Organ preservation treatment of locally advanced cancer of the laryngopharynx using regional intra-arterial chemotherapy in a patient with solitary kidney by A. A. Akhundov, A. М. Mudunov, B. I. Dolgushin, М. N. Narimanov, D. A. Safarov, I. A. Trofimo, I. M. Gelfand, V. Z. Dobrokhotova, Chen Hui

“…Blokhin National Medical Research Center of Oncology with laryngopharyngeal cancer and bilateral metastases in the lymph nodes (T3N2M0,  stage IV). Use of systemic chemotherapy for this patient was limited because he had only 1 functional kidney. …”
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PET/CT WITH 68GA-FAPI46 FOR THE DETECTION OF PRIMARY AND METASTATIC LESIONS IN PATIENTS WITH DIFFERENT TYPES OF CANCER. INITIAL EXPERIENCE by Lilian Yuri Itaya Yamaga, Gustavo Borges da Silva Teles, Durval Santos, Oren Smaletz, Roberto Pestana, Poliana Biasi, Mauricio Fernandes, Solange Amorim Nogueira, Marycel Figols Barboza, Taise Vitor, Jairo Wagner

“…The diagnostic performance was high due to a favorable physiological organ distribution and low background signal leading to the detection of most metastatic lesions especially in lymph nodes, pleura, peritoneum, skeleton, liver and central nervous system. …”
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The Association Between Thromboembolic Events and ALK, ROS1, RET Rearrangements or EGFR Mutations in Patients With Advanced Lung Adenocarcinoma: A Retrospective Cohort Study by Xiaohan Qian, Mengjiao Fu, Jing Zheng, Junjun Chen, Cuihong Cai, Jianya Zhou, Jianying Zhou

“…Multivariate analysis revealed ROS1 rearrangements, the number of comorbidities, the size of mediastinal lymph nodes, and elevated C‐reactive protein (CRP) levels as TE risk factors during the peri‐diagnostic period. …”
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Neural network-based segmentation model for breast cancer X-ray screening by N. I. Rozhkova, P. G. Roitberg, A. A. Varfolomeeva, M. M. Mazo, A. N. Dobrenkii, D. S. Blinov, E. V. Sushkov, O. N. Deryabina, A. I. Sokolov

“…When comparing the results of machine segmentation and marking of images by a radiologist, it was found that the model is not inferior to the doctor in the accuracy of determining the formations, extra-focal calcifications and intraglandular lymph nodes. Conclusion. The results of this study allow considering the model as an intelligent assistant to a radiologist in the analysis of screening mammographic cases.…”
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Pre-Treatment and Pre-Brachytherapy MRI first-order Radiomic Features by a Commercial software as survival predictors in radiotherapy for cervical cancer Objectives by Wiwatchai Sittiwong, Pittaya Dankulchai, Pitchayut Wongsuwan, Tissana Prasartseree, Wajana Thaweerat, Nerisa Thornsri, Pongpop Tuntapakul

“…MRI-based contouring included T2WI and DWI images for primary tumor (GTVp) and lymph nodes (GTVn). The contours were imported to MIM software to extract first-order radiomic features. …”
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Malignant tumors of the nose and paranasal sinuses: a retrospective review of a Portuguese cancer center’s experience by L. G. Castelhano, F. A. Correia, D. F. Raposo, A. H. Campos, M. R. Melo, S. A. Pereira, M. C. Mariano, L. Ferreira, P. Montalvão, M. T. Magalhães

“…Survival was significantly decreased in non-smokers (p = 0.022), T3–4 tumors (p = 0.007), positive lymph nodes (p <0.001), nonepithelial tumors (p = 0.036) and positive margins (p = 0.032). …”
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Analysis results of surgical treatment and chemoradiotherapy with assessment of prognostic factors in localy advanced laryngeal cancer by Z. A.‑G. Radzhabova, M. A. Kotov, M. M. Girshovich, O. I. Ponomareva, E. V. Kostromina, M. A. Radzhabova, A. S. Mitrofanov, V. V. Klimenko, E. V. Levchenko

“…Metastatic lesion of the neck lymph nodes (N2–3), invasion of laryngeal cartilage, invasion of the thyroid gland and the spread of the tumor to the larynx are statistically significantly associated with lower overall and relapse-free survival.…”
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Clinicopathological features of colon cancer depending on the dMMR status of the tumor by S. S. Naumov, N. V. Krakhmal, M. N. Tarasov, M. I. Taranenko, E. V. Udut, Yu. V. Kolobovnikova, S. V. Vtorushin

“…This sign was associated with damage to regional lymph nodes (p = 0.0017). A more detailed analysis of the tumor budding phenomenon showed that in dMMR tumors, Bd1 low-grade budding (83%) predominated. …”
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First-line chemotherapy for head and neck squamous cell carcinoma. Optimal strategy by L. V. Bolotina, A. L. Kornietskaya, A. D. Kaprin, Е. Yu. Karpenko

“…The study objective is to provide a rationale for the development of an individual treatment plan for patients with locally advanced squamous cell carcinoma of the larynx, hypopharynx, and oropharynx by selecting different regimens of induction chemotherapy according to biological characteristics of the tumor and functional status of the patient.Materials and methods. We developed an individual treatment plan for a patient with stage IV moderately differentiated oropharyngeal squamous cell carcinoma (cT4N2M0) characterized by extensive local distribution, pronounced clinical symptoms of respiratory failure, and bilateral conglomerates of metastatic lymph nodes. …”
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Treatment strategy for patients with esthesioneuroblastoma and long-term outcomes by E. R. Oganyan, A. M. Mudunov, S. B. Alieva, N. A. Pirogova, A. A. Markovich, L. A. Kurbanova

“…The most significant factors negatively affecting the prognosis were as follows: T3–4 tumor, involvement of regional lymph nodes before treatment initiation, distant metastasis, grade IV tumor, and Ki-67 index >21 %.…”
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EXTRAMEDIASTINAL LESION IN PATIENTS WITH PRIMARY MEDIASTINAL B-CELL LYMPHOMA by Ya. K. Mangasarova, A. U. Magomedova, A. M. Kovrigina, I. E. Kostina, E. S. Nesterova, L. G. Gorenkova, A. E. Misyurina, O. V. Margolin, S. K. Kravchenko

“…In all cases, there is involvement of organs and tissues, but not the lymph nodes. In 18.7 % (3/16) of cases there was bone marrow involvement, confirmed by molecular and histological studies.Conclusion. …”
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Combined treatment of unresectable hilar cholangiocarcinoma with subsequent liver transplantation by D. A. Granov, I. I. Tileubergenov, V. N. Zhuikov, A. R. Sheraliev, A. A. Polikarpov, A. V. Moiseenko

“…The recipients underwent laparoscopic abdominal revision for carcinomatosis and assessment of lymph nodes in the hepatoduodenal ligament with urgent morphological examination. …”
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Optimizing prediction of metastasis among colorectal cancer patients using machine learning technology by Raoof Nopour

“…Factors including the history of IBD, family history of CRC, number of lymph nodes involved, fruit intake, and tumor size were considered as more strengthful predictors for metastasis in colorectal cancer and clinical usability. …”
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Comparative evaluation of treatment methods of neoadjuvant intra-arterial chemotherapy and chemoembolization by drug-saturated embospheres in II–IVa stages cervical cancer by Sh. G. Parsyan, A. S. Lisyanskaya, M. A. Kukanov, O. A. Smirnova, M. S. Shushaniya, G. M. Manikhas

“…Operability was higher in group of chemoinfusion (69 % versus 46.4 %) (p <0.01), and fewer patients with metastases to regional lymph nodes were revealed in this group (30.2 % versus 42 %), p <0.05. …”
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Synthesis and antituberculosis activity of N'-(2-(5-((theophylline-7'-yl)methyl)-4-R-4Н-1,2,4-triazole-3-ylthio)acetyl)isonicotinohydrazides by A. S. Gotsulya, V. V. Zazharskyi, P. O. Davydenko

“…For histological examination, the lymph nodes, pieces of spleen, liver, lungs, as well as the kidney, were taken from each mumps in regional guinea pigs and placed in 10% formalin solution. …”
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Clinical Staging and Histopathological Grading of Inguinal Squamous Cell Carcinoma in Dogs: A Case Series Study by Jiménez-Alonso AA, Pérez-Santana CG, Cazorla-Rivero SE, Rodríguez-Esparragón F, Rodríguez Grau-Bassas E

“…Clinical staging (TNM system) was performed through abdominal ultrasound and palpation of regional lymph nodes, and histopathologically, Broder grading was applied.Discussion: The survival time (ST) and disease-free interval (DFI) were analyzed, and the median ST was 738 days for Grade 1 tumors compared with 135 days for Grade 4 tumors. …”
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Clinical insights on paratuberculosis in Arabian camels (Camelus dromedarius): A review by Mohamed Tharwat, Haytham Ali, Abdulrahman A. Alkheraif

“…Sonographically, the intestinal wall is either mildly, moderately or severely thickened along with mesenteric lymph nodes (LN) enlargement. The LN capsule is either anechoic or echoic and the contents are either echogenic, anechoic or heterogenous. …”
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Comparative characteristics of the transcriptional activity of CDH1, CTNNB1, VEGFA genes and expression of proteins E-cadherin, β-catenin and VEGFA, coded by these genes in metasta... by V. A. Tumanskiy, A. V. Chepets, А. М. Kamyshnyi

“…To study the expression levels of mRNA of CDH1, CTNNB1, VEGFA genes and the expression levels of E-cadherin, β-catenin, VEGFA in non-metastatic endometrioid endometrial carcinoma (EEC) and in EEC with metastases to regional lymph nodes. Materials and methods. Immunohistochemical study of invasive рТ1-4N0Mx endometrioid endometrial carcinoma (EEC) (n=56; age – 42–83 years), invasive рТ1-4N1-2Mx EEC (n=30; age – 48–79 years), samples of normal proliferative endometrium (PE) (n=30; age – 41–62 years) was performed. …”
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Human Herpes virus 7 infections in children. Clinical and laboratory aspects by G. R. Fatkullina, V. A. Anokhin, A. R. Musina

“…The presence of such syndromes as recurrent tonsillitis, cervical lymphadenopathy or isolated enlargement of submandibular lymph nodes, periodic fever, pharyngitis, recurrent ARI in combination with hepato - and/ or splenomegaly, fatigue, and headache is often associated with HHV7. …”
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Down-staging following neoadjuvant chemo-radiotherapy for locally advanced rectal cancer: Does timing of surgery really matter? by Bhawna Sirohi, Savio George Barreto, Shraddha Patkar, Alok Gupta, Ashwin DeSouza, Sanjay Talole, Kedar Deodhar, Nitin Shetty, Reena Engineer, Mahesh Goel, Shailesh V Shrikhande

“…Median time from completion of NACTRT to surgery was 64.5 days (6-474). Median lymph nodes harvested were 10 (1-50). Overall, 22 (20%) patients achieved pCR. 26 (62%) patients in Group 1 compared to 36 (53%) in Group 2 underwent sphincter sparing surgery (SSS) (P = 0.357). …”
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