Clinical manifestations, histopathological changes and quality of life in patients with advanced knee osteoarthritis caused by age, trauma, obesity and their combination by Kristina V. Korochina, Tatyana V. Chernysheva, Irina E. Korochina

“…Objective — to reveal and analyze clinical characteristics, knee joint histopathology, and quality of life in patients at late stages of knee osteoarthritis (OA) triggered by age, trauma, metabolic syndrome, or their combination. Material and methods — We studied 120 subjects with knee OA (sensu Altman R.D., 1991) of Kellgren-Lawrence Grades 3-4. …”
Get full text

Prognostic value of FOXA1 in patients with Т1–2N0M0 breast cancer by R. M. Paltuev, A. G. Kudaybergenova, V. F. Semiglazov, A. V. Komyakhov, A. I. Tseluyko

“…To evaluate the prognostic value of FOXA1 in patients with T1–2N0M0 breast cancer.Materials and methods. We measured FOXA1 expression in tumor cells of patients with hormone-dependent and hormone-independent breast cancer using the method developed by us (patent No. …”
Get full text

Generation of LDPM structure formed by Voronoi cells by Jan Vozáb, Jan Vorel

“… A preliminary study of an approach to internal structure generation used in lattice discrete particle models (LDPMs) [1]. The presented method used for particle generation and placement is intended to help realistically capture the internal structure of materials. …”
Get full text

SYNTHESIS AND ANTIOXIDANT ACTIVITY OF (E)-3-(3-(4-OXO-4H-CHROMEN-3-YL)ACRYLOYL) 2H-CHROMEN-2-ONE DERIVATIVES by S. S. Shatokhin, V. A. Tuskaev, S. Ch. Gagieva, D. I. Pozdnyakov, E. T. Oganesyan

“…The aim is based on the results of the in silico prediction, to obtain and characterize a number of (E)-3-(3-(4-oxo-4H-chromen-3-yl)acryloyl)-2H-chromen-2-one derivatives, and also to study their antioxidant activity.Materials and methods. The synthesis of the target compounds was carried out by condensation of substituted 3-formylchromones and 3-acetylcoumarins under the acid catalysis conditions. 1H NMR spectra were recorded on the instruments of Bruker Avance-400 (400 MHz) and Bruker Avance-300 (300 MHz) in the solutions of CDCl3 or DMSO-d6. …”
Get full text

Total cement knee arthroplasty in patients of 85–95 years old with terminal stage of degenerative knee disease by V. Yu. Murylev, P. M. Elizarov, A. V. Muzychenkov, Ya. A. Rukin, A. A. Dering, G. A. Kukovenko, S. S. Alekseev, G. G. Rubin

“…The objective of the study is to make the analysis of the results of total cement knee arthroplasty in the most difficult age group of 85–95 years old patients.Material and methods. 40 patients with terminal knee arthrosis were selected based on their comorbidity.Results. …”
Get full text

REHABILITATION EFFECT OF CORRECTION OF ERECTILE DYSFUNCTION IN PATIENTS WHO UNDERWENT RADICAL PROSTATECTOMY FOR PROSTATE CANCER by A. T. Asratov, I. V. Vinogradov, B. R. Gvasaliya, A. A. Kachmazov, A. G. Kochetov, Yu. V. Samsonov, N. V. Sitnikov, A. O. Tolkachev, A. A. Kostin

“…To investigate the effect of the development of erectile dysfunction (ED) in patients with prostate cancer after radical prostatectomy (RPE) on the assessment of these patients’ quality of life and their psychological state and the influence on these parameters of ED treatment by implantation of the prosthesis of the penis.Materials and methods. The material of the study was analysis of the questionnaire data of 30 patients with PC with the postoperative ED before the postoperative period and after the falloprosthesis. …”
Get full text

Surface Roughness, Microhardness, and Microleakage of a Silorane-Based Composite Resin after Immediate or Delayed Finishing/Polishing by Fernanda Carvalho Rezende Lins, Raquel Conceição Ferreira, Rodrigo Richard Silveira, Carolina Nemésio Barros Pereira, Allyson Nogueira Moreira, Claudia Silami Magalhães

“…This study evaluated the effect of immediate or delayed finishing/polishing using different systems on the surface roughness, hardness, and microleakage of a silorane-based composite. Material and Methods. Specimens were made with silorane-based composite (Filtek P90, 3M ESPE) and assigned to the treatments: control (light-cured); aluminum oxide discs (Sof-Lex, 3M ESPE); diamond-impregnated silicone tips (Astropol, Ivoclar Vivadent); aluminum oxide-impregnated silicone tips (Enhance, Dentsply). …”
Get full text

The use of thromboaspiration and combined treatment in patients with ischemic stroke in real-life clinical practice by T. V. Volchenkova, S. V. Kotov, E. V. Isakova, M. V. Sutormin, E. V. Patrin, B. B. Gegenava, M. N. Martynovich, I. G. Rudakova, L. V. Smetana, V. A. Borisova, S. V. Belkina

“…Objective: to evaluate the efficacy and safety of mechanical thromboextraction and staged reperfusion therapy with alteplase in real clinical practice. Material and methods. The study included 106 patients who were retrospectively divided into two groups: Group I underwent staged reperfusion therapy (intravenous thrombolysis with alteplase followed by aspiration thromboextraction), Group II underwent thromboaspiration only. …”
Get full text

Role of Early Clinical Exposure in Medical Education: Effectiveness of Its Transition from Onsite to Online Sessions during the Pandemic by Shobha C Ramachandra, Swetha N Kempegowda, Kusuma K Shivashankar, Abhijith Devaraju, Suma M Nataraj, Akila Prashant

“…Introduction: We implemented online early clinical exposure (ECE) for medical undergraduate students during the pandemic and analyzed their feedback to assess the effectiveness of the session. Materials and methods: An online ECE on “Inborn Errors of Metabolism (IEM) and the Significance of Newborn Screening (NBS)” was scheduled, during which the participants were provided with information pertaining to the prevalence, morbidity, mortality, significance of NBS, and available treatment modalities that are currently accessible. …”
Get full text

Grinding power model for flute grinding of solid tools based on equivalent chip thickness by Lei REN, Jiangtao PAN, Daohui XIANG, Junjin MA, Xiaobin CUI

“…A grinding power model for flute grinding of solid tools is proposed based on equivalent chip thickness, aiming to achieve precise prediction and control of grinding power for flute grinding.MethodsA kinematic model for flute grinding is established using homogeneous coordinate transformation. …”
Get full text

Artrosis de rodilla asociada a deformidad extraarticular tratada mediante prótesis total de rodilla y osteotomía correctora de forma simultánea by L. Arbeloa-Gutierrez, A. Arenas-Miquelez, J. de Pablos

“…Our objective is to present a surgical option in cases of severe knee arthritis associated with an EAD (indications, mechanical planning and surgical technique), pros and cons and discuss the results with this one-stage technique. Material and methods: We retrospectively reviewed all cases of severe KOA associated with EAD treated surgically in our institution from 2010-2016. …”
Get full text

[Translated article] Knee osteoarthritis associated with extra-articular deformity treated by total knee arthroplasty plus simultaneous corrective osteotomy by L. Arbeloa-Gutierrez, A. Arenas-Miquelez, J. de Pablos

“…Our objective is to present a surgical option in cases of severe knee arthritis associated with an EAD (indications, mechanical planning and surgical technique), pros and cons and discuss the results with this one-stage technique. Material and methods: We retrospectively reviewed all cases of severe KOA associated with EAD treated surgically in our institution from 2010 to 2016. …”
Get full text

The role of total hip arthroplasty in the treatment of patients with floating hip after polytrauma by S.O. Guryev, P.V. Tanasiienko, I.V. Kovalyshyn

“…Our study purposed to test and evaluate the effectiveness of total hip arthroplasty (THA) in patients with a floating hip as a result of polytrauma. Materials and methods. We analyzed the treatment of 77 cases of ipsilateral hip fractures as a result of polytrauma. …”
Get full text

Improved detection of air trapping on expiratory computed tomography using deep learning. by Sundaresh Ram, Benjamin A Hoff, Alexander J Bell, Stefanie Galban, Aleksa B Fortuna, Oliver Weinheimer, Mark O Wielpütz, Terry E Robinson, Beverley Newman, Dharshan Vummidi, Aamer Chughtai, Ella A Kazerooni, Timothy D Johnson, MeiLan K Han, Charles R Hatt, Craig J Galban

“…<h4>Objective</h4>To investigate the effectiveness of a convolutional neural network (CNN) model for quantifying and monitoring AT, and to compare it with other quantitative AT measures obtained from threshold-based techniques.<h4>Materials and methods</h4>Paired volumetric whole lung inspiratory and expiratory CT scans were obtained at four time points (0, 3, 12 and 24 months) on 36 subjects with mild CF lung disease. …”
Get full text

Thermal Conductive Polyamide-6/Polyolefin Elastomer/Aluminum Nitride/Aluminum Oxide Composites by Marjan Shahmir, Shervin Ahmadi, Hassan Arabi

“…Hypothesis: Polyamide-based blends, like most polymers, are thermally insulating materials, which restrict their application. An effective method to improve the thermal conductivity of polymers is manipulating the morphology and locating conductive fillers selectively at the polymer interfaces to induce heat conduction path way. …”
Get full text

Possibilities of radionuclide diagnostics of Her2-positive breast cancer using technetium-99m-labeled target molecules: the first experience of clinical use by O. D. Bragina, V. I. Chernov, E. Yu. Garbukov, A. V. Doroshenko, A. G. Vorobyeva, A. M. Orlova, V. M. Tolmachev

“…To study the possibility of clinical use of a radiopharmaceutical based on technetium-99m-labeled target molecules for the diagnosis of breast cancer with the Her2/neu overexpression in humans.Materials and methods. The study included 11 patients with breast cancer (T1–4N0–2M0) before systemic therapy: 5 with Her2/neu overexpression; expression of the marker was not detected in 6. …”
Get full text

Analysis of the Aroma Composition of Different Varieties of Apricot Wine by Jieling Wu, Mingguang Chen, Chao Xu, Lei Qiu, Wenxiao Hu, Xiaomin Xue, Xianyan Zhao

“…In order to explore the quality of apricot wine obtained by fermentation of different varieties of apricots and the typical volatile substances in apricot wine, and to find apricot varieties that can brew better quality apricot wine, the gas chromatography-mass spectrometry (GC-MS) method was used to detect Jinkaite, Katy, Jintaiyang apricots and brewed apricot wine, and the correlation and difference of key odour substances were analyzed. …”
Get full text

ORTHODONTIC AND ORTHOPEDIC REHABILITATION OF PATIENTS WITH CLEFT OF UPPER LIP, ALVEOLAR SURGERY, HARD AND SOFT PALATE by O.M. Makarova, M.V. Semenyaka, G.M. Balya, V.D. Kuroyedova

“…So, removable milled caps are the modern optimal method of temporary long-term prosthetics, which greatly improve the functional and aesthetic status of the patient. …”
Get full text

Comparison of the effects of coronary artery anastomosis training between senior and junior surgeons by Bo Li, Xiaokang Luo, Lei Qi, dong Zhang, Fuliang Luo, Bin Li, Yue Tang

Get full text

LONG-TERM OUTCOMES OF SPINKTER-SPARING SURGERIES IN MID- AND LOWER AMPULLARY RECTAL CANCER: QUALITY OF LIFE AND SURVIVAL OF PATIENTS by A. A. Medvednikov, A. V. Shelekhov, V. V. Dvornichenko, R. I. Rasulov, S. M. Plenkin, N. V. Popova, A. G. Zakharov, N. A. Nikolaeva, S. I. Radostev, A. A. Litvintsev

“…The purpose of the study was to comparatively analyze surgical outcomes in patients with histologically proven rectal cancer. Material and methods. From 1999 to 2012, 174 patients with histologically proven rectal cancer underwent abdominal-anal resection of the rectum with bringing down the sigmoid colon into the anal canal and sphincter-preserving low intra-abdominal resection of the rectum with coloanal anastomosis.Results. …”
Get full text