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4681
Creatine phosphate preconditioning reduces ischemiareperfusion injury in isolated rat heart
Published 2021-10-01“…To study the effect of simultaneous administration of creatine phosphate immediately before ischemia on cardiodynamic parameters and biomarkers of oxidative stress in the coronary venous blood flow during retrograde perfusion in an isolated rat heart.Materials and methods. 20 Wistar albino rats were divided into 2 groups: group 1 (control) and group 2 (experimental), 10 rats per group. …”
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4682
Accuracy of segment anything model for classification of vascular stenosis in digital subtraction angiography
Published 2025-05-01“…Abstract Background This retrospective study evaluates the diagnostic performance of an optimized comprehensive multi-stage framework based on the Segment Anything Model (SAM), which we named Dr-SAM, for detecting and grading vascular stenosis in the abdominal aorta and iliac arteries using digital subtraction angiography (DSA). Materials and methods A total of 100 DSA examinations were conducted on 100 patients. …”
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4683
Anemia and comorbidity in people over 65: data from the Russian study EUCALYPTUS
Published 2025-01-01“…To investigate the relationship between anemia and comorbidity in patients aged 65 years and older. Materials and methods. The results of a sub-analysis of the multicenter cross-sectional study EUCALYPTUS, which involved 4308 people (30% of men) aged 65 to 107 years (average age – 78 years), are presented. …”
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4684
Navigating electives: Perspectives from phase III MBBS students and faculty in program evaluation
Published 2025-06-01“…Aims and Objectives: To assess perceptions and challenges faced by students and teaching faculty to provide insights about the best approach to implement electives. Materials and Methods: A cross-sectional survey in which qualitative data on perceptions of electives were collected through an online survey by a validated semi-structured questionnaire with open-ended questions. …”
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4685
Molecular genetic predictors of metastatic lesions of regional lymph nodes in patients with breast cancer
Published 2021-10-01“…Objective: to identify molecular genetic predictors of metastatic spread to regional lymph nodes in patients with breast cancer (BC) based on the analysis of gene expression profile of the primary tumor.Materials and methods. The study included 358 patients with BC who underwent surgical treatment in breast cancer department of Academician V.I. …”
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4686
On some problems of using digital technologies in the process of realizing individual rights and freedoms
Published 2023-07-01“…The relevance of thisresearch topic is expressed in the need to identify the main problems of using digital technologies in the process of realizing individual rights and freedoms. Materials and Methods. Based on a critical analysis of the provisions of legislation and various points of view that have developed in the general theory of law and branch sciences, the problems of using digital technologies in the process of realizing individual rights and freedoms have been identified. …”
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4687
Statistically based algorithm for differential diagnosis of arthropathies based on quantitative osteoscintigraphy
Published 2021-07-01“…EULAR experts include osteoscintigraphy of joints in the list of promising methods for the diagnosis of joint diseases. However, the method remains little used in rheumatology in our country.Aim of the study – to develop an algorithm for differential diagnosis for the most common arthropathies based on quantitative osteoscintigraphy.Materials and methods. 3 hours after the injection of pyrophosphate labeled with Tc-99m, scintigraphy of skeletal bones was performed according to the “whole body” program. …”
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4688
Determination of the Machine and Tractor Fleet Optimal Composition for a Model CottonTextile Cluster
Published 2021-06-01“…(Research purpose) To calculate the required amount of agricultural machinery based on the established standards. (Materials and methods) The authors developed an algorithm for determining the standard coefficients of the equipment necessity per 1000 hectares of arable land. …”
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4689
Tasks of zemsky self-government bodies (March – October 1917) and ways to solve them
Published 2025-08-01“…The purpose of the work is to study the manifesta-tions and results of the process of reforming zemstvo self-government in revolutionary Russia. Materials and methods. The implementation of research tasks was achieved on the basis of the use of articles of the journal “Zemskoe Delo” which was published under the editorship of prominent theorists and practitioners of local self-government of pre-revolutionary Russia – Boris Borisovich Veselovsky (1880–1954) and Dmitry Dmitrievich Protopopov (1865–1934) in St. …”
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4690
On the Classification of Regions of the Russian Federation by Level of Socio-Economic Development and Innovation Activity Index
Published 2024-05-01“…The purpose of the study is to form an effective tool for classifying the regions of the Russian Federation in the context of innovation activity under technological constraints.Materials and methods. The information and empirical base of the research consists of Decrees of the President of the Russian Federation, normative legal acts of the Government of the Russian Federation, and open set of statistical data provided by the Federal State Statistics Service. …”
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4691
Effect of low-level laser therapy on pain reduction in orthodontic patients during molar distalization: A randomized controlled trial
Published 2024-02-01“…Aim: To investigate the effects of low-level laser therapy (LLLT) on pain reduction in orthodontic patients during molar distalization. Materials and methods: Twenty patients requiring bilateral maxillary first molar distalization were randomly assigned to two groups: the intervention group (mean age 15.61 ± 1.03 years) received multiple LLLT after every activation of the distalizing appliance (immediately and on the 3rd, 7th, and 14th days) and the control group (mean age 15.64 ± 1.08 years) who did not receive LLLT. …”
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4692
Oxidative Stress in Postoperative Atrial Fibrillation: Does Malondialdehyde Hold Predictive Value?
Published 2025-04-01“…This study aimed to assess the association between serum MDA levels and POAF incidence in patients undergoing cardiac surgery. <i>Materials and Methods</i>: This prospective observational study included 99 consecutive patients undergoing elective on-pump cardiac surgery. …”
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4693
Medication misuse and illicit substance use among palliative care patients in German palliative care units– an evaluation from the perspective of palliative care providers
Published 2025-03-01“…This study aims to explore how practitioners perceive the issue and management of substance misuse in palliative care patients. Materials and methods Following an extensive literature review, a 23-question questionnaire was developed to assess attitudes and practices related to substance misuse in palliative care and distributed to all German palliative care units (PCUs) listed on the website of the German Society for Palliative Medicine (n = 334). …”
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4694
Configuring thermal ablation volumes for treatment of distinct tumor shapes: a repeatability study using a robotic approach
Published 2024-12-01“…The aim of this study was to evaluate the repeatability of a novel robotic approach for configurable ablation of distinct tumor shapes and compare it to the standard ablation technique for creating ellipsoidal ablation volumes.Materials and methodsThe repeatability was evaluated in terms of width variability in created ablation volumes. …”
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4695
APELIN-12 AND APELIN-36 IN SPUTUM OF PATIENTS WITH BRONCHIAL ASTHMA
Published 2017-06-01“…However, the available literature contains no research on the content of apelin – this newly discovered adipokine – in sputum.The aim is to detect the presence of two isoforms of apelin: apelin-12 and apelin-36 in BA in the target organ (in sputum) and to establish their possible participation in the pathogenesis of the disease.Materials and methods. 13 patients with bronchial asthma (BA) with different variants of the disease were examined. …”
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4696
Conduction studies of phrenic nerve in healthy children
Published 2018-07-01“…The objective is to investigate the M-wave latency and amplitude in electroneurographic (ENG) examination of the phrenic nerve in healthy children of different ages for development of a normative database of neurophysiological data.Materials and methods. 48 healthy children (28 girls and 20 boys) were examined. …”
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4697
Positive mental states and their relation to psychosocial resources: protocol of a systematic review focusing on cultural moderators
Published 2025-08-01“…Correlates, that is, psychosocial resources, of positive mental states may represent a starting point for those interventions. To date, a comprehensive systematic review on those correlates is still missing as well as knowledge on culture-related differences.Methods and analysis A systematic review and meta-analysis on the longitudinal link between psychosocial resources (eg, income, optimism, social support and community coherence) and hedonic and eudaimonic positive mental states (eg, life satisfaction, happiness and forward-looking attitude) will be conducted. …”
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4698
Analysis of Pharmacokinetic Parameters of Acetylsalicylic Acid for Prediction of Potential Nephrotoxic Effects
Published 2021-12-01“…The study of the pharmacokinetics of acetylsalicylic acid products will contribute to timely detection and correction of side effects caused by this medicinal product.The aim of the study was to evaluate potential nephrotoxic effects following a single oral administration of 75 mg of acetylsalicylic acid, based on the analysis of the pharmacokinetic parameters.Materials and methods: the study involved 24 healthy volunteers who received 75 mg of acetylsalicylic acid (tablets) once orally. …”
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4699
Problematic Smartphone Use and its Association with Sleep Disturbances: A Cross-sectional Study
Published 2025-06-01“…Aim: To examine the association between Problematic Mobile Phone Use (PMPU) and SQ among adults, highlighting its potential impact on sleep patterns and overall wellbeing. Materials and Methods: This cross-sectional study was conducted at Indira Medical College and Hospitals, Tiruvallur, Tamil Nadu, India from January to June 2024. …”
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4700
On the choice of a solution for cavitation in the complex treatment of postpartum endometritis
Published 2024-06-01“…The purpose of our study was a comparative assessment of the effectiveness of the use of various liquids during ultrasonic cavitation in the treatment of postpartum endometritis.Materials and methods. 80 patients with mild and moderate severity of the disease were examined and treated. …”
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