Baseline Raman Spectral Fingerprints of Zebrafish Embryos and Larvae by Isabel Oliveira Abreu, Cláudia Teixeira, Rui Vilarinho, A. Cristina S. Rocha, Joaquim Agostinho Moreira, Luís Oliva-Teles, Laura Guimarães, António Paulo Carvalho

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About Epizootic Situation on Major Helminthosis of Different Breeds of Pigs in Georgia by L. M. Udzhmadzhuridze, Sh. O. Potskhveriya, R. S. Mitichashvili, T. V. Kiliptari

“…The purpose of the research is to study the epizootic situation on major helminthosis of different breed groups of pigs in Georgia. Materials and methods. Genetical and craniological researches of Kakhetian pigs have been conducted according to common methods at the Institute of cytology and genetics of Siberian Branch of the USSR Academy of Science and at the subdepartment of live-stock animals breeding and genetics of Georgia Zooveterinary Research Institute. …”
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Do We Have a Place for Non-Steroidal Anti-Inflammatory Drugs in Corneal Refractive Surgery? by N. V. Maychuk, I. A. Mushkova, M. R. Obraztsova

“…To study the clinical efficacy and safety of Broxinac (0.09 % bromfenac solution) in the early postoperative period of corneal refractive surgery.Materials and methods. The study included 168 patients (168 eyes) with moderate and high myopia after PRK (24 eyes), FemtoLASIK (78 eyes) and ReLEx SMILE (66 eyes), divided into equal subgroups: in the main group, Broxinac was instilled once 30 minutes after the operation, and in the control group — placebo. …”
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329 Clinician and researcher knowledge, barriers, and facilitators of patient partner research engagement to accelerate translational science by Knoll Larkin, Daniel Whibley, Tricia Piechowski, Greg Merritt, Megan Haymart, David Williams

“…In addition, to describe the strategies, our Patient Partners Program has planned for building clinician and researcher capacity to engage patient partners in clinical research. Methods/Study Population: Our program to promote authentic patient–researcher partnerships to advance clinical and translational research is grounded in participatory approaches to maximize meaningful engagement. …”
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Historical Rights of States to Maritime Water Areas and the Legal Status of the Sea of Okhotsk by V. V. Gavrilov, R. M. Nurimbetov

“…Based on the study of the international law, doctrine and practice of states, the article analyzes the content of the institution of the historical rights of the state to the sea areas, its correlation with the provisions of the 1982 UN Convention on the Law of the Sea, as well as the legal status of the Sea of Okhotsk and the possibility of its adjustment in in the context of a possible statement by Russia that it has historical rights to its water area.  MATERIALS AND METHODS. The issues raised in the article are structurally divided into three main groups. …”
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Evaluating the domains of generalism and equity, diversity and inclusion in preclinical simulated cases for targeted curricular improvements by Thomas Soroski, Kuda Hove, Lisa Steblecki, Jaime C. Yu

“…Twelve generalism and 5 EDI items were scored on a 5-point Likert scale, with higher scores indicating better demonstration of generalism or EDI within a case. …”
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Anemoside B4 mitigates endoplasmic reticulum stress-induced apoptosis post cerebral ischemia/reperfusion injury in rats by Xiaohuan Huang, Ran Deng, Chaoyue Ma, Huizhi Fei

“…This study is designed to determine whether AB4 mitigates CIRI by suppressing ERS-induced neuronal apoptosis.Materials and Methods: One hundred thirty-five male SD rats (260–290 g) were randomly assigned to five groups, with 20 rats in each group: ① Sham. ② Middle Cerebral Artery Occlusion (MCAO/R). ③AB4-L: Prior to MCAO, rats were subjected to continuous intraperitoneal injection of 1.25 mg/kg of AB4.④AB4-M: Rats were administered a continuous intraperitoneal injection of 2.5 mg/kg of AB4 prior to undergoing MCAO.⑤AB4-H: Rats were continuously intraperitoneally injected with 5 mg/kg of AB4 before MCAO. …”
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Analysis of survival of HIV-infected patients depending on various factors by D. M. Urunova, Z. I. Akhmedjanova, R. I. Akhmedjanov

“…Purpose of the study: Identification of predictors of survival of HIV-infected patients for further optimization of medical care.Materials and methods. A retrospective study of data from 458 deceased HIV-infected patients who were registered at the Republican AIDS Center from 2000 to 2021 was conducted. …”
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Implementation of a mobile app for trauma education: results from a multicenter study by Heather A Vallier, Benjamin R Childs, Mary A. Breslin, Mai P. Nguyen, Natasha M. Simske, Paul S. Whiting, Aswinkumar Vasireddy

“…The purpose of this study was to demonstrate adoption of a patient education application (app: http://bit.ly/traumaapp) at multiple sites with disparate locations and varied populations.Methods A trauma patient education application was developed at one trauma center and subsequently released at three new trauma centers. …”
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Seroprevalence and Shifting Endemicities of Hepatitis A Virus Infection in Two Contrasting Geographical Areas in Indonesia by Dwi Prasetyo, Yudith Setiati Ermaya, Gustavo Hernandez-Suarez, Adriana Guzman-Holst, Cissy B. Kartasasmita

“…The seroprevalence and endemicity status were assessed based on the age at the midpoint of population immunity (AMPI). <i>Materials and Methods:</i> A cross-sectional seroprevalence study was conducted in two contrasting areas (urban vs. rural) in Bandung, Indonesia. …”
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OpenSEA: a 3D printed planetary gear series elastic actuator for a compliant elbow joint exoskeleton by Benjamin Jenks, Benjamin Jenks, Hailey Levan, Hailey Levan, Filip Stefanovic

“…To address this, we propose a novel design of a compliant 3D-printed SEA device for elbow movement rehabilitation exoskeletons that we make openly available.MethodsWe designed a 3D-printed SEA to incorporate a planetary gear system and torsional spring, offering compliance, adaptability, and cost-effectiveness. …”
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Comparison of different magnetic resonance cholangiography techniques in living liver donors including Gd-EOB-DTPA enhanced T1-weighted sequences. by Sonja Kinner, Verena Steinweg, Stefan Maderwald, Arnold Radtke, Georgios Sotiropoulos, Michael Forsting, Tobias Schroeder

“…Aim of this study was to compare T2-weighted (T2w) and Gd-EOB-DTPA enhanced T1-weighted (T1w) magnetic resonance cholangiography (MRC) techniques in the evaluation of PLLDs.<h4>Materials and methods</h4>30 PLLDs underwent MRC on a 1.5 T Magnetom Avanto (Siemens, Erlangen, Germany) using (A) 2D T2w HASTE (Half Fourier Acquisition Single Shot Turbo Spin Echo) fat saturated (fs) in axial plane, (B) 2D T2w HASTE fs thick slices in coronal plane, (C) free breathing 3D T2w TSE (turbo spin echo) RESTORE (high-resolution navigator corrected) plus (D) maximum intensity projections (MIPs), (E) T2w SPACE (sampling perfection with application optimized contrasts using different flip angle evolutions) plus (F) MIPs and (G) T2w TSE BLADE as well as Gd-EOB-DTPA T1w images without (G) and with (H) inversion recovery. …”
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Ciclosporin A proof of concept study in patients with active, progressive HTLV-1 associated myelopathy/tropical spastic paraparesis. by Fabiola Martin, Hannah Castro, Carolyn Gabriel, Adine Adonis, Alexandra Fedina, Linda Harrison, Liz Brodnicki, Maria A Demontis, Abdel G Babiker, Jonathan N Weber, Charles R M Bangham, Graham P Taylor

“…We therefore tested the hypothesis that inhibition of T-cell activation with ciclosporin A would be safe and clinically beneficial in patients with early and/or clinically progressing HAM/TSP.<h4>Materials and methods</h4>Open label, proof of concept, pilot study of 48 weeks therapy with the calcineurin antagonist, ciclosporin A (CsA), in seven patients with 'early' (<two years) or 'progressive' (>50% deterioration in timed walk during the preceding three months) HAM/TSP. …”
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Assessment of mortality and performance status in critically ill cancer patients: A retrospective cohort study. by Esther N van der Zee, Lianne M Noordhuis, Jelle L Epker, Nikki van Leeuwen, Bas P L Wijnhoven, Dominique D Benoit, Jan Bakker, Erwin J O Kompanje

“…To aid to this decision making, we studied the survival and performance status of cancer patients 2 years following an unplanned ICU admission.<h4>Materials and methods</h4>This was a retrospective cohort study in a large tertiary referral university hospital in the Netherlands. …”
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Stem solidness as an important factor for wheat protection from European wheat stem sawfly (<i>Cephus pygmaeus</i> L.) in Altai by S. B. Lepekhov, V. A. Petin, M. V. Chebatareva

“…The effect of a solid stem on the infestation of wheat stem sawfly larvae and on agronomic traits of spring bread wheat under the conditions of Altai Territory has not been studied.Materials and methods. The study was conducted on the experimental field of the Federal Altai Scientific Centre of Agro-BioTechnologies, Barnaul, Russia, in 2019–2021. …”
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Evaluation of endocan biomarker levels in peri-implant crevicular fluid of healthy and diseased peri-implant sites: a cross-sectional study by Ahmed I. Awad, Maha A. Abou Khadr, Sabah Abdelhady, Rania Abdelaziz

“…Abstract Objective This investigation evaluates Endothelial Cell-Specific Molecule-1 (Endocan), an endothelial-derived protein, for its capacity to discriminate between healthy and pathological peri-implant tissues and its diagnostic potential in peri-implant disease. Materials and methods This cross-sectional investigation analyzed 62 peri-implant sites from 62 individuals, including 31 healthy sites, chosen according to clinical and radiographic parameters based on 2017 consensus recommendations. …”
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CAD-CAM vs. conventional denture bases: a systematic review with network meta-analysis of in vitro studies comparing strength, hardness, toughness, and elastic properties by Rohit Kunnath Menon, Hui Xin Yew, Benjamin Chen Tze Wei, Farah Mohammed Ramadan, Afraa Ibrahim Soliman, Sajesh Veettil

“…This systematic review with meta-analysis was conducted to analyze the current evidence comparing the mechanical properties of conventional and digitally fabricated denture bases from in vitro studies.Materials and methodsA systematic search was conducted in PubMed, Scopus, and Medline for in vitro studies from inception until 16 January 2025. …”
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Causes and risk factors for an acute kidney injury outbreak among children in The Gambia, June - September 2022: A case-cohort study. by Mustapha Bittaye, Jayne Byakika-Tusiime, Lionel Adisso, Boris I Pavlin, Michel Muteba, Anna H Jammeh, Ifeanyi Livinus Udenweze, Amadou Woury Jallow, Nuha Fofana, Momodou Kalisa, Sharmila Lareef, Kassa Mohammed Abbe, Patricia Eyu, James Nonde, Thierno Balde, Joseph Chukwudi Okeibunor, Otim Patrick Ramadan, Fiona Braka, Abdou Salam Gueye, Desta Alamerew Tiruneh

“…The objective of the study was to establish the likely cause of the AKI outbreak and associated risk factors.<h4>Materials and methods</h4>A case-cohort study was conducted in six of the seven regions of The Gambia. …”
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Engineering Lipid–Polymer Nanoparticles for siRNA Delivery to Cancer Cells by Arthur Manda, Abdulelah Alhazza, Hasan Uludağ, Hamidreza Montazeri Aliabadi

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A new perspective on risk factors for progressive liver fibrosis in patients with HIV, HBV, HCV superinfection by E. P. Feoktistova, D. Yu. Konstantinov

“…The aim of the study was to assess the effect on the course of liver fibrosis in HIV/HBV/HCV superinfection of the sequence of pathogens entering the human body and the time between superinfection.Materials and methods. 97 people with a verified diagnosis of HIV/HBV/HCV superinfection were subjected to a retrospective analysis depending on the timing of pathogen intake, the severity of liver fibrosis and antiviral therapy. …”
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