PATIENTS WITH COMBINATION OF CHRONIC HEART FAILURE, HYPERTENSION AND HISTORY OF MYOCARDIAL INFARCTION: CLINICAL AND ANAMNESTIC CHARACTERISTICS, ADMINISTRATION OF ACE INHIBITORS, AN... by M. M. Loukianov, A. N. Kozminsky, S. Yu. Martsevich, S. S. Yakushin, A. N. Vorobyev, A. V. Zagrebelnyy, R. P. Myasnikov, K. G. Pereverzeva, E. A. Pravkina, E. Yu. Andreenko, E. N. Belova, A. D. Deev, V. G. Klyashtorny, E. V. Kudryashov, S. A. Boytsov

“…To assess the clinical and anamnestic characteristics, the prescription rate of angiotensin converting enzyme inhibitors (ACEI)/angiotensin receptor blockers (ARB) and β-blockers in the outpatient practice, adherence to drug therapy in patients with a combination of chronic heart failure (CHF), hypertension (HT) and history of myocardial infarction (MI) in the frame of Cardiovascular Disease Registry (RECVASA). Material and methods. Data analysis in groups of patients with a combination of CHF, HT and the history of MI (n=406) and patients with a combination of CHF, HT and ischemic heart disease (IHD) without history of MI (n=1897) was performed in the frame of RECVASA registry. …”
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Research progress on alkaline earth aluminates for dispenser cathodes by Zichen LI, Yunfei YANG, Yongfeng CAI, Zheng LIU, Junhao SUN, Hongmei LIU, Wenyuan ZHOU, Shizhong WEI, Jinshu WANG

“…In this paper, we review the development history, preparation methods of the impregnants, the active composition within the impregnants, the formation mechanism, and the role of the active substances in cathode performance. …”
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Stress state calculation and potential failure risk identification of LNG storage tank inlet pipeline by Yanbing WANG, Hong ZHANG, Mengying XIA, Hongyu ZHOU, Baisong LI, Qiyu HUANG, Xiaoben LIU

“…However, if internal leakage alongside high cold insulation temperatures occur in the tank top valve, combined with circumferential temperature unevenness caused by non-full flow operation, axial and circumferential stresses may exceed the material’s yield strength at the weld points with unequal wall thickness on the inner surface of the pipeline’s bottom, increasing the risk of crack failure. …”
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Procedure Time of Endovascular Thrombectomy as Performance Measure of Acute Stroke Treatment by Eung-Joon Lee, Han-Yeong Jeong, Jayoun Kim, Nan Hee Park, Min Kyoung Kang, Dongwhane Lee, Jinkwon Kim, Yo Han Jung, Sungwook Yu, Wook-Joo Kim, Han-Jin Cho, Kyungbok Lee, Tai Hwan Park, Mi Sun Oh, Ji Sung Lee, Joon-Tae Kim, Byung-Woo Yoon, Jong-Moo Park, Hee-Joon Bae, Keun-Hwa Jung

“…However, the factors affecting PT and its potential value as a performance measure of AIS treatment remain unexplored. Materials and Methods Using the Korean Stroke Registry, we compared patients who underwent EVT for AIS from 2018 to 2022 based on 60 minutes PT. …”
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Targeted therapy of newly diagnosed <i>FLT3</i>-mutated acute myeloid leukemia. A single-center ambispective cohort study by N. K. Pastukhov, S. N. Bondarenko, A. G. Smirnova, Yu. Yu. Vlasova, D. K. Zhogolev, B. I. Ayubova, O. G. Smykova, N. P. Volkov, I. S. Moiseev, A. D. Kulagin

“…To evaluate the impact of allo‑HSCT performed in first complete remission on the survival of patients treated in combination with midostaurin.   Materials and methods. The study enrolled 276 patients with newly diagnosed AML with FLT3 mutation. 153 of them received combination therapy with midostaurin, 123 – first‑line therapy without FLT3 inhibitors. …”
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SYNTHESIS, ANTIAGGREGATION AND ANTITROMBOTIC ACTIVITIES OF NEW DERIVATIVES OF HYDROXYBENZOIC ACIDS WITH TAURIC FRAGMENT by A. K. Brel, N. V. Atapina, Yu. N. Budaeva, S. V. Lisina, S. S. Tsaruk, D. V. Kurkin, I. N. Tyurenkov

“…An analysis of modern scientific literature revealed the protective effect of taurine in diabetes mellitus and cardiovascular diseases, liver dysfunction, gastrointestinal tract, and kidney diseases.The aim of the article is to study synthesis of new compounds, determination of their physical characteristics and assessment of their antiplatelet and antithrombotic activities in vitro and in vivo.Materials and methods. To confirm the structure of the synthesized new derivatives of hydroxybenzoic acids with a taurine fragment by the acelation method, thin layer chromatography and NMR spectra were used. …”
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Prehospital antibiotics and intravenous fluids for patients with sepsis: protocol for a 2×2 factorial randomised controlled trial by Nick Daneman, Tony Mazzulli, Rob Stenstrom, Gail Klein, Ruxandra Pinto, Lisa Burry, Sheldon Cheskes, Jim Christenson, Damon C. Scales, Anna Rogowsky, Ian R. Drennan, Morgan Hillier, Sandra Jenneson, Philip Moran, Andrew M. Morris, Laurie J. Morrison, Gordon D. Rubenfeld, Christopher W. Seymour, P. Richard Verbeek

“…Initiation of treatments by paramedics at the point of first contact may improve outcomes for these patients.Methods and analysis The study design involves two randomised controlled trials (RCTs) conducted using a 2×2 factorial design comparing use of (1) early intramuscular ceftriaxone versus placebo and (2) an early liberal intravenous fluid strategy (up to 2 L normal saline) versus usual care resuscitation guided by paramedic medical directives. …”
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The impact of preliminary patient hydration on physiological [18F]PSMA-1007 uptake in the urinary bladder on PET/CT by T. L. Antonevskaya, A. I. Khalimon, O. V. Mukhortova, M. M. Khodzhibekova, A. I. Nikiforuk, D. D. Zubkov, G. F. Khamadeeva, D. Yu. Khodakova, T. N. Lazutina, I. V. Pylova, A. V. Leontyev, I. P. Aslanidi

“…The purpose of this study was to assess the impact of preliminary hydration of patients on [18F]PSMA‑1007 uptake in the urinary bladder.Materials and methods. Prospective, multicenter, randomized controlled study included 180 patients with PCa who underwent [18F]PSMA‑1007 PET/CT. …”
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Importance of the profile of inflammatory and anti-inflammatory cytokines in patients with Hepatitis C according to degrees of fibrosis. by Abigail Hernandez-Barragan, Moisés Martínez-Castillo, Adrián Flores-Sánchez, Jesús Dorantes-Alvarez, Isabel Villagómez-López, Marisela Hernandez-Santillan, Andrea Garcia-Avalos, José Luis Pérez-Hernández, Fátima Higuera-De la Tijera, Paula Cordero-Pérez, Linda Muñoz-Espinosa, Gabriela Gutierrez-Reyes

“…Therefore, determining the inflammatory (IFN-γ, TNF-α), and anti-inflammatory (IL-10- IL-1RA) profiles in patients with different degree of liver fibrosis are the important aim in researching of new biomarkers. Materials and Methods: Prospective, cross-sectional and multicenter study; approved through the ethics committee of the UNAM, and the Hospital General de Mexico, patients with chronic Hepatitis C (CHC), and healthy subjects (control group) were included. …”
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Personality, Perinatal Anxiety, and Substance Use as Converging Determinants of Post-Partum Depression in South-East Europe by Oana Neda-Stepan, Catalina Giurgi-Oncu, Adela Bosun, Omar Anwar Saleh Al Nakhebi, Codrina Mihaela Levai, Raluka Albu-Kalinovic, Brenda-Cristiana Bernad, Marius Gliga, Adriana Mihai, Radu Neamțu, Catalin Dumitru, Lavinia Stelea, Camelia Fizedean, Virgil Radu Enatescu

“…We analysed 102 third-trimester women and followed them to six weeks post-partum, and 102 age-matched community controls were used to (i) compare baseline psychological profiles, (ii) chart antenatal-to-post-partum symptom trajectories, and (iii) build an integrated model of clinically relevant PPD (Edinburgh Post-natal Depression Scale, EPDS ≥ 12). <i>Materials and Methods:</i> All 96 raw variables were forward–backward translated from Romanian, reconciled, and harmonized. …”
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Risk factors for head and neck squamous cell carcinoma in disease pathogenesis and prognosis: the importance of smoking cessation and the concept of harm reduction by A. I. Stukan, V. N. Bodnya, V. A. Porkhanov, T. Yu. Semiglazova, O. Yu. Chukhray, E. A. Nefedova, O. N. Nefedov, D. V. Xenodokhov, S. D. Maksimenko

“…To analyze the smoking status and the effect of etiopathogenesis on molecular and clinical features in patients with oropharyngeal squamous cell carcinoma (OpSCC).   Materials and methods. In patients with OPSCC, the smoking status and the level of motivation to its cessation were clarified. …”
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Pepsinogen I as a marker of risk of gastric mucosal cell destruction in Helicobacter pylori-infected patients taking acetylsalicylic acid by I.G. Paliy, S.V. Zaika, А.G. Каpitun, О.М. Muzychuk

“…The purpose was to assess the effect of acetylsalicylic acid (ASA) at a dose of 75 mg on the level of pepsinogen I in patients with сardiovascular disease depending on the Hp status and pantoprazole intake. Materials and methods. The level of pepsinogen I was determined in 82 patients who had been taking ASA at a dose of 75 mg over at least 1 year for сardiovascular disease and had not a history of anti-helicobacter pharmacotherapy, among which 40 individuals had been received pantoprazole, a proton pump inhibitor, at a dose of 40 mg/day for at least 1 month as a gastroprotector at the time of referral. …”
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The Clinical Presentation, Electrocardiogram and Echocardioscopy Features in Case of Acute Coronary Syndrome without ST Elevation Patients of Different Gender with Essential Arteri... by Shved M.

“…To investigate the clinical presentation features, electrocardiogram and echocardioscopy changes acute coronary syndrome without ST segment elevation patients of different age with essential hypertension and Helicobacter pylori infection. Materials and methods. We examined 197 patients that were hospitalized with acute coronary syndrome without ST segment elevation and preexisting essential arterial hypertension with dyspeptic complaints in the Thanscarpathian Regional Clinical Cardiology Dispensary and cardiology intensive care unit in the Central City Clinical Hospital (Uzhhorod). …”
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Effects of GLP-1RAs on cardiovascular outcomes in patients with type 2 diabetes mellitus: review of real-world data on target populations from diabetes registry in Russian Federati... by O. K. Vikulova, G. R. Galstyan, M. V. Shestakova

“…Review the results of several randomized clinical trials (RCTs) concerning effects of GLP-1RA treatments on prevention of primary and secondary cardiovascular events and estimate the number of diabetic target population.MATERIALS AND METHODS. We examined the data from clinical trials on GLP-1RA treatments registered in Russia and used in routine clinical practice (ELIXA, EXSCEL, LEADER, SUSTAIN-6 and REWIND) and data from two meta-analyzes published as of December 1, 2020. …”
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Assessing spatial variability of soil macro fauna and tree canopy using fractal theory (Case study: Riparian Forest of Maroon River) by Shaieste Gholami, ehsan sayad, Hamid Taleshi

“…Consequently, autocorrelation function and fractal theory were used to assess spatial variability of tree canopy and soil macro fauna diversity in Riparian Forest of Maroon River in Khuzestan. 2- Materials and Methods The present study was carried out in Maroon riparian forest of the southeastern Iran (30o 38/- 30 o 39/N and 50 o 9/- 50 o 10/ E). …”
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Intraperitoneal Bupivacaine 0.25% versus intravenous Diclofenac on post-operative analgesia in the cesarean section under spinal anesthesia: A prospective randomized comparative st... by Pragyanrani Panda, Imran Ahmed, Mitesh Kumar Sharma, Rajesh De

“…Aims and Objectives: This study aimed to compare the post-operative analgesic efficacy of IP Bupivacaine with IV Diclofenac in parturients undergoing lower segment CS (LSCS). Materials and Methods: A randomized, double-blind, prospective study was conducted in Deen Dayal Upadhyay Hospital, New Delhi, with 60 patients divided into two groups: Group B received IP Bupivacaine (30 mL, 0.25%) and Group D received IV Diclofenac (1 mg/kg). …”
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Sustained neutrophil infiltration and bacterial grain morphology underlie chronic mycetoma pathology in a murine model by Maria Ruiz-de la Cruz, Anna Vazquez-Marmolejo, Manuel Mejia-Torres, Maria Castro-Corona, Mario Salinas-Carmona

“…Objective(s): This study aimed to characterize the progression of chronic mycetoma caused by Nocardia brasiliensis in a BALB/c murine model, focusing on the interplay between host cellular immune responses, bacterial burden, and histopathological evolution.Materials and Methods: BALB/c mice were inoculated with N. brasiliensis in the left hind footpad to establish the mycetoma model. …”
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Human blood granulocyte degranulation and lysis intensity during interaction with <i>Yersinia pestis</i> in the <i>ex vivo</i> model of bacteriemia by Aleksandr L. Kravtsov, Svetlana A. Bugorkova, Svetlana N. Klyueva, Tatyana P. Shmelkova, Vitaly A. Kozhevnikov

“…The bactericidal effect was determined at different time points during blood incubation at 37оC (for 6 hours) using a microbiological method. …”
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Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study by Tivanani V D Mahendra, Tavva Santhosh Rahul, Santosh Venkata Ramesh Konathala, P Swetha, V Sai Sai Keerthi, Vyshnavi M

“…Purpose: The aim of the present study is to determine the amount of titanium ions released into the artificial salivary medium by modified glass ionomer cement (GIC) doped with 3% and 5% (w/w) titanium dioxide nanoparticles (TiO2-NPs), and to evaluate their antibacterial properties.Materials and methods: 120 cylindrical discs with a diameter of 4 mm and a height of 6 mm were made with 3% and 5% w/w modified GIC containing TiO2 NPs, divided into two groups of 60, and immersed in a chemically synthesized salivary medium. …”
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Students’ perspective on new teaching concepts for medical studies: case- and competency-based learning in radiology by Max Masthoff, Friedrich Pawelka, Gisela Zak, Bas de Leng, Dogus Darici, Philipp Schindler, Walter Heindel, Anne Helfen

“…The format transitioned traditional lectures and seminars to a case- and competency-based course that incorporates technology-enhanced individual case-work, small group discussions, and concise lectures. Materials and methods 235 students (23.5 ± 2.6 years, 72.3% female, 93.3% response rate, November 2023–June 2024) completed a questionnaire before (12 items) and after (20 items) the course, assessing perceived importance of course content, competency gains in abdominal imaging, enjoyment of learning, interest in a radiology career, and pedagogical perception of the teaching concept. …”
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