Patient-reported outcomes between proton and photon therapy in nasopharyngeal carcinoma patients: A longitudinal cohort study by Ching-Nung Wu, Yu-Ming Wang, Wei-Chih Chen, Yun-Hsuan Lin, Shau-Hsuan Li, Chung-Feng Hwang, Bing-Shen Huang, Chung-Ying Lin, Sheng-Dean Luo

“…Background and purpose: This study aimed to compare patient-reported outcomes (PROs) between intensity-modulated proton therapy (IMPT) and volumetric-modulated arc therapy (VMAT) in treating nasopharyngeal carcinoma (NPC). Materials and methods: A prospective cohort study was conducted at a tertiary care center from 2021 to 2023. …”
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Pharmacogenetic aspects of the effectiveness of nonsteroidal anti-inflammatory drugs and opioids for postoperative pain management in patients after total joint arthroplasty by A. S. Zhiryakova, N. P. Denisenko, S. N. Tuchkova, A. S. Petrukhina, A. V. Kryukov, I. V. Sychev, K. B. Mirzaev, O. V. Averkov, V. I. Vechorko, E. O. Filatov, D. A. Sychev

“…Objective: to study the possible relationship between genetic, clinical, laboratory, demographic data and the average level of pain postoperatively, the need for opioid analgesics in patients who underwent total knee or hip arthroplasty.Materials and methods. The study included 61 patients who underwent total knee or hip arthroplasty. …”
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Large vessel vasculitis evaluation by CTA: impact of deep-learning reconstruction and “dark blood” technique by Ning Ding, Xi-Ao Yang, Min Xu, Yun Wang, Zhengyu Jin, Yining Wang, Huadan Xue, Lingyan Kong, Zhiwei Wang, Daming Zhang

“…Abstract Objectives To assess the performance of the “dark blood” (DB) technique, deep-learning reconstruction (DLR), and their combination on aortic images for large-vessel vasculitis (LVV) patients. Materials and methods Fifty patients diagnosed with LVV scheduled for aortic computed tomography angiography (CTA) were prospectively recruited in a single center. …”
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Repeatability and prognostic value of radiomic features: a study in esophageal cancer and nasopharyngeal carcinoma by Jie Gong, Fan Meng, Changhao Liu, Jianchao Lu, Jie Li, Zhi Yang, Hongfei Sun, Xinzhi Teng, Jiang Zhang, Jing Cai, Mei Shi, Lina Zhao

“…Abstract Objectives To investigate whether radiomic features (RFs) repeatability and their prognostic value are study-specific. Materials and methods This retrospective study included 234 esophageal cancer (EC) patients (contrast-enhanced computed tomography (CECT) and fluorine-18 fluorodeoxyglucose positron emission tomography (PET)), and 525 nasopharyngeal carcinoma (NPC) patients (CECT). …”
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Implementation strategies: lessons learned during an e-learning intervention to improve dietary behaviors and feeding practices in early childhood education and care by Henrik Lian, Nina Cecilie Øverby, Frøydis Nordgård Vik, Anine Christine Medin, Natalie Garzon Osorio, Christine Helle, Tormod Bjørkkjær, Penelope Love, Harry Rutter, Mary Elizabeth Barker, Elisabet Rudjord Hillesund, Sissel Heidi Helland

“…This study explores ECEC staff views and experiences with selected strategies for implementing an e-learning resource in ECEC centers in a municipality in Southern Norway. Methods The study is a part of the Nutrition Now study, a hybrid type 1 non-randomized controlled trial. …”
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Augmentation of bone formation by sympathectomy in rats as evaluated by [99mTc]Tc-MDP by Zili Cai, Zili Cai, Xiuting Lin, Xiuting Lin, Yuehong Zhuang, Yuehong Zhuang, Yuehong Zhuang, Weibing Miao, Weibing Miao, Yun Xie, Yun Xie

“…Given that 99mTc-methylene diphosphonate ([99mTc]Tc-MDP) uptake reflects active bone formation and mineralization, this study aims to investigate the effects of sympathetic denervation on bone formation in rats using [99mTc]Tc-MDP SPECT/CT imaging.Materials and methodsTwenty rats were randomly assigned to a superior cervical ganglionectomy (SCGx) group (n = 10) or a sham-operated control group (n = 10). …”
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Bone Reporting and Data System on MRI (Bone-RADS-MRI): a validation study by four readers on 275 cases from three local and two public databases by Yue Xing, Yangfan Hu, Xianwei Liu, Defang Ding, Shun Dai, Liangjing Lyu, Guangcheng Zhang, Shiqi Mao, Qian Yin, Junjie Lu, Jiarui Yang, Yang Song, Huan Zhang, Chengzhou Li, Weiwu Yao, Jingyu Zhong

“…Abstract Objective To evaluate the reproducibility and effectiveness of the Bone Reporting and Data System on MRI (Bone‐RADS-MRI) for incidental solitary bone lesions in adults. Materials and methods We retrospectively included 275 MRI cases from three local and two public databases, respectively. …”
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Dynamic Monitoring of CD200 Mediated by Ascites-Derived Exosomes as a Predictor of Survival and Response to Front-Line Chemotherapeutics in Advanced High-Grade Serous Ovarian Cance... by Ying Ji, Shanshan Liu, Genju Wang, Xin Chen, Yujuan Li, Xiaogai Zhi, Hongxiu Jiang, Juan Tang, Yi Ding, Shuli Zhao, Hongmei Zhou, Aiwei Xiong

“…However, the potential of CD200 to serve as a predictor of ovarian cancers remains unexplored. Methods: We performed dynamic measurements of exosome-mediated or serum CD200 levels at primary diagnosis, post-operation, and three cycles after chemotherapy. …”
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Prediction of the efficacy of neoadjuvant chemoradiotherapy in patients with rectal cancer based on a texture analysis of T2-weighted magnetic resonance tumor image obtained at pri... by Yana A. Dayneko, Tatiana P. Berezovskaya, Oleg A. Mirzeabasov, Sergey O. Starkov, Sofiya A. Myalina, Aleksey A. Nevolskikh, Sergey А. Ivanov, Andrey D. Kaprin

“…AIM: To assess the texture characteristics of locally advanced rectal cancer in primary T2-weighted imaging (T2-WI) as a potential predictor for the efficacy of standard neoadjuvant chemoradiotherapy and develop a prediction system for the efficacy of neoadjuvant chemoradiotherapy based on them. MATERIALS AND METHODS: The retrospective study enrolled 82 patients with locally advanced rectal cancer who received combination treatment with neoadjuvant chemoradiotherapy. …”
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Risk factors of adverse outcome of COVID-19 and experience of Tocilizumab administration in patients on maintenance hemodialysis due to diabetic kidney disease by E. M. Zeltyn-Abramov, M. A. Lysenko, N. F. Frolova, T. N. Markova, N. I. Belavina, N. N. Klochkova, S. V. Kondrashkina, R. T. Iskhakov, A. I. Ushakova

“…Data about peculiarity of clinical course and Tocilizumab (TCZ) administration in patients with T2DM receiving MHD due to outcome of diabetic kidney disease (DKD) are not yet highlighted in current publications.AIMS: Identification of risk factors (RF) of adverse COVID-19 outcome and evaluation of TCZ administration in patients with T2DM receiving MHD due to DKD.MATERIALS AND METHODS: The patients treated in Moscow City Hospital No52 were included in retrospective observational study. …”
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Longitudinal Changes in Corneal Thickness over 8 Years: Findings from the National Institute for Longevity Sciences–Longitudinal Study of Aging Population-Based Cohort Study in Jap... by Hideki Fukuoka, MD, PhD, Chikako Tange, PhD, Fujiko Ando, MD, PhD, Hiroshi Shimokata, MD, PhD, Yukiko Nishita, PhD, Rei Otsuka, PhD

“…We excluded participants with corneal pathologies, contact lens use, glaucoma medication, or missing endothelial cell density measurements. Methods: Central corneal thickness was measured using calibrated specular microscopy (SP-2000; Topcon Corporation) at 2 time points approximately 8 years apart. …”
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The first experience of using upadacitinib in the treatment of rheumatoid arthritis in real clinical practice (results of the multicenter project “RACURS”) by V. N. Amirjanova, A. E. Karateev, E. Y. Pogozheva, A. A. Baranov, V. I. Mazurov, R. R. Samigullina, O. N. Anoshenkova, N. A. Lapkina, T. Yu. Grineva, E. L. Nasonov, A. M. Lila

“…Despite the availability of convincing data from international randomized clinical trials, there is insufficient information about the efficacy and safety profile of UPA, the quality of life of patients receiving the drug in real clinical practice.Aim of the study – to assess the efficacy and tolerability of the UPA drug at a dose of 15 mg/day in patients with rheumatoid arthritis with moderate and high disease activity and to assess their quality of life in real clinical practice.Materials and methods. The study included 41 patients with RA with insufficient effect of previous therapy with DMARDs or GEBDs, persisting moderate or high disease activity, who were initiated with UPA therapy in 7 rheumatological centers of the Russian Federation. …”
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Evidence for the use of a nonsteroidal mineralocorticoid receptor antagonist for the treatment of chronic kidney disease by Mariana Morais David Pliças, Bernardo Marques da Silva, Edgar Avito Fernandes de Almeida

“…This work summarizes the evidence on the use of non-steroidal mineralocorticoid receptor antagonists on chronic kidney disease. Materials and methods: A search was performed on PubMed and ClinicalTrials.gov using relevant keywords for clinical trials and observational studies, finished or ongoing, from 2019 to 2023. …”
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Age-related features of the pattern of lymphocyte subpopulations and functional activity of peripheral blood mononuclear cells in patients with chronic kidney disease before and af... by D. V. Artemov, A. B. Zulkarnaev, A. V. Vatazin

“…Objective: to analyze the features of the pattern of lymphocyte subpopulations and the functional activity of peripheral blood mononuclear cells in older adult patients with chronic kidney disease. Materials and methods. The study featured 21 patients with chronic kidney disease (CKD), over 55 years of age, who underwent kidney transplantation (KT) from unrelated suboptimal donors. …”
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Dynamic Migration Pattern of Groundwater and Deformation Mechanism in Cataclastic Bedding Rock Landslides: A Case Study of Muyubao Landslide in Three Gorges Reservoir Area by DENG Mao-lin, LIANG Zhi-kang, WANG Guo-fa, WANG Biao, ZHOU Lu-lu, WAN Hang, PENG Xu, SU Peng-min, ZHU Xiao-han

“…This paper attempts to establish an interaction model linking rainfall, reservoir water, and groundwater with groundwater as the main triggering factor of landslide deformation, and to further reveal the dynamic migration patterns of groundwater under the coupled effects of reservoir water level fluctuations and rainfall. [Methods] The study took the Muyubao Landslide, a cataclastic bedding landslide in the Three Gorges Reservoir area, as a case study. …”
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Photon-counting CT in maxillofacial and temporal bone CT—a comparative analysis of image quality and dose with high-end energy-integrating CT systems by Yannik Christian Layer, Narine Mesropyan, Alexander Isaak, Dmitrij Kravchenko, Leon Bischoff, Claus C. Pieper, Patrick Kupczyk, Julian A. Luetkens, Benjamin P. Ernst, Daniel Kuetting

“…Abstract Background This experimental study aimed to compare the image quality of maxillofacial and temporal bone imaging using different radiation dose settings on current high-end CT systems: photon-counting detector CT (PCDCT), dual-source energy-integrating detector CT (DECT), and dual-layer spectral detector CT (SDCT). Materials and methods CT scans of a cadaveric human specimen were investigated. …”
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Disturbances of visual perception in non-demented patients with Parkinson’s disease by R. Timofejavaitė, V. Vilda, A. Liveikienė, R. Kaladytė-Lokominienė

“…There is limited data on hallucinations in PD without dementia, considering them mostly iatrogenic. Materials and methods. The permission to perform the study was received at Vilnius University Hospital Santaros Klinikos (VUHSK). 30 self-contained patients of VUHSK with PD without dementia staged 1.0-3.0 according to Hoehn and Yahr scale (19 males and 11 females) were interviewed. …”
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T-lymphocytes FoxP3+ and their interconnection with the severity of coronary atherosclerosis in patients with coronary artery disease and diabetes mellitus type 2: a pilot study by I. V. Kologrivova, O. A. Koshelskaya, T. E. Suslova, O. A. Kharitonova, O. A. Trubacheva, E. S. Kravchenko, A. A. Dmitriukov

“…BACKGROUND: One of the common pathogenic links of diabetes mellitus type 2 (T2DM) and coronary artery disease (CAD) is chronic low-grade inflammation, restricted by FoxP3+ T-regulatory lymphocytes.AIM: To investigate the numbers of FoxP3+CD25hi and FoxP3+CD25lo T-lymphocytes, the subcellular localization of FoxP3 in them, and the production of the main cytokines in relation to clinical and metabolic parameters in patients with association of CAD and T2DM.MATERIALS AND METHODS: An observational single-center single-stage comparative study was conducted. …”
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PULMONARY-RENAL SYNDROME: DIFFICULTIES OF DIFFERENTIAL DIAGNOSIS by D. Yu. Andriyashkina, N. A. Demidova, N. A. Shostak, N. A. Tutaev, A. D. Ershov, D. K. Dudin

“…The study objective is to demonstrate the difficulty of differential diagnosis in pulmonary-renal syndrome using a clinical case as an example.Materials and methods. Male patient A., 68 years old, retired, was hospitalized at the N.I. …”
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Dynamic regulation of Rgs16 and its correlation with Neuregulin1 expression in acute and chronic nerve injury by Marina García-Bejarano, Marina García-Bejarano, Marina García-Bejarano, Riccardo Aucello, Riccardo Aucello, Federica Zen, Federica Zen, Marwa El Soury, Marwa El Soury, Francesca Cordero, Jesús M. de la Fuente, Isabelle Perroteau, Giulia Ronchi, Giulia Ronchi, Giovanna Gambarotta, Giovanna Gambarotta

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