GENERAL AND SPECIFIC STRUCTURAL CHANGES OF LYMPHOID ORGANS IN THE HIGH DOSE APPLICATION OF SODIUM SELENITE by I. Putalova, O. Zayko, A.Sindireva, O. Grinenko, I. Kosheleva

“…The morphometric research of the thymus, group lymphoid nodules, mesenteric lymph nodes, spleen, and laboratory investigation of blood were performed. …”
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Consensus process to agree upon surgical quality assurance processes within a pragmatic, multicentre randomised clinical trial comparing targeted axillary dissection and axillary n... by Stuart A McIntosh, Kirsty Roberts, Lucy Culliford, Natalie S Blencowe, Kerry Avery, Jessica Harris, Shelley Potter, Sophie Rees, Yazan Masannat, Peter Barry, David Dodwell, Elsa Marques, James R Harvey, Jocelyn Lippey, Margaret Perkins, Adrienne Morgan, Katherine Fairhurst, Petra Baji, Ramsey Cutress, G Bruce Mann, Jessica Frost, Ruth Mullan, Henry Cain, Edward St John, Indrani Bhattacharya, Hannah Markham

“…Evidence that this highly morbid procedure improves survival is lacking, but approximately 30% of patients will develop lifelong complications which significantly impact their quality of life.Targeted axillary dissection (TAD) may be a safe, less morbid alternative to ANC and will be evaluated in the upcoming Targeted Axillary Dissection versus axillary node clearance in patients with POsitive axillary Lymph nodes in Early breast cancer (TADPOLE) randomised controlled trial.TAD is not currently routine practice in patients having primary surgery, so it is vital that the procedure is performed in an agreed upon, standardised way within the trial and procedure fidelity monitored to ensure the results are generalisable and will be accepted by the surgical community. …”
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Uterine sarcoma: the possibility of modeling a rare tumor and providing its morphological description by E. M. Frantsiyants, A. I. Shikhlyarova, I. V. Neskubina, I. V. Kaplieva, L. K. Trepitaki, V. A. Bandovkina, Yu. A. Pogorelova, E. I. Surikova, T. I. Moiseenko, N. D. Cheryarina, E. R. Tolmakh, A. A. Vereskunova, O. G. Ishonina, E. V. Verenikina, A. P. Menshenina

“…Unlike subcutaneous grafting of sarcoma M1, the tumor growing in the uterine horn was characterized by the presence in the abdominal cavity of many nodules and tumor dropouts on the mesentery, i. e. lymph nodes. According to the cellular composition, tumors formed from a suspension of M1 sarcoma cells injected into the right horn of the uterus were characterized by a polymorphocellular type of structure against the background of pronounced neoangiogenesis. …”
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Diagnostic and prognostic significance of detecting mutations in the <i>BRAF, TERT, RAS, RET/PTC, PAX8/PPARG</i> in the material of fine needle aspiration biopsy thyroid nodules in... by A. A. Musaelyan, S. V. Lapin, V. D. Nazarov, E. S. Kozorezova, S. L. Vorobyev, S. V. Orlov

“…The prevalence of mutations in benign formations was 4.7 %. mutations in RAS genes were also found in them in group 1, mutation BRAF V600E was associated with the presence of extrathyroid invasion (p = 0.024), vascular invasion (p = 0.018), and lymph node metastases (p = 0.018). In group 2, using the genetic panel sensitivity and specificity were equal: 36.4 and 93.9 %, respectively. positive and negative predictive values were 66.7 and 81.6 %, respectively. …”
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Development and immunobiological evaluation of nanoparticles containing an immunodominant epitope of herpes simplex virus by Gabriel M. Hilario, Fernando B. Sulczewski, Raquel Liszbinski, Larissa D. Mello, Gustavo Hagen, Tiago Fazolo, Jayme Neto, Eliane Dallegrave, Pedro Romão, Tanira Aguirre, Luiz C. Rodrigues Junior

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Liposomal structure tuned J-aggregated ICG as enhanced NIR-II imaging nanoprobe by Haoli Yu, Yuesong Wang, Yan Chen, Mengyuan Cui, Huiting Xu, Yang Liu, Mingxi Li, Min ji, Fang Yang

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NIR light-driven transformable liquid metal-based nanovaccines restrain postoperative colorectal cancer recurrence by Zheng Dai, Feng Liu, Miaodeng Liu, Yuqi Song, Hongyan Zhang, Cheng Zhou, Wenyu Liu, Xiaoqiong Li, Guobin Wang, Lin Wang, Zheng Wang

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Fabrication and functional validation of a hybrid biomimetic nanovaccine (HBNV) against KitK641E-mutant melanoma by Kishwor Poudel, Zhenyu Ji, Ching-Ni Njauw, Anpuchchelvi Rajadurai, Brijesh Bhayana, Ryan J. Sullivan, Jong Oh Kim, Hensin Tsao

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α-GalCer-LNP ehanced mRNA delivery and activates natural killer T cells for superior tumor immunotherapy by Kexin Zhang, Zhen Xu, Zexiu Xiao, Fei Cao, Jing Wang, Yuandong Xu, Winson M.J. Ma, Sihui Long, Gao-Feng Zha

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Mitochondria-targeted photothermal-chemodynamic therapy enhances checkpoint blockade immunotherapy on colon cancer by Benchao Zheng, Hongbo Wang, Shiyi Zhai, Jiangsheng Li, Kuangda Lu

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CAUSE OF RELAPSE GASTRIC CANCER PATIENTS AFTER RADICAL TREATMENT by A. G. Baryshev, V. A. Porhanov, A. Y. Popov, A. N. Lishenko, N. V. Hachaturyan, D. A. Valyakis, M. V. Bodnya

“…Material and methods. Using the Kaplan-Meier method and analysis of variance, long-term treatment outcomes were analyzed in 662 patients with gastric cancer, who underwent either limited/standard lymph node dissection (D1) or extended lymph node dissection (D2). …”
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Expression of p53 protein in Barrett’s adenocarcinoma and adenocarcinoma of the gastric cardia and antrum by Jovanović Ivan, Todorović Vera N., Milosavljević Tomica, Micev Marijan, Peško Predrag, Bjelović Miloš, Mouzas Yoannis, Tzardi Maria

“…Patients with more advanced Barrett’s adenocarcinoma and in the cases of lymph node invasion revealed tendency for the greater p53 positivity compared with the early forms and lymph node-negative cases; however, this difference was not significant according to the statistical analysis. …”
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LEVELS I–VII FOLLOWING THYROIDECTOMY FOR PAPILLARY THYROID CANCER by V. S. Parshin, A. A. Veselova, V. S. Medvedev, S. A. Ivanov, A. D. Kaprin

“…The aim of this study was to assess the potential utility of neck ultrasound in diagnosing cervical lymph node metastases (levels I–VII) in patients who underwent surgical treatment for papillary thyroid cancer.Material and Methods. …”
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THE FIRST EXPERIENCE IN USING ELASTOGRAPHY IN COMBINATION WITH ENDOBRONCHIAL ULTRASONOGRAPHY FOR MEDIASTINAL PATHOLOGY: PRELIMINARY ASSESSMENT OF FEASIBILITY AND COMPARISON OF CHAR... by I. V. Sivokozov, T. L. Silina, V. N. Korolev, P. A. Pravednikov, B. S. Lenskiy

“…A total of 8 lymph nodes and one paratracheal mass (Group 4L-7-4R-2R) were assessed in three patients. …”
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ROLE OF SURGERY IN THE TREATMENT OF SMALL CELL LUNG CARCINOMA by А. А. Aksarin, М. D. Ter-Ovanesov

“…The 5-year survival rate following systematic lymph node dissection was significantly higher than following systematic biopsy (61 % versus 24 %). …”
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DIFFUSION-WEIGHTED IMAGING FOR DIFFERENTIATING MALIGNANT FROM BENIGN MEDIASTINAL LYMPHADENOPATHY by A. V. Sudarkina, A. P. Dergilev, N. A. Gorbunov, V. V. Kozlov, Yu. A. Fokina, I. P. Klimova, P. A. Yagubkin

“…Determination of the genesis of lymphadenopathy is crucial for treatment planning and prognosis of the disease.The purpose of the study was to evaluate the diagnostic accuracy of diffusion weighted imaging (DWI) with apparent diffusion coefficient (ADC) measurements in differentiating malignant versus benign mediastinal lymphadenopathy. Material and Methods. 48 consecutive patients with at least one enlarged mediastinal lymph node revealed on CT-scans were examined on 1,5 T MR-machine with conventional images and respiratory-triggered DWI. …”
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CLASSIFICATION OF PULMONARY METASTASES: POTENTIAL APPLICATION IN CLINICAL PRACTICE by E. I. Smolenov, Yu. A. Ragulin, O. V. Pikin

“…In patients having no lymph node involvement, better results were observed in patients with a solitary site of metastasis (Ms ), with a median survival of 58 months. …”
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Crowding phenomenon in breast cancer as a prognostic factor by N. V. Krakhmal, M. V. Zavyalova, S. V. Vtorushin, L. A. Tashireva, V. M. Perelmuter

“…The phenomenon of crowding in breast cancer was shown to be associated with lymph node metastases, with intratumoral heterogeneity of particular importance. …”
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Correlation of Histological Grading with Regional Metastasis in Oral Squamous Cell Carcinoma – A Cross-Sectional Study by Ruchita Patel, Kavan Patel, Rohit Mehta, Anshit Babel, C Nandini, Mahendrakumar A. Chaudhari, Dhaval Niranjan Mehta

“…A bad prognosis for mouth cancer is indicated by cervical lymph node metastases. There is a correlation between lymph node metastases and TNM staging, Broder’s grading system, and Anneroth grading system. …”
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Kikuchi–Fujimoto disease: literature review and report of four cases by V. G. Potapenko, V. V. Baykov, А. Yu. Markova, N. B. Mikhailova, A. S. Ter‑Grigoryan, Yu. А. Krivolapov

“…According to the results of the primary analysis of lymph node tissue three patients were misdiagnosed with lymphoma. due to the unusual for lymphoid malignancy course the primary material was reviewed. …”
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