Impact of the Use of 2-Phospho-L Ascorbic Acid in the Production of Engineered Stromal Tissue for Regenerative Medicine by David Brownell, Laurence Carignan, Reza Alavi, Christophe Caneparo, Maxime Labroy, Todd Galbraith, Stéphane Chabaud, François Berthod, Laure Gibot, François Bordeleau, Stéphane Bolduc

“…This study aims to demonstrate the functional equivalence of 2-phospho-L-ascorbate (2PAA), a stable form of AA, for tissue reconstruction. …”
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The current status of nano-hydrogel preparations for osteochondral repair: Systematic Review by Abebe Feyissa Amhare, Abebe Feyissa Amhare, Lichun Qiao, Huan Deng, Jinyan Lin, Jun Wang, Wei Wang, Jing Han

“…Future work should focus on long-term validation, functional outcome measures, and development of smart, adaptive materials to support clinical translation.…”
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The role of miRNA genes participating in VHL-HIF1α in clear cell renal cell carcinoma by V. N. Pavlov, I. R. Gilyazova, A. A. Izmailov, E. A. Klimentova, I. R. Sultanov, M. A. Bermishev, Z. R. Akhmadeev, A. Kh. Nurgalieva, G. V. Ishbulatova, E. K. Khusnutdinova

“…However, further studies of the genes are needed to establish their functional significance and role in the pathogenesis of ccRCC.…”
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Carbon Monoxide Stimulates Chondrocyte Mitochondria and Protects Mitochondria During Cartilage Injury by Suryamin Liman, Madeline R. Hines, Piedad C. Gómez-Contreras, Emily Witt, Jacob S. Fisher, Kevin J. Lu, Lauren D. McNally, Alicia T. Cotoia, Maxwell Y. Sakyi, Brett A. Wagner, Michael S. Tift, Douglas Fredericks, Jessica E. Goetz, James D. Byrne, Mitchell C. Coleman

“…<b><i>Conclusions:</i></b> This study supports the hypothesis that CO functions as an antioxidant for articular chondrocytes by supporting mitochondria and intracellular GSH in the presence or absence of cartilage injury. …”
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Linguistic accuracy and authenticity of the content of the Russian version of the module of gastrointestinal symptoms of the PedsQL^™ questionnaire for pediatric patient... by Anna L. Arakelyan, Andrey N. Surkov, Aleksander A. Baranov, Leyla S. Namazova-Baranova, Valeri V. Gorev, Elena B. Moskvina, Tamara A. Skvorcova, Artem V. Nikitin, Vladislav V. Chernikov

“…Health Related Quality of Life (HRQL) is a person’s perception of the effect of a disease on physical, social and psychological functioning and wealth. Questionnaires that help assess the HRQL can give a concept of child’s state, identify arcane issues and they are of great importance for a full understanding of how the state of health affects the child. …”
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Computed tomography-derived quantitative imaging biomarkers enable the prediction of disease manifestations and survival in patients with systemic sclerosis by Gabriela Riemekasten, Felix Nensa, Hanna Grasshoff, René Hosch, Malte Maria Sieren, Lennart Berkel, Jörg Barkhausen, Roman Kloeckner, Franz Wegner

“…These parameters were analysed with regard to various clinical, laboratory, functional parameters and survival. Phenotypes were identified performing K-means cluster analysis. …”
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Characteristics of patients with chronic heart failure with mildly reduced ejection fraction: clinical and demographic aspect by M. T. Duishenalieva, A. G. Polupanov, F. T. Rysmatova, E. Zh. Myrzabekova, N. E. Esenbekova, N. Ch. Cholponbekova, E. Sh. Altymyshova, A. T. Arykova, N. B. Cheskidova, E. D. Djyshambaev

“…Type 2 diabetes mellitus was present in approximately one in five patients, regardless of the CHF phenotype. Patients with functional class III (NYHA) predominated among those with HFmrEF (54,5 %) and HFrEF (56,3 %).Conclusion. …”
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ANALYSIS OF POLYMORPHISM OF THE GENES OF THE PHASE II OF XENOBIOTICS BIOTRANSFORMATION (GSTM1, GSTT1) IN THE SHORIANS AND ALIEN POPULATION OF THE KEMEROVO REGION: THE PROBLEM OF TH... by Фаина Анисимовна Лузина, Анастасия Викторовна Дорошилова, Владимир Юрьевич Смирнов, Анастасия Сергеевна Казицкая, Ольга Николаевна Гуляева, Татьяна Константиновна Ядыкина, Анатолий Владимирович Колбаско

“…The indigenous Shorians are dominated by the frequencies of the non-mutant variants of the genes of xenobiotics biotransformation: GSTM1 (+) is 0.768, GSTT1 (+) is 0.743; the frequency of «null» functionally weakened genotypes and their combinations compared with the Europeoid population is reduced. …”
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Clinical significance of assessing ADAMTS-13 and von Willebrand factor level in COVID-19 convalescent pregnant women by N. R. Gashimova, K. N. Grigoreva, V. O. Bitsadze, L. L. Pankratyeva, J. Kh. Khizroeva, M. V. Tretyakova, Ya. M. Shammut, E. Iu. Iupatov, V. I. Tsibizova, J.-K. Gris, D. V. Blinov, A. D. Makatsariya

“…The ADAMTS-13/vWF ratio determines the pathway functioning, the risk of microcirculation disorders and clinical complications.…”
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Antioxidant activities of sea buckthorn polysaccharides and their potential application in cosmetic industry by Hao Wang, Na Cheng, Qingyuan Wu, Danjiao Fang, Faiz-Ur Rahman, Huifang Hao, Yongmin Zhang

“…Conclusion: These results showed that sea buckthorn polysaccharide has certain antioxidant activity; therefore, sea buckthorn polysaccharide has a strong potential to be applied in antioxidant and anti-aging functional cosmetics.…”
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Environmental enrichment affects immunity and reduces disease severity in pigs after co-infection, with stronger effects when applied from birth than from weaning by Brigitte G. C. de Bruijn, Ingrid Danielle Ellen van Dixhoorn, J. Elizabeth Bolhuis, Jan B. W. J. Cornelissen, Norbert Stockhofe-Zurwieden, Marion Kluivers, Johanna M. J. Rebel, Johanna M. J. Rebel

“…We investigated whether environmental enrichment applied at different life stages of pigs affects the susceptibility to and severity of disease by studying immune cell functions around weaning and during nursery, the effects of infection in ex vivo models and in vivo using a co-infection model of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) followed by an Actinobacillus pleuropneumoniae infection. …”
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Supramolecular nanofibers of natural asiaticoside for self-supporting gelation and enhanced transdermal delivery by Xixi Hu, Shuang Tian, Jiao Wang, Weixi Luo, Jiangli Yao, Rui Zhu, Yiyuan Dai, Hongyun Li, Yuhua Ma, Chen Liu, Wenping Wang

“…The hydrogel’s dual functionality (pH-responsive gelation and enhanced permeation) offers a sustainable platform for the transdermal delivery of hydrophobic phytochemicals, bridging phytochemistry and nanobiotechnology. …”
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Multifunctional physical simulation test system for deep coal rockburst development and its application by Shoujian PENG, Qingfeng XU, Jiang XU, Liang CHENG, Bin ZHOU, Yan YANG, Feng JIAO

“…In order to conduct an in-depth research on the disaster causing laws of coal-rock burst and rock burst in deep strata, a multi-functional physical simulation test system for rock burst in deep strata has been independently developed. …”
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Placental markers of miscarriage by A. A. Zhyvetska-Denysova, I. I. Vorobiova, N. Ya. Skrypchenko, S. M. Tolkach, S. M. Razdaibedin, Yu. M. Bondarenko

“…The markers of inflammation and premature labor are structural and functional changes of placenta in combination with moderate expression of TNF-α in syncytium, high expression of NK-CD56 in villous stroma, high expression of CD45/T200/LCA in the decidual membrane.…”
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GABRP Mediates GABA‐A Receptor to Shape Tumor Immunosuppressive Microenvironment and Promote Tumor Immune Escape and Corresponding Targeted Therapy by Wu Cen, Genyuan Fu, Xiaoyu Wang, Ruting Wei, Xingwang Zhou, Wei Teng, Yuanguo Ling, Jiaze Tang, Zhongan Wang, Liangzhao Chu

“…Functional studies included GABRP knockdown in glioma cells (U87/U251) via lentiviral RNAi, proliferation/migration assays (CCK‐8, scratch test), and pathway analysis. …”
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Substrate-Induced Structural Dynamics and Evolutionary Linkage of Siderophore-Iron ABC Transporters of <i>Mycobacterium tuberculosis</i> by Aisha Farhana, Abdullah Alsrhani, Hasan Ejaz, Muharib Alruwaili, Ayman A. M. Alameen, Emad Manni, Zafar Rasheed, Yusuf Saleem Khan

“…<i>Results</i>: Our findings reveal that the substrate-binding domain (SBD) of IrtA functions as an active monomer, while Rv2895c, which facilitates the uptake of siderophore-bound iron, exists in a dynamic equilibrium between dimeric and monomeric forms. …”
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Engineered Spirulina platensis for treating rheumatoid arthritis and restoring bone homeostasis by Xiao Yang, Kewei Rong, Shaotian Fu, Yangzi Yang, Shasha Liu, Chenyu Zhang, Kang Xu, Kai Zhang, Yingchun Zhu, Yongqiang Hao, Jie Zhao, Jingke Fu

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Synthesis of new nicotintaldehyde derivatives via Pd(0) catalyzed suzuki coupling with structural characterization and co-combined computational-experimental evaluation against ora... by Amanullah, Fazal Ur Rehman, Ume Aiman, Safia Obaidur Rab, Sophia Awais, Rabia Baloch, Muhammad Adeel, Niamat Ullah, Muhammad Akmal Farooq, Hafiz Amir, Ali Kharal, Muhammad Ismail, Adnan Amin

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Effect of Northwest Fermentation Agents on the Quality of Mung Bean Bread by Fermenting Mung Bean Powder by Weichao GUAN, Weijia ZHANG, Lijun DONG, Man LI, Xiling ZHANG, Chenqi GU, Xiufa HU, Xiaoming WANG, Xiaoliang HAO, Chanmin ZHENG, Yuguang ZHANG, Qingyu YANG

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Wearable Ultrasound-Imaging-Based Visual Feedback (UVF) Training for Ankle Rehabilitation of Chronic Stroke Survivors: A Proof-of-Concept Randomized Crossover Study by Yu-Yan Luo, Chen Huang, Zhen Song, Vaheh Nazari, Arnold Yu-Lok Wong, Lin Yang, Mingjie Dong, Mingming Zhang, Yong-Ping Zheng, Amy Siu-Ngor Fu, Christina Zong-Hao Ma

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