Semaglutide, liraglutide and tirzepatide: Comparison of effectiveness in the treatment of obesity – a literature review by Karolina Baran, Marlena Jankowska, Natalia Jańczyk, Karolina Mędrysa, Jakub Pokrzepa, Michał Presak, Gabriela Blecharz, Julia Szwech, Alicja Winkowska, Jan Machalica

“…Aim of the study The aim of this study was to compare the effectiveness of semaglutide, liraglutide and tirzepatide in reducing body weight in obesity. Materials and methods The article was created based on the PubMed and Cochrane databases. …”
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Development, validation, and usage of metrics to evaluate the quality of clinical research hypotheses by Xia Jing, Yuchun Zhou, James J. Cimino, Jay H. Shubrook, Vimla L. Patel, Sonsoles De Lacalle, Aneesa Weaver, Chang Liu

“…This study aimed to develop, test, validate, and use evaluation metrics and instruments to accurately, consistently, systematically, and conveniently assess the quality of scientific hypotheses for clinical research projects. Materials and methods Metrics development went through iterative stages, including literature review, metrics and instrument development, internal and external testing and validation, and continuous revisions in each stage based on feedback. …”
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Impact of combined at-home bleaching and whitening toothpaste use on the surface and color of a composite resin by Carolina Meneghin Barbosa, Renata Siqueira Scatolin, Waldemir Francisco Vieira-Junior, Marcia Hiromi Tanaka, Laura Nobre Ferraz

“…ObjectiveThis in vitro study aimed to evaluate the effects of different whitening toothpastes on a composite resin during at-home bleaching with 10% carbamide peroxide.Materials and MethodsSixty samples (7 mm × 2 mm) were used for color and roughness analyses, while another 60 samples (3 mm × 2 mm) were utilized to assess microhardness. …”
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Global trends and characteristics of metal–organic frameworks in cancer research: a machine-learning-based bibliometric analysis by Heyuan Niu, Haipeng Du, Zhe Ji, Xiaoping Li, Wanyi Xiao, Anqi He, Ping Yu, Gang Liu

“…This study aims to explore the potential and developmental trajectories of MOFs in cancer research through a bibliometric analysis. Methods The Web of Science Core Collection was searched for documents from its inception in 2009 to December 31, 2023. …”
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Influence of modeling agents on the surface properties of an esthetic nano-hybrid composite by Zeynep Bilge Kutuk, Ecem Erden, Damla Lara Aksahin, Zeynep Elif Durak, Alp Can Dulda

“…ObjectiveThe aim of this study was to evaluate the influence of different modeling agents on the surface microhardness (Vickers hardness number; VHN), roughness (Ra), and color change (ΔE) of a nano-hybrid composite with or without exposure to discoloration by coffee.Materials and MethodsSixty-four cylinder-shaped nano-hybrid composite specimens were prepared using a Teflon mold. …”
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COMBINED TECHNIQUES OF CAUDAL EPIDURAL BLOCK AND TRANSFORAMINAL NERVE ROOT BLOCK IN THE TREATMENT OF DEGENERATIVE DISEASES OF THE LUMBAR SPINE: A COST-EFFECTIVENESS ANALYSIS by Marília de Jesus Nogueira, Anderson Gomes Marin, Mariana Demétrio de Sousa Pontes, Carlos Fernando Pereira da Silva Herrero

“…ABSTRACT Objective: This study aims to assess cost-effectiveness of caudal epidural block with transforaminal nerve root block in the treatment of degenerative diseases of the lumbar spine. Methods: A total of 47 patients with lumbar sciatica symptoms were included. …”
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Association between Internet Gaming Disorder and Associated Parental and Peer Attachment: A Crosssectional Study among Thai Adolescents by Surachet Saelim, Tikumporn Hosiri, Somboon Hataiyusuk

“… Objective: This study examined the prevalence of Internet Gaming Disorder (IGD) and its association with parental and peer attachment among Thai adolescents, accounting for gender and developmental stages. Materials and Methods: A cross-sectional design involved 783 parent-adolescent pairs (4th-9th grade, Thailand). …”
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Assesment of bone healing after surgical management of odontogenic cysts utilizing fractal analysis—a retrospective cross-sectional study by Ayse Tas, Elif Celebi, Zeynep Çukurova Yilmaz

“…This retrospective study aimed to evaluate bone healing following the surgical removal of odontogenic cysts using fractal analysis. Materials and Methods Bone changes in 17 patients who underwent cyst enucleation were assessed using fractal dimension and lacunarity measurements on digital panoramic radiographs obtained before and six months after surgery. …”
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Sildenafil for Primary Prevention of Anthracycline-Induced Cardiac Toxicity: A Phase I/II Randomized Clinical Trial, SILDAT-TAHA6 Trial by Armin Attar, Masoumeh Heydari, Firoozeh Abtahi, Alireza Rezvani, Shirin Haghighat, Reza Vojdani, Mani Ramzi, Mehdi Dehghani, Mojtaba Karimi, Mohammad Kasaei, Shahdad Khosropanah, Mahmood Tabandeh

“…The aim of this study was to evaluate the clinical effect of sildenafil on the primary prevention of CTRCD in human. Materials and Methods. In this randomized double-blind clinical trial, the primary end point was efficacy in preventing the reduction of left ventricular ejection fraction (LVEF). …”
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Cross-Cultural Pragmatic Failure in English Language Classrooms: Development of a Multi-Dimensional Model Based on EFL Teachers’ and Learners’ Perceptions by Zahra Savadkouhi, Mahnaz Mostafaei Alaei

“…Employing an exploratory sequential mixed methods design, the researchers developed and validated the Questionnaire with 25 items on a 5-point Likert-type scale ranging from strongly disagree to strongly agree with 220 EFL teachers and learners. …”
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Diabetes mellitus type 2 correction, changes in c-peptidemia and insulinemia inconnection with ileoduodenoplasty by S. E. Podpryatov, S. S. Podpryatov, N. M. Starchak, A. V. Antonova, I. V. Satsyuk, V. P. Korchak

“…The diabetes move changes estimate and c-peptidemia and insulinemia levels changes in connection with ileoduodenoplasty. Materials and methods. C-peptiemia and insulinemia were estimated in 45 patients with diabetes mellitus type 2. …”
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Effect of transurethral resection of the prostate on renal function in patients with renal insufficiency not needing dialysis by Montadhar Hameed Nima, Mohammed Ghanim Alwan, Thaer Saleh Al-Omary

“…The purpose: to assess the effect of TURP on renal function in patients with renal insufficiency secondary to ВРН. Materials and methods. A clinical trial study was carried out in the Urology Unit at Al-Yarmouk Teaching Hospital during a period of 18 months from April 1, 2023, till the end of September 2024. …”
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Estimation of the Annual Greenhouse Gas Emissions from the Town Gas Distribution System in Hong Kong in 2022 by Daisong Chen, Tsz Lap Chan, Jin Shang

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Anticancer and Antiproliferative Effects of Combined Treatment with 5-Fluorouracil and Probiotic Lactobacillus Strains against Colorectal Cancer Cells by Sanaz Salek, Elham Moazamian, Afshin Mohammadi Bardbori Mohammadi Bardbori, Seyedeh Azra Shamsdin

“…Considering the anticancer potential of probiotic metabolites, this study assessed the anticancer effects of potential probiotic strains isolated from mule milk, camel milk, and the standard probiotic strain Lactobacillus rhamnosus GG (LGG), used alone and in combination with 5-FU, against the human colon cancer cell line (HT-29) and normal human embryonic kidney (HEK-293). Materials & Methods: Biochemical and molecular techniques were implemented to identify the strains isolated from mule and camel milk. …”
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Proximal contact areas of maxillary anterior teeth and their influence on interdental papilla by Abhay P. Kolte, Rajashri A. Kolte, Pranjali Bawankar

“…So, the present study was aimed to determine the proximal contact areas of maxillary anterior teeth and their influence on the interdental papilla. Materials and methods: In 200 periodontally healthy patients equally divided into 21–40 years (Group I) and 41–60 years (Group II) of age group amounting to a total of 1400 interdental papillae in maxillary anterior teeth were examined to compute the apicocoronal Proximal contact area (PCA), Proximal contact area proportion (PCAP), and dimensions between alveolar crest and apical contact point (D1) to assess their influence on presence or absence of interdental papilla. …”
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The effectiveness of three months EGFR-CTH therapy in palliative colorectal cancer by Maciej Pawel Jankowski, Krystyna Bratos, Tomasz Urbanowicz

“…MATERIALS AND METHODS: There were 133 (82 (62%) male and 51 (38%) female) consecutive patients with a median age of 70 (64–74) years who underwent palliative treatment due to the advanced stage of oncological gastrointestinal tract disease between 2022–2024 at the Clinical Oncology and Immuno-Oncology Department. …”
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Association between the concentration of salivary lactoferrin, smoking, and periodontal disease parameters: A randomized observational study by Hattan Mohamed Arab, Hassan Abed, Arkadiusz Dziedzic, Doaa Nadhim, Mutaz Banjar, Khalid Metwalli, Mohsen Aljabri, Marta Tanasiewicz

“…Aims: This study aimed to assess salivary lactoferrin (LF) concentration among individuals diagnosed with periodontitis (PDS) compared to a control group. Materials and Methods: A randomized, observational study enrolled 441 participants residing in Southern Sweden, aged 20 and 89 years and diagnosed with PDS. …”
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Impact of HIV infection and tuberculosis on life expectancy in Siberian Federal District regions by L. I. Levakhina, A. I. Blokh, O. A. Pasechnik, I. P. Burashnikova, N. G. Anpilova

“…To assess the impact of HIV infection and tuberculosis on life expectancy in Siberian Federal District regions for improving the allocation of health resources.Materials and Methods. We investigated the data on the number of population and mortality (stratified into 5-year age groups) in Siberian Federal District regions. …”
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Breast cancer risk assessment tool: Observations from an Indian cohort by Somesh Chandra, Shantanu Chandra, Veer Kanani

“…This observational study highlights the findings regarding Gail model for breast cancer risk in an urban cohort of Indian women. Materials and Methods: Prospectively collected data of women attending the preventive health check-up department of western India were analyzed retrospectively. …”
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Do Pediatric Nephrologists Know Their Educational Competencies? by Seçil Arslansoyu Çamlar, Hatice Şahin

“…The aim of this study was to evaluate the knowledge of pediatric nephrologists about competencies in the field of specialization. Materials and Methods: In the cross-sectional study conducted between January 2023 and 2024, the knowledge of pediatric nephrologists about specialty competencies was investigated with the two-round Delphi technique. …”
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