascular diseases, liver dysfunction, gastrointestinal tract, and kidney diseases.The aim of the article is to study synthesis of new compounds, determination of their physical characteristics and assessment of their antiplatelet and antithrombotic activities in vitro and in vivo.Materials and methods. …”
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Oxidative damage to lipids improves with Omega-5 fatty acid supplementation treatment in patients with severe alcoholic hepatitis by Moisés Martínez-Castillo, Jacqueline Cordova-Gallardo, Abigail Hernandez-Barragan, Marisela Hernández-Santillán, Diana Mungía-Ramos, Froylan Martínez-Sánchez, Daniel Santana-Vargas, Gabriela Gutiérrez-Reyes

“…Inflammation and redox imbalance play a crucial role in promoting the dysfunction of hepatocytes and reducing patient survival. …”
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Clinical portrait of a patient with acute coronary syndrome and type 2 diabetes mellitus: a novel strategy for the diagnosis, prognosis and treatment by M.I. Shved, I.O. Yastremska, L.V. Levytska, V.Yu. Kuchmiy, O.A. Prokopovych, Ya.M. Kitsak, R.M. Liakhovych

“…The purpose of the study: to determine the impact of type 2 diabetes on the severity of clinical course, changes in laboratory and instrumental findings, the prognosis and treatment strategy selection in patients with acute coronary syndrome (ACS). Materials and methods. We have examined 75 patients with ACS, which has developed on the background of T2DM (the main group), and 28 patients with ACS without T2DM (the control group). …”
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IMPACT OF MULTIPLE MYELOMA: REVEALING CLINICAL AND GENETIC ASPECTS by VC Pereira, AM Cavalcante, CBMM Neto, DRR Firmino, IO Córdoba, LA Coelho, LB Cerreti, SZ Jorge, VCC Oliveira, G Suhett

“…Objective: This study addresses the impact of multiple myeloma (MM), focusing on essential clinical and genetic aspects to understand its pathogenesis and impact on public health. Materials and methods: This study critically reviewed current guidelines on diagnosis, risk stratification, and treatment of multiple myeloma (MM). …”
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Correlation between headache, cervical pain, and bruxism: retrospective study on TMD patients by Raúl E. Frugone-Zambra, Gianfranco Battaglia-Ardito, Andrea Berzaghi, A Joaquín Poblete-Gutiérrez, Carmen Luz Gonzalez-Poblete, Antonio Jiménez-Silva, Cristóbal Frugone-Zaror, Verónica Bittner-Schmidt, Sergio Bortolini

“…Symptoms commonly include pain and dysfunction of the masticatory muscles, temporomandibular joints (tmj), and joint noises. …”
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Analysing the role of ultraviolet A1 phototherapy in the treatment of primary cutaneous lichen amyloidosis in a patient with skin phototype 1 by Sam Hughes, Rossel Ahmad, Maryam Kakar, Novakovic Ljubomir, John Ferguson

“…Here, we report a case of LA in a 72-year-old British man with Fitzpatrick skin type 1, highlighting an atypical distribution and sustained resolution of pruritus following UVA1 phototherapy. Materials and Methods: A 72-year-old British man with Fitzpatrick skin type 1 presented with a 2-year history of severely pruritic papules involving the calves, buttocks and intergluteal fold. …”
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Retinal Microvascular Profile of Patients with Coronary Artery Disease by Alexandra Cristina Rusu, Raluca Ozana Chistol, Grigore Tinica, Cristina Furnica, Simona Irina Damian, Sofia Mihaela David, Klara Brînzaniuc, Karin Ursula Horvath

“…In this study, we aimed to evaluate the association of retinal microvascular features with myocardial dysfunction and CVD risk factors in a group of patients with significant coronary artery disease (CAD) compared to patients with newly diagnosed isolated arterial hypertension and healthy controls. …”
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Functional state of cardiomyocyte mitochondria in malignant process in presence of comorbid pathology in experiment by E. M. Frantsiyants, I. V. Neskubina, N. D. Cheryarina, E. I. Surikova, A. I. Shikhlyarova, V. A. Bandovkina, L. A. Nemashkalova, I. V. Kaplieva, L. K. Trepitaki, P. S. Kachesova, I. M. Kotieva, M. I. Morozova, Yu. A. Pogorelova

“…An analysis of indices of free radical oxidation and respiration of mitochondria of heart cells in a malignant process in presence of diabetes mellitus and chronic neurogenic pain in experimental animals.Materials and methods. The study included outbred female rats (n=32) and С57ВL/6 female mice (n=84). …”
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Prognostic significance of laboratory parameters in assessment the severity of the course and outcome of coronavirus disease (COVID-19) by N. V. Dryagina, N. A. Lesteva, A. A. Denisova, E. A. Kondratyeva, M. Yu. Shabunina, A. N. Kondratyev

“…At the time of admission, patients with an unfavorable outcome already have initial manifestations of organ dysfunction (assessed by creatinine, urea, and troponin levels). …”
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Combined effects of aerobic exercise with ketogenic mediterranean and hypocaloric balanced diets on adolescents with polycystic ovarian syndrome by Reham Hamoda, Nada Elkady, Afaf Botla, Amir Gabr, Efrem Kentiba, Shaimaa Hamed

“…While both diets paired with exercise improved metabolic and anthropometric parameters over time, ketogenic Mediterranean Diet’s anti-inflammatory properties and metabolic flexibility likely synergize with aerobic training to target polycystic ovarian syndrome specific endocrine dysfunction. These findings advocate for personalized dietary strategies alongside structured exercise in adolescent polycystic ovarian syndrome management.…”
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Expert perspectives on the use of safinamide for Parkinson’s disease in Portugal: insights from a Portuguese Delphi Consensus by Ana Margarida Rodrigues, Cristina Costa, Miguel Gago, Miguel Grunho, Leonor Correia Guedes, Ana Morgadinho, Maria Jose Rosas, Rita Simoes, Ana Graca Velon

“…However, no consensus was achieved regarding safinamide’s efficacy in managing orthostatic hypotension, cognitive issues, urinary and sexual dysfunction, as well as its safety profile in PD patients with hallucinations. …”

Psycho-emotional well-being and sexual function of patients with borderline ovarian tumors by A. Yu. Vlasina, A. G. Solopova, E. A. Son, A. E. Ivanov, I. M. Zhalyalova

“…After 12 months of comprehensive rehabilitation, sexual function was almost completely recovered in Group I (22.5 ± 5.4 score), whereas in Group II sexual dysfunction was markedly evident (14.9 ± 6.4 score).Conclusion. …”
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Robot-assisted laparoscopic ureteropelvic junction plasty in children using the da Vinci Xi robotic system: a Russian first experience by V. V. Sizonov, A. G. Makarov, S. M. Pakus, D. G. Kvaratskhelia, E. V. Orlova, S. G. Piskunova, M. I. Kogan

“…Postoperatively, only one patient experienced stent dysfunction, which was successfully managed without the need for stent replacement.Conclusions. …”
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Single-center experience in kidney transplantation: outcomes, conclusions, and perspectives by M. Sh. Khubutia, I. V. Dmitriev, A. G. Balkarov, Yu. A. Anisimov, N. V. Shmarina, N. V. Zagorodnikova, N. V. Borovkova, M. G. Minina, D. V. Lonshakov, V. O. Aleksandrova, V. Smirnova, A. U. Rustambek

“…This paper examines the outcomes of KT performed between 2019 and 2023.Materials and methods. There were 1,106 KTs deceased donor KTs performed between January 1, 2029, and December 31, 2023. …”
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Clinical manifestations, and oxidative stress imbalance in children with obesity and MASLD by Isabel Villagómez-López, Laura Mejía-Pérez, Moisés Martínez-Castillo, Liliana Suárez-Bonilla, Daniel Santana-Vargas, Zaira Medina-Avila, Abigail Hernandez-Barragan, Jessica Limon-Castillo, Dana Mercado-Herrera, Gabriela Gutierrez-Reyes

“…Introduction and Objectives: Metabolic dysfunction-associated steatotic liver disease (MASLD) is often considered a multifactorial disease that has shown high incidence in recent years in both children and adults. …”
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Effect of NT-proBNP on Serum Calcium: A Longitudinal Analysis by Maria Rita Stancanelli, Giuseppe Restivo, Thea Corriere, Carmela Cannarozzo, Maria Gabriella Ferrara, Rosario Salemi, Maria Eva Sberna, Angelo Iraci, Ada Restivo, Valeria Furia, Elisa Longhitano, Domenico Santoro, Vincenzo Calabrese

“…<i>Conclusions</i>: This is the first study to evaluate the longitudinal impact of NT-proBNP on serum calcium, highlighting a potential clinical relevance in patients with cardiac dysfunction. Limitations include a retrospective design and a lack of urine calcium data. …”
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