The dynamics of pre-existing anti-HLA antibodies and the results of kidney transplantation by A. V. Vatazin, A. B. Zulkarnaev, V. A. Stepanov, V. A. Fedulkina

“…To analyze the relationship between the peak panel-reactive antibodies (peak-PRA), the value at the time of transplantation (Tx-PRA) and the results of kidney transplantation.Materials and methods. The study included 287 patients from the waiting list  with anti-HLA antibodies of I and/or II classes. 142 patients underwent transplantation of a cadaveric kidney. …”
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Comparison of Patient Acceptance and Caregiver Satisfaction of Glass-Ionomer Cement vs. Silver Fluoride/Potassium Iodide Application to Manage Molar Incisor Hypomineralisation Hype... by Ramiar Karim, Walaa Ahmed, Mohamed Baider, Christian H. Splieth, Julian Schmoeckel

“…<b>Aim:</b> To compare caregiver satisfaction and children’s acceptance of silver fluoride/potassium iodide (AgF + KI) treatment (Riva Star Aqua^®, SDI Limited, Victoria, Australia) and glass-ionomer cement (GIC) application (Ionostar Plus + Easy Glaze, VOCO, Germany) in reducing hypersensitivity in permanent molars affected by molar incisor hypomineralisation (MIH) with the MIH treatment need index (MIH-TNI) 3 and 4 immediately after its application and after 12 weeks. <b>Materials and Methods:</b> This prospective, comparative, clinical study recruited schoolchildren with at least one hypersensitive MIH molar with a Schiff cold air sensitivity score (SCASS) of 2 and 3. …”
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Machine Learning Model for Early Detection of COVID-19 by Heart Rhythm Abnormalities by M. S. Mezhov, V. O. Kozitsin, Iu. D. Katser

“…The possibility of integrating the results obtained with fitness bracelets and smart watches is shown.Materials and Methods. The work involved an open technology stack: Python, Scikit-learn, Lightgbm. …”
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Evaluation and refinement of thresholds for early migration of total knee replacements as an estimator of late aseptic loosening: an updated systematic review of RSA and survival s... by Raymond Puijk, Jiwanjot Singh, Rowan H Puijk, Elise K Laende, José W M Plevier, Peter A Nolte, Bart G C W Pijls

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Complications of lung cancer radiation therapy and the preventive role of positron-emission tomography by O. Yu. Stoliarova, Yu. V. Dumanskyi, O. V. Syniachenko, Ye. D. Yehudina, O. O. Khaniukov

“…The purpose of study: to investigate the nature of the RT complications in various options of the LC course, to identify the risk factors and to assess the role of the preliminary PET with fluoride-dehydroglucose in order to reduce the number of side effects of irradiation. Materials and methods. 1071 patients with LC at the ages from 24 to 86 years (mean age 59 years) were observed (83 % of men and 17 % of women). …”
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Increased Serum EphA2 is Associated with Disease Severity in Pediatric Patients with Asthma by Ma S, Qu W

“…However, this study aimed to evaluate the association between a novel biomarker, EphA2, in two distinct pediatric asthma populations stratified by disease severity.Materials and Methods: Serum levels of interleukins (IL-1β, IL-4, IL-6, IL-8, IL-13), tumor necrosis factor-α (TNF-α), transforming growth factor-β 1 (TGF-β 1), matrix metalloproteinase (MMP-2 and MMP-9), and EphA2 were measured by ELISA in all participants. …”
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Hemostatic imbalance underlying preterm delivery in COVID-19 convalescent patients by M. G. Nikolaeva, A. V. Korchagina, A. P. Momot, E. V. Grigoreva

“…Aim: to study the role of the hemostatic system in pretem delivery in pregnant women who have had COVID-19 in the gestation period from 14 to 16 weeks.Materials and Methods. A prospective single-center observational study was conducted by enrolling 63 pregnant women with verified COVID-19 at 14–16 weeks of gestation. …”
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Comparative Evaluation of Oral Melatonin versus Oral Alprazolam as Premedication in Patients Undergoing Tympanoplasty: A Randomised Control Study by Nupoor, Shikha Agarwal, Harsh Vardhan, Nikhil Nayar

“…Aim: To compare the effects of oral melatonin versus oral alprazolam as premedication and their impact on postoperative recovery characteristics in patients undergoing tympanoplasty. Materials and Methods: In this randomised controlled study which was conducted from August 2022 to March 2024 at the Department of Anaesthesiology, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India, a total of 70 adult patients were randomly allocated into two groups. …”
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Prognostic values of the diastolic index as a marker of chronic heart failure with preserved left ventricular ejection fraction by V. V. Syvolap, V. A. Lysenko

“…To prove the diagnostic and prognostic value of the diastolic index as an additional criterion for the HFpEF phenotyping in the European population. Materials and methods. The study enrolled 88 patients (men – 46.6 % (n = 41); women – 53.4 % (n = 47)) with CHF of ischemic origin, stage II A–B, NYHA class II–IV. …”
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DIFFERENT RESPONSE OF HUMAN BLOOD NEUTROPHIL FCᵧRIIIB (CD16) TO EX VIVO MODELING OF BACTEREMIA BY PATHOGENIC AND OPPORTUNISTIC MICROORGANISMS by Alexander Leonidovich Kravtsov, Svetlana Nikolaevna Klyueva, Tatyana Petrovna Shmelkova, Vitaly Alexandrovich Kozhevnikov, Svetlana Aleksandrovna Bugorkova

“…The purpose of the work was to compare the ex vivo reaction of human neutrophil FcᵧRIIIb in response to the addition in blood the live cells of  opportunistic (Escherichia coli, Staphylococcus aureus) and pathogenic (Yersinia pestis, Brucella abortus) bacterial species. Materials and methods. The density of CD16 expression on NG was determined by flow cytometry in arbitrary fluorescence intensity units (MFI) after staining leukocytes with CD45-FITC and CD16-PE reagents (Backman Coulter, USA) when immunophenotyping them in the blood according to the Lyse/No-Wash protocol. …”
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BIOMECHANICAL STUDY OF SINGLE ROOTED TEETH RESTORED WITH DOWEL CORS by M. M. Klepach, B.Y. Silenko, T. A. Khmil, M. V. Khrebor, Y. I. Silenko

“… The purpose of the biomechanical study was a comparative analysis of the stress-strain state of the dowel core, dentin of the tooth root, periodontal and bone tissues of the alveolus in the restoration of the first premolars using dowel core, made of zirconium oxide. Materials and methods. Mathematical modeling was carried out using a service modeling and finite element analysis NASTRAN, designed for implementation on a personal computer in a Windows environment. …”
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Evaluation of the Efficiency of a Soft Dosage Form for the Treatment of Osteoarthritis: Influence on the Level of Pro-inflammatory Cytokines by U. V. Nogaeva, V. E. Kovanskov, D. Yu. Ivkin, E. V. Flisyuk, K. D. Yakimov, E. I. Yeletskaya, E. D. Semivelichenko, V. G. Antonov

“…Evaluation of the effect of a previously developed soft dosage form containing meloxicam, a purine derivative and an immunomodulator M on the level of pro-inflammatory cytokines: IL-1α, IL-1β, IL-6 and TNF-α in osteoarthritis.Materials and methods. The experiment included 25 animals, which were divided into 5 groups by simple randomization: 1 – test (gel 0.5 %), 2 –test (gel 1 %), 3 – reference (Amelotex®, gel 1 %), 4 – control (gel base); 5 – intact. …”
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Prediction of Mortality in ICU Patients with SARS-CoV-2-Associated Pneumonia by P. N. Savilov, S. S. Kurdyumova, S. V. Shutova, S. V. Buchneva, A. V. Baranov

“…Aim: to determine the predictive value of selected routine clinical and laboratory parameters and to assess their prognostic significance for modeling mortality risk in intensive care unit (ICU) patients with SARS-CoV-2-associated pneumonia.Materials and Methods. A retrospective case-control analysis of 73 medical records was performed. …”
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Is the both column fixation corridor a universally valid and consistent fixation pathway in pelvic and acetabular surgery? by Vedat Öztürk, Malik Çelik, Murat Tıngır, Furkan Özönder, Cemal Kural, Mustafa Gökhan Bilgili

“…This study aims to validate the BCFC as a consistent fixation pathway across genders, evaluate its axial fluoroscopic visualization, and investigate gender-specific anatomical variations for surgical planning. Materials and methods In this study, pelvic CT data from 400 adults (200 males, 200 females) were analyzed using Fujifilm-Synapse 3D software. …”
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Comparative immunohistochemical characteristics of expression of estrogen receptors-alpha, progesterone receptors, p16, p53, Ki-67 and caspase 3 in invasive endometrial adenocarcin... by V. A. Tumanskiy, A. V. Chepets

“…To characterize the expression of the estrogen receptors-alpha, progesterone receptors, p53, p16, ki-67 and caspase 3 in the invasive endometrioid endometrial adenocarcinoma compared with the normal proliferative endometrium. Materials and methods. The uteruses of 56 women with the verified diagnosis of endometrial cancer (stage pT1-4MxNx) and biopsies of 30 women with normal proliferetive endometrium were analyzed. …”
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Epidemiology of Vancomycin-Resistant Enterococci in Various Medical Wards by A. V. Liubimova, N. A. Shalyapina, V. V. Kolodzhieva, S. A. Riachovskich, O. V. Dmitrieva, T. V. Brodina, A. A. Shishmakov

“…The aim of this study was to define hospital units with high risk of VRE dissemination in health care facilities of St. Petersburg. Materials and Methods. Point-prevalence study of colonisation and infection in patients and contamination of the environment was conducted during 2013 - 2014 in 8 hospital units of different types: neonatal intensive care, newborn pathology, general paediatric surgery, bone marrow transplantation (BMT for adolescents), cancer surgery of the gastrointestinal (GI) tract and breast cancer, haemodialysis (three units). …”
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Epidemiological characteristics of diabetes mellitus in the Russian Federation: clinical and statistical analysis according to the Federal diabetes register data of 01.01.2021 by I. I. Dedov, M. V. Shestakova, O. K. Vikulova, A. V. Zheleznyakova, M. А. Isakov

“…The aim of our study was to analyze a dynamic (2016–2020) of the epidemiological characteristics of diabetes mellitus in the Russian Federation (prevalence, morbidity, mortality), the prevalence of complications, the level of HbA1c and the dynamics of the structure of glucose-lowering therapy (GLT) according to the Federal Diabetes Register (FDR).MATERIALS AND METHODs. The database of FRD (http://diaregistry.ru) 84 regions of the RF. …”
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AFFECTIVE DISORDERS AND QUALITY OF LIFE IN PATIENTS WITH CORONARY HEART DISEASE ACCORDING TO PSYCHOMETRIC TESTS DATA by S. Yu. Mukhtarenko, T. M. Murataliev, Z. T. Radzhapova, Yu. N. Neklyudova

“…The aim was to study the frequency and severity of affective disorders and quality of life in patients with coronary heart disease (CHD): unstable and stable angina of II–III functional class.Materials and methods. 488 patients with verified CHD were examined to identify and assess anxiety-depressive spectrum disorders by the screening questionnaire of Moscow Research Institute of Psychiatry, Ministry of Health of Russia. 172 patients with CHD from the screening group – 96 (55.81 %) patients with unstable angina and 76 (44.19 %) with stable angina, 136 (79.07 %) men and 36 (20.93 %) women were examined with psychometric tests: Hospital Anxiety and Depression Scale (HADS) and Beck Depression Inventory (BDI). …”
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“Restoration of the Past Scenery-Realm”: A Research on the Scenery-Realm Restoration of Jiang’s Fu Garden During Qing Dynasty in the Historical Revolution of the Humble Administrat... by Qian BIAN

“…However, due to the limitations imposed by the differences in research subjects and the insufficiency of historical materials before, the key questions of what had been “fu” (restored) in this garden and what qualified the garden as a “fu” (restoration) of the past scenery-realm have not been sufficiently elucidated.MethodsThis research employs targeted searches within the Suzhou Library’s Ancient Book Database to augment the existing corpus of literature pertaining to Jiang’s Fu Garden. …”
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The influence of intermittent venovenous hemodiafiltration on the course of acute kidney injury in multiple trauma victims by V.M. Dubyna, O.V. Kravets

“…Materials and methods. Fifty victims with multiple trauma complicated by rhabdomyolysis and AKI were examined. …”
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