Segmented analysis of official statistical indicators dynamic series for osteoarthritis in 1994–2018 in Russia, the North-Western Federal district and the Arkhangelsk region by M. V. Makarova, M. Yu. Valkov

“…To improve the rheumatology service in the Russian Federation, it is necessary to determine the true extent of primary and general incidence of osteoarthritis (OA).The aim of the study is a detailed assessment of trends in the dynamics of OA incidence in the Russian Federation, the North-Western Federal district (NWFD) and the Arkhangelsk region (AR).Materials and methods. We evaluated trends in the dynamics of both incidence and prevalence of OA in the Russian Federation (RF), NWFD and AR in the period 1994–2018 based on data from the annual statistical reports of the Ministry of health of the Russian Federation (form 12). …”
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Evaluating a Low-Fidelity Anesthesiology Simulation for Airway Management and Cardiac Arrest in Medical Students by Kendra Walsh, Christopher Samuel, Shyamal Asher

“…This study describes the development and initial implementation of a low-cost, easy-to-run simulation, assesses participant performance in airway management and ACLS, and reviews qualitative feedback to refine future iterations. Methods:This single-center, prospective observational study piloted a low-fidelity simulation on difficult airway management and intraoperative cardiac arrest for fourth-year medical students in a three-hour workshop. …”
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Understanding of AI large model technology empowering the field of ships by WANG Zhaojie, YU Lei, XIONG Jinhui, LI Huaiyu, HAN Yunjun, SHEN Zhen, GUO Rui, ZHANG Yong

“…Then, from the aspects of the development of intelligent green ships, the innovation of defense equipment systems, the construction of management and control system and the transformation of knowledge-intensive industries, the broad prospect of applying AI large model technologies to the field of ships was discussed. The paper pointed out that the combination of AI large model technologies and concepts such as parallel systems, knowledge factories and digital employees can catalyze new designs, research and development and verification methods such as "AI design" + "digital factory" + "parallel verification". …”
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Therapeutic efficacy of mobilization with movement in early postoperative rehabilitation after unicompartmental knee arthroplasty: a double-blind, randomized controlled trial by Yi Lin, Xingwen Luo

“…Purpose To evaluate the adjunctive effects of MWM on early postoperative functional recovery, pain control, and knee joint stability in patients receiving a standardized rapid rehabilitation protocol for UKA. Materials and methods This double-blind, randomized controlled trial enrolled 72 UKA patients (April 2022–October 2024). …”
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Comparative Evaluation of Universal Periotome and Conventional Techniques in Single-Rooted Tooth Extractions: A Randomized Controlled Study by Swati Sahu, Ankita Barodiya, Animesh Barodiya, Mrunal Dave, Bharani K. Bhattu, Rajat Mohanty, Mahesh Ghadage, Dipooja Patil

“…Background Tooth extraction, one of the most commonly performed dental procedures, is often associated with trauma to the dentoalveolar complex, resulting in pain, gingival laceration, and alveolar bone loss. Materials and Methods This randomized controlled study included 100 patients requiring nonsurgical extraction of single-rooted maxillary or mandibular teeth. …”
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Mean Corpuscular Volume as a Predictive Factor of Response to Preoperative Chemoradiotherapy in Locally Advanced Rectal Cancer by Wen-Yi Zhang, Xing-Xing Chen, Wen-Hao Chen, Hui Zhang, Chang-Lin Zou

“…The aim of this study was to identify if blood routine parameters and serum tumor marker are potential predictive factors for tumor response to preoperative chemoradiotherapy (CRT) in locally advanced rectal cancer. Materials and Methods. 55 locally advanced rectal cancer patients were treated with preoperative CRT in this study. …”
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Percutaneous Vertebroplasty under Local Anesthesia for Osteoporotic Vertebral Compression Fractures: A Prospective Interventional Study by Dhruv Gupta, Varun Kumar Agarwal

“…Aim: The aim of this study was to evaluate the functional outcomes following PVP in OVCFs under local anesthesia. Materials and Methods: This interventional study was conducted between November 2020 and October 2021 in the orthopedic department. …”
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Effect of cementation, cement type and vent holes on fit of zirconia copings by Syed Rashid Habib, Mohsin Ali, Abdulaziz Al Hossan, Ahmad Majeed-Saidan, Mohammad Al Qahtani

“…Objectives: To investigate the effect of cementation, cement type and vent-holes on the marginal and internal fit of Zirconia (Zr) Copings. Materials and methods: Extracted premolars (N = 100) were mounted in resin and prepared for Zr crowns. …”
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Unit for Splitting Degraded Mountain Meadows and Pastures Based on a Mini Tractor by S. M. Dzhibilov, L. R. Guluyeva

“…(Research purpose) To create a small-sized maneuverable splitter for mountain meadows and pastures, to determine its agrotechnical parameters, to give a graphic-analytical substantiation of the splitting working process in areas with a slope of up to 12 degrees. (Materials and methods) A technical examination of the unit laboratory sample was carried out at an altitude of 1540 meters above the sea level. …”
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EFFECT OF STATINS ON SERUM CONCENTRATION OF INFLAMMATORY MARKERS AND MATRIX METALLOPROTEINASES IN PATIENTS WITH ACUTE ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION by TAMARA B. Pecherina, OLGA V. Gruzdeva, OLGA L. Barbarash

“…To assess the effect of pre-hospital administration of statins on the levels of inflammatory markers and matrix metalloproteinases in the se-rum of patients with acute ST-segment elevation myocardial infarction (STEMI).Materials and Methods. We consecutively recruited 175 patients with STEMI (116 (66.3%) men and 59 (33.7%) women, average age 61.3 ± 8.4 years). …”
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Dynamic Smile Evaluation Following Twin Block Appliance Therapy in Class II Division 1 Malocclusion - A Prospective Study by Navneet Singh, Tulika Tripathi, Saumya Kakkar, Priyank Rai, Isha Duggal

“…This study aimed to evaluate and compare dynamic smile before and after twin block therapy. Materials and Methods: This prospective study was conducted on 30 subjects in age group of 11–14 years (mean age = 12.80 ± 1.2 years). …”
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Three-dimensional assessment of the relative position of the roots of the teeth in the anterior lower jaw for treatment planning for class III occlusion anomalies using mini-implan... by V. A. Mazhnikova, A. A. Abramyan, M. M. Shubitidze, Sh. M. Solimanov, A. O. Kuznetsova, R. V. Volberg

“…The use of skeletal support in orthodontics led to the use of elastic traction and mini-implants for upper jaw traction in class III treatment, however, when planning the placement, clinicians did not take into account the anatomical structures of individual areas, that could lead to iatrogenic damage to the endodontium and periodontium.The aim of this study is a three-dimensional assessment of the relative position of the roots of mandibular canines and incisors when planning treatment for anomalies of class III occlusion using mini-implants.Materials and methods. We examined 27 cone beam computed tomography (CBCT) scans in patients aged 20 to 36 years. …”
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An ensemble prediction approach to weekly Dengue cases forecasting based on climatic and terrain conditions by Sougata Deb, Cleta Milagros Libre Acebedo, Gomathypriya Dhanapal, Chua Matthew Chin Heng

“…Additionally, it assessed the impact of building an ensemble model using multiple time series and regression models, in improving prediction accuracy. Materials and Methods: Experimental data were based on two Latin American cities, viz. …”
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Immune Reactivity to Raw and Processed Foods and Their Possible Contributions to Autoimmunity by Aristo Vojdani, Elroy Vojdani, Carina Benzvi, Aaron Lerner

“…However, clinicians are becoming increasingly aware that modern food-processing methods can increase or decrease the immune reactivity of foods, including allergic reactions. …”
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Retrospective Analysis of Transcriptomic Differences between Triple-Negative Breast Cancer (TNBC) and non-TNBC by Çağlar Berkel

“…Molecular differences between TNBC and non-TNBC should be better understood to develop tailored treatment strategies. Materials and Methods: The expression of the most frequently mutated genes, and of genes for which copy number variation events are observed in the highest percentage of breast cancer patients, was compared between TNBC and non-TNBC samples, in R programming environment, using TCGA-BRCA transcriptomics dataset. …”
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Patients' & healthcare professionals' values regarding true- & false-positive diagnosis when colorectal cancer screening by CT colonography: discrete choice experiment. by Darren Boone, Susan Mallett, Shihua Zhu, Guiqing Lily Yao, Nichola Bell, Alex Ghanouni, Christian von Wagner, Stuart A Taylor, Douglas G Altman, Richard Lilford, Steve Halligan

“…<h4>Purpose</h4>To establish the relative weighting given by patients and healthcare professionals to gains in diagnostic sensitivity versus loss of specificity when using CT colonography (CTC) for colorectal cancer screening.<h4>Materials and methods</h4>Following ethical approval and informed consent, 75 patients and 50 healthcare professionals undertook a discrete choice experiment in which they chose between "standard" CTC and "enhanced" CTC that raised diagnostic sensitivity 10% for either cancer or polyps in exchange for varying levels of specificity. …”
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Infiltration level of CPP-ACFP (MI Varnish™), self-assembling peptide P11-4 (Curodont™ Repair), and newly synthesized fluorinated self-assembling peptides in artificial enamel init... by Irina Uzunova-Raycheva, Tanya Nihtyanova, Ralitsa Raycheva, Dancho Danalev, Petya Romanova, Ani Belcheva-Krivorova

“…Aim: The aim of this study was to compare the lesion depth and level of penetration of CPP-ACFP, SAP P11-4 and 2 newly synthesized self-assembling peptides by measuring the linear depth of fluorescence. Materials and methods: A total of 30 enamel samples were prepared from orthodontically extracted permanent premolars. …”
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Calcium hydroxide intracanal medication effects on pain and flare-up: a systematic review and meta-analysis by Ahmed Mohamed Ibrahim, Siza Yacoub Zakhary, Suzan Abdul Wanees Amin

“…ObjectivesThis study aimed to systematically review the pain and flare-up effects of calcium hydroxide (CH) as intracanal medication (ICM) in non-vital mature teeth.Materials and MethodsElectronic-databases searching for published and grey literature and manual searching were conducted. …”
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Combined operations in outpatient laser treatment of chronic hemorrhoids of stage 2–3 by I. A. Matveev, N. A. Borodin, V. T. Dgebuadze, L. A. Morozova, N. N. Povarnin

“…To study the features of transmucous laser thermal ablation of chronic hemorrhoids of stage 2–3 with simultaneous elimination of other anal canal diseases in outpatient settings.Materials and methods. Transmucous ablation of hemorrhoids of 2–3 degrees was performed in 104 (27.5%) people in combination with laser removal of chronic anal fissures in 82 (75%) patients, intra-sphincter fistulas in 10 (9.6%) and other anal canal pathology in 18 (17.4%) patients. …”
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ETIOPATHOGENESIS AND DIAGNOSTICS OF THE MANDIBULAR PERMANENT FIRST MOLARS RETENTION by H.V. Voronkova, L.V. Smagliuk, A.Y. Karasiunok

“…In the literary review, morphological and radiological diagnostic criteria of eruption of first permanent lower molars have been presented. Materials and methods of the research. The article reviews and analyzes literature on the etiology, pathogenesis, early diagnostics of retention of the lower first permanent molars. …”
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