Characteristics of 21 Patients with Secondary Hemophagocytic Lymphohistiocytosis—Insights from a Single-Center Retrospective Study by Radosław Dziedzic, Stanisława Bazan-Socha, Mariusz Korkosz, Joanna Kosałka-Węgiel

“…In this study, we retrospectively analyzed the clinical and laboratory features of patients with secondary HLH to enhance understanding of this life-threatening condition and summarize emerging management strategies. <i>Materials and Methods:</i> This single-center retrospective study analyzed medical records of patients hospitalized with HLH at the University Hospital in Kraków, Poland, from 2013 to 2024, based on HLH-2009 criteria and HScore > 169 points. …”
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The effectiveness of a remote controlled format of speech therapy sessions in restoring patients’ speech after operations for oral and oropharyngeal cancer by E. A. Krasavina, E. L. Choinzonov, D. E. Kulbakin, N. A. Medova, Ch. S. C. Aslonova, M. L. Isaeva, I. G. Kargalskaya

“…The objective of the study was to evaluate the effectiveness of remote controlled format of speech therapy sessions in patients who underwent surgery for oral and oropharyngeal cancers.Methods and materials. The study included 36 patients aged 26 to 68 years, diagnosed with oral and oropharyngeal cancer, with a tumor prevalence of T1-3N0-2M0. …”
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INDEX ASSESSMENT OF PERIODONTAL TISSUE AND ORAL HYGIENE OF PATIENTS AT THE PREOPERATIVE STAGE OF TREATMENT OF GENERALIZED PERIODONTITIS II-III DEGREE by I.M. Futrak

“…The aim of the study was to evaluate the state of periodontal tissues of patients at the preoperative stage of generalized periodontitis ІІ-ІІІІ degree treatment using periodontal and hygienic indices. Materials and Methods. Analysis of periodontal indices (PMA, PBI, Rtg-index, HEC, and tooth mobility score) was performed in 39 patients with GP II degree and 21 patients with GP III degree. …”
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Unlocking urban transportation carbon reduction potential: a dynamic evaluation of public transit adoption in response to carbon-centric policies by Ran Peng, Ran Peng, Ran Peng, Keyuan Ding, Keyuan Ding, Xueliang Liu, Xueliang Liu, Keyu Yao, Keyu Yao, Xu Zhou, Xu Zhou, Wei Zhang, Wei Zhang

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Antimicrobial peptides for treatment of patients with herpes virus-associated chronic prostatitis by E. V. Kulchavenya, S. Yu. Shevchenko, A. A. Baranchukova

“…To determine the efficacy of cytokines-antimicrobial peptides complex in therapy of patients with herpes virus-associated chronic prostatitis.Materials &amp; methods. The pilot, open, prospective, non-comparative study included 23 patients who were followed up for CP for a mean of 9.7 ± 4.2 years. …”
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Treatment of overactive bladder symptoms in women with Diunorm®: preliminary results report by S. V. Shkodkin, M. V. Pokrovsky, S. S. Krasnyak, A. V. Polichuk, S. V. Chirkov, O. V. Churikova, N. A. Kpavtsova

“…To assess the effectiveness and safety of the drug Diunorm® (in caps.) in the prevention and treatment of OAB in women.Materials and methods. The statistical analysis includes the results of a survey of 28 women with symptoms of OAB, whose average age was 35.3 years. …”
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Shock Wave Therapy in the Treatment of Erection Dysfunction: How to Define Clinical Outcomes? A Comparison Between Penile Doppler Ultrasound and a New Visual Erection Hardness Scor... by Mathias Ferreira Schuh, Rodrigo Ribeiro Vieiralves, Luciano Alves Favorito

“…Aim: To demonstrate the effectiveness of LI-ESWT and define the best tool for routine clinical assessment of erectile dysfunction. Materials and Methods: Twenty-one participants with purely vasculogenic erectile dysfunction were selected and randomized to LI-ESWT or placebo. …”
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Efficacy of Esophageal Protector in Treating Gastroesophageal Reflux Disease with Extraesophageal Symptoms: a Multicenter, Open-Label, Observational Study by Yu. A. Kucheryavy, D. N. Andreyev, E. Yu. Eryomina, A. A. Gilmanov, O. V. Nazarova, Ye. A. Sidneva, Yu. G. Topalova

“…Aim: to assess effects of esophageal protector Alfasoxx on extraesophageal symptoms in patients with GERD.Materials and methods. A prospective open multicenter post-registration observational study was conducted. …”
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Cardiotoxicity in patients with metastatic melanoma treated with BRAF/MEK inhibitors: a real-world analysis of incidence, risk factors, and reversibility by Jonas K. Oddershede, Ida K. Meklenborg, Lars Bastholt, Louise M. Guldbrandt, Henrik Schmidt, Rasmus B. Friis

“…This study aimed to evaluate the incidence, timeline, risk factors, and reversibility of BRAFi/MEKi-induced cardiotoxicity in a real-world setting. Patients/materials and methods: Patients with metastatic melanoma (n = 170) treated with Encorafenib/Binimetinib, Vemurafenib/Cobimetinib, or Dabrafenib/Trametinib at Aarhus and Odense University Hospital, Denmark, from 2015 to 2023 were included. …”
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Sexual Function and Quality of Life in Iranian Women With Human Papillomavirus Infection by Afsaneh Tehranian, Marzieh Vahid Dastjerdi, Sare Hatamian, Akram Ghahghaei-Nezamabadi

“… Objective: Considering the prevalence of Human Papillomavirus (HPV) infection and the lack of HPV vaccination program in Iran among young women and the importance of quality of life and sexual performance in women, we decided to conduct a study to examine the relationship between HPV infection and sexual dysfunction and quality of life in Iranian women. Materials and methods: In this cohort study, 250 married women who infected with HPV were recruited via convinence sampling from colposcopy clinic of Arash women hospital (Tehran, Iran) from April 2020 to May 2022.They were evaluated concerning their sexual function in the domains of desire, arousal, lubrication, orgasm, satisfaction and pain with the female sexual function index (FSFI) questionnaire (the total FSFI score is calculated by the sum of the nineteen items). …”
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Nanostructure of Human Aortic Intima in Atherosclerosis (A Pilot Study) by A. M. Golubev, V. V. Moroz, E. K. Kozlova, V. A. Sergunova, O. E. Gudkova, M. A. Golubev, V. N. Kalinichenko, A. M. Chernysh

“…Objective: to analyze the nanostructure of human aortic intima in atherosclerosis and demonstrate the poten tial effect of Niodex on cholesterol plaques.Materials and methods. Samples of intima were taken from those parts of aorta, where different stages of atherosclerotic chages were obvious. …”
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Signaling pathway in breast cancer therapy by Niloofar Mansouri, Melika Daneshgar, Farzaneh Khojasteh, zahra Modaresi, Reza Taheri, Parisa Mokabberi, Mohammad-Reza Saberi, Jamshidkhan Chamani

“…Objective: This research attempted to increase the bioactivity and solubility and reduce the side effects of Tamoxifen (TMX) by using the cellulose nanocrystals (CNCs) extracted from walnut shells as a carrier and studied the interaction behavior of CNCs-TMX with hemoglobin.Materials and Methods: The synthesized CNCs and CNCs-TMX were analyzed through the usage of XRD, FTIR, TEM, SEM, and multi-spectroscopic techniques. …”
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Direct scavenging of ROS by S-PPE NP reduces oxidative stress-induced stimulation of the SESN2/AMPK/KIM-1 pathway in acute kidney injury by Chen Jiao, Hengyi Li, Yongdong Wu, Lemei Hu, Fengzhang Huang, Ming Liang

“…A comprehensive elucidation of the regulatory effects of S-PPE NP on SESN2 and KIM-1 expression in ischemia-reperfusion injury-AKI (IRI-AKI) could enhance therapeutic approaches for AKI.Materials and methods An in vitro human kidney-2 (HK-2) cell hypoxia/reoxygenation (H/R) model and a mouse IRI model were utilized at various time points to assess the expression of SESN2 and KIM-1 and to evaluate the impact of S-PPE NP treatment. …”
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Effect of Nd:YAG Low Level Laser Therapy on Human Gingival Fibroblasts by Andreas S. Gkogkos, Ioannis K. Karoussis, Ioannis D. Prevezanos, Kleopatra E. Marcopoulou, Kyriaki Kyriakidou, Ioannis A. Vrotsos

“…To evaluate the effect of Low Level Laser Therapy (LLLT) on human gingival fibroblasts in terms of proliferation and growth factors’ secretion (EGF, bFGF, and VEGF). Materials and Methods. Primary cultures of keratinized mucosa fibroblasts were irradiated by a Nd:YAG laser 1064 nm with the following energy densities: 2.6 J/cm2, 5.3 J/cm2, 7.9 J/cm2, and 15.8 J/cm2. …”
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Comparative analysis of endocrown fracture resistance and marginal adaptation: CAD/CAM technology using lithium disilicate vs. zirconia-reinforced lithium silicate ceramics by Ezatollah Jalalian, Arash Zarbakhsh, Sotude Khorshidi, Shaghayegh Golalipour, Sara Mohammadnasl, Maryam Sayyari

“…Aims: The present study aimed to compare the fracture resistance and marginal adaptation of endocrowns fabricated using lithium disilicate (LDS) and zirconia-reinforced lithium silicate 9ZLS) ceramics by the computer-aided design and computer-aided manufacturing (CAD/CAM) technology. Materials and Methods: In this in vitro experimental study, 24 extracted mandibular first molars received standard endocrown preparation and were randomly assigned to two groups (n = 12) for the fabrication of endocrowns with ZLS (Suprinity) and LDS (IPS e.max CAD) ceramics. …”
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Review of machine learning applications for predicting the quality of biomass briquettes for sustainable and low-carbon energy solutions by Constance Nakato Nakimuli, Fred Kaggwa, Johan De Greef, David Kilama Okot, Julien Blondeau, Simon Kawuma

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Bibliometric and visualized analysis of research hotpots and future prospects in lacrimal duct obstruction disease (1900 to 2024) by Ming-Hai Chen, Fang Bai, Hai Tao

“…Ophthalmic Plastic and Reconstructive Surgery has published the highest number of related articles, whereas Ophthalmology has the highest co-citation. The current focal points of research include minimally invasive and precise modifications to dacryocystorhinostomy, along with intubation, new materials for stents, and disease pathogenesis. …”
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Qualitative study of patients’ and clinicians’ experiences of an educational intervention for warfarin therapy control in atrial fibrillation in Thailand by Kate Jolly, Jonathan Mathers, Arintaya Phrommintikul, Gregory YH Lip, Chaisiri Angkurawaranon, Rungroj Krittayaphong, Deirdre Lane, Wichuda Jiraporncharoen, Nida Buawangpong, G Neil Thomas, Surakit Nathishuwan

“…Objectives We aimed to understand the (1) perspectives of patients with atrial fibrilation (AF) regarding their experience and implementation of The SAMe-TT2R2 score-guided approach in anticoagulant-nave Thai patients with atrial fibrillation (TREATS-AF) educational intervention for warfarin therapy control, including views on cultural transferability to the Thai context, and (2) healthcare professionals’ (HCPs) experience of implementing the intervention.Design Qualitative research study.Setting Three university hospitals and four tertiary care hospitals in Thailand.Participants 13 newly diagnosed patients with AF and 13 HCPs delivering the TREATS-AF intervention, an intensive structured educational programme.Methods Semistructured interviews. Patient participants were interviewed at two time points: 4 weeks and 6 months after intervention delivery. …”
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Predictors of unfavorable responses to therapy in rifampicin-sensitive pulmonary tuberculosis using an integrated approach of radiological presentation and sputum mycobacterial bur... by Narendran Gopalan, Vignes Anand Srinivasalu, Ponnuraja Chinnayan, Banurekha Velayutham, Adhin Bhaskar, Ramesh Santhanakrishnan, Thirumaran Senguttuvan, Sridhar Rathinam, Mahilmaran Ayyamperumal, Kumar Satagopan, Dhanalakshmi Rajendran, Tamizhselvan Manoharan, Sekar Lakshmanan, Paulkumaran Paramasivam, Dhanalakshmi Angamuthu, Mangalambal Ganesan, John Washington Easudoss Arockia, Ramesh Babu Venkatesan, Venkatesan Lakshmipathy, Shivakumar Shanmugham, Balaji Subramanyam, Shakila Shankar, Jawahar Mohideen Shaheed, Baskaran Dhanaraj, Narayanan Paranji Ramiyengar, Soumya Swaminathan, Padmapriyadarsini Chandrasekaran

“…<h4>Materials and method</h4>We extracted de-identified data from well characterized clinical trial cohorts that recruited rifampicin-sensitive Pulmonary TB patients without any comorbidities, taking their first spell of anti-tuberculosis therapy under supervision and meticulous follow up for 24 months post treatment completion, to accurately predict TB outcomes. …”
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Solid–Liquid Phase Equilibria of the Aqueous Quaternary System Rb⁺, Cs⁺, Mg²⁺//SO₄²⁻ - H₂O at <i>T</i> = 323.2 K... by Zhangfa Yu, Ying Zeng, Xuequn Li, Hongbo Sun, Longgang Li, Wanghai He, Peijun Chen, Xudong Yu

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